Click here to switch to the map view.

The map label for this gene is fbcH [H]

Identifier: 146339028

GI number: 146339028

Start: 2102376

End: 2104439

Strand: Direct

Name: fbcH [H]

Synonym: BRADO1977

Alternate gene names: 146339028

Gene position: 2102376-2104439 (Clockwise)

Preceding gene: 146339027

Following gene: 146339029

Centisome position: 28.19

GC content: 63.95

Gene sequence:

>2064_bases
ATGAGTGGACCTTCTACCTACCAGCCGAGCCACCCCGCCTTGAAGTGGTTCGAGCAACGACTCCCCATCATCGGCCTGGT
CCACTCGTCCTTCGTTGCCTATCCGACGCCGCGGAACCTGAACTACTGGTGGACGTTCGGCGCCATCCTGTCGCTGATGC
TGGGCGTCCAGATCGTGACCGGCGTGATCCTGGCGATGCACTACACGCCGCATGCCGATCTCGCCTTCAAGTCGGTCGAA
TTGATCGTCCGCGACGTGAATTACGGCTGGCTGCTGCGCAACATGCACGCCTGCGGCGCGTCGATGTTCTTCCTCGCCGT
CTACATCCACATGTTCCGCGGCCTCTATTACGGGTCATACAAGGCACCGCGCGAGGTACTATGGATCCTCGGCGTCATTA
TCTATCTCCTGATGATGGCCACGGGCTTCATGGGCTACGTGCTGCCGTGGGGCCAGATGAGCTTCTGGGGCGCCACCGTC
ATCACCAACCTGTTCTCGGCCGTGCCGTATTTCGGCGAGAGCATCGTGACCCTGCTGTGGGGCGGCTACTCCGTCGGTAA
CCCCACGCTGAACCGCTTCTTCGCGCTCCACTACCTGCTGCCGTTCCTGATCGCCGGCGTGGTCGTGCTGCACGTCTGGG
CGCTCCACGTCGCCGGTCAGAACAACCCGGCCGGCGTCGAGCCGAAGACCGACAAGGACATGGTGCCCTTCACGCCGTAC
GCGACGATCAAGGACTTCTTCGGCGTCACCTGCTTCCTGATCTTCTATTCCTGGTTCATCTTCTACATGCCGAACTATCT
CGGCGACGCTGACAACTATATTCCGGCCAATCCCGCCGTGACGCCCGCGCACATCGTCCCCGAATGGTACTACCTGCCGT
TCTACGCGATTCTGCGCTCGGTCCCGAACAAGCTGGCCGGCGTCATCGCGATGTTCTCGGCGATCATTGTGCTGGTGTTC
CTGCCCTGGCTCGACTCGGCCAAGACCCGCTCGAACAAGTACCGCCCGCTCGGCAAGCAGTTCTTCTGGATCTTCTTCGT
CGTCTGCGTCGGCCTCGGCTATCTCGGCGCGCAGCCGCCGGAGGGCGTTTATGTCGTGCTCGGCCGCATCCTGACCGTGC
TGTACTTCGCCTACTTCCTGATCGTGCTGCCGCTGCTCGCACGCATCGAGAGGCCGCGTCCGCTGCCGAACTCGATCGCC
GACGACGTGCTGGCCAAGTCCGGCAAGGCGATCGCCACCGCCGCGGTCGCCCTGGTTGCCGTCGTGTCGCTGTTCGCGGT
TGGCACCGGCGAGGCTCGCGCGAACGAGGGGACGCTGACCCCGCCGTCGCAAAGCTGGTCGTTCGCCGGCCCGTTCGGCA
AGTTCGATCGTGGTGCCGTGCAGCGCGGCCTGAAGATCTACAAGGAAGTCTGCTCGAACTGCCACTCGCTCAATTATGTG
GCGTTCCGCAACCTTGCCGAGCCCGGTGGGCCCGGCTACTCGCCGGCCCAGGCGGCCGCTTTCGCCTCCGAGTACAAGAT
CAAGGACGGTCCGAACGATTCGGGCGAGATGTTCGAGCGCCCGGGCCGCCCGGCGGATTATTTCCCCGCGCCGTTCCCGA
ACGAGCAGGCCGCGCGCGCCGCGAATGGTGGCGCGGCTCCACCGGACCTGTCGCTGATTGCCAAGGCGCGCTCCTACAAG
CGCGGCTTCCCCTGGTTCCTCATCGACTTCTTCACCCAGTTCCAGGAGCAGGGCCCCAACTACGTCAACGCGCTGCTGCA
GGGCTATGAAGAGACTCCGCCGCACGGCGTGACCATCCCGGACGGCTCCTATTACAACAAGTATTTCCCGGGCAACGCGA
TCAAGATGCCGCCGCCGCTGTCGGACGGGCAGGTGACGTTCGAGGACGGCTCGCCGGCGACCGTGAAGCAGTACGCCCAC
GACGTCGCGACCTTCCTGATGTGGACCGCCGAGCCGCACATGGAGGCCCGCAAGCGCCTCGGCTACCAGGTTTTCATCTT
CCTGATCATCTTCGCCGGCCTGATGTACTTCACCAAGAAGCGCGTCTGGGCCGCCGCGCACTGA

