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The map label for this gene is pheA [H]

Identifier: 146339105

GI number: 146339105

Start: 2194227

End: 2195900

Strand: Direct

Name: pheA [H]

Synonym: BRADO2059

Alternate gene names: 146339105

Gene position: 2194227-2195900 (Clockwise)

Preceding gene: 146339100

Following gene: 146339106

Centisome position: 29.43

GC content: 68.7

Gene sequence:

>1674_bases
GTGATGCAACGTCTGACCACGTCGGTCCTGATCGTCGGCGGTGGGCCGTGCGGGCTGATGCTCGCCAACGAGCTCGGTCG
CCGCGGCGTGTCCGCGATCCTGGTCGACGAGAAGCCGGGTACGGCGTTCAATCCGCAGGCCAACGCGACCCAGGCGCGGA
CGATGGAGCACTACCGCCGGCTCGGCTTCGCCGGCGAGATCCGCCGCGCCGGCCTGCCGGCGGACTATCCGACCGATGTC
GCCTATTTCACGCGCTACACGGCGTACGAGCTGGCGCGCTTCCAGCTGCCGTCTGCGGCGCGGGCGACCGAACTGATCAA
GGGTCTGTCCGGCTCGTGGAGCGCGGCCGAGCTGCCGCATCGGGTGTCGCAGAAATTCGTCGAGGCGATCCTGCTGCGCC
ATGCCCGGGAGTTCGCCGGCATTCAGCTGCATTACGGCCATCGCTTGATCGGCTACGTCAGCCATGACGCTGGCATCTCC
GCCGAGGTCGAGCGTGTCGGCGATGGCGCACGCATCCAGATCGCGGCCGCTGTCCTGGTCGGCGCCGATGGCCCGCGATC
CCAAGTGCGGCAGTCTCTCGGGATCTCCTATGCCGGCACCACCGGCGTGCAGCGCGATTTCATGGGCGGCCGCATGCTCG
CCGTCTATCTCCGCGCGCCGGAGTTCTATGCTCAGGTCCCGCACGACAAGGCCTGGATGTATGTCTGCTTCAACCGCGAT
CGTCGTGCCTTCATGGCGGCCGTGAACGGCCGCGACGAGTTCGCCTTTCACACCCAGCTGCGGCCCGGCGAGGACGAGAG
CGCGATCACGGCTGATGAGGCGAAGGCCGCGTTCCAGCGCGCCTGCGGCAGCAGCATCCCGTGCGAGGTGCTGTCGCATC
TGACCTGGACCGCGGGCCATGCGCTGGTGGCCGAGAGCATGCAGCGCGGCCGGGTGTTTCTTGGTGGCGACGCGGCGCAT
CTGTTCACGCCGACCGGCGGGCTCGGCCACAACACCGCGATCGAGGACGCCGTCAATCTCGGCTGGAAGCTCGCTCACGT
GGTCAAGGGCATCAGCCCGATGGCGCTGCTCGACAGCTACGCGGCGGAGCGGCGCCCTGTGGCGCTGCGCAACACCGACT
ACGCCCGCCGGTTCGCGGATTCGCTCGGTCTGTTCGCTGCGGTTCCCGAGATCGAGGATGCGACCCAGGCGGGAGAGGAG
GCGCGCGGTGCCGCCGGCGCTTATTTCAGCCAGCACGCGCGGGCCGAGTTCAACATTCCCGGCATCACCTTCGGCGGCCG
CTATGACGGCTCCCCGATCATCGTCCCCGACGGCACCCGGCCGCCGCCGGATGCTGCCGATGTTTATGTTCCCAGCGCCT
GTCCGGGCGGGCGCGCACCGCATGCGTGGCTTGGCCCTGGCATATCGCTGTATGACCGCTTCGGCTTCGAGTGGACGCTG
CTGCATTTCGAGGGCAGCGATGTCGACAAGGACGGTCTGCAAGAGGTTGCGCGGTCGCTCGACGTCGACCTGACGATCCT
CACGCTGCCGCGTGCCCTACGCGATCTCTACGAGGCCGATCTCGCGCTCATACGTCCCGATCAGATCGTGGCCTGGCGCG
GCGGTGCGGCCCAGGCCGGCATGTTTCCGCGCGTGCTGGCGCAGGCGCTCGGGCACGGGGGCCTCGCTCGATGA

Upstream 100 bases:

