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The map label for this gene is phr [H]

Identifier: 146337586

GI number: 146337586

Start: 453896

End: 455116

Strand: Direct

Name: phr [H]

Synonym: BRADO0442

Alternate gene names: 146337586

Gene position: 453896-455116 (Clockwise)

Preceding gene: 146337585

Following gene: 146337587

Centisome position: 6.09

GC content: 72.07

Gene sequence:

>1221_bases
ATGACGGGGAAGCTACCGATCGCCACCCGCGCGGCAGGGCTCGCGCGTTTGCAGACGGTGCTGCCGCGGCTCGGCCGCGC
CTATGCGGCGGGACGCAACCATGATCATGGGCCCGGCCGGCCGCAGGCGGTGTCGGGACTGTCGCCCTGGATCCGGCGGC
GGCTCGTCACCGAGGAGGAGGTGGTGCGCGCCGCCGTGGCGGCGCATGGCGGGGCGGCGGACAAGTTCGTCGAGGAAGTG
ATCTGGCGCGGCTATTTCAAGGGCTGGCTGGAGCGGCGGCCGCAGGTCTGGACGAGCTATCTACGCGGCCGCGACGCCGA
TCTCGAGCGCCTCGATAGCGACGGCGCGCTGCAGGCGCGCGTGGCGGCGGCGGAGGCCGGACGCACCGGCCTCGCATGCT
TCGACGCCTTCGCGCAGGAGCTCGTCGCCACCGGCATGCTGCACAACCATGCGCGGATGTGGTTCGCCTCGCTGTGGATC
TTCACGCTCGGCCTGCCCTGGCGGCTCGGCGCGGATTTCTTTCTGCGTCATCTGCTCGACGGTGATCCGGCGTCGAACAC
GCTGGGCTGGCGCTGGGTGGCCGGGCTGCACACAAGGGGCAAGGTCTATGCGGCGACGGCTTCGAACATCGCGCAGTACA
GCGCCGGCCGCTTCGCGCCGCGGCCGGAGGACATCGTGATCCCGGCGCAAGGACTGGAAGCCGAGGAGCCGGAGGGCCTG
CCGTCGCTGCGGCCGCTGCGCGTGCTTATCGCGCCCCGGCGCGACGTGCCGTCGCTGTGGCTCATCACGGAGGAGGATTG
CGGCCTTACCGATTTCGACTCCGACGGCTTCACCTGGCGCGGCGCGGCGACGCTGGCGGCCTCGCAGCTGCGCTCGCCGC
GTCCGGTCGCGGAGCAGGTTGCGGCGTTCGAGGCGGCTGCGCTGCGCGATGGCACGACCCGTATTGGACTGACCGCCGCC
GCGCTGAAGGCGGTGGATCCGGCGGCGCTGGTCGCCTGCGCGCAGGACGCCGGCGCGACGCAGATCGTCACCGCCGAGGT
GCCGCAGGGGCCGCTGCGTGATTGGCTCGATGCCGCGGCGCCTGCGCTTGCGGCTGCTGGGCTGACGCTCGCCGAATGGC
GCCGGCCGTGGGACGCGACGCTGTGGCCGTTCGCGACGGCGGGCTTCTTCAAGGTGCGGGAGCGGATTCCACGGCTGCTG
GCGGACATGGGAATTGATTGA

Upstream 100 bases:

>100_bases
ACACGCTGTTCCTCCACCGCAAGATCGGCGGGCTCTATCTGCTCGCGACGCAGCTGCGCGCGAAGGTGGATTGCGCGGCC
TGCGTCGCGCCGTACCGCGC

Downstream 100 bases:

>100_bases
GTGCTGATGCCGTGATGGCTGTGCGGCGGAGTCGTCAAGTCGAGGCGGGGCCGGCGAGCGATCCCGGCGCGCTCGCGCAG
ACAACCGCCGCGCGGCGGCA

Product: putative deoxyribodipyrimidine photo-lyase

Products: NA

Alternate protein names: DNA photolyase; Photoreactivating enzyme [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MTGKLPIATRAAGLARLQTVLPRLGRAYAAGRNHDHGPGRPQAVSGLSPWIRRRLVTEEEVVRAAVAAHGGAADKFVEEV
IWRGYFKGWLERRPQVWTSYLRGRDADLERLDSDGALQARVAAAEAGRTGLACFDAFAQELVATGMLHNHARMWFASLWI
FTLGLPWRLGADFFLRHLLDGDPASNTLGWRWVAGLHTRGKVYAATASNIAQYSAGRFAPRPEDIVIPAQGLEAEEPEGL
PSLRPLRVLIAPRRDVPSLWLITEEDCGLTDFDSDGFTWRGAATLAASQLRSPRPVAEQVAAFEAAALRDGTTRIGLTAA
ALKAVDPAALVACAQDAGATQIVTAEVPQGPLRDWLDAAAPALAAAGLTLAEWRRPWDATLWPFATAGFFKVRERIPRLL
ADMGID

Sequences:

>Translated_406_residues
MTGKLPIATRAAGLARLQTVLPRLGRAYAAGRNHDHGPGRPQAVSGLSPWIRRRLVTEEEVVRAAVAAHGGAADKFVEEV
IWRGYFKGWLERRPQVWTSYLRGRDADLERLDSDGALQARVAAAEAGRTGLACFDAFAQELVATGMLHNHARMWFASLWI
FTLGLPWRLGADFFLRHLLDGDPASNTLGWRWVAGLHTRGKVYAATASNIAQYSAGRFAPRPEDIVIPAQGLEAEEPEGL
PSLRPLRVLIAPRRDVPSLWLITEEDCGLTDFDSDGFTWRGAATLAASQLRSPRPVAEQVAAFEAAALRDGTTRIGLTAA
ALKAVDPAALVACAQDAGATQIVTAEVPQGPLRDWLDAAAPALAAAGLTLAEWRRPWDATLWPFATAGFFKVRERIPRLL
ADMGID
>Mature_405_residues
TGKLPIATRAAGLARLQTVLPRLGRAYAAGRNHDHGPGRPQAVSGLSPWIRRRLVTEEEVVRAAVAAHGGAADKFVEEVI
WRGYFKGWLERRPQVWTSYLRGRDADLERLDSDGALQARVAAAEAGRTGLACFDAFAQELVATGMLHNHARMWFASLWIF
TLGLPWRLGADFFLRHLLDGDPASNTLGWRWVAGLHTRGKVYAATASNIAQYSAