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The map label for this gene is glpR [H]

Identifier: 146338963

GI number: 146338963

Start: 2031294

End: 2032127

Strand: Direct

Name: glpR [H]

Synonym: BRADO1907

Alternate gene names: 146338963

Gene position: 2031294-2032127 (Clockwise)

Preceding gene: 146338962

Following gene: 146338964

Centisome position: 27.24

GC content: 67.15

Gene sequence:

>834_bases
ATGGCCGTTCTCTCTCAACGTCAGACCGACATCCTCAACATCGCCCGCGCCTCCGGCCGCGTCATGGTGGAGGATCTGGC
GCGCCGGTTCGAAGTGTCGGCGCAGACGATCCGCAAGGATCTCAATGACCTCTGCGAGCAGCGCGCGCTGACGCGCATCC
ATGGCGGCGCCATCATCGCCTCGGGCGTCGAGAACCTCGCTTACGAGGCGCGGCGCTTCGTCGCCGCCGACGAGAAGAAG
GCGATCGGGGCGATCGCGGCGGCGCGGATTCCGAACGGGTCTTCGCTCTTCATCAACATCGGCACGACCACCGAGGAAGT
GGCCAGCGCGCTGACATCGCACCAGGATCTGCTCGTCATCACCAACAATCTCAACGTCGCGATGCTGCTCTATCCGCATC
CGCGAATCGAGGTGATCGTGGCCGGCGGCACGGTGCGGCGCTCGGACGGCGGCGTGGTCGGCTCGACGGCGACGCAACTG
ATCGGCCAGTTCAAGGTCGACTACGCGATCATCGGCGCCTCGGCGATCGACGAGGAGGGCGCGCTGCTCGACTTCGACTA
TCGCGAGGTGCAGGTCGCCCAGGCGATCATCGCCAATGCCCGCAGCGTGATGCTGGTGGCCGATTCCACCAAGCTCCACC
GCAGCGCGCCGGTCCGCATCGCCCATCTCAGCCAGATCCAGACCTTCGTCACCGACCGGCCGCTGCCTGACGGCCTCGCC
AGCCTGTGCGAGAGCCGGGGCATCGAAGTTGTCTCGGCAATGCCCGCCGACGAGGCGGAGGAGGTCGCCGAGGCAAACGA
AAGCGCCTCGCCCTCCGTGCTCCGCCGCGCCTGA

Upstream 100 bases:

>100_bases
AGCGCAAACCAGGTGATTGCTGCACTGCGCTCCGTGTCCGCTGATTGACCGTTGACGTGATCAGCATCACCATGGTGCAG
CTCGTTTCGAAAGCTTGCCC

Downstream 100 bases:

>100_bases
CCGCTCGCCATCCCTGCAGGCTGTTTGATCCCGGTTTGGGCAGGTTTTGCCCAATCTGGGGCCATCCTGCGAAATTCGAT
TTGCTTTCGCTTTCGTTTGT

Product: glycerol-3-phosphate regulon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MAVLSQRQTDILNIARASGRVMVEDLARRFEVSAQTIRKDLNDLCEQRALTRIHGGAIIASGVENLAYEARRFVAADEKK
AIGAIAAARIPNGSSLFINIGTTTEEVASALTSHQDLLVITNNLNVAMLLYPHPRIEVIVAGGTVRRSDGGVVGSTATQL
IGQFKVDYAIIGASAIDEEGALLDFDYREVQVAQAIIANARSVMLVADSTKLHRSAPVRIAHLSQIQTFVTDRPLPDGLA
SLCESRGIEVVSAMPADEAEEVAEANESASPSVLRRA

Sequences:

>Translated_277_residues
MAVLSQRQTDILNIARASGRVMVEDLARRFEVSAQTIRKDLNDLCEQRALTRIHGGAIIASGVENLAYEARRFVAADEKK
AIGAIAAARIPNGSSLFINIGTTTEEVASALTSHQDLLVITNNLNVAMLLYPHPRIEVIVAGGTVRRSDGGVVGSTATQL
IGQFKVDYAIIGASAIDEEGALLDFDYREVQVAQAIIANARSVMLVADSTKLHRSAPVRIAHLSQIQTFVTDRPLPDGLA
SLCESRGIEVVSAMPADEAEEVAEANESASPSVLRRA
>Mature_276_residues
AVLSQRQTDILNIARASGRVMVEDLARRFEVSAQTIRKDLNDLCEQRALTRIHGGAIIASGVENLAYEARRFVAADEKKA
IGAIAAARIPNGSSLFINIGTTTEEVASALTSHQDLLVITNNLNVAMLLYPHPRIEVIVAGGTVRRSDGGVVGSTATQLI
GQFKVDYAIIGASAIDEEGALLDFDYREVQVAQAIIANARSVMLVADSTKLHRSAPVRIAHLSQIQTFVTDRPLPDGLAS
LCESRGIEVVSAMPADEAEEVAEANESASPSVLRRA

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=232, Percent_Identity=44.8275862068966, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI87082344, Length=253, Percent_Identity=41.897233201581, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI1789519, Length=251, Percent_Identity=29.4820717131474, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789059, Length=254, Percent_Identity=26.3779527559055, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI226510968, Length=233, Percent_Identity=30.9012875536481, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788069, Length=234, Percent_Identity=26.4957264957265, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790753, Length=225, Percent_Identity=28.4444444444444, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=26.6375545851528, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787540, Length=233, Percent_Identity=27.4678111587983, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787063, Length=231, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 29611; Mature: 29480

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLSQRQTDILNIARASGRVMVEDLARRFEVSAQTIRKDLNDLCEQRALTRIHGGAIIA
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
SGVENLAYEARRFVAADEKKAIGAIAAARIPNGSSLFINIGTTTEEVASALTSHQDLLVI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEE
TNNLNVAMLLYPHPRIEVIVAGGTVRRSDGGVVGSTATQLIGQFKVDYAIIGASAIDEEG
ECCCCEEEEEECCCCEEEEEECCEEEECCCCEECHHHHHHHHHHHHCEEEEECCCCCCCC
ALLDFDYREVQVAQAIIANARSVMLVADSTKLHRSAPVRIAHLSQIQTFVTDRPLPDGLA
CEEECCHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCEEHHHHHHHHHHHHCCCCCHHHH
SLCESRGIEVVSAMPADEAEEVAEANESASPSVLRRA
HHHHHCCCEEEECCCCCHHHHHHHCCCCCCCHHHHCC
>Mature Secondary Structure 
AVLSQRQTDILNIARASGRVMVEDLARRFEVSAQTIRKDLNDLCEQRALTRIHGGAIIA
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
SGVENLAYEARRFVAADEKKAIGAIAAARIPNGSSLFINIGTTTEEVASALTSHQDLLVI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEE
TNNLNVAMLLYPHPRIEVIVAGGTVRRSDGGVVGSTATQLIGQFKVDYAIIGASAIDEEG
ECCCCEEEEEECCCCEEEEEECCEEEECCCCEECHHHHHHHHHHHHCEEEEECCCCCCCC
ALLDFDYREVQVAQAIIANARSVMLVADSTKLHRSAPVRIAHLSQIQTFVTDRPLPDGLA
CEEECCHHHHHHHHHHHHCCCEEEEEECCCHHHCCCCEEHHHHHHHHHHHHCCCCCHHHH
SLCESRGIEVVSAMPADEAEEVAEANESASPSVLRRA
HHHHHCCCEEEECCCCCHHHHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]