>100_bases
TATGGCGCGCGCTTCGATCCGCTGCAGGAGTCGATATAGTCAGGTTGCTTGACTAATTTCCCGGACGCCATAGCATGGCC
GTCGAAACGGGAGGCGCGCG

Downstream 100 bases:

>100_bases
GGCGGACCGGACAAGGCGTGAAGAGCGCGTTAATAGATTTGGTCGTGTCGCGAGAAATCTCGCGTTGATGCTTGTGCTGA
CACAACGATCCCGGATCCGG

Product: hypothetical protein

Products: NA

Alternate protein names: Phenol hydroxylase [H]

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MMQRLTTSVLIVGGGPCGLMLANELGRRGVSAILVDEKPGTAFNPQANATQARTMEHYRRLGFAGEIRRAGLPADYPTDV
AYFTRYTAYELARFQLPSAARATELIKGLSGSWSAAELPHRVSQKFVEAILLRHAREFAGIQLHYGHRLIGYVSHDAGIS
AEVERVGDGARIQIAAAVLVGADGPRSQVRQSLGISYAGTTGVQRDFMGGRMLAVYLRAPEFYAQVPHDKAWMYVCFNRD
RRAFMAAVNGRDEFAFHTQLRPGEDESAITADEAKAAFQRACGSSIPCEVLSHLTWTAGHALVAESMQRGRVFLGGDAAH
LFTPTGGLGHNTAIEDAVNLGWKLAHVVKGISPMALLDSYAAERRPVALRNTDYARRFADSLGLFAAVPEIEDATQAGEE
ARGAAGAYFSQHARAEFNIPGITFGGRYDGSPIIVPDGTRPPPDAADVYVPSACPGGRAPHAWLGPGISLYDRFGFEWTL
LHFEGSDVDKDGLQEVARSLDVDLTILTLPRALRDLYEADLALIRPDQIVAWRGGAAQAGMFPRVLAQALGHGGLAR

Sequences:

>Translated_557_residues
MMQRLTTSVLIVGGGPCGLMLANELGRRGVSAILVDEKPGTAFNPQANATQARTMEHYRRLGFAGEIRRAGLPADYPTDV
AYFTRYTAYELARFQLPSAARATELIKGLSGSWSAAELPHRVSQKFVEAILLRHAREFAGIQLHYGHRLIGYVSHDAGIS
AEVERVGDGARIQIAAAVLVGADGPRSQVRQSLGISYAGTTGVQRDFMGGRMLAVYLRAPEFYAQVPHDKAWMYVCFNRD
RRAFMAAVNGRDEFAFHTQLRPGEDESAITADEAKAAFQRACGSSIPCEVLSHLTWTAGHALVAESMQRGRVFLGGDAAH
LFTPTGGLGHNTAIEDAVNLGWKLAHVVKGISPMALLDSYAAERRPVALRNTDYARRFADSLGLFAAVPEIEDATQAGEE
ARGAAGAYFSQHARAEFNIPGITFGGRYDGSPIIVPDGTRPPPDAADVYVPSACPGGRAPHAWLGPGISLYDRFGFEWTL
LHFEGSDVDKDGLQEVARSLDVDLTILTLPRALRDLYEADLALIRPDQIVAWRGGAAQAGMFPRVLAQALGHGGLAR
>Mature_557_residues
MMQRLTTSVLIVGGGPCGLMLANELGRRGVSAILVDEKPGTAFNPQANATQARTMEHYRRLGFAGEIRRAGLPADYPTDV
AYFTRYTAYELARFQLPSAARATELIKGLSGSWSAAELPHRVSQKFVEAILLRHAREFAGIQLHYGHRLIGYVSHDAGIS
AEVERVGDGARIQIAAAVLVGADGPRSQVRQSLGISYAGTTGVQRDFMGGRMLAVYLRAPEFYAQVPHDKAWMYVCFNRD
RRAFMAAVNGRDEFAFHTQLRPGEDESAITADEAKAAFQRACGSSIPCEVLSHLTWTAGHALVAESMQRGRVFLGGDAAH
LFTPTGGLGHNTAIEDAVNLGWKLAHVVKGISPMALLDSYAAERRPVALRNTDYARRFADSLGLFAAVPEIEDATQAGEE
ARGAAGAYFSQHARAEFNIPGITFGGRYDGSPIIVPDGTRPPPDAADVYVPSACPGGRAPHAWLGPGISLYDRFGFEWTL
LHFEGSDVDKDGLQEVARSLDVDLTILTLPRALRDLYEADLALIRPDQIVAWRGGAAQAGMFPRVLAQALGHGGLAR

