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The map label for this gene is mdtA [H]

Identifier: 146338794

GI number: 146338794

Start: 1848539

End: 1849615

Strand: Reverse

Name: mdtA [H]

Synonym: BRADO1728

Alternate gene names: 146338794

Gene position: 1849615-1848539 (Counterclockwise)

Preceding gene: 146338795

Following gene: 146338793

Centisome position: 24.81

GC content: 67.78

Gene sequence:

>1077_bases
GTGATGACGCCGATGCGTTGTGTTGTTTCGCTTGGTGCGCTCGCCGTGCTCGCCGGCTGCAACGAGAAGGCCGCGGCGCC
GGAGCCGGTCCGGCCGGTGCTGTCGCTGAAGGTCGAGCCGCAAGCCGCCAACGGATCCGCGGTCACCGGCACCATCGAGC
CGCGCTACAAGGCCGATCTCAGCTTTCGCGTGCTCGGCCGCCTGATCGCGCGCCCCGTCTATGTCGGCGACATGATCAGG
CAGGATCAGGTGGTGGCGGCGATCGATCCCGCCGCGCTCGAATTCGCGGTGCGCGCCTCCGCGGCCGAAGTGTCGCGCAG
CCAGGCGCAACTGACCAACGCAACCGGCACCGAAGGCCGCCAGCGCACTCTGCTGGAAACCGACGCCACGACAAAAGCGA
CATTGGAGAACGCCGAGCAGTCGCGCGCCGCCGCGCAGGCCTCGGTGATCAAGGCGCAGTCCAACCTCGCAAAGGCGCGC
GAGCAGCTCGGCTATGCGCAGCTGAAGGCCGATTTCGCCGGCATCGTCACCGCCGTCAACGCCGAGGTCGGCCAGGTCGT
GTCGCCCGGCCAGAGCGTGGTCACGGTGGCGCGGCCGGATATTCGCGAAGCCGTCATCGACGTCGGCGACGATATCGCAG
GTGGCCTGCAGGCCGGTACGTCGTTCACGGTGCGGTCGCAAGTCGATCCGAGCGTAAGCACGACCGGCACGGTGCGCGAG
ATCGCGCCGCGCGCCGACGCGACGACGCGGACCCGCCGTATCCGCATCACGCTCGACAATCCGCCTGACATCATGCGTCT
CGGGACCACCGTGACCGCCGCGCTCAACACCGAGCAGAAGACCATCATCAAGCTGCCGCGCTCGGCGATCCTCGCCGAGA
ACGACAAGAGCTTCGTCTGGCTCGTCGACGCCGCCAGCAAGACGGTCAAGCGACAGCAGATCACGATCGCGACCAACGAG
GACGGTGGCATCCGCGTCACCAGCGGTCTCGAAGCCGGGCAGCGTGTCGTCACCGCCGGCGTGAACAGTCTGAAGGATGG
CCAGGCCGTCCGCATCGATCAGGAAACTCAGCCGTGA

Upstream 100 bases:

>100_bases
TCGTTTCGGCCGGGCTTGAACCTGGCGACCGCGTCGTGACCGACGGCGGCAAGCTCTTGAGCATCGGCCAGCAGATCACG
TTCAACGAGGAGAAGCGGTC

Downstream 100 bases:

>100_bases
AGTCCTTCAATCTCTCCGACTGGGCGCTCGAGCACCGCTCGCTGGTCTGGTACTTCATGATCGCCTTCATGGCGGCGGGC
CTGTTCTCCTACCTCCATCT

Product: RND family mulitdrug efflux protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MMTPMRCVVSLGALAVLAGCNEKAAAPEPVRPVLSLKVEPQAANGSAVTGTIEPRYKADLSFRVLGRLIARPVYVGDMIR
QDQVVAAIDPAALEFAVRASAAEVSRSQAQLTNATGTEGRQRTLLETDATTKATLENAEQSRAAAQASVIKAQSNLAKAR
EQLGYAQLKADFAGIVTAVNAEVGQVVSPGQSVVTVARPDIREAVIDVGDDIAGGLQAGTSFTVRSQVDPSVSTTGTVRE
IAPRADATTRTRRIRITLDNPPDIMRLGTTVTAALNTEQKTIIKLPRSAILAENDKSFVWLVDAASKTVKRQQITIATNE
DGGIRVTSGLEAGQRVVTAGVNSLKDGQAVRIDQETQP

Sequences:

>Translated_358_residues
MMTPMRCVVSLGALAVLAGCNEKAAAPEPVRPVLSLKVEPQAANGSAVTGTIEPRYKADLSFRVLGRLIARPVYVGDMIR
QDQVVAAIDPAALEFAVRASAAEVSRSQAQLTNATGTEGRQRTLLETDATTKATLENAEQSRAAAQASVIKAQSNLAKAR
EQLGYAQLKADFAGIVTAVNAEVGQVVSPGQSVVTVARPDIREAVIDVGDDIAGGLQAGTSFTVRSQVDPSVSTTGTVRE
IAPRADATTRTRRIRITLDNPPDIMRLGTTVTAALNTEQKTIIKLPRSAILAENDKSFVWLVDAASKTVKRQQITIATNE
DGGIRVTSGLEAGQRVVTAGVNSLKDGQAVRIDQETQP
>Mature_358_residues
MMTPMRCVVSLGALAVLAGCNEKAAAPEPVRPVLSLKVEPQAANGSAVTGTIEPRYKADLSFRVLGRLIARPVYVGDMIR
QDQVVAAIDPAALEFAVRASAAEVSRSQAQLTNATGTEGRQRTLLETDATTKATLENAEQSRAAAQASVIKAQSNLAKAR
EQLGYAQLKADFAGIVTAVNAEVGQVVSPGQSVVTVARPDIREAVIDVGDDIAGGLQAGTSFTVRSQVDPSVSTTGTVRE
IAPRADATTRTRRIRITLDNPPDIMRLGTTVTAALNTEQKTIIKLPRSAILAENDKSFVWLVDAASKTVKRQQITIATNE
DGGIRVTSGLEAGQRVVTAGVNSLKDGQAVRIDQETQP

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=314, Percent_Identity=26.1146496815287, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789929, Length=357, Percent_Identity=26.0504201680672, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87081796, Length=335, Percent_Identity=25.6716417910448, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 37760; Mature: 37760

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTPMRCVVSLGALAVLAGCNEKAAAPEPVRPVLSLKVEPQAANGSAVTGTIEPRYKADL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCHHCCC
SFRVLGRLIARPVYVGDMIRQDQVVAAIDPAALEFAVRASAAEVSRSQAQLTNATGTEGR
HHHHHHHHHHCCHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QRTLLETDATTKATLENAEQSRAAAQASVIKAQSNLAKAREQLGYAQLKADFAGIVTAVN
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECC
AEVGQVVSPGQSVVTVARPDIREAVIDVGDDIAGGLQAGTSFTVRSQVDPSVSTTGTVRE
HHHCCCCCCCCCEEEEECCCHHHHHHHCCCCCCCCHHCCCEEEEECCCCCCCCCCCCHHH
IAPRADATTRTRRIRITLDNPPDIMRLGTTVTAALNTEQKTIIKLPRSAILAENDKSFVW
HCCCCCCCCCEEEEEEEECCCCCCEEECCEEEEEECCCCHHHHHCCCHHEEECCCCCEEE
LVDAASKTVKRQQITIATNEDGGIRVTSGLEAGQRVVTAGVNSLKDGQAVRIDQETQP
EEECCCHHHEEEEEEEEECCCCCEEEECCCCCCCEEEHHCCCCCCCCCEEEECCCCCC
>Mature Secondary Structure
MMTPMRCVVSLGALAVLAGCNEKAAAPEPVRPVLSLKVEPQAANGSAVTGTIEPRYKADL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCHHCCC
SFRVLGRLIARPVYVGDMIRQDQVVAAIDPAALEFAVRASAAEVSRSQAQLTNATGTEGR
HHHHHHHHHHCCHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QRTLLETDATTKATLENAEQSRAAAQASVIKAQSNLAKAREQLGYAQLKADFAGIVTAVN
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECC
AEVGQVVSPGQSVVTVARPDIREAVIDVGDDIAGGLQAGTSFTVRSQVDPSVSTTGTVRE
HHHCCCCCCCCCEEEEECCCHHHHHHHCCCCCCCCHHCCCEEEEECCCCCCCCCCCCHHH
IAPRADATTRTRRIRITLDNPPDIMRLGTTVTAALNTEQKTIIKLPRSAILAENDKSFVW
HCCCCCCCCCEEEEEEEECCCCCCEEECCEEEEEECCCCHHHHHCCCHHEEECCCCCEEE
LVDAASKTVKRQQITIATNEDGGIRVTSGLEAGQRVVTAGVNSLKDGQAVRIDQETQP
EEECCCHHHEEEEEEEEECCCCCEEEECCCCCCCEEEHHCCCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]