Click here to switch to the map view.

The map label for this gene is garD [H]

Identifier: 146338633

GI number: 146338633

Start: 1671424

End: 1672962

Strand: Reverse

Name: garD [H]

Synonym: BRADO1562

Alternate gene names: 146338633

Gene position: 1672962-1671424 (Counterclockwise)

Preceding gene: 146338634

Following gene: 146338632

Centisome position: 22.44

GC content: 66.86

Gene sequence:

>1539_bases
ATGAACCAGCAGGTCGTGAATCAGGAGCCGCGGATCATCAAGCTCAACGCGCGCGACAACGTCGCGATCGTGGTCAACGA
TTTCGGCCTGCCTGCCGGCACCAAGCTGCCCGACGGCCTGACGCTGAAGACCTTCGTCCCGCAGGGCCACAAGACCGCAC
TGGTCGACATCGCCGAGGGCGCGCCGATCATCCGCTACGGCGAGATCATCGGGTACGCGAAGTCGCTCATCGCCGCCGGC
GAGTGGGTCGACGAGGCCCGCATCGACATGCCTGAGGCGCCTGCGCTCGACCAGCTCGAAATCTCCACCGCCGTCCCGGC
ACCGCTGCCGCCGCTCGACGGCTACACGTTCGAAGGCTATCGCAACGCCGACGGCTCGGTCGGCACCCGCAACGTGCTGG
GCATCTCGACCTCGGTCCAGTGTGTGAAGGGGACGCTCGAATTCGCGATCAAGCGGATCAACAGCGAGCTCTTGCCGAAG
TACCCCAACGTCGACGACGTCGTTGCACTGACCCACGCCTATGGCTGCGGCGTCGCGATCACGGCGCCCGACGCGGTGGT
GCCGATCCGCACCTTGCAGAACCTCGCACTCAACCCGAATTTCGGCGGCGAGATCCTGGTCGTCGGCCTCGGCTGCGAGA
AGCTCGCGCCGGAGCGGCTGCTGCCGGAAGGCACTGAAGACTCGATCGTGCGCATGCAGGACGAGGCCTTCGACGGCTTC
GGCGCCATCGTCGACGCCATCATGACCCAGGCCGATAGACGCCTTGCCGAACTCAACAAGCGCACGCGTCAGACCTGCCC
GGCCTCCGATCTCGTCATCGGCCTGCAATGCGGCGGCAGCGACGCGTTCTCCGGCGTCACCGCCAATCCGGCGGTCGGCT
TCGCCGCGGATCTGTTGGTGCGCGCCGGCGCCACCGTGATGTTCTCGGAAGTCACTGAAGTCCGCGACGCCATCCAGCTT
TTGACTCGCCGCGCCATCAACGAGGAGGTCGGCCGCGCGCTGATCCGCGAGATGGACTGGTATGACGCTTATCTCAAGCG
CGGCGGCGCCGATCGCAGCGCCAACACCACGCCCGGCAACAAGAAGGGCGGCCTCGCCAACATCGTCGAAAAGTCGCTCG
GCTCGATCGTGAAGTCGGGCTCGGGCCCGATCCATGGCGTGCTGGCGCCGGGCGAGAAGGCCAAGCAGAAGGGCATGCTG
TTCGCGGCAACGCCGGCCTCCGACTTCATCTGCGGCACCTTGCAGCTCGCCTCCGGCATGACCTTGCAGGTGTTCACCAC
CGGCCGCGGCACGCCCTACGGCCTCGCGGCCGCGCCCGTCATCAAGGTCGCCACCCGCACCGAGCTGGCGCGGCGCTGGA
AGGACCTGATCGACTTCGACGCCGGCCGCATCGCCACCGGCGAGATGACGATCGAGGAGACCGGCTGGGAGCTGTTCAAG
CTGATCCTCGATGTCGCGAGCGGCCGTACCAAGCCGTGGTCGGACCGGTGGGGCATTCACAACGACCTGACGCTGTTCAA
TCCCGCGCCGGTGACTTGA

Upstream 100 bases:

>100_bases
GCGCCGTGCCCACCGACGGTCGACCAAGACGCTAGACGGTGGGCACGCTTCGCTTTGCCCACCCTACGGACTACGAAGCC
GAACGCGAAACGGAGCCAGC

Downstream 100 bases:

>100_bases
GGAGGAGCTCGCTCACCCCGCCATGTTCGTTACGTCACGCAGACCCATCCCCGTCATTGCGAGCGAAGCGAAGCAATCCA
GAGGCCCGTCCACCATCCTG

Product: (D)-galactarate dehydrogenase

Products: NA

Alternate protein names: GalcD [H]

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MNQQVVNQEPRIIKLNARDNVAIVVNDFGLPAGTKLPDGLTLKTFVPQGHKTALVDIAEGAPIIRYGEIIGYAKSLIAAG
EWVDEARIDMPEAPALDQLEISTAVPAPLPPLDGYTFEGYRNADGSVGTRNVLGISTSVQCVKGTLEFAIKRINSELLPK
YPNVDDVVALTHAYGCGVAITAPDAVVPIRTLQNLALNPNFGGEILVVGLGCEKLAPERLLPEGTEDSIVRMQDEAFDGF
GAIVDAIMTQADRRLAELNKRTRQTCPASDLVIGLQCGGSDAFSGVTANPAVGFAADLLVRAGATVMFSEVTEVRDAIQL
LTRRAINEEVGRALIREMDWYDAYLKRGGADRSANTTPGNKKGGLANIVEKSLGSIVKSGSGPIHGVLAPGEKAKQKGML
FAATPASDFICGTLQLASGMTLQVFTTGRGTPYGLAAAPVIKVATRTELARRWKDLIDFDAGRIATGEMTIEETGWELFK
LILDVASGRTKPWSDRWGIHNDLTLFNPAPVT

Sequences:

>Translated_512_residues
MNQQVVNQEPRIIKLNARDNVAIVVNDFGLPAGTKLPDGLTLKTFVPQGHKTALVDIAEGAPIIRYGEIIGYAKSLIAAG
EWVDEARIDMPEAPALDQLEISTAVPAPLPPLDGYTFEGYRNADGSVGTRNVLGISTSVQCVKGTLEFAIKRINSELLPK
YPNVDDVVALTHAYGCGVAITAPDAVVPIRTLQNLALNPNFGGEILVVGLGCEKLAPERLLPEGTEDSIVRMQDEAFDGF
GAIVDAIMTQADRRLAELNKRTRQTCPASDLVIGLQCGGSDAFSGVTANPAVGFAADLLVRAGATVMFSEVTEVRDAIQL
LTRRAINEEVGRALIREMDWYDAYLKRGGADRSANTTPGNKKGGLANIVEKSLGSIVKSGSGPIHGVLAPGEKAKQKGML
FAATPASDFICGTLQLASGMTLQVFTTGRGTPYGLAAAPVIKVATRTELARRWKDLIDFDAGRIATGEMTIEETGWELFK
LILDVASGRTKPWSDRWGIHNDLTLFNPAPVT
>Mature_512_residues
MNQQVVNQEPRIIKLNARDNVAIVVNDFGLPAGTKLPDGLTLKTFVPQGHKTALVDIAEGAPIIRYGEIIGYAKSLIAAG
EWVDEARIDMPEAPALDQLEISTAVPAPLPPLDGYTFEGYRNADGSVGTRNVLGISTSVQCVKGTLEFAIKRINSELLPK
YPNVDDVVALTHAYGCGVAITAPDAVVPIRTLQNLALNPNFGGEILVVGLGCEKLAPERLLPEGTEDSIVRMQDEAFDGF
GAIVDAIMTQADRRLAELNKRTRQTCPASDLVIGLQCGGSDAFSGVTANPAVGFAADLLVRAGATVMFSEVTEVRDAIQL
LTRRAINEEVGRALIREMDWYDAYLKRGGADRSANTTPGNKKGGLANIVEKSLGSIVKSGSGPIHGVLAPGEKAKQKGML
FAATPASDFICGTLQLASGMTLQVFTTGRGTPYGLAAAPVIKVATRTELARRWKDLIDFDAGRIATGEMTIEETGWELFK
LILDVASGRTKPWSDRWGIHNDLTLFNPAPVT

Specific function: D-galactarate metabolism; first step. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789516, Length=509, Percent_Identity=66.4047151277014, Blast_Score=709, Evalue=0.0,
Organism=Escherichia coli, GI1789475, Length=495, Percent_Identity=33.9393939393939, Blast_Score=229, Evalue=3e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR017654
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.42 [H]

Molecular weight: Translated: 54661; Mature: 54661

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQVVNQEPRIIKLNARDNVAIVVNDFGLPAGTKLPDGLTLKTFVPQGHKTALVDIAEG
CCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCC
APIIRYGEIIGYAKSLIAAGEWVDEARIDMPEAPALDQLEISTAVPAPLPPLDGYTFEGY
CCEEEHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCEEECCC
RNADGSVGTRNVLGISTSVQCVKGTLEFAIKRINSELLPKYPNVDDVVALTHAYGCGVAI
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEE
TAPDAVVPIRTLQNLALNPNFGGEILVVGLGCEKLAPERLLPEGTEDSIVRMQDEAFDGF
ECCCCEEHHHHHHHCCCCCCCCCEEEEEEECHHHCCCHHCCCCCCCCCEEEEHHHHCCHH
GAIVDAIMTQADRRLAELNKRTRQTCPASDLVIGLQCGGSDAFSGVTANPAVGFAADLLV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
RAGATVMFSEVTEVRDAIQLLTRRAINEEVGRALIREMDWYDAYLKRGGADRSANTTPGN
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
KKGGLANIVEKSLGSIVKSGSGPIHGVLAPGEKAKQKGMLFAATPASDFICGTLQLASGM
CCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCEEEEECCCCCHHEEHHHHCCCC
TLQVFTTGRGTPYGLAAAPVIKVATRTELARRWKDLIDFDAGRIATGEMTIEETGWELFK
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCEEEHHHHHHHHH
LILDVASGRTKPWSDRWGIHNDLTLFNPAPVT
HHHHHHCCCCCCCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MNQQVVNQEPRIIKLNARDNVAIVVNDFGLPAGTKLPDGLTLKTFVPQGHKTALVDIAEG
CCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCC
APIIRYGEIIGYAKSLIAAGEWVDEARIDMPEAPALDQLEISTAVPAPLPPLDGYTFEGY
CCEEEHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCEEECCC
RNADGSVGTRNVLGISTSVQCVKGTLEFAIKRINSELLPKYPNVDDVVALTHAYGCGVAI
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEE
TAPDAVVPIRTLQNLALNPNFGGEILVVGLGCEKLAPERLLPEGTEDSIVRMQDEAFDGF
ECCCCEEHHHHHHHCCCCCCCCCEEEEEEECHHHCCCHHCCCCCCCCCEEEEHHHHCCHH
GAIVDAIMTQADRRLAELNKRTRQTCPASDLVIGLQCGGSDAFSGVTANPAVGFAADLLV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
RAGATVMFSEVTEVRDAIQLLTRRAINEEVGRALIREMDWYDAYLKRGGADRSANTTPGN
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
KKGGLANIVEKSLGSIVKSGSGPIHGVLAPGEKAKQKGMLFAATPASDFICGTLQLASGM
CCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCEEEEECCCCCHHEEHHHHCCCC
TLQVFTTGRGTPYGLAAAPVIKVATRTELARRWKDLIDFDAGRIATGEMTIEETGWELFK
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCEEEHHHHHHHHH
LILDVASGRTKPWSDRWGIHNDLTLFNPAPVT
HHHHHHCCCCCCCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]