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=363, Percent_Identity=25.3443526170799, Blast_Score=105, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: =1.14.13.7 [H]

Molecular weight: Translated: 60166; Mature: 60166

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQRLTTSVLIVGGGPCGLMLANELGRRGVSAILVDEKPGTAFNPQANATQARTMEHYRR
CCCCEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
LGFAGEIRRAGLPADYPTDVAYFTRYTAYELARFQLPSAARATELIKGLSGSWSAAELPH
CCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHH
RVSQKFVEAILLRHAREFAGIQLHYGHRLIGYVSHDAGISAEVERVGDGARIQIAAAVLV
HHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEEECCCCCCHHHHHCCCCCEEEEEEEEEE
GADGPRSQVRQSLGISYAGTTGVQRDFMGGRMLAVYLRAPEFYAQVPHDKAWMYVCFNRD
CCCCCHHHHHHHHCCEECCCCCCHHHHCCCCEEEEEEECCHHHHCCCCCCEEEEEEECCC
RRAFMAAVNGRDEFAFHTQLRPGEDESAITADEAKAAFQRACGSSIPCEVLSHLTWTAGH
CEEEEEEECCCCCEEEEECCCCCCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHCCH
ALVAESMQRGRVFLGGDAAHLFTPTGGLGHNTAIEDAVNLGWKLAHVVKGISPMALLDSY
HHHHHHHHCCEEEECCCCEEEECCCCCCCCCCHHHHHHHCCHHHHHHHCCCCHHHHHHHH
AAERRPVALRNTDYARRFADSLGLFAAVPEIEDATQAGEEARGAAGAYFSQHARAEFNIP
HHHCCCEEECCCHHHHHHHHHHHHEEECCCHHHHHHCCHHHCCCHHHHHHHCCCCEECCC
GITFGGRYDGSPIIVPDGTRPPPDAADVYVPSACPGGRAPHAWLGPGISLYDRFGFEWTL
CEEECCCCCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHCCCCEEEE
LHFEGSDVDKDGLQEVARSLDVDLTILTLPRALRDLYEADLALIRPDQIVAWRGGAAQAG
EEEECCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCC
MFPRVLAQALGHGGLAR
CCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMQRLTTSVLIVGGGPCGLMLANELGRRGVSAILVDEKPGTAFNPQANATQARTMEHYRR
CCCCEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
LGFAGEIRRAGLPADYPTDVAYFTRYTAYELARFQLPSAARATELIKGLSGSWSAAELPH
CCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHH
RVSQKFVEAILLRHAREFAGIQLHYGHRLIGYVSHDAGISAEVERVGDGARIQIAAAVLV
HHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEEECCCCCCHHHHHCCCCCEEEEEEEEEE
GADGPRSQVRQSLGISYAGTTGVQRDFMGGRMLAVYLRAPEFYAQVPHDKAWMYVCFNRD
CCCCCHHHHHHHHCCEECCCCCCHHHHCCCCEEEEEEECCHHHHCCCCCCEEEEEEECCC
RRAFMAAVNGRDEFAFHTQLRPGEDESAITADEAKAAFQRACGSSIPCEVLSHLTWTAGH
CEEEEEEECCCCCEEEEECCCCCCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHCCH
ALVAESMQRGRVFLGGDAAHLFTPTGGLGHNTAIEDAVNLGWKLAHVVKGISPMALLDSY
HHHHHHHHCCEEEECCCCEEEECCCCCCCCCCHHHHHHHCCHHHHHHHCCCCHHHHHHHH
AAERRPVALRNTDYARRFADSLGLFAAVPEIEDATQAGEEARGAAGAYFSQHARAEFNIP
HHHCCCEEECCCHHHHHHHHHHHHEEECCCHHHHHHCCHHHCCCHHHHHHHCCCCEECCC
GITFGGRYDGSPIIVPDGTRPPPDAADVYVPSACPGGRAPHAWLGPGISLYDRFGFEWTL
CEEECCCCCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHCCCCEEEE
LHFEGSDVDKDGLQEVARSLDVDLTILTLPRALRDLYEADLALIRPDQIVAWRGGAAQAG
EEEECCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCC
MFPRVLAQALGHGGLAR
CCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1650730 [H]