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The map label for this gene is tdcD [H]

Identifier: 146338932

GI number: 146338932

Start: 1997339

End: 1998526

Strand: Direct

Name: tdcD [H]

Synonym: BRADO1872

Alternate gene names: 146338932

Gene position: 1997339-1998526 (Clockwise)

Preceding gene: 146338929

Following gene: 146338933

Centisome position: 26.79

GC content: 63.72

Gene sequence:

>1188_bases
ATGACCACGCAGCACATCCTGACGCTCAACGCCGGTTCCTCCTCGATCAAGTTCGCATTGTTCGAACACGACGCCGGCCC
GCGTGAGACGATGCGCGGCCAGATCGAGGGGCTCGGTAGCGCCGCGCCGCATCTCCAGGCCAGGCTGAGGGGCGCGAGCT
TGAGAGACGAGCCGCTCGATGCGAGGCGCGCGACCGATCATGAAACAGCGCTGGCCGTGGTGATCGATGTGCTGCAAAGC
GCCGTCGGTCGGACGACGGTCGATGCGATCGGCCATCGCATCGTGCATGGCGGACTCGTCTTCACCCAGCCGATCGTCAT
CGCCGATGATGTCCCAGCCCGGCTCGAGACGCTCAATCCGTTGGCGCCGTTGCATCAGCCTCACAATCTCGCCGGGTTGC
GCGCCGCGCACCGTGCCTTTCCCGACGCGCTTCAGGTCGCCTGCTTCGACACCGCCTTTCACCGCACCCATCCCTGGGTG
AGCGACACTTACGCCCTGCCGCGGAGGCTTTATGATGAGGGCGTGCGTCGCTATGGCTTTCACGGCCTGTCCTATGAGTA
CGTGGTCTCGCGCCTCAAGGAGATCGCGCCGCGGGAGGAAAAGGGGCGTGTGGTCGTCATGCATCTCGGCAACGGCGCCT
CGATGTGCGCGATCCGCGACGGACGGAGCATCGGCTCGTCGATGGGCTTTACCGCGCTCGATGGCCTGCCGATGGGGACG
CGCTGCGGCCAGCTGGATCCCGGCGTCGTTCTCTATCTGCTGCAAGAGAAGGGAATGACGGCCGAGGCCGTCACTGATCT
GCTTTACAATCATTCGGGCCTCAAGGGCCTTTCGGGATTGTCGCAGGACATGCGCGAGCTGGAGCAGGCCGGAACGGCGG
AGGCGCGACAGGCAATCCATTATTTTGTCGACCGGATCAGACGTGAGATCGGCGCCATGGCGGCGGTGCTTTCCGGGCTC
GATGCCGTCGTGTTCTGCGGCGGGATCGGCGAGCACGCCTGGCAAGTCCGGGAGAGCGTCTGTGAAGGATTTGATTGGCT
TGGCATCGCGTTGGACAAAAGCCGGAATCGCGCCGGTGAAACCGTGATCTCGTCGGATGACTCCCGGGTTCGAATATTTG
TCATCAGCACCGACGAGGAGATGATGATCGCCCAGCACGCTGCAGAGCTGCTCGACGAGCGAAGGTAA

Upstream 100 bases:

>100_bases
GTGCAACCTAGCGTTTTATTTGTCTTCGGGGCGTCATGAAAATAAGTCGTATTTTCCGCATTTTGCGCCTTGGCGCGACG
TCGCAGCGAGGGCCGGCCGC

Downstream 100 bases:

>100_bases
GGACCGGTGTGCCGGCCAGATCTTCCGATTTGCCGCTTGCATGTGCTGCCTTTTTGGTATCTCCAGGATGAAAGAACAAA
TGACCGGGCAGGAACACGAT

Product: propionate kinase/acetate kinase C, anaerobic

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MTTQHILTLNAGSSSIKFALFEHDAGPRETMRGQIEGLGSAAPHLQARLRGASLRDEPLDARRATDHETALAVVIDVLQS
AVGRTTVDAIGHRIVHGGLVFTQPIVIADDVPARLETLNPLAPLHQPHNLAGLRAAHRAFPDALQVACFDTAFHRTHPWV
SDTYALPRRLYDEGVRRYGFHGLSYEYVVSRLKEIAPREEKGRVVVMHLGNGASMCAIRDGRSIGSSMGFTALDGLPMGT
RCGQLDPGVVLYLLQEKGMTAEAVTDLLYNHSGLKGLSGLSQDMRELEQAGTAEARQAIHYFVDRIRREIGAMAAVLSGL
DAVVFCGGIGEHAWQVRESVCEGFDWLGIALDKSRNRAGETVISSDDSRVRIFVISTDEEMMIAQHAAELLDERR

Sequences:

>Translated_395_residues
MTTQHILTLNAGSSSIKFALFEHDAGPRETMRGQIEGLGSAAPHLQARLRGASLRDEPLDARRATDHETALAVVIDVLQS
AVGRTTVDAIGHRIVHGGLVFTQPIVIADDVPARLETLNPLAPLHQPHNLAGLRAAHRAFPDALQVACFDTAFHRTHPWV
SDTYALPRRLYDEGVRRYGFHGLSYEYVVSRLKEIAPREEKGRVVVMHLGNGASMCAIRDGRSIGSSMGFTALDGLPMGT
RCGQLDPGVVLYLLQEKGMTAEAVTDLLYNHSGLKGLSGLSQDMRELEQAGTAEARQAIHYFVDRIRREIGAMAAVLSGL
DAVVFCGGIGEHAWQVRESVCEGFDWLGIALDKSRNRAGETVISSDDSRVRIFVISTDEEMMIAQHAAELLDERR
>Mature_394_residues
TTQHILTLNAGSSSIKFALFEHDAGPRETMRGQIEGLGSAAPHLQARLRGASLRDEPLDARRATDHETALAVVIDVLQSA
VGRTTVDAIGHRIVHGGLVFTQPIVIADDVPARLETLNPLAPLHQPHNLAGLRAAHRAFPDALQVACFDTAFHRTHPWVS
DTYALPRRLYDEGVRRYGFHGLSYEYVVSRLKEIAPREEKGRVVVMHLGNGASMCAIRDGRSIGSSMGFTALDGLPMGTR
CGQLDPGVVLYLLQEKGMTAEAVTDLLYNHSGLKGLSGLSQDMRELEQAGTAEARQAIHYFVDRIRREIGAMAAVLSGLD
AVVFCGGIGEHAWQVRESVCEGFDWLGIALDKSRNRAGETVISSDDSRVRIFVISTDEEMMIAQHAAELLDERR

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=395, Percent_Identity=41.0126582278481, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1788633, Length=402, Percent_Identity=38.5572139303483, Blast_Score=245, Evalue=4e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 43159; Mature: 43027

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQHILTLNAGSSSIKFALFEHDAGPRETMRGQIEGLGSAAPHLQARLRGASLRDEPLD
CCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCC
ARRATDHETALAVVIDVLQSAVGRTTVDAIGHRIVHGGLVFTQPIVIADDVPARLETLNP
HHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCEEEECCCCHHHHHCCC
LAPLHQPHNLAGLRAAHRAFPDALQVACFDTAFHRTHPWVSDTYALPRRLYDEGVRRYGF
CCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
HGLSYEYVVSRLKEIAPREEKGRVVVMHLGNGASMCAIRDGRSIGSSMGFTALDGLPMGT
CCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEECCCHHCCCCCCHHHCCCCCCC
RCGQLDPGVVLYLLQEKGMTAEAVTDLLYNHSGLKGLSGLSQDMRELEQAGTAEARQAIH
CCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
YFVDRIRREIGAMAAVLSGLDAVVFCGGIGEHAWQVRESVCEGFDWLGIALDKSRNRAGE
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
TVISSDDSRVRIFVISTDEEMMIAQHAAELLDERR
CEEECCCCEEEEEEEECCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTQHILTLNAGSSSIKFALFEHDAGPRETMRGQIEGLGSAAPHLQARLRGASLRDEPLD
CCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCC
ARRATDHETALAVVIDVLQSAVGRTTVDAIGHRIVHGGLVFTQPIVIADDVPARLETLNP
HHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCEEEECCCCHHHHHCCC
LAPLHQPHNLAGLRAAHRAFPDALQVACFDTAFHRTHPWVSDTYALPRRLYDEGVRRYGF
CCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
HGLSYEYVVSRLKEIAPREEKGRVVVMHLGNGASMCAIRDGRSIGSSMGFTALDGLPMGT
CCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEECCCHHCCCCCCHHHCCCCCCC
RCGQLDPGVVLYLLQEKGMTAEAVTDLLYNHSGLKGLSGLSQDMRELEQAGTAEARQAIH
CCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
YFVDRIRREIGAMAAVLSGLDAVVFCGGIGEHAWQVRESVCEGFDWLGIALDKSRNRAGE
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
TVISSDDSRVRIFVISTDEEMMIAQHAAELLDERR
CEEECCCCEEEEEEEECCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA