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The map label for this gene is dapE [H]

Identifier: 146337889

GI number: 146337889

Start: 819889

End: 821043

Strand: Reverse

Name: dapE [H]

Synonym: BRADO0774

Alternate gene names: 146337889

Gene position: 821043-819889 (Counterclockwise)

Preceding gene: 146337890

Following gene: 146337884

Centisome position: 11.01

GC content: 65.97

Gene sequence:

>1155_bases
ATGACCGATGCCCTCACCATCACCCGCGACCTGATCCGCTGCCCCTCCGTCACCCCCGCCGACGCCGGCGCGCTCGGCGT
GCTCGAAGCCCTGCTGAAACAGGCGGGCTTCACGACCCATCGCGTGACGTTCTCGGAACCCGGCACCGCGGACATCGACA
ACCTTTATGCACGCATCGGGACCGAGGGGCCGCACATCACCTTCGCGGGCCACACCGACGTGGTGCCGCCGGGCGACGAA
GCCTCCTGGAGCCTGCCGGCATTCTCCGGCGAGGTGAAAGACGGCTACATCTATGGCCGCGGCGCGGTCGACATGAAGGG
CGGCATCGCCTGCAGCGTCGCCGCGGCGCTGGACTATCTCCGCGACCATGGTAGCCAGCCGAAGGGCTCGATCTCGTTCC
TCATCACCGGCGACGAGGAGGACGTCTCGATCAACGGCACCATCAAACTACTGCAATGGGCCGCCGATCGCGGGGAGACA
TTCGATCATTGCGTGCTGGGTGAGCCGTCCAATCAGGAGGTCATGGGCGACTGCATCAAGATCGGCCGTCGCGGCTCGCA
GTCGGGCACATTGATCGTCGAGGGCAAGCAGGGCCACGTCGCCTACCCGCACCGCGCCTCCAACCCGGTGCCGGACATCT
CGCGGCTGATCGTGGCCTTGTCGGACGAGCCGCTCGACAATGGCAGCGCGCAATTCCAGCCGTCCAATCTCGAATTCACC
ACCGTCGACGTCGGCAACACCGCGACCAACGTCATCGCCGGCATCGCGCGGGCGAAGTTCAACATCCGCTACAACGACTG
CCATACCCAGGAGTCGCTGCGCGCGCTGGTCGAGCAGCGCCTGGCAAAAGCCTGCGGCAACCGCATCCGCGCCCATATCG
ACTGGCTGCCGTCGAACTCCGACGTGTTCCTGACCAAGCCCGGCCCGTTCACCGATCTCGCCGTCGCCGCCATCGAAGAG
GTCACGGGCCGCAAGCCGGAGCTGTCGACCACCGGCGGCACCTCGGACGCGCGTTTCATCTCGTCCTATTGTCCGGTGAT
CGAGTTCGGCCTGGTCGGCCAGACCATGCATCAGATCGACGAGCGCGCCTCCGTGGCGGACATCGCGACCTTGACGAAGA
TCTACCGCGGCATCCTCGATCGCTACTTCGCGTGA

Upstream 100 bases:

>100_bases
CCGCTCCAAGACCTCGATCAACGAGCTGCTGCGCGACTGATCATCCGGCGTCGGGCGGCCGCACTAGCGGCCGCCCGAAC
GCCCATGGTAAGCGGGGGGC

Downstream 100 bases:

>100_bases
GCGGCGCGCCTGATCGGGATCAGGCGGCTTTCACCTCCGCCAAGAACTGATCGACCTCGCGGCGCAGATCCGTCGCCTGC
CCTGCGAGGCTCGCGGCGGA

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MTDALTITRDLIRCPSVTPADAGALGVLEALLKQAGFTTHRVTFSEPGTADIDNLYARIGTEGPHITFAGHTDVVPPGDE
ASWSLPAFSGEVKDGYIYGRGAVDMKGGIACSVAAALDYLRDHGSQPKGSISFLITGDEEDVSINGTIKLLQWAADRGET
FDHCVLGEPSNQEVMGDCIKIGRRGSQSGTLIVEGKQGHVAYPHRASNPVPDISRLIVALSDEPLDNGSAQFQPSNLEFT
TVDVGNTATNVIAGIARAKFNIRYNDCHTQESLRALVEQRLAKACGNRIRAHIDWLPSNSDVFLTKPGPFTDLAVAAIEE
VTGRKPELSTTGGTSDARFISSYCPVIEFGLVGQTMHQIDERASVADIATLTKIYRGILDRYFA

Sequences:

>Translated_384_residues
MTDALTITRDLIRCPSVTPADAGALGVLEALLKQAGFTTHRVTFSEPGTADIDNLYARIGTEGPHITFAGHTDVVPPGDE
ASWSLPAFSGEVKDGYIYGRGAVDMKGGIACSVAAALDYLRDHGSQPKGSISFLITGDEEDVSINGTIKLLQWAADRGET
FDHCVLGEPSNQEVMGDCIKIGRRGSQSGTLIVEGKQGHVAYPHRASNPVPDISRLIVALSDEPLDNGSAQFQPSNLEFT
TVDVGNTATNVIAGIARAKFNIRYNDCHTQESLRALVEQRLAKACGNRIRAHIDWLPSNSDVFLTKPGPFTDLAVAAIEE
VTGRKPELSTTGGTSDARFISSYCPVIEFGLVGQTMHQIDERASVADIATLTKIYRGILDRYFA
>Mature_383_residues
TDALTITRDLIRCPSVTPADAGALGVLEALLKQAGFTTHRVTFSEPGTADIDNLYARIGTEGPHITFAGHTDVVPPGDEA
SWSLPAFSGEVKDGYIYGRGAVDMKGGIACSVAAALDYLRDHGSQPKGSISFLITGDEEDVSINGTIKLLQWAADRGETF
DHCVLGEPSNQEVMGDCIKIGRRGSQSGTLIVEGKQGHVAYPHRASNPVPDISRLIVALSDEPLDNGSAQFQPSNLEFTT
VDVGNTATNVIAGIARAKFNIRYNDCHTQESLRALVEQRLAKACGNRIRAHIDWLPSNSDVFLTKPGPFTDLAVAAIEEV
TGRKPELSTTGGTSDARFISSYCPVIEFGLVGQTMHQIDERASVADIATLTKIYRGILDRYFA

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=381, Percent_Identity=40.4199475065617, Blast_Score=274, Evalue=8e-75,
Organism=Escherichia coli, GI1790395, Length=375, Percent_Identity=26.9333333333333, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 41192; Mature: 41060

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDALTITRDLIRCPSVTPADAGALGVLEALLKQAGFTTHRVTFSEPGTADIDNLYARIG
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHC
TEGPHITFAGHTDVVPPGDEASWSLPAFSGEVKDGYIYGRGAVDMKGGIACSVAAALDYL
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEECCCCEEHHHHHHHHHH
RDHGSQPKGSISFLITGDEEDVSINGTIKLLQWAADRGETFDHCVLGEPSNQEVMGDCIK
HHCCCCCCCCEEEEEECCCCCEEECCEEEEEEEHHCCCCCCCEEECCCCCCHHHHHHHHH
IGRRGSQSGTLIVEGKQGHVAYPHRASNPVPDISRLIVALSDEPLDNGSAQFQPSNLEFT
HCCCCCCCCEEEEECCCCCEECCCCCCCCCCHHHHHEEEECCCCCCCCCCEECCCCCEEE
TVDVGNTATNVIAGIARAKFNIRYNDCHTQESLRALVEQRLAKACGNRIRAHIDWLPSNS
EEECCCHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHCHHEEEEEEECCCCC
DVFLTKPGPFTDLAVAAIEEVTGRKPELSTTGGTSDARFISSYCPVIEFGLVGQTMHQID
CEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
ERASVADIATLTKIYRGILDRYFA
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDALTITRDLIRCPSVTPADAGALGVLEALLKQAGFTTHRVTFSEPGTADIDNLYARIG
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHC
TEGPHITFAGHTDVVPPGDEASWSLPAFSGEVKDGYIYGRGAVDMKGGIACSVAAALDYL
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEECCCCEEHHHHHHHHHH
RDHGSQPKGSISFLITGDEEDVSINGTIKLLQWAADRGETFDHCVLGEPSNQEVMGDCIK
HHCCCCCCCCEEEEEECCCCCEEECCEEEEEEEHHCCCCCCCEEECCCCCCHHHHHHHHH
IGRRGSQSGTLIVEGKQGHVAYPHRASNPVPDISRLIVALSDEPLDNGSAQFQPSNLEFT
HCCCCCCCCEEEEECCCCCEECCCCCCCCCCHHHHHEEEECCCCCCCCCCEECCCCCEEE
TVDVGNTATNVIAGIARAKFNIRYNDCHTQESLRALVEQRLAKACGNRIRAHIDWLPSNS
EEECCCHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHCHHEEEEEEECCCCC
DVFLTKPGPFTDLAVAAIEEVTGRKPELSTTGGTSDARFISSYCPVIEFGLVGQTMHQID
CEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHH
ERASVADIATLTKIYRGILDRYFA
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA