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The map label for this gene is gcd [H]

Identifier: 146337729

GI number: 146337729

Start: 620993

End: 623392

Strand: Reverse

Name: gcd [H]

Synonym: BRADO0601

Alternate gene names: 146337729

Gene position: 623392-620993 (Counterclockwise)

Preceding gene: 146337731

Following gene: 146337728

Centisome position: 8.36

GC content: 68.0

Gene sequence:

>2400_bases
ATGGCCGCAGCCCGCCATCTGCAGCGCGCGCCGCTGCTGACCTTCACGGCCGTCATCGTCGGACTGATGGGCGTCGCACT
GCTCGCCGGCGGCTTCTGGCTCGCCGCGATCGGCGGCTCGCTGTACTACGTGATTGCCGGTGCGGCACTGCTCGGCACGG
CGTGGCTGCTGTGGCAGCGGCGCGCTTCCGCGCTATGGCTCTACGCGGCACTGCTGCTGGGCACGATGATCTGGGCGGTC
TGGGAGGTCGGGCTGGACTTCTGGTCGCTGGCGCCACGCGGCGACGTGCTGGCACCGCTCGGCGTCTGGCTGCTGCTGCC
GTTCATCACCGCGCATCTGGCCGGTGACATGCGCTCGGCGCGCTGGGGCCTTCTCGCCGTGCTCGCCGTCGCGGTGGTCG
TGCTCGGCGCCTCCCTGCGCGGCGACCGCTTCGGCGTCAACGGCGCGCTGCCGCAGGCCGCGGCTGCCACCGCCGGCACC
GATCCCGGGCCCGCGGAAGCGCAGGCCGACTGGACCGCGTATGGCGCCAGCAATTTCGGCACGCGCTTCTCGAGCCTGAA
GCAGATCACCGCCAATAATGTGAAGAACCTGCAACTCGCCTGGGAATTCCAGACCGGCGACCGCAAGGGGCCCGACGATC
CCGACGAGTTCACCAATGAGGTGACGCCGCTGAAGATCGGCGATCTGCTCTACACCTGCTCGCCGCACCAGATCGTGTTC
GCGCTCGATGCGGCCACGGGCAAGCAGCGCTGGACGTTCGATCCGAAGATCGAGCACCACAAGAATTTCCAGCACATGAC
CTGCCGCGGCGTCGCGTATCACGAGACCAAGCCCGGCGCAGTCGACGTGTCGGGCGCCGCGGCTCCGGGCGAATGCGCCA
GGCGCATCTTCCTGCCGACCGACGACGGACGGCTGTTCGCGCTCGACGCCGACAGCGGCAAGCCGTGCGACGGCTTTGGC
GATCACGGCCAGATCGATCTGAAGGCCGGCAACGAGATCACCACGGTCGGCTTCTACGAGGGGACCTCGCCGCCCGTTGT
CACCGACAAGGTGCTGATCATGGCCGGCGCCGTGATCGACAACTACTCCAACAAGGTGCCGTCGGGCGCGATCCGCGGCT
TCGACGTCTACTCGGGCAAGCTGTTATGGGCGTTCGATCCCGGCAATCCCGATCCGAACGAGATGCCGTCGGCGACGCAT
CATTTCACGCCGGGCTCGCCGAACGGCTGGAGCGTCGGCGCGGCCGACGAGGCGCTCGGCCTGGTCTACATCCCGCTTGG
CTCGAGCTCGCCGGACATCTGGGCCGGCAACCGCTCGGCCGACAACGAGCGCTATGATTCCGCGCTGGTCGCGCTCGACA
TCGCCACCGGCAAATTGCGCTGGTCGTTCCAGAACGTGCATCACGATCTCTGGGACATGGACATGCCGTCGCAGCCGAGT
CTGGTCGACATGCCAGGCCAAGACGGCGTGGTGCCGGCGATCTATGTGCCGGCCAAGACCGGCAACATCTTCGTGCTCGA
CCGCCGCGACGGGCACCTGCTGGTCCCCGCGCCCGAAAAGCCTGTGCCGCAAGGTGCGGCGCCCGGCGATCATCTGTCAC
CGACTCAGCCATTCTCCGAGCTGAGCTTCCGTCCGCGCAACCAGCTGACAGGCGCGCAGATGTGGGGCGCGACGATGTTC
GATCAGCTCGCCTGCCGTATCAAGTTCAAGCGGCTGCGCTACGAGGGCCCGTTCACGCCGCCCTCCGAGCAGGGCACGCT
GGTCTATCCCGGCGATTTCGGCATGTTCGAATGGGGCGGCATCGCGATCGATCCCGTCAGGAAGATCGCGATCGCCAATC
CGCAATCGATCCCGTTCGTGTCGCGGCTGGTGCCGCGCGGCAAGGACAATCCGGCGGCGCCGAACTCCGCGCATCCGCCG
GGCACCGAGCTCGGCGTGCAGCCGATGTACGGCACGCCCTATGGCGTCGATCTCGGCATCTTCCTGTCACCGCTCGGAAT
CCCCTGCATGGCCCCGCCCTGGGGCAGCCTCGCCGCCATCGATCTCAAGACCAACCAGATCGTCTGGCAGCACCGCGTCG
GCACCATTCGCGACCAGGCCCCCGTGCCACTGCCGTTCAAGCTGGGCGTGCCGATGCTCGGCGGCCCGATGGTGACCGCG
GGCGGCGTCGCCTTCCTCACCGGCACGATGGACGACTACATCCGCGCCTTCGACGTCAAGGATGGCCGGCTGCTCTGGCA
GGACCGCCTGCCGGCCGGCGGCCAGTCGACGCCGATGACGTACGAAGCCGGCGGCAGGCAGTATGTCGTCACCGTCGATG
GCGGCCACGGTTCGTTCGGCACCAAGCTCGGTGACTATGTCCGCGCCTACGCATTGCCCGGCAACGTCGCGAGCAGATAG

Upstream 100 bases:

>100_bases
CTCCTCACCATGAGGCAAGGAACTTCCGCCGCGGCCCGCCGTTCATGACGCGACTGCGGCGTCGCGCCGCGTTTCGTTCT
CATCAGCCTGGAGCCGCGCA

Downstream 100 bases:

>100_bases
CCGGCAGGTTCCAGCTCCGCACAGAGTGTCGCGGCGCGTTGGTGCTTTCGTCACGATGACTCTGGTTCCACATGAATTAC
GCCACCAGGAGGCCCGCGCC

Product: quinoprotein glucose dehydrogenase

Products: NA

Alternate protein names: Glucose dehydrogenase [pyrroloquinoline-quinone] [H]

Number of amino acids: Translated: 799; Mature: 798

Protein sequence:

>799_residues
MAAARHLQRAPLLTFTAVIVGLMGVALLAGGFWLAAIGGSLYYVIAGAALLGTAWLLWQRRASALWLYAALLLGTMIWAV
WEVGLDFWSLAPRGDVLAPLGVWLLLPFITAHLAGDMRSARWGLLAVLAVAVVVLGASLRGDRFGVNGALPQAAAATAGT
DPGPAEAQADWTAYGASNFGTRFSSLKQITANNVKNLQLAWEFQTGDRKGPDDPDEFTNEVTPLKIGDLLYTCSPHQIVF
ALDAATGKQRWTFDPKIEHHKNFQHMTCRGVAYHETKPGAVDVSGAAAPGECARRIFLPTDDGRLFALDADSGKPCDGFG
DHGQIDLKAGNEITTVGFYEGTSPPVVTDKVLIMAGAVIDNYSNKVPSGAIRGFDVYSGKLLWAFDPGNPDPNEMPSATH
HFTPGSPNGWSVGAADEALGLVYIPLGSSSPDIWAGNRSADNERYDSALVALDIATGKLRWSFQNVHHDLWDMDMPSQPS
LVDMPGQDGVVPAIYVPAKTGNIFVLDRRDGHLLVPAPEKPVPQGAAPGDHLSPTQPFSELSFRPRNQLTGAQMWGATMF
DQLACRIKFKRLRYEGPFTPPSEQGTLVYPGDFGMFEWGGIAIDPVRKIAIANPQSIPFVSRLVPRGKDNPAAPNSAHPP
GTELGVQPMYGTPYGVDLGIFLSPLGIPCMAPPWGSLAAIDLKTNQIVWQHRVGTIRDQAPVPLPFKLGVPMLGGPMVTA
GGVAFLTGTMDDYIRAFDVKDGRLLWQDRLPAGGQSTPMTYEAGGRQYVVTVDGGHGSFGTKLGDYVRAYALPGNVASR

Sequences:

>Translated_799_residues
MAAARHLQRAPLLTFTAVIVGLMGVALLAGGFWLAAIGGSLYYVIAGAALLGTAWLLWQRRASALWLYAALLLGTMIWAV
WEVGLDFWSLAPRGDVLAPLGVWLLLPFITAHLAGDMRSARWGLLAVLAVAVVVLGASLRGDRFGVNGALPQAAAATAGT
DPGPAEAQADWTAYGASNFGTRFSSLKQITANNVKNLQLAWEFQTGDRKGPDDPDEFTNEVTPLKIGDLLYTCSPHQIVF
ALDAATGKQRWTFDPKIEHHKNFQHMTCRGVAYHETKPGAVDVSGAAAPGECARRIFLPTDDGRLFALDADSGKPCDGFG
DHGQIDLKAGNEITTVGFYEGTSPPVVTDKVLIMAGAVIDNYSNKVPSGAIRGFDVYSGKLLWAFDPGNPDPNEMPSATH
HFTPGSPNGWSVGAADEALGLVYIPLGSSSPDIWAGNRSADNERYDSALVALDIATGKLRWSFQNVHHDLWDMDMPSQPS
LVDMPGQDGVVPAIYVPAKTGNIFVLDRRDGHLLVPAPEKPVPQGAAPGDHLSPTQPFSELSFRPRNQLTGAQMWGATMF
DQLACRIKFKRLRYEGPFTPPSEQGTLVYPGDFGMFEWGGIAIDPVRKIAIANPQSIPFVSRLVPRGKDNPAAPNSAHPP
GTELGVQPMYGTPYGVDLGIFLSPLGIPCMAPPWGSLAAIDLKTNQIVWQHRVGTIRDQAPVPLPFKLGVPMLGGPMVTA
GGVAFLTGTMDDYIRAFDVKDGRLLWQDRLPAGGQSTPMTYEAGGRQYVVTVDGGHGSFGTKLGDYVRAYALPGNVASR
>Mature_798_residues
AAARHLQRAPLLTFTAVIVGLMGVALLAGGFWLAAIGGSLYYVIAGAALLGTAWLLWQRRASALWLYAALLLGTMIWAVW
EVGLDFWSLAPRGDVLAPLGVWLLLPFITAHLAGDMRSARWGLLAVLAVAVVVLGASLRGDRFGVNGALPQAAAATAGTD
PGPAEAQADWTAYGASNFGTRFSSLKQITANNVKNLQLAWEFQTGDRKGPDDPDEFTNEVTPLKIGDLLYTCSPHQIVFA
LDAATGKQRWTFDPKIEHHKNFQHMTCRGVAYHETKPGAVDVSGAAAPGECARRIFLPTDDGRLFALDADSGKPCDGFGD
HGQIDLKAGNEITTVGFYEGTSPPVVTDKVLIMAGAVIDNYSNKVPSGAIRGFDVYSGKLLWAFDPGNPDPNEMPSATHH
FTPGSPNGWSVGAADEALGLVYIPLGSSSPDIWAGNRSADNERYDSALVALDIATGKLRWSFQNVHHDLWDMDMPSQPSL
VDMPGQDGVVPAIYVPAKTGNIFVLDRRDGHLLVPAPEKPVPQGAAPGDHLSPTQPFSELSFRPRNQLTGAQMWGATMFD
QLACRIKFKRLRYEGPFTPPSEQGTLVYPGDFGMFEWGGIAIDPVRKIAIANPQSIPFVSRLVPRGKDNPAAPNSAHPPG
TELGVQPMYGTPYGVDLGIFLSPLGIPCMAPPWGSLAAIDLKTNQIVWQHRVGTIRDQAPVPLPFKLGVPMLGGPMVTAG
GVAFLTGTMDDYIRAFDVKDGRLLWQDRLPAGGQSTPMTYEAGGRQYVVTVDGGHGSFGTKLGDYVRAYALPGNVASR

Specific function: GDH is probably involved in energy conservation rather than in sugar metabolism [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=801, Percent_Identity=56.6791510611735, Blast_Score=904, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017511
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.5.2 [H]

Molecular weight: Translated: 85562; Mature: 85431

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAARHLQRAPLLTFTAVIVGLMGVALLAGGFWLAAIGGSLYYVIAGAALLGTAWLLWQR
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHEEHHCCCCEEEHHHHHHHHHHHHHHHH
RASALWLYAALLLGTMIWAVWEVGLDFWSLAPRGDVLAPLGVWLLLPFITAHLAGDMRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHH
RWGLLAVLAVAVVVLGASLRGDRFGVNGALPQAAAATAGTDPGPAEAQADWTAYGASNFG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEECCCHHH
TRFSSLKQITANNVKNLQLAWEFQTGDRKGPDDPDEFTNEVTPLKIGDLLYTCSPHQIVF
HHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHCCCCCEEECCEEEECCCCEEEE
ALDAATGKQRWTFDPKIEHHKNFQHMTCRGVAYHETKPGAVDVSGAAAPGECARRIFLPT
EEECCCCCCCEEECCCHHHCCCCCEEEECCEEEECCCCCEEECCCCCCCCHHHCEEEEEC
DDGRLFALDADSGKPCDGFGDHGQIDLKAGNEITTVGFYEGTSPPVVTDKVLIMAGAVID
CCCEEEEEECCCCCCCCCCCCCCEEEEECCCEEEEEEEECCCCCCCCCCCEEEEECHHHH
NYSNKVPSGAIRGFDVYSGKLLWAFDPGNPDPNEMPSATHHFTPGSPNGWSVGAADEALG
CCCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
LVYIPLGSSSPDIWAGNRSADNERYDSALVALDIATGKLRWSFQNVHHDLWDMDMPSQPS
EEEEECCCCCCCEEECCCCCCCHHHCCEEEEEEEECCEEEEEHHHHHHHHHCCCCCCCCC
LVDMPGQDGVVPAIYVPAKTGNIFVLDRRDGHLLVPAPEKPVPQGAAPGDHLSPTQPFSE
EEECCCCCCCEEEEEEECCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHH
LSFRPRNQLTGAQMWGATMFDQLACRIKFKRLRYEGPFTPPSEQGTLVYPGDFGMFEWGG
CCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCEEECCCCCCEECCC
IAIDPVRKIAIANPQSIPFVSRLVPRGKDNPAAPNSAHPPGTELGVQPMYGTPYGVDLGI
EEECCHHEEEECCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
FLSPLGIPCMAPPWGSLAAIDLKTNQIVWQHRVGTIRDQAPVPLPFKLGVPMLGGPMVTA
HCCCCCCCCCCCCCCCEEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEC
GGVAFLTGTMDDYIRAFDVKDGRLLWQDRLPAGGQSTPMTYEAGGRQYVVTVDGGHGSFG
CCEEEEECCHHHHHEEECCCCCEEEEECCCCCCCCCCCEEEECCCCEEEEEEECCCCCCH
TKLGDYVRAYALPGNVASR
HHHHHHHEEEECCCHHCCC
>Mature Secondary Structure 
AAARHLQRAPLLTFTAVIVGLMGVALLAGGFWLAAIGGSLYYVIAGAALLGTAWLLWQR
CHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHEEHHCCCCEEEHHHHHHHHHHHHHHHH
RASALWLYAALLLGTMIWAVWEVGLDFWSLAPRGDVLAPLGVWLLLPFITAHLAGDMRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHH
RWGLLAVLAVAVVVLGASLRGDRFGVNGALPQAAAATAGTDPGPAEAQADWTAYGASNFG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEECCCHHH
TRFSSLKQITANNVKNLQLAWEFQTGDRKGPDDPDEFTNEVTPLKIGDLLYTCSPHQIVF
HHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHCCCCCEEECCEEEECCCCEEEE
ALDAATGKQRWTFDPKIEHHKNFQHMTCRGVAYHETKPGAVDVSGAAAPGECARRIFLPT
EEECCCCCCCEEECCCHHHCCCCCEEEECCEEEECCCCCEEECCCCCCCCHHHCEEEEEC
DDGRLFALDADSGKPCDGFGDHGQIDLKAGNEITTVGFYEGTSPPVVTDKVLIMAGAVID
CCCEEEEEECCCCCCCCCCCCCCEEEEECCCEEEEEEEECCCCCCCCCCCEEEEECHHHH
NYSNKVPSGAIRGFDVYSGKLLWAFDPGNPDPNEMPSATHHFTPGSPNGWSVGAADEALG
CCCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
LVYIPLGSSSPDIWAGNRSADNERYDSALVALDIATGKLRWSFQNVHHDLWDMDMPSQPS
EEEEECCCCCCCEEECCCCCCCHHHCCEEEEEEEECCEEEEEHHHHHHHHHCCCCCCCCC
LVDMPGQDGVVPAIYVPAKTGNIFVLDRRDGHLLVPAPEKPVPQGAAPGDHLSPTQPFSE
EEECCCCCCCEEEEEEECCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHH
LSFRPRNQLTGAQMWGATMFDQLACRIKFKRLRYEGPFTPPSEQGTLVYPGDFGMFEWGG
CCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCEEECCCCCCEECCC
IAIDPVRKIAIANPQSIPFVSRLVPRGKDNPAAPNSAHPPGTELGVQPMYGTPYGVDLGI
EEECCHHEEEECCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
FLSPLGIPCMAPPWGSLAAIDLKTNQIVWQHRVGTIRDQAPVPLPFKLGVPMLGGPMVTA
HCCCCCCCCCCCCCCCEEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEC
GGVAFLTGTMDDYIRAFDVKDGRLLWQDRLPAGGQSTPMTYEAGGRQYVVTVDGGHGSFG
CCEEEEECCHHHHHEEECCCCCEEEEECCCCCCCCCCCEEEECCCCEEEEEEECCCCCCH
TKLGDYVRAYALPGNVASR
HHHHHHHEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2228962; 8419307; 8202364; 9278503; 8509415; 8554505 [H]