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The map label for this gene is ygfU [H]

Identifier: 146338801

GI number: 146338801

Start: 1855869

End: 1857266

Strand: Reverse

Name: ygfU [H]

Synonym: BRADO1735

Alternate gene names: 146338801

Gene position: 1857266-1855869 (Counterclockwise)

Preceding gene: 146338802

Following gene: 146338799

Centisome position: 24.91

GC content: 67.38

Gene sequence:

>1398_bases
ATGAGCAACGACGTTCATCCGGTCGACGAGATGCTGCCCGTGCCGAAGCTGCTGGCGCTCGGGCTGCAGCACGTGCTGGT
GATGTATGCGGGCGCGGTTGCCGTGCCGCTGATCATCGGCCGCGCCCTGAAGCTGCCGCCGGAAGATGTCGCCTTCCTGA
TCAGCGCCGACCTGTTCGCCTGCGGCCTCGCCACGCTGGTGCAATGTATCGGCTTCCCCGGCGTCGGCATCCGCCTGCCG
GTCATGATGGGCGTCACCTTCGCCTCCGTTGGCCCGATGCTGTCGATGGCCGCCTCGCCCGAAATCGGCCTGCTCGGCAT
CTATGGCTCGGTGATCGCCGCTGGCCTCTTCGGCATCATCGTCGCCCCCTTCATCAGCCGGCTGCTGCCGCTGTTTCCGC
CTGTCGTGACCGGCACCATCATCCTGATCATCGGCATCTCGCTGATGCGCGTCGGCATCAACTGGGCCGGCGGCGGCCTG
CCGACGATCACCAAGGTCGTCGACGGCGCGCGTGGCGCGTTTCCCAATCCCGACTATGGCCAGCTGCAGGGCCTCGGCAT
CGCGCTGTTCGTGCTGCTGTTCATCCTCGGCCTGATCAAATGGGGCACCGGCTTCGTCGCCAACGTCTCGGTGCTGCTCG
GCATTATCGCCGGCGCGGTGGTCGCGACCGTGCTCGGCGTGATGCATTTCGACAAGGTCGCCGCGGCGCCGTGGGGCGCG
CTGGTGTTTCCCTTCAAGTTCGGCATCCCGCAATTCTCGCCGGTGCCGATCGCGACGATGTGCATCGTCATGATCGTGGT
GATGATCGAGTCGCTCGGCATGTTCCTCGCCCTCGGCGAGATGACCGGCAAGACCGTCGATCGCGAGGCGCTGTCGCGCG
GCCTGCGCGCCGACGGCGTCGGCACGCTGCTCGGCGGCCTCTTCAACACCTTTCCCTATACGTCGTTCTCGCAGAATGTC
GGCCTTGTCTCGGTCACCGGCGTGCGCACGCGCTGGGTCACGATCACCGGCGGCGCCATCATGCTGCTGCTCGGCCTGCT
GCCGAAGATGGCCGCGCTGGTCGAAGCCGTGCCGCAGGTCGTGCTCGGCGGCGCCGGCCTCGTGATGTTCGGCATGGTGG
CGGCGACCGGCGCGCGCATCCTCGCCACCGTCGACTTCAAGACCAACCGCTTCAACTTGTTCATCGTCGCGATCGCAGTC
GGCTTCGGCATGATTCCGCTCGCGGCGCCCGGCTTCTTCCACAACCTGCCGAAGGACCTGCAGCCGCTGCTCGAGTCCGG
CATCCTGCTCTGCGCCGTCGTCGCGGTGCTGCTGAACGCGTTCTTCAACGGGCTCGGCAGCGGTAAGACCGCGGAGGCCG
ACGCTGCGGCCGCGGCGTCCTCCGCGCAGCACGTGTGA

Upstream 100 bases:

>100_bases
TTCACGGCGGTGCCGTTCAAGCCGGACCGGCTGTTTCCACAGCTGCAGGAGAGGTTCGGGGCGTGAGATCATTGTGGGGA
CCGTGCGGGGGGGACATGAA

Downstream 100 bases:

>100_bases
CGATGCGGAGGTCTGCGCTACGGCTTGGGCCGGCGATCGTAGGACCAGCCGAACAGGCCGCTCCGCTCGGTCTCGGGCTC
CGGCTCGGCCGCCGGAGCGG

Product: purine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSNDVHPVDEMLPVPKLLALGLQHVLVMYAGAVAVPLIIGRALKLPPEDVAFLISADLFACGLATLVQCIGFPGVGIRLP
VMMGVTFASVGPMLSMAASPEIGLLGIYGSVIAAGLFGIIVAPFISRLLPLFPPVVTGTIILIIGISLMRVGINWAGGGL
PTITKVVDGARGAFPNPDYGQLQGLGIALFVLLFILGLIKWGTGFVANVSVLLGIIAGAVVATVLGVMHFDKVAAAPWGA
LVFPFKFGIPQFSPVPIATMCIVMIVVMIESLGMFLALGEMTGKTVDREALSRGLRADGVGTLLGGLFNTFPYTSFSQNV
GLVSVTGVRTRWVTITGGAIMLLLGLLPKMAALVEAVPQVVLGGAGLVMFGMVAATGARILATVDFKTNRFNLFIVAIAV
GFGMIPLAAPGFFHNLPKDLQPLLESGILLCAVVAVLLNAFFNGLGSGKTAEADAAAAASSAQHV

Sequences:

>Translated_465_residues
MSNDVHPVDEMLPVPKLLALGLQHVLVMYAGAVAVPLIIGRALKLPPEDVAFLISADLFACGLATLVQCIGFPGVGIRLP
VMMGVTFASVGPMLSMAASPEIGLLGIYGSVIAAGLFGIIVAPFISRLLPLFPPVVTGTIILIIGISLMRVGINWAGGGL
PTITKVVDGARGAFPNPDYGQLQGLGIALFVLLFILGLIKWGTGFVANVSVLLGIIAGAVVATVLGVMHFDKVAAAPWGA
LVFPFKFGIPQFSPVPIATMCIVMIVVMIESLGMFLALGEMTGKTVDREALSRGLRADGVGTLLGGLFNTFPYTSFSQNV
GLVSVTGVRTRWVTITGGAIMLLLGLLPKMAALVEAVPQVVLGGAGLVMFGMVAATGARILATVDFKTNRFNLFIVAIAV
GFGMIPLAAPGFFHNLPKDLQPLLESGILLCAVVAVLLNAFFNGLGSGKTAEADAAAAASSAQHV
>Mature_464_residues
SNDVHPVDEMLPVPKLLALGLQHVLVMYAGAVAVPLIIGRALKLPPEDVAFLISADLFACGLATLVQCIGFPGVGIRLPV
MMGVTFASVGPMLSMAASPEIGLLGIYGSVIAAGLFGIIVAPFISRLLPLFPPVVTGTIILIIGISLMRVGINWAGGGLP
TITKVVDGARGAFPNPDYGQLQGLGIALFVLLFILGLIKWGTGFVANVSVLLGIIAGAVVATVLGVMHFDKVAAAPWGAL
VFPFKFGIPQFSPVPIATMCIVMIVVMIESLGMFLALGEMTGKTVDREALSRGLRADGVGTLLGGLFNTFPYTSFSQNVG
LVSVTGVRTRWVTITGGAIMLLLGLLPKMAALVEAVPQVVLGGAGLVMFGMVAATGARILATVDFKTNRFNLFIVAIAVG
FGMIPLAAPGFFHNLPKDLQPLLESGILLCAVVAVLLNAFFNGLGSGKTAEADAAAAASSAQHV

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=462, Percent_Identity=26.4069264069264, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI40316845, Length=462, Percent_Identity=26.4069264069264, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI44680145, Length=458, Percent_Identity=26.2008733624454, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI44680143, Length=462, Percent_Identity=25.974025974026, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI87082181, Length=438, Percent_Identity=55.4794520547945, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI1790087, Length=453, Percent_Identity=27.5938189845475, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI87082178, Length=454, Percent_Identity=27.3127753303965, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI87081818, Length=420, Percent_Identity=29.7619047619048, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788843, Length=408, Percent_Identity=27.4509803921569, Blast_Score=109, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17558856, Length=490, Percent_Identity=24.2857142857143, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17541904, Length=448, Percent_Identity=25, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17542260, Length=184, Percent_Identity=25.5434782608696, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71993493, Length=450, Percent_Identity=20.8888888888889, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17542262, Length=434, Percent_Identity=22.3502304147465, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21356175, Length=433, Percent_Identity=24.7113163972286, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47980; Mature: 47849

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
SNDVHPVDEMLPVPKLLALGLQHVLVMYAGAVAVPLIIGRALKLPPEDVAFLISADLFA
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH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HHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]