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The map label for this gene is dinB [H]

Identifier: 146338544

GI number: 146338544

Start: 1569961

End: 1571067

Strand: Reverse

Name: dinB [H]

Synonym: BRADO1464

Alternate gene names: 146338544

Gene position: 1571067-1569961 (Counterclockwise)

Preceding gene: 146338548

Following gene: 146338542

Centisome position: 21.07

GC content: 65.13

Gene sequence:

>1107_bases
ATGCCAAGCTCCGGTCCGGACCCGGATGCCGCGCCGACGGCCATCCGCAAGATCATCCACATCGACATGGATGCATTCTA
TGCGTCGGTCGAGCAGCGGGACAATCCCGAGCTGCGCGGCAGGCCCGTGGCCGTCGGCGGCTCACGCGAGCGCGGCGTGG
TGGCGGCCGCGAGCTATGAGGCGCGCAAGTTCGGCGTGCGCTCGGCGATGCCGTCGATGACCGCCAAGCGGCTCTGTCCC
GACCTGATCTTCGTCAAGCCGCGATTCGAGGTCTACAAGGCGATCAGCCAGCAGATTCGCGCGATCTTCGCCGAGCACAC
GCCGATCATCGAGCCGCTGTCGCTCGACGAAGCCTATCTCGACGTCACCGACAATCTGCAGGGCATCCCGCTCGCCCGCG
ACATTGCCTTGCAGATCCGCGCCAGGATCAAGGCGGAGACCGGCCTCAACGCTTCCGCCGGGATCTCCTACAACAAATTC
CTGGCAAAGCTCGCCTCGGATCATCGCAAGCCGAACGGCCAATATGTGATCTCTCCGGAGACGGGCGCGGCGTTCGTCGA
GGGGCTGCCGGTCGGCAGGTTTCACGGCATCGGCCCGGCAACCGCCGCCAAGTTCAATGCGCTCGGAATTCACACCGGCC
TCGACATCCGCAATCAGACCTTGCCGTTCCTGCAGCAGCACTTCGGAAAGGCAGGCAGCTACTATTATTGGATCTCGCGC
GGGATCGATCATCGCCCGGTCAGGGCCAACCGCATCCGCAAATCGATCGGCGCGGAGAACACGTTCGCCACCGACCTGAT
CGAGTTCGAGCCGATGGCGGCCGAGTTGCAGCCCCTGATCGACAAGGTCTGGCGCCACTGTGACGCGACCGGCAACAGAG
GGCGAACGGTCACGTTGAAGGTCAAGTTCGCCGACTTCGACGTCATCACGCGCAGCAGGTCCGTTGCGACGGCGGTCTCC
AGCCGCGCGGAACTCGAGCGCCTGTCGCTGGCGCTGCTTCAGGCCGAGCTGCCGTTGCCCAAGCCGGTACGTCTGCTCGG
CGTCTCGCTGTCATCGCTGCAGGAGGCGGAGGCGGTCGTCGAGACGCAGCTGGCCATGCCGATCTGA

Upstream 100 bases:

>100_bases
TCAAGGCCGGGACGACGGCGGAGCTTGGAGCGGCCGCACCGGCAAAGCCGAACAAGCCCTGCTGACAGACTTTGGCGCCT
GGCTCTGATACATCTCTCTC

Downstream 100 bases:

>100_bases
GCCGCGATTGGCGGAGCAAAAAGCGCCTGCGCGGTGACGGCGTCGCGCGCAAGCGATCGCTAGTTCCTCATCAGCAAATC
GAACCGCCGCCGATCAACCG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 2 [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MPSSGPDPDAAPTAIRKIIHIDMDAFYASVEQRDNPELRGRPVAVGGSRERGVVAAASYEARKFGVRSAMPSMTAKRLCP
DLIFVKPRFEVYKAISQQIRAIFAEHTPIIEPLSLDEAYLDVTDNLQGIPLARDIALQIRARIKAETGLNASAGISYNKF
LAKLASDHRKPNGQYVISPETGAAFVEGLPVGRFHGIGPATAAKFNALGIHTGLDIRNQTLPFLQQHFGKAGSYYYWISR
GIDHRPVRANRIRKSIGAENTFATDLIEFEPMAAELQPLIDKVWRHCDATGNRGRTVTLKVKFADFDVITRSRSVATAVS
SRAELERLSLALLQAELPLPKPVRLLGVSLSSLQEAEAVVETQLAMPI

Sequences:

>Translated_368_residues
MPSSGPDPDAAPTAIRKIIHIDMDAFYASVEQRDNPELRGRPVAVGGSRERGVVAAASYEARKFGVRSAMPSMTAKRLCP
DLIFVKPRFEVYKAISQQIRAIFAEHTPIIEPLSLDEAYLDVTDNLQGIPLARDIALQIRARIKAETGLNASAGISYNKF
LAKLASDHRKPNGQYVISPETGAAFVEGLPVGRFHGIGPATAAKFNALGIHTGLDIRNQTLPFLQQHFGKAGSYYYWISR
GIDHRPVRANRIRKSIGAENTFATDLIEFEPMAAELQPLIDKVWRHCDATGNRGRTVTLKVKFADFDVITRSRSVATAVS
SRAELERLSLALLQAELPLPKPVRLLGVSLSSLQEAEAVVETQLAMPI
>Mature_367_residues
PSSGPDPDAAPTAIRKIIHIDMDAFYASVEQRDNPELRGRPVAVGGSRERGVVAAASYEARKFGVRSAMPSMTAKRLCPD
LIFVKPRFEVYKAISQQIRAIFAEHTPIIEPLSLDEAYLDVTDNLQGIPLARDIALQIRARIKAETGLNASAGISYNKFL
AKLASDHRKPNGQYVISPETGAAFVEGLPVGRFHGIGPATAAKFNALGIHTGLDIRNQTLPFLQQHFGKAGSYYYWISRG
IDHRPVRANRIRKSIGAENTFATDLIEFEPMAAELQPLIDKVWRHCDATGNRGRTVTLKVKFADFDVITRSRSVATAVSS
RAELERLSLALLQAELPLPKPVRLLGVSLSSLQEAEAVVETQLAMPI

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=338, Percent_Identity=33.1360946745562, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI7706681, Length=339, Percent_Identity=33.0383480825959, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI5729982, Length=320, Percent_Identity=32.8125, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI7705344, Length=110, Percent_Identity=52.7272727272727, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI154350220, Length=334, Percent_Identity=29.0419161676647, Blast_Score=132, Evalue=4e-31,
Organism=Escherichia coli, GI1786425, Length=304, Percent_Identity=46.7105263157895, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1787432, Length=221, Percent_Identity=33.0316742081448, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI193205700, Length=400, Percent_Identity=31, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI193205702, Length=222, Percent_Identity=35.1351351351351, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17537959, Length=254, Percent_Identity=28.3464566929134, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI115534089, Length=122, Percent_Identity=39.344262295082, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19923006, Length=420, Percent_Identity=27.6190476190476, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=29.6819787985866, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=29.6819787985866, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24668444, Length=243, Percent_Identity=31.2757201646091, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40332; Mature: 40201

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSGPDPDAAPTAIRKIIHIDMDAFYASVEQRDNPELRGRPVAVGGSRERGVVAAASYE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEECCH
ARKFGVRSAMPSMTAKRLCPDLIFVKPRFEVYKAISQQIRAIFAEHTPIIEPLSLDEAYL
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHE
DVTDNLQGIPLARDIALQIRARIKAETGLNASAGISYNKFLAKLASDHRKPNGQYVISPE
ECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCC
TGAAFVEGLPVGRFHGIGPATAAKFNALGIHTGLDIRNQTLPFLQQHFGKAGSYYYWISR
CCCHHHHCCCCCCCCCCCCHHHHHCCEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEEC
GIDHRPVRANRIRKSIGAENTFATDLIEFEPMAAELQPLIDKVWRHCDATGNRGRTVTLK
CCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
VKFADFDVITRSRSVATAVSSRAELERLSLALLQAELPLPKPVRLLGVSLSSLQEAEAVV
EEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHH
ETQLAMPI
HHHHCCCC
>Mature Secondary Structure 
PSSGPDPDAAPTAIRKIIHIDMDAFYASVEQRDNPELRGRPVAVGGSRERGVVAAASYE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEECCH
ARKFGVRSAMPSMTAKRLCPDLIFVKPRFEVYKAISQQIRAIFAEHTPIIEPLSLDEAYL
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHE
DVTDNLQGIPLARDIALQIRARIKAETGLNASAGISYNKFLAKLASDHRKPNGQYVISPE
ECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCC
TGAAFVEGLPVGRFHGIGPATAAKFNALGIHTGLDIRNQTLPFLQQHFGKAGSYYYWISR
CCCHHHHCCCCCCCCCCCCHHHHHCCEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEEC
GIDHRPVRANRIRKSIGAENTFATDLIEFEPMAAELQPLIDKVWRHCDATGNRGRTVTLK
CCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
VKFADFDVITRSRSVATAVSSRAELERLSLALLQAELPLPKPVRLLGVSLSSLQEAEAVV
EEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHH
ETQLAMPI
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]