Upstream 100 bases:

>100_bases
ATCAGTTCGTTTCCGACACCAAGATCCAGATCGGCTGAGCGGACGTTACGTCCGCAAGCTCAAGCTCGATCGTGCAAGAT
AATTCTTTCAGGAACGCATC

Downstream 100 bases:

>100_bases
TCGGCGCAGCTCGTTTCGATCCTGAAAAGCCCCTGCGGGGGCTTTTTTGTTGCGCCGAGTCTGCCGTGTCGTGCCGCTCG
GCGGACGGCAGGTTTTGCCG

Product: cytochrome b/c1

Products: Q; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MSGPSTYQPSHPALKWFEQRLPIIGLVHSSFVAYPTPRNLNYWWTFGAILSLMLGVQIVTGVILAMHYTPHADLAFKSVE
LIVRDVNYGWLLRNMHACGASMFFLAVYIHMFRGLYYGSYKAPREVLWILGVIIYLLMMATGFMGYVLPWGQMSFWGATV
ITNLFSAVPYFGESIVTLLWGGYSVGNPTLNRFFALHYLLPFLIAGVVVLHVWALHVAGQNNPAGVEPKTDKDMVPFTPY
ATIKDFFGVTCFLIFYSWFIFYMPNYLGDADNYIPANPAVTPAHIVPEWYYLPFYAILRSVPNKLAGVIAMFSAIIVLVF
LPWLDSAKTRSNKYRPLGKQFFWIFFVVCVGLGYLGAQPPEGVYVVLGRILTVLYFAYFLIVLPLLARIERPRPLPNSIA
DDVLAKSGKAIATAAVALVAVVSLFAVGTGEARANEGTLTPPSQSWSFAGPFGKFDRGAVQRGLKIYKEVCSNCHSLNYV
AFRNLAEPGGPGYSPAQAAAFASEYKIKDGPNDSGEMFERPGRPADYFPAPFPNEQAARAANGGAAPPDLSLIAKARSYK
RGFPWFLIDFFTQFQEQGPNYVNALLQGYEETPPHGVTIPDGSYYNKYFPGNAIKMPPPLSDGQVTFEDGSPATVKQYAH
DVATFLMWTAEPHMEARKRLGYQVFIFLIIFAGLMYFTKKRVWAAAH

Sequences:

