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The map label for this gene is glpD [H]

Identifier: 146338964

GI number: 146338964

Start: 2032290

End: 2033834

Strand: Direct

Name: glpD [H]

Synonym: BRADO1908

Alternate gene names: 146338964

Gene position: 2032290-2033834 (Clockwise)

Preceding gene: 146338963

Following gene: 146338965

Centisome position: 27.25

GC content: 65.24

Gene sequence:

>1545_bases
GTGGAGCGGATCTACGATCTCGCCATTGTCGGAGGCGGCGTGAACGGCTGCGGCATCGCGCGCGATGCGGCCGGACGCGG
AAATTCCGTTTTTCTCTGCGAAATGAACGATCTTGCGAGCGGAACCTCGTCATGGTCGACGAAGCTCGTTCACGGCGGCC
TGCGCTATCTCGAATATTACGAGTTCCGGCTGGTTCGCGAGGCGCTGATCGAGCGCGAGATCCTGTGGCAGATCGCGCCC
CACATCATCCGTCCCTTGCGCTTCGTCTTGCCGCATCATTCCGGATTGCGGCCGGCTTGGCTGCTCCGCTTGGGCCTGTT
CCTGTATGACCATCTCGGCGGCCGCAAGCTGCTGCCGCCGACACGCTCGGTCAATCTGCGCAGCGACGAGGTCGGCCGGC
CCCTGATCGCCGGGCGCTACAGCAGCGGATTCGAATATTCCGATTGCTTCGTCGATGATGCGCGCCTCGTGGTGCTGACC
GCGCGCGATGCCGCCGACCGCGGCGCAGTGATCCGCACGCGCACCCGCGCCACCGAGATCCGCCAGGACGGCAGCGTCTG
GCTGGTCACGACGGAGAATATCCAGAACGGCGAGCGCGAGACCATCAAGGCGCGCGCGCTGGTCAATGCCGCCGGTCCCT
GGGTCGAGCAGGTGCTGTCGACCGGCGCCGGCGTCAATGCGAAGGCGAAGGTGCGGCTGGTGCAGGGCTCGCACATCGTG
GTGCGCAAGCTCTACGACCACGACCGCGCCTACATCTTCCAGAACGCCGATGGCCGCATCATCTTTGCGATCCCCTATCA
GCAGGATTTCACGCTGATCGGCACCACCGATCGCGACTACCAGGGCGATCCGGCCAAGGTGAAGGCGACCGACGAGGAGA
TCGCCTATCTCTGCGCCGCGCTCGGCGAATATATCGCCAAGCCGGTCACGCCGGCCGACGTGGTGTGGAGCTATTCCGGC
GTGCGGCCGCTCTATGACGACGGCGCCAGCGAGGCCAAGGCGGCTACGCGCGATTACGTGTTCGAGCTCGATACGCCCGG
CGGCCTGCCGCTGCTGTCGATCTATGGCGGCAAGATCACCACCTATCGGCGGCTGTCGGAGGAGGCCTTGGAGCGCCTCG
CGCCCTATCTGAAAGGGACGCAGGCGGAGGAGGGCTGGACCGGCAAATCGTCGCTGCCCGGCGGCGACATGAATGTGCAG
GCGATCGACGCTCTCATCACTGATCTCCGCAGGACCTGTCCGTTTCTATCAGATGCACATGCGAAGCGCATCGCACATGC
CTATGGCACGCGGGCGAAGGCCATGCTCGCGGGTGCGACATCTTCGGCCGATCTCGGCCAGGATTTTGGTGGCACCTTGA
CGGAGCGCGAAGTCAGGTACCTGATGACGAACGAGTGGGCGTTGACGGCCGAGGACATTGTGTGGCGGCGATCGAAGCTG
GGGTTGCGGATGTCGGCGGCTGAGATCGCCGCGCTCGATGCGTGGATCACGGCCAACCGCGAGCGCTCCACCGTGATGGC
GCGCGAAGCGGGAGGACGCGCATGA

Upstream 100 bases:

>100_bases
CATCCTGCGAAATTCGATTTGCTTTCGCTTTCGTTTGTGTTTAACTCGAAACCGAAAGTGAAATCGCCGATCGGAAGGCG
ATTGTCGGGGGAAGCGTCGG

Downstream 100 bases:

