Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 146338495

GI number: 146338495

Start: 1512651

End: 1513358

Strand: Reverse

Name: ompR [H]

Synonym: BRADO1413

Alternate gene names: 146338495

Gene position: 1513358-1512651 (Counterclockwise)

Preceding gene: 146338500

Following gene: 146338494

Centisome position: 20.3

GC content: 67.23

Gene sequence:

>708_bases
ATGGACAGCCGACCCCACCTCCTGATCATCGAAGACGACATCGAGATCCGCAGCCTGCTGCGCGACCATCTCGCCCGCGA
GGGTTTTCGCGTCGATGTCGGCGACGGTGGCGCAGCCCTCGACCGTTTTCGCAACACTTTCGGCGATCCCGACCTCGTTG
TGCTCGACATCATGCTGCCCGGCGAGGATGGGTTGTCGATCTGCCGTCGGCTGCGCGCGGCGTCGCGGGTGCCGATCCTG
ATGCTGACGGCCAAGGGCGACGAGATCGACCGCATCGTCGGGCTCGAGATGGGCGCCGACGACTATCTGCCAAAGCCGTT
CAGCCCGCGCGAGCTGGTGGCGCGGATTCGCGCCATCCTGCGCCGTGCCGAGCCGGCGCCGCTGGAGAACCGCCGCTTTC
TCGTCAATGCCACGCTCACCGTCGATCTCGACAAGCGCGAGATCGCGCATGCGCAGGACGGGGCGCTGCCGCTGACCAGC
GCCGAGTTCGAGCTGCTCGGCTGCTTCCTGGTCAGGCCCAACCGCGTGCTGTCGCGCGATCAGCTGATGGATTGGACGCG
CGGCCGGCAGGCCGATCCGCTCGACCGCACCATCGACGTGCAAGTGAGCCGGCTGCGCAAGAAGATCGAGCGCGACGGCG
AGGAGGAGCTGATCAAGACGGTGCGCAGCGCCGGCTACATCTTCACCGGCTCGGTCAAGGAGCTGTGA

Upstream 100 bases:

>100_bases
GTTTGCGGGCGGTTTGCAGGACAGAGCCGCCATGTAACGTTTTGTAACGGTGTCCAGGCCCGGGTTGCCCGGCGCGGCCG
GGTGTTCTTAAAACCATCGC

Downstream 100 bases:

>100_bases
AACGTGCTCGGGCGTCTCGGCTTCGCCGGCCGGCTGATGGCGATCGTGCTGTTCGCGCTGATCGCGCTATGGGCGGCCGG
CGTCGGCTGGCTGTTCCTGA

Product: OmpR family two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MDSRPHLLIIEDDIEIRSLLRDHLAREGFRVDVGDGGAALDRFRNTFGDPDLVVLDIMLPGEDGLSICRRLRAASRVPIL
MLTAKGDEIDRIVGLEMGADDYLPKPFSPRELVARIRAILRRAEPAPLENRRFLVNATLTVDLDKREIAHAQDGALPLTS
AEFELLGCFLVRPNRVLSRDQLMDWTRGRQADPLDRTIDVQVSRLRKKIERDGEEELIKTVRSAGYIFTGSVKEL

Sequences:

>Translated_235_residues
MDSRPHLLIIEDDIEIRSLLRDHLAREGFRVDVGDGGAALDRFRNTFGDPDLVVLDIMLPGEDGLSICRRLRAASRVPIL
MLTAKGDEIDRIVGLEMGADDYLPKPFSPRELVARIRAILRRAEPAPLENRRFLVNATLTVDLDKREIAHAQDGALPLTS
AEFELLGCFLVRPNRVLSRDQLMDWTRGRQADPLDRTIDVQVSRLRKKIERDGEEELIKTVRSAGYIFTGSVKEL
>Mature_235_residues
MDSRPHLLIIEDDIEIRSLLRDHLAREGFRVDVGDGGAALDRFRNTFGDPDLVVLDIMLPGEDGLSICRRLRAASRVPIL
MLTAKGDEIDRIVGLEMGADDYLPKPFSPRELVARIRAILRRAEPAPLENRRFLVNATLTVDLDKREIAHAQDGALPLTS
AEFELLGCFLVRPNRVLSRDQLMDWTRGRQADPLDRTIDVQVSRLRKKIERDGEEELIKTVRSAGYIFTGSVKEL

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=46.8354430379747, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=39.647577092511, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=41.8502202643172, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI1790863, Length=239, Percent_Identity=34.7280334728033, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=43.9461883408072, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=39.9141630901288, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=37.8723404255319, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI145693140, Length=240, Percent_Identity=39.5833333333333, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1790860, Length=235, Percent_Identity=38.2978723404255, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI87082012, Length=232, Percent_Identity=35.3448275862069, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=34.5291479820628, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1786911, Length=211, Percent_Identity=38.3886255924171, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=33.1858407079646, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=34.375, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788550, Length=114, Percent_Identity=31.5789473684211, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI1790299, Length=121, Percent_Identity=33.0578512396694, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26548; Mature: 26548

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSRPHLLIIEDDIEIRSLLRDHLAREGFRVDVGDGGAALDRFRNTFGDPDLVVLDIMLP
CCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCEEEEEEEEC
GEDGLSICRRLRAASRVPILMLTAKGDEIDRIVGLEMGADDYLPKPFSPRELVARIRAIL
CCCHHHHHHHHHHHCCCCEEEEEECCCCCHHEEEEECCCCCCCCCCCCHHHHHHHHHHHH
RRAEPAPLENRRFLVNATLTVDLDKREIAHAQDGALPLTSAEFELLGCFLVRPNRVLSRD
HHCCCCCCCCCEEEEEEEEEEECCHHHHHHCCCCCCCCCCCCCEEEEEEEECCCHHHHHH
QLMDWTRGRQADPLDRTIDVQVSRLRKKIERDGEEELIKTVRSAGYIFTGSVKEL
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEECCCCCC
>Mature Secondary Structure
MDSRPHLLIIEDDIEIRSLLRDHLAREGFRVDVGDGGAALDRFRNTFGDPDLVVLDIMLP
CCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCCEEEEEEEEC
GEDGLSICRRLRAASRVPILMLTAKGDEIDRIVGLEMGADDYLPKPFSPRELVARIRAIL
CCCHHHHHHHHHHHCCCCEEEEEECCCCCHHEEEEECCCCCCCCCCCCHHHHHHHHHHHH
RRAEPAPLENRRFLVNATLTVDLDKREIAHAQDGALPLTSAEFELLGCFLVRPNRVLSRD
HHCCCCCCCCCEEEEEEEEEEECCHHHHHHCCCCCCCCCCCCCEEEEEEEECCCHHHHHH
QLMDWTRGRQADPLDRTIDVQVSRLRKKIERDGEEELIKTVRSAGYIFTGSVKEL
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]