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The map label for this gene is gmr [H]

Identifier: 146337636

GI number: 146337636

Start: 504542

End: 506320

Strand: Reverse

Name: gmr [H]

Synonym: BRADO0501

Alternate gene names: 146337636

Gene position: 506320-504542 (Counterclockwise)

Preceding gene: 146337637

Following gene: 146337635

Centisome position: 6.79

GC content: 65.6

Gene sequence:

>1779_bases
ATGTACAGCAGTGACCGATTCAACTTTTCTCCCGACACGAACGACGGGCTGGGCTCGCCCGAGGCCGAACTGCGCTTCCT
GCGCGGCGTCCTCAGCCAGCTGCCGGCCGGCGTCACCGTCCAGGACGAGCAAGGCCGGTTTCTGCTCGTCAACGAAGCCG
CGGCCGCTCAGCTGGGCACCGCCGCCGACAGCGCCGACCGCATGCCGGCGCCGCATCTCGACGGCCGGCGCCTGGCCTGC
CTCGAGACCATCGGCCGGGGGCGCACCGTGATCGCCGAGGAAAAGGTCGTCGGAGGACAGGGCACGCAGACGCTGCTGAC
CGCGCACCGGCCGGTCCACATCGGCGACCGGCAGTTGGTCATCTCGAGCTCGGCGGACATCACCGAGCAGAAGGAGTTCG
AGGATCAGCTGTTCCGCGCCGCCTATTACGACGAGCTCACCGGCCTGCCCTTGCGCCGCGTGGCTCAGCATCGCGCGGAT
AATCTGGTGCGCCGCGGCCGCGTCGAGGGCCGCTTCGCGCTGGCCTTCCTCGATCTCGACAATTTCAAATACATCAACGA
CTACTACGGCCACGCCACCGGCGATGCGCTGCTGGTGGAGTTCGCCAAGCGGATCAGCCGCGACCTGCGTGACACGGACC
TGCTGTCGCGCATCAGCGGCGACGAATTCCTGCTGCTGCTGCACCCGATCGAGCGGGCCGAGGAGATCGCCGAGTTTCTG
CACGCCTTGCTCGATCGCCTCAGCGCGCCGTTCTTCATCGGCGGCGCCGAGGTGTTCGCCTCCGCGTCGGTCGGCGTCAG
CCTGTATCCCGAGCACGGCGCGAGCTACGACGTGCTGCGCCAGAATGCCGACCTCGCGATGTATCGCGTCAAGAACAGCG
GCAAGGGCACGCTCGCCTTCTTCTCCAGCGCAATGGAGCACGAAGCGCTGGCGCGCATGAAGGTCGAGCAGTCGCTGCGG
CTCGCCATTCTCGAGAAGCGCTTCTGCTGCGCGTTCCAGGCCAAGGTCGACATCCGTACCGAGGAGATCAAGGGCATCGA
GGCGCTGGTGCGGCTGCGCGACAACGAGGACGTGATCCAGGCGCCCGGAGCATTCATCAATCTCGCGGTCGAGCTCGGCC
TGATCGACGAGCTGACGCATCTCGTGCTCGACGAGATCGTCAAGTCAATCGATCTGATCAACGCCACGTTCGGGCCCGAC
GCGACGATCAGCATCAATGTCGCCGCCAAGCAGGCGTCGAACCCTGAATTCATGCAGCCGTTCGCCAGGGCGCTCGAGGC
GACCGGATTCCCGAAGCGCTTCATGGTCGAGGTCACCGAGGATGCCTTCGTGACCCGCAGCCATTTCCAGGACGAGATCG
TGCCGCTGCTGCGCGGAATCGGCGTCGGCATCTCGATCGACGATTTCGGCATCGGCTATTCGTCGCTGTCGGCGCTCGCC
GACATCACCGCCGACGAGATCAAGATCGACCGCTCCTTCATCACGGACATCCACAAGCGGCCGCGCAGCCAGGGCATCCT
CCGCGCGATCGAATCGCTGAGCGAGGCGCTCGGCATGACCGTCATCGCCGAGGGCATCGAGTCCTTCGAGGAGCTTGCCT
ATCTGCAGGCCGCGACCAAGATCCGCTACGCCCAGGGCTACTACTTCTCGCGCCCGATCTTTCTGGAGGAGCTGAAGCCC
GCGGCTCCCTATGCAAGCGAAGCGCGTATCAGCATGGCCAGTCGCGCTGTGCAGGAAAACCGCCAGTCTTACGCACGCAG
CAGCCGCTATCGGCGCTGA

Upstream 100 bases:

>100_bases
GCGGCACAAAGCTCTGCTTTTCCCGCGACTTGGCTTCGGCGTTCCGTGTTTCTACGTAGCGCTTAACTAAAATGAAGCGG
GAACTTCTCACAATCGGCGC

Downstream 100 bases:

>100_bases
ATTCGGACGGAGCAACGGAGGCCGATTCATCAGCACAAAGTATGAGCCATCCCGAAGCGCCTGCGAAAGCGCCTTGACCC
GGCCCGAACCTGCACACTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MYSSDRFNFSPDTNDGLGSPEAELRFLRGVLSQLPAGVTVQDEQGRFLLVNEAAAAQLGTAADSADRMPAPHLDGRRLAC
LETIGRGRTVIAEEKVVGGQGTQTLLTAHRPVHIGDRQLVISSSADITEQKEFEDQLFRAAYYDELTGLPLRRVAQHRAD
NLVRRGRVEGRFALAFLDLDNFKYINDYYGHATGDALLVEFAKRISRDLRDTDLLSRISGDEFLLLLHPIERAEEIAEFL
HALLDRLSAPFFIGGAEVFASASVGVSLYPEHGASYDVLRQNADLAMYRVKNSGKGTLAFFSSAMEHEALARMKVEQSLR
LAILEKRFCCAFQAKVDIRTEEIKGIEALVRLRDNEDVIQAPGAFINLAVELGLIDELTHLVLDEIVKSIDLINATFGPD
ATISINVAAKQASNPEFMQPFARALEATGFPKRFMVEVTEDAFVTRSHFQDEIVPLLRGIGVGISIDDFGIGYSSLSALA
DITADEIKIDRSFITDIHKRPRSQGILRAIESLSEALGMTVIAEGIESFEELAYLQAATKIRYAQGYYFSRPIFLEELKP
AAPYASEARISMASRAVQENRQSYARSSRYRR

Sequences:

>Translated_592_residues
MYSSDRFNFSPDTNDGLGSPEAELRFLRGVLSQLPAGVTVQDEQGRFLLVNEAAAAQLGTAADSADRMPAPHLDGRRLAC
LETIGRGRTVIAEEKVVGGQGTQTLLTAHRPVHIGDRQLVISSSADITEQKEFEDQLFRAAYYDELTGLPLRRVAQHRAD
NLVRRGRVEGRFALAFLDLDNFKYINDYYGHATGDALLVEFAKRISRDLRDTDLLSRISGDEFLLLLHPIERAEEIAEFL
HALLDRLSAPFFIGGAEVFASASVGVSLYPEHGASYDVLRQNADLAMYRVKNSGKGTLAFFSSAMEHEALARMKVEQSLR
LAILEKRFCCAFQAKVDIRTEEIKGIEALVRLRDNEDVIQAPGAFINLAVELGLIDELTHLVLDEIVKSIDLINATFGPD
ATISINVAAKQASNPEFMQPFARALEATGFPKRFMVEVTEDAFVTRSHFQDEIVPLLRGIGVGISIDDFGIGYSSLSALA
DITADEIKIDRSFITDIHKRPRSQGILRAIESLSEALGMTVIAEGIESFEELAYLQAATKIRYAQGYYFSRPIFLEELKP
AAPYASEARISMASRAVQENRQSYARSSRYRR
>Mature_592_residues
MYSSDRFNFSPDTNDGLGSPEAELRFLRGVLSQLPAGVTVQDEQGRFLLVNEAAAAQLGTAADSADRMPAPHLDGRRLAC
LETIGRGRTVIAEEKVVGGQGTQTLLTAHRPVHIGDRQLVISSSADITEQKEFEDQLFRAAYYDELTGLPLRRVAQHRAD
NLVRRGRVEGRFALAFLDLDNFKYINDYYGHATGDALLVEFAKRISRDLRDTDLLSRISGDEFLLLLHPIERAEEIAEFL
HALLDRLSAPFFIGGAEVFASASVGVSLYPEHGASYDVLRQNADLAMYRVKNSGKGTLAFFSSAMEHEALARMKVEQSLR
LAILEKRFCCAFQAKVDIRTEEIKGIEALVRLRDNEDVIQAPGAFINLAVELGLIDELTHLVLDEIVKSIDLINATFGPD
ATISINVAAKQASNPEFMQPFARALEATGFPKRFMVEVTEDAFVTRSHFQDEIVPLLRGIGVGISIDDFGIGYSSLSALA
DITADEIKIDRSFITDIHKRPRSQGILRAIESLSEALGMTVIAEGIESFEELAYLQAATKIRYAQGYYFSRPIFLEELKP
AAPYASEARISMASRAVQENRQSYARSSRYRR

Specific function: Part of a 2 protein system that seems to be dedicated to transcription of csgD. This protein decreases csgD transcription and thus decreases expression of adhesive curli fimbriae genes csgEFG, csgBAC/ymaD and adrA (yaic). Activity of this protein is antag

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=458, Percent_Identity=33.6244541484716, Blast_Score=249, Evalue=4e-67,
Organism=Escherichia coli, GI87081921, Length=433, Percent_Identity=29.5612009237875, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1790496, Length=240, Percent_Identity=32.5, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI87081845, Length=283, Percent_Identity=30.0353356890459, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI226510982, Length=486, Percent_Identity=23.8683127572016, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787055, Length=449, Percent_Identity=26.2806236080178, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1788502, Length=261, Percent_Identity=29.8850574712644, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI87081881, Length=189, Percent_Identity=35.978835978836, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1788956, Length=160, Percent_Identity=38.125, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788381, Length=406, Percent_Identity=26.6009852216749, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI87081743, Length=237, Percent_Identity=28.6919831223629, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI87081977, Length=179, Percent_Identity=29.608938547486, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87081980, Length=263, Percent_Identity=25.8555133079848, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788849, Length=207, Percent_Identity=28.5024154589372, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1786507, Length=238, Percent_Identity=26.890756302521, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1787410, Length=154, Percent_Identity=31.1688311688312, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786584, Length=171, Percent_Identity=30.9941520467836, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87082096, Length=225, Percent_Identity=27.5555555555556, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787816, Length=160, Percent_Identity=31.875, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787262, Length=132, Percent_Identity=30.3030303030303, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI145693134, Length=138, Percent_Identity=28.9855072463768, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=31.547619047619, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF00989 PAS [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 65664; Mature: 65664

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSSDRFNFSPDTNDGLGSPEAELRFLRGVLSQLPAGVTVQDEQGRFLLVNEAAAAQLGT
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECHHHHHHCC
AADSADRMPAPHLDGRRLACLETIGRGRTVIAEEKVVGGQGTQTLLTAHRPVHIGDRQLV
CCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCHHHEECCCCEEECCCEEE
ISSSADITEQKEFEDQLFRAAYYDELTGLPLRRVAQHRADNLVRRGRVEGRFALAFLDLD
EECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECC
NFKYINDYYGHATGDALLVEFAKRISRDLRDTDLLSRISGDEFLLLLHPIERAEEIAEFL
CCEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHH
HALLDRLSAPFFIGGAEVFASASVGVSLYPEHGASYDVLRQNADLAMYRVKNSGKGTLAF
HHHHHHCCCCEEEEHHHHHHHCCCCEEECCCCCCCHHHHHCCCCEEEEEECCCCCCHHHH
FSSAMEHEALARMKVEQSLRLAILEKRFCCAFQAKVDIRTEEIKGIEALVRLRDNEDVIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHCCCCCHHH
APGAFINLAVELGLIDELTHLVLDEIVKSIDLINATFGPDATISINVAAKQASNPEFMQP
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHHH
FARALEATGFPKRFMVEVTEDAFVTRSHFQDEIVPLLRGIGVGISIDDFGIGYSSLSALA
HHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHH
DITADEIKIDRSFITDIHKRPRSQGILRAIESLSEALGMTVIAEGIESFEELAYLQAATK
HCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRYAQGYYFSRPIFLEELKPAAPYASEARISMASRAVQENRQSYARSSRYRR
HHHHCCEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYSSDRFNFSPDTNDGLGSPEAELRFLRGVLSQLPAGVTVQDEQGRFLLVNEAAAAQLGT
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECHHHHHHCC
AADSADRMPAPHLDGRRLACLETIGRGRTVIAEEKVVGGQGTQTLLTAHRPVHIGDRQLV
CCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCHHHEECCCCEEECCCEEE
ISSSADITEQKEFEDQLFRAAYYDELTGLPLRRVAQHRADNLVRRGRVEGRFALAFLDLD
EECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECC
NFKYINDYYGHATGDALLVEFAKRISRDLRDTDLLSRISGDEFLLLLHPIERAEEIAEFL
CCEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHH
HALLDRLSAPFFIGGAEVFASASVGVSLYPEHGASYDVLRQNADLAMYRVKNSGKGTLAF
HHHHHHCCCCEEEEHHHHHHHCCCCEEECCCCCCCHHHHHCCCCEEEEEECCCCCCHHHH
FSSAMEHEALARMKVEQSLRLAILEKRFCCAFQAKVDIRTEEIKGIEALVRLRDNEDVIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHCCCCCHHH
APGAFINLAVELGLIDELTHLVLDEIVKSIDLINATFGPDATISINVAAKQASNPEFMQP
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHHH
FARALEATGFPKRFMVEVTEDAFVTRSHFQDEIVPLLRGIGVGISIDDFGIGYSSLSALA
HHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHH
DITADEIKIDRSFITDIHKRPRSQGILRAIESLSEALGMTVIAEGIESFEELAYLQAATK
HCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRYAQGYYFSRPIFLEELKPAAPYASEARISMASRAVQENRQSYARSSRYRR
HHHHCCEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]