>100_bases
GCGTCACGCTCGATCACGTCTCGCGAATCGTCGACGGCGTCACCACGATTCGCGACGTCTCGCTGACTTTGCAGCGCGGC
ACGCTGAGCGTGCTGCTCGG

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MERIYDLAIVGGGVNGCGIARDAAGRGNSVFLCEMNDLASGTSSWSTKLVHGGLRYLEYYEFRLVREALIEREILWQIAP
HIIRPLRFVLPHHSGLRPAWLLRLGLFLYDHLGGRKLLPPTRSVNLRSDEVGRPLIAGRYSSGFEYSDCFVDDARLVVLT
ARDAADRGAVIRTRTRATEIRQDGSVWLVTTENIQNGERETIKARALVNAAGPWVEQVLSTGAGVNAKAKVRLVQGSHIV
VRKLYDHDRAYIFQNADGRIIFAIPYQQDFTLIGTTDRDYQGDPAKVKATDEEIAYLCAALGEYIAKPVTPADVVWSYSG
VRPLYDDGASEAKAATRDYVFELDTPGGLPLLSIYGGKITTYRRLSEEALERLAPYLKGTQAEEGWTGKSSLPGGDMNVQ
AIDALITDLRRTCPFLSDAHAKRIAHAYGTRAKAMLAGATSSADLGQDFGGTLTEREVRYLMTNEWALTAEDIVWRRSKL
GLRMSAAEIAALDAWITANRERSTVMAREAGGRA

Sequences:

>Translated_514_residues
MERIYDLAIVGGGVNGCGIARDAAGRGNSVFLCEMNDLASGTSSWSTKLVHGGLRYLEYYEFRLVREALIEREILWQIAP
HIIRPLRFVLPHHSGLRPAWLLRLGLFLYDHLGGRKLLPPTRSVNLRSDEVGRPLIAGRYSSGFEYSDCFVDDARLVVLT
ARDAADRGAVIRTRTRATEIRQDGSVWLVTTENIQNGERETIKARALVNAAGPWVEQVLSTGAGVNAKAKVRLVQGSHIV
VRKLYDHDRAYIFQNADGRIIFAIPYQQDFTLIGTTDRDYQGDPAKVKATDEEIAYLCAALGEYIAKPVTPADVVWSYSG
VRPLYDDGASEAKAATRDYVFELDTPGGLPLLSIYGGKITTYRRLSEEALERLAPYLKGTQAEEGWTGKSSLPGGDMNVQ
AIDALITDLRRTCPFLSDAHAKRIAHAYGTRAKAMLAGATSSADLGQDFGGTLTEREVRYLMTNEWALTAEDIVWRRSKL
GLRMSAAEIAALDAWITANRERSTVMAREAGGRA
>Mature_514_residues
MERIYDLAIVGGGVNGCGIARDAAGRGNSVFLCEMNDLASGTSSWSTKLVHGGLRYLEYYEFRLVREALIEREILWQIAP
HIIRPLRFVLPHHSGLRPAWLLRLGLFLYDHLGGRKLLPPTRSVNLRSDEVGRPLIAGRYSSGFEYSDCFVDDARLVVLT
ARDAADRGAVIRTRTRATEIRQDGSVWLVTTENIQNGERETIKARALVNAAGPWVEQVLSTGAGVNAKAKVRLVQGSHIV
VRKLYDHDRAYIFQNADGRIIFAIPYQQDFTLIGTTDRDYQGDPAKVKATDEEIAYLCAALGEYIAKPVTPADVVWSYSG
VRPLYDDGASEAKAATRDYVFELDTPGGLPLLSIYGGKITTYRRLSEEALERLAPYLKGTQAEEGWTGKSSLPGGDMNVQ
AIDALITDLRRTCPFLSDAHAKRIAHAYGTRAKAMLAGATSSADLGQDFGGTLTEREVRYLMTNEWALTAEDIVWRRSKL
GLRMSAAEIAALDAWITANRERSTVMAREAGGRA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=522, Percent_Identity=30.4597701149425, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI285002231, Length=522, Percent_Identity=30.4597701149425, Blast_Score=165, Evalue=9e-41,
Organism=Escherichia coli, GI2367226, Length=480, Percent_Identity=45.8333333333333, Blast_Score=446, Evalue=1e-126,
Organism=Escherichia coli, GI1788574, Length=490, Percent_Identity=25.9183673469388, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17509253, Length=504, Percent_Identity=30.5555555555556, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI115534726, Length=512, Percent_Identity=28.7109375, Blast_Score=141, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6322036, Length=542, Percent_Identity=26.7527675276753, Blast_Score=150, Evalue=6e-37,
Organism=Drosophila melanogaster, GI161077125, Length=528, Percent_Identity=29.1666666666667, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24653942, Length=528, Percent_Identity=29.1666666666667, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24653944, Length=528, Percent_Identity=29.1666666666667, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI20130025, Length=528, Percent_Identity=29.1666666666667, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24586295, Length=523, Percent_Identity=28.6806883365201, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI19921278, Length=506, Percent_Identity=22.3320158102767, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56685; Mature: 56685

