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The map label for this gene is aglA [H]

Identifier: 146337645

GI number: 146337645

Start: 516493

End: 518091

Strand: Direct

Name: aglA [H]

Synonym: BRADO0511

Alternate gene names: 146337645

Gene position: 516493-518091 (Clockwise)

Preceding gene: 146337643

Following gene: 146337647

Centisome position: 6.93

GC content: 66.92

Gene sequence:

>1599_bases
ATGGCGGAGCAGGGCGCCTGGTGGCGCGAGGGGATTTTCTACCAGATCTATCCGCGCTCGTTCCAGGACAGCGATGGCGA
CGGGGTCGGCGATCTCACCGGCATCATCCATCGCCTGCCTTATCTGATGACGCTCGGGGTCGACGCGATCTGGCTGTCGC
CGATCTTCACCTCGCCGATGGCCGATTTCGGCTACGACATCGCCGACTATACCGGCATCGATCCCGTGTTCGGCACGATG
GAGGATTTCGACGCGCTGGTGAAGGCCGCGCATGACGGCGGGCTGAAGCTGATCCTCGATCTCGTGCCGAACCACACCTC
CGATCAGCATCCGTGGTTTCTGCAGGCGCGGCAGTCGCGCGACGATCCGCACCGCGACTGGTACATCTGGCGCGATCCGG
CGGCCGATGGTGGACCGCCGAACAACTGGCTGTCGGAATTCGGCGGCAGCGCGTGGCAGTTCGATTCGAGGACGGGCCAG
TACTATTATCACGCCTTCCTGGCGCAGCAGCCGGATCTGAACTGGCGCAATCCGGCGGTGCGCGCGGCGATCTACAACGT
GATGCGGTTCTGGCTGCGCAAGGGTGTCGACGGTTTTCGCGTCGATGTGATCTGGCACCTGATCAAGGACGCCGCGTTTC
GCGACAATCCGGCCAATCCCGATTATCACGGTGGACGGCCGCCGCACGAGCAGATCATCTCGCGCTACTCCGCCGACCAG
CCGGAGGTGCACGAGGTCGTGGCCGAGATGCGCGCGGTCATCGACGAGTTCGAGGACCGCGTGCTGATCGGCGAGATCTA
CCTGCCGCTCGAGCGGCTGATGACCTATTACGGCAAGGACCTCGGCGGCGCGCACCTGCCGTTCAATTTCGCGCTGCTGT
CGGCGCCCTGGCACGCGCGCGAGATCGAGACCATCATCGCCGATTACGAGGCTGCGCTGCCGGCCGGCGCCTGGCCGAAC
TGGGTGCTCGGCAATCATGACCGGCCGCGCGTGGCGAGCCGTGTCGGCGAAGACCAGGCGCGGGTGGCGGCGATGCTGCT
GCTCACCCTGCGCGGCACGCCGACGCTGTATTACGGCGACGAGATCGGCATGCATCAGGTGACGATCAGCCCGGAGCAGG
TGCGCGATCCCTTCGAGAGGAACGTGCCCGGCATCGGCGTCGGCCGCGACGGCTGCCGCACCCCGATGCAATGGAGCGCG
CTGCCGGGGGCAGGCTTCAGCCACGCCACGCCGTGGCTGCCGGTCGCCGAGGATTACACCCGCGAGAACGTTGTCAATCT
CAGCGCCGACCGCCGCTCGATCCTCAACCTCTACCGCGCGCTCATCCGCTTGCGGAAGCAGCACCGCGTGCTCGTCACCG
GCAACTACCGTCCCGTCGCGGCGCAGGGCGATCTGCTGCTGTACCGCCGCGAGGGTGACGGCGAGGTGCTCACGGTTGCG
CTCAATCTCGCCGACGAGCCGGTGTCGATCGCGACCGAAGGCAACGGCCTCGACGGCGACCTCCTGCTGTCCACCTGGCT
CGACCGCGACGGCGAGCGGATCGACGGCACGCTGGACCTGCGCGGCAATGAGGGTGTCGTGATCGGGCGGAGGGCGTAG

Upstream 100 bases:

>100_bases
CCGTTCGTAGCGGCCTCATGCCAAGAGCACGGCCGGGCTTGTGAACCTGCCGGCTGTTCCGGCGTTAGGCCGCACGGTTG
CGAGCAGAAAGCGGTTTGAG

Downstream 100 bases:

>100_bases
TTGCCGGTCATTGTTGCGCGGCGGCGGCACTCCACATTCAGTGTCGTCCCGGGCTTGACCCGGGACCCATAACCACAGGG
AGCCGCTTGAGGCAGGCTGG

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 531

Protein sequence:

>532_residues
MAEQGAWWREGIFYQIYPRSFQDSDGDGVGDLTGIIHRLPYLMTLGVDAIWLSPIFTSPMADFGYDIADYTGIDPVFGTM
EDFDALVKAAHDGGLKLILDLVPNHTSDQHPWFLQARQSRDDPHRDWYIWRDPAADGGPPNNWLSEFGGSAWQFDSRTGQ
YYYHAFLAQQPDLNWRNPAVRAAIYNVMRFWLRKGVDGFRVDVIWHLIKDAAFRDNPANPDYHGGRPPHEQIISRYSADQ
PEVHEVVAEMRAVIDEFEDRVLIGEIYLPLERLMTYYGKDLGGAHLPFNFALLSAPWHAREIETIIADYEAALPAGAWPN
WVLGNHDRPRVASRVGEDQARVAAMLLLTLRGTPTLYYGDEIGMHQVTISPEQVRDPFERNVPGIGVGRDGCRTPMQWSA
LPGAGFSHATPWLPVAEDYTRENVVNLSADRRSILNLYRALIRLRKQHRVLVTGNYRPVAAQGDLLLYRREGDGEVLTVA
LNLADEPVSIATEGNGLDGDLLLSTWLDRDGERIDGTLDLRGNEGVVIGRRA

Sequences:

>Translated_532_residues
MAEQGAWWREGIFYQIYPRSFQDSDGDGVGDLTGIIHRLPYLMTLGVDAIWLSPIFTSPMADFGYDIADYTGIDPVFGTM
EDFDALVKAAHDGGLKLILDLVPNHTSDQHPWFLQARQSRDDPHRDWYIWRDPAADGGPPNNWLSEFGGSAWQFDSRTGQ
YYYHAFLAQQPDLNWRNPAVRAAIYNVMRFWLRKGVDGFRVDVIWHLIKDAAFRDNPANPDYHGGRPPHEQIISRYSADQ
PEVHEVVAEMRAVIDEFEDRVLIGEIYLPLERLMTYYGKDLGGAHLPFNFALLSAPWHAREIETIIADYEAALPAGAWPN
WVLGNHDRPRVASRVGEDQARVAAMLLLTLRGTPTLYYGDEIGMHQVTISPEQVRDPFERNVPGIGVGRDGCRTPMQWSA
LPGAGFSHATPWLPVAEDYTRENVVNLSADRRSILNLYRALIRLRKQHRVLVTGNYRPVAAQGDLLLYRREGDGEVLTVA
LNLADEPVSIATEGNGLDGDLLLSTWLDRDGERIDGTLDLRGNEGVVIGRRA
>Mature_531_residues
AEQGAWWREGIFYQIYPRSFQDSDGDGVGDLTGIIHRLPYLMTLGVDAIWLSPIFTSPMADFGYDIADYTGIDPVFGTME
DFDALVKAAHDGGLKLILDLVPNHTSDQHPWFLQARQSRDDPHRDWYIWRDPAADGGPPNNWLSEFGGSAWQFDSRTGQY
YYHAFLAQQPDLNWRNPAVRAAIYNVMRFWLRKGVDGFRVDVIWHLIKDAAFRDNPANPDYHGGRPPHEQIISRYSADQP
EVHEVVAEMRAVIDEFEDRVLIGEIYLPLERLMTYYGKDLGGAHLPFNFALLSAPWHAREIETIIADYEAALPAGAWPNW
VLGNHDRPRVASRVGEDQARVAAMLLLTLRGTPTLYYGDEIGMHQVTISPEQVRDPFERNVPGIGVGRDGCRTPMQWSAL
PGAGFSHATPWLPVAEDYTRENVVNLSADRRSILNLYRALIRLRKQHRVLVTGNYRPVAAQGDLLLYRREGDGEVLTVAL
NLADEPVSIATEGNGLDGDLLLSTWLDRDGERIDGTLDLRGNEGVVIGRRA

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=545, Percent_Identity=36.5137614678899, Blast_Score=346, Evalue=4e-95,
Organism=Homo sapiens, GI65506891, Length=107, Percent_Identity=38.3177570093458, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI61744479, Length=107, Percent_Identity=38.3177570093458, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI61744481, Length=107, Percent_Identity=38.3177570093458, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI61744475, Length=107, Percent_Identity=38.3177570093458, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI61744477, Length=107, Percent_Identity=38.3177570093458, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI61744483, Length=107, Percent_Identity=38.3177570093458, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1790687, Length=520, Percent_Identity=39.0384615384615, Blast_Score=350, Evalue=2e-97,
Organism=Escherichia coli, GI1786604, Length=481, Percent_Identity=24.948024948025, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI87081873, Length=292, Percent_Identity=23.972602739726, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI32565753, Length=508, Percent_Identity=26.5748031496063, Blast_Score=156, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI25147709, Length=549, Percent_Identity=25.8652094717668, Blast_Score=137, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6322245, Length=573, Percent_Identity=33.1588132635253, Blast_Score=297, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6321726, Length=546, Percent_Identity=34.981684981685, Blast_Score=292, Evalue=9e-80,
Organism=Saccharomyces cerevisiae, GI6322241, Length=550, Percent_Identity=35.2727272727273, Blast_Score=290, Evalue=5e-79,
Organism=Saccharomyces cerevisiae, GI6322021, Length=550, Percent_Identity=35.2727272727273, Blast_Score=290, Evalue=5e-79,
Organism=Saccharomyces cerevisiae, GI6324416, Length=549, Percent_Identity=35.1548269581056, Blast_Score=288, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6319776, Length=559, Percent_Identity=32.2003577817531, Blast_Score=275, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6321731, Length=559, Percent_Identity=32.0214669051878, Blast_Score=274, Evalue=3e-74,
Organism=Drosophila melanogaster, GI24586593, Length=503, Percent_Identity=45.3280318091451, Blast_Score=397, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24586589, Length=512, Percent_Identity=44.3359375, Blast_Score=389, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24583745, Length=550, Percent_Identity=41.2727272727273, Blast_Score=380, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24586591, Length=555, Percent_Identity=39.6396396396396, Blast_Score=378, Evalue=1e-105,
Organism=Drosophila melanogaster, GI45549022, Length=543, Percent_Identity=39.7790055248619, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24586599, Length=489, Percent_Identity=41.9222903885481, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24586597, Length=510, Percent_Identity=41.9607843137255, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24583747, Length=527, Percent_Identity=39.8481973434535, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24583749, Length=527, Percent_Identity=39.8481973434535, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI221330053, Length=513, Percent_Identity=40.1559454191033, Blast_Score=353, Evalue=1e-97,
Organism=Drosophila melanogaster, GI24586587, Length=470, Percent_Identity=41.4893617021277, Blast_Score=340, Evalue=1e-93,
Organism=Drosophila melanogaster, GI281360393, Length=450, Percent_Identity=42.2222222222222, Blast_Score=315, Evalue=7e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 59954; Mature: 59823

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQGAWWREGIFYQIYPRSFQDSDGDGVGDLTGIIHRLPYLMTLGVDAIWLSPIFTSPM
CCCCCCCHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCHHHCCCH
ADFGYDIADYTGIDPVFGTMEDFDALVKAAHDGGLKLILDLVPNHTSDQHPWFLQARQSR
HHHCCCHHHCCCCCHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEECCCC
DDPHRDWYIWRDPAADGGPPNNWLSEFGGSAWQFDSRTGQYYYHAFLAQQPDLNWRNPAV
CCCCCCEEEEECCCCCCCCCHHHHHHHCCCEEEECCCCCCEEEEEEECCCCCCCCCCHHH
RAAIYNVMRFWLRKGVDGFRVDVIWHLIKDAAFRDNPANPDYHGGRPPHEQIISRYSADQ
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCC
PEVHEVVAEMRAVIDEFEDRVLIGEIYLPLERLMTYYGKDLGGAHLPFNFALLSAPWHAR
CHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHH
EIETIIADYEAALPAGAWPNWVLGNHDRPRVASRVGEDQARVAAMLLLTLRGTPTLYYGD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCEEEECC
EIGMHQVTISPEQVRDPFERNVPGIGVGRDGCRTPMQWSALPGAGFSHATPWLPVAEDYT
CCCCEEEEECHHHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHC
RENVVNLSADRRSILNLYRALIRLRKQHRVLVTGNYRPVAAQGDLLLYRREGDGEVLTVA
CCCEEECCHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEECCCEEEEEECCCCCEEEEE
LNLADEPVSIATEGNGLDGDLLLSTWLDRDGERIDGTLDLRGNEGVVIGRRA
EECCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCEEEECCC
>Mature Secondary Structure 
AEQGAWWREGIFYQIYPRSFQDSDGDGVGDLTGIIHRLPYLMTLGVDAIWLSPIFTSPM
CCCCCCHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCHHHCCCH
ADFGYDIADYTGIDPVFGTMEDFDALVKAAHDGGLKLILDLVPNHTSDQHPWFLQARQSR
HHHCCCHHHCCCCCHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEECCCC
DDPHRDWYIWRDPAADGGPPNNWLSEFGGSAWQFDSRTGQYYYHAFLAQQPDLNWRNPAV
CCCCCCEEEEECCCCCCCCCHHHHHHHCCCEEEECCCCCCEEEEEEECCCCCCCCCCHHH
RAAIYNVMRFWLRKGVDGFRVDVIWHLIKDAAFRDNPANPDYHGGRPPHEQIISRYSADQ
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCC
PEVHEVVAEMRAVIDEFEDRVLIGEIYLPLERLMTYYGKDLGGAHLPFNFALLSAPWHAR
CHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHH
EIETIIADYEAALPAGAWPNWVLGNHDRPRVASRVGEDQARVAAMLLLTLRGTPTLYYGD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCEEEECC
EIGMHQVTISPEQVRDPFERNVPGIGVGRDGCRTPMQWSALPGAGFSHATPWLPVAEDYT
CCCCEEEEECHHHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHC
RENVVNLSADRRSILNLYRALIRLRKQHRVLVTGNYRPVAAQGDLLLYRREGDGEVLTVA
CCCEEECCHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEECCCEEEEEECCCCCEEEEE
LNLADEPVSIATEGNGLDGDLLLSTWLDRDGERIDGTLDLRGNEGVVIGRRA
EECCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]