>Translated_687_residues
MSGPSTYQPSHPALKWFEQRLPIIGLVHSSFVAYPTPRNLNYWWTFGAILSLMLGVQIVTGVILAMHYTPHADLAFKSVE
LIVRDVNYGWLLRNMHACGASMFFLAVYIHMFRGLYYGSYKAPREVLWILGVIIYLLMMATGFMGYVLPWGQMSFWGATV
ITNLFSAVPYFGESIVTLLWGGYSVGNPTLNRFFALHYLLPFLIAGVVVLHVWALHVAGQNNPAGVEPKTDKDMVPFTPY
ATIKDFFGVTCFLIFYSWFIFYMPNYLGDADNYIPANPAVTPAHIVPEWYYLPFYAILRSVPNKLAGVIAMFSAIIVLVF
LPWLDSAKTRSNKYRPLGKQFFWIFFVVCVGLGYLGAQPPEGVYVVLGRILTVLYFAYFLIVLPLLARIERPRPLPNSIA
DDVLAKSGKAIATAAVALVAVVSLFAVGTGEARANEGTLTPPSQSWSFAGPFGKFDRGAVQRGLKIYKEVCSNCHSLNYV
AFRNLAEPGGPGYSPAQAAAFASEYKIKDGPNDSGEMFERPGRPADYFPAPFPNEQAARAANGGAAPPDLSLIAKARSYK
RGFPWFLIDFFTQFQEQGPNYVNALLQGYEETPPHGVTIPDGSYYNKYFPGNAIKMPPPLSDGQVTFEDGSPATVKQYAH
DVATFLMWTAEPHMEARKRLGYQVFIFLIIFAGLMYFTKKRVWAAAH
>Mature_686_residues
SGPSTYQPSHPALKWFEQRLPIIGLVHSSFVAYPTPRNLNYWWTFGAILSLMLGVQIVTGVILAMHYTPHADLAFKSVEL
IVRDVNYGWLLRNMHACGASMFFLAVYIHMFRGLYYGSYKAPREVLWILGVIIYLLMMATGFMGYVLPWGQMSFWGATVI
TNLFSAVPYFGESIVTLLWGGYSVGNPTLNRFFALHYLLPFLIAGVVVLHVWALHVAGQNNPAGVEPKTDKDMVPFTPYA
TIKDFFGVTCFLIFYSWFIFYMPNYLGDADNYIPANPAVTPAHIVPEWYYLPFYAILRSVPNKLAGVIAMFSAIIVLVFL
PWLDSAKTRSNKYRPLGKQFFWIFFVVCVGLGYLGAQPPEGVYVVLGRILTVLYFAYFLIVLPLLARIERPRPLPNSIAD
DVLAKSGKAIATAAVALVAVVSLFAVGTGEARANEGTLTPPSQSWSFAGPFGKFDRGAVQRGLKIYKEVCSNCHSLNYVA
FRNLAEPGGPGYSPAQAAAFASEYKIKDGPNDSGEMFERPGRPADYFPAPFPNEQAARAANGGAAPPDLSLIAKARSYKR
GFPWFLIDFFTQFQEQGPNYVNALLQGYEETPPHGVTIPDGSYYNKYFPGNAIKMPPPLSDGQVTFEDGSPATVKQYAHD
VATFLMWTAEPHMEARKRLGYQVFIFLIIFAGLMYFTKKRVWAAAH

Specific function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c [H]

COG id: COG1290

COG function: function code C; Cytochrome b subunit of the bc complex

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831119, Length=370, Percent_Identity=49.4594594594595, Blast_Score=355, Evalue=6e-98,
Organism=Homo sapiens, GI21359867, Length=251, Percent_Identity=43.4262948207171, Blast_Score=208, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17506225, Length=273, Percent_Identity=34.4322344322344, Blast_Score=139, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6226529, Length=375, Percent_Identity=53.3333333333333, Blast_Score=384, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6226532, Length=253, Percent_Identity=51.3833992094862, Blast_Score=266, Evalue=8e-72,
Organism=Saccharomyces cerevisiae, GI6324639, Length=295, Percent_Identity=43.3898305084746, Blast_Score=216, Evalue=7e-57,
Organism=Saccharomyces cerevisiae, GI6226531, Length=172, Percent_Identity=52.9069767441861, Blast_Score=186, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6226530, Length=164, Percent_Identity=46.3414634146341, Blast_Score=147, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24658292, Length=253, Percent_Identity=42.2924901185771, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21358225, Length=275, Percent_Identity=38.9090909090909, Blast_Score=185, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016175
- InterPro:   IPR005798
- InterPro:   IPR005797
- InterPro:   IPR002326
- InterPro:   IPR021157
- InterPro:   IPR009056
- InterPro:   IPR016174 [H]

Pfam domain/function: PF00032 Cytochrom_B_C; PF00033 Cytochrom_B_N; PF02167 Cytochrom_C1 [H]

EC number: 1.10.2.2

Molecular weight: Translated: 76535; Mature: 76403

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS51007 CYTC ; PS51002 CYTB_NTER ; PS51003 CYTB_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGPSTYQPSHPALKWFEQRLPIIGLVHSSFVAYPTPRNLNYWWTFGAILSLMLGVQIVT
CCCCCCCCCCHHHHHHHHCCCEEEEHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHH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CHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: QH2; ferricytochrome c

Specific reaction: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2541921; 12597275 [H]