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIYDLAIVGGGVNGCGIARDAAGRGNSVFLCEMNDLASGTSSWSTKLVHGGLRYLEYY
CCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECHHHCCCCCCHHHHHHHHHHHHHHHH
EFRLVREALIEREILWQIAPHIIRPLRFVLPHHSGLRPAWLLRLGLFLYDHLGGRKLLPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
TRSVNLRSDEVGRPLIAGRYSSGFEYSDCFVDDARLVVLTARDAADRGAVIRTRTRATEI
CCCCCCCCHHCCCCEEECCCCCCCCCCCEEECCCEEEEEEECCCCCCCCEEEEHHHHHHH
RQDGSVWLVTTENIQNGERETIKARALVNAAGPWVEQVLSTGAGVNAKAKVRLVQGSHIV
HCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEEECCEEE
VRKLYDHDRAYIFQNADGRIIFAIPYQQDFTLIGTTDRDYQGDPAKVKATDEEIAYLCAA
EHHHHCCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCEEEECHHHHHHHHHH
LGEYIAKPVTPADVVWSYSGVRPLYDDGASEAKAATRDYVFELDTPGGLPLLSIYGGKIT
HHHHHHCCCCCHHHHEECCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCEEEEECCCCCH
TYRRLSEEALERLAPYLKGTQAEEGWTGKSSLPGGDMNVQAIDALITDLRRTCPFLSDAH
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
AKRIAHAYGTRAKAMLAGATSSADLGQDFGGTLTEREVRYLMTNEWALTAEDIVWRRSKL
HHHHHHHHCCCHHEEEECCCCCCCCCCCCCCCCCHHHHHEEEECCCEEEHHHHHHHHHHC
GLRMSAAEIAALDAWITANRERSTVMAREAGGRA
CCEECHHHHHHHHHHHCCCCCHHEEEECCCCCCC
>Mature Secondary Structure
MERIYDLAIVGGGVNGCGIARDAAGRGNSVFLCEMNDLASGTSSWSTKLVHGGLRYLEYY
CCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECHHHCCCCCCHHHHHHHHHHHHHHHH
EFRLVREALIEREILWQIAPHIIRPLRFVLPHHSGLRPAWLLRLGLFLYDHLGGRKLLPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
TRSVNLRSDEVGRPLIAGRYSSGFEYSDCFVDDARLVVLTARDAADRGAVIRTRTRATEI
CCCCCCCCHHCCCCEEECCCCCCCCCCCEEECCCEEEEEEECCCCCCCCEEEEHHHHHHH
RQDGSVWLVTTENIQNGERETIKARALVNAAGPWVEQVLSTGAGVNAKAKVRLVQGSHIV
HCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEEECCEEE
VRKLYDHDRAYIFQNADGRIIFAIPYQQDFTLIGTTDRDYQGDPAKVKATDEEIAYLCAA
EHHHHCCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCEEEECHHHHHHHHHH
LGEYIAKPVTPADVVWSYSGVRPLYDDGASEAKAATRDYVFELDTPGGLPLLSIYGGKIT
HHHHHHCCCCCHHHHEECCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCEEEEECCCCCH
TYRRLSEEALERLAPYLKGTQAEEGWTGKSSLPGGDMNVQAIDALITDLRRTCPFLSDAH
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
AKRIAHAYGTRAKAMLAGATSSADLGQDFGGTLTEREVRYLMTNEWALTAEDIVWRRSKL
HHHHHHHHCCCHHEEEECCCCCCCCCCCCCCCCCHHHHHEEEECCCEEEHHHHHHHHHHC
GLRMSAAEIAALDAWITANRERSTVMAREAGGRA
CCEECHHHHHHHHHHHCCCCCHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]