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The map label for this gene is mdtA [H]

Identifier: 146338795

GI number: 146338795

Start: 1849612

End: 1850733

Strand: Reverse

Name: mdtA [H]

Synonym: BRADO1729

Alternate gene names: 146338795

Gene position: 1850733-1849612 (Counterclockwise)

Preceding gene: 146338797

Following gene: 146338794

Centisome position: 24.82

GC content: 67.2

Gene sequence:

>1122_bases
ATGACCTCAGTTCTGCGATCCCCACCTCCTCCTCTTCCGCGCCGGCGTCGGCTGGCGGCGGCGGGCTGTGCCGCGATCGG
GCTGCTGCTTGCGGGCTGCGACCAAAAGGCGGCCGTCACCGCGCAACCGGTTCGGCTGGTGCAGACCCAGATCGTCAAGC
TGTCGGAGCGGCGGCAGTCGATCACGCTCACAGGCGACGTGCAGGCGCGCGTGCTGGCCGAGCTGTCGTTCCGGGTGAGC
GGCCGGGTCACCGAGCGGCTTGTCGAGGTCGGTGCGCAGGTCAAGGCCGGCCAGTTGCTCGCCCGGATCGATCCCGCGGA
GCAGCAGGCCGATCTCGACTCGGCACAGGCTGCGGTTGCTGCGGCGGAGTCGCAGGTCAAGGTAGCGACCTCCAACTTCA
ACCGGCAGCAGACCTTGATCACGAGCGGGTTCACGACCCGCGCGACCTTCGACCAGGCGCAGGAGACGCTGCGCACGGCG
GAAGGCTCGCTGGAATCCGCGAAAGCACAACTCGGCACCGCGAAGGACGCGCTGACCTACACAGAGCTTCGCGCCGATGC
CGACGGCACCATCACCGCGCGCAATATCGAGGTGGGCCAGGTCGCGCAAGCCGGGCAATCGGTGTTCACGCTCGCGCATG
ACGGCAACCGCGACGCCGTGATCGACGTCTACGAAGCGGCGCTGTCGCTCAAGTTCGACGACAGCAAGGTTGCGCTGGCG
CTGCTGTCGGACCCCTCCGTGACCGCGAAGGGCACCGTGCGCGAGGTCTCGCCGACCATCGACGCAAAATCCGGCACCGT
CCGCATCAAGATCGCGATCGAGAATCCATCGCCGGAGATGACCCTCGGCAGCGCCGTGTCGGCCACCGGCTTCATCAAGC
CGGAGCAGCGCATCGTGCTGCCGTGGAGCGCGCTGACCGCGGCGAGCAAGACGCCGGCGGTCTGGCTCGTCAATGCCACC
GACAAGACGGTGTCCCTGAAACCGATCAAGATCGAGGATTACGAGACCGGCACGATCGTCGTTTCGGCCGGGCTTGAACC
TGGCGACCGCGTCGTGACCGACGGCGGCAAGCTCTTGAGCATCGGCCAGCAGATCACGTTCAACGAGGAGAAGCGGTCGT
GA

Upstream 100 bases:

>100_bases
ACAGACGACCACCGTCCGCGAATTCCGGGCGAAACAGACGACCGCGTCCCGGTCGGATCAACGCTCCGTCAACCATTGCT
TTGGGCCCGAACGTGCAACC

Downstream 100 bases:

>100_bases
TGACGCCGATGCGTTGTGTTGTTTCGCTTGGTGCGCTCGCCGTGCTCGCCGGCTGCAACGAGAAGGCCGCGGCGCCGGAG
CCGGTCCGGCCGGTGCTGTC

Product: RND family mulitdrug efflux protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MTSVLRSPPPPLPRRRRLAAAGCAAIGLLLAGCDQKAAVTAQPVRLVQTQIVKLSERRQSITLTGDVQARVLAELSFRVS
GRVTERLVEVGAQVKAGQLLARIDPAEQQADLDSAQAAVAAAESQVKVATSNFNRQQTLITSGFTTRATFDQAQETLRTA
EGSLESAKAQLGTAKDALTYTELRADADGTITARNIEVGQVAQAGQSVFTLAHDGNRDAVIDVYEAALSLKFDDSKVALA
LLSDPSVTAKGTVREVSPTIDAKSGTVRIKIAIENPSPEMTLGSAVSATGFIKPEQRIVLPWSALTAASKTPAVWLVNAT
DKTVSLKPIKIEDYETGTIVVSAGLEPGDRVVTDGGKLLSIGQQITFNEEKRS

Sequences:

>Translated_373_residues
MTSVLRSPPPPLPRRRRLAAAGCAAIGLLLAGCDQKAAVTAQPVRLVQTQIVKLSERRQSITLTGDVQARVLAELSFRVS
GRVTERLVEVGAQVKAGQLLARIDPAEQQADLDSAQAAVAAAESQVKVATSNFNRQQTLITSGFTTRATFDQAQETLRTA
EGSLESAKAQLGTAKDALTYTELRADADGTITARNIEVGQVAQAGQSVFTLAHDGNRDAVIDVYEAALSLKFDDSKVALA
LLSDPSVTAKGTVREVSPTIDAKSGTVRIKIAIENPSPEMTLGSAVSATGFIKPEQRIVLPWSALTAASKTPAVWLVNAT
DKTVSLKPIKIEDYETGTIVVSAGLEPGDRVVTDGGKLLSIGQQITFNEEKRS
>Mature_372_residues
TSVLRSPPPPLPRRRRLAAAGCAAIGLLLAGCDQKAAVTAQPVRLVQTQIVKLSERRQSITLTGDVQARVLAELSFRVSG
RVTERLVEVGAQVKAGQLLARIDPAEQQADLDSAQAAVAAAESQVKVATSNFNRQQTLITSGFTTRATFDQAQETLRTAE
GSLESAKAQLGTAKDALTYTELRADADGTITARNIEVGQVAQAGQSVFTLAHDGNRDAVIDVYEAALSLKFDDSKVALAL
LSDPSVTAKGTVREVSPTIDAKSGTVRIKIAIENPSPEMTLGSAVSATGFIKPEQRIVLPWSALTAASKTPAVWLVNATD
KTVSLKPIKIEDYETGTIVVSAGLEPGDRVVTDGGKLLSIGQQITFNEEKRS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=300, Percent_Identity=27.3333333333333, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789929, Length=363, Percent_Identity=26.7217630853994, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786668, Length=360, Percent_Identity=28.3333333333333, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789665, Length=357, Percent_Identity=26.6106442577031, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87081796, Length=364, Percent_Identity=24.7252747252747, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081951, Length=148, Percent_Identity=31.7567567567568, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787013, Length=267, Percent_Identity=28.0898876404494, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39454; Mature: 39323

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVLRSPPPPLPRRRRLAAAGCAAIGLLLAGCDQKAAVTAQPVRLVQTQIVKLSERRQS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCE
ITLTGDVQARVLAELSFRVSGRVTERLVEVGAQVKAGQLLARIDPAEQQADLDSAQAAVA
EEEECCCHHEEEEHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCCCHHHCCCHHHHHHHH
AAESQVKVATSNFNRQQTLITSGFTTRATFDQAQETLRTAEGSLESAKAQLGTAKDALTY
HHCCEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHEE
TELRADADGTITARNIEVGQVAQAGQSVFTLAHDGNRDAVIDVYEAALSLKFDDSKVALA
EHEECCCCCEEEEECCCHHHHHHCCCEEEEEEECCCCCCEEEEEEEHEEEEECCCEEEEE
LLSDPSVTAKGTVREVSPTIDAKSGTVRIKIAIENPSPEMTLGSAVSATGFIKPEQRIVL
EECCCCCCCCCCEEECCCCEECCCCEEEEEEEEECCCCCEEECCCCCCCCCCCCCCEEEE
PWSALTAASKTPAVWLVNATDKTVSLKPIKIEDYETGTIVVSAGLEPGDRVVTDGGKLLS
EHHHHHCCCCCCEEEEEECCCCEEEEEEEEEECCCCCEEEEECCCCCCCEEEECCCCEEE
IGQQITFNEEKRS
ECCEEECCHHCCC
>Mature Secondary Structure 
TSVLRSPPPPLPRRRRLAAAGCAAIGLLLAGCDQKAAVTAQPVRLVQTQIVKLSERRQS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCE
ITLTGDVQARVLAELSFRVSGRVTERLVEVGAQVKAGQLLARIDPAEQQADLDSAQAAVA
EEEECCCHHEEEEHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCCCHHHCCCHHHHHHHH
AAESQVKVATSNFNRQQTLITSGFTTRATFDQAQETLRTAEGSLESAKAQLGTAKDALTY
HHCCEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHEE
TELRADADGTITARNIEVGQVAQAGQSVFTLAHDGNRDAVIDVYEAALSLKFDDSKVALA
EHEECCCCCEEEEECCCHHHHHHCCCEEEEEEECCCCCCEEEEEEEHEEEEECCCEEEEE
LLSDPSVTAKGTVREVSPTIDAKSGTVRIKIAIENPSPEMTLGSAVSATGFIKPEQRIVL
EECCCCCCCCCCEEECCCCEECCCCEEEEEEEEECCCCCEEECCCCCCCCCCCCCCEEEE
PWSALTAASKTPAVWLVNATDKTVSLKPIKIEDYETGTIVVSAGLEPGDRVVTDGGKLLS
EHHHHHCCCCCCEEEEEECCCCEEEEEEEEEECCCCCEEEEECCCCCCCEEEECCCCEEE
IGQQITFNEEKRS
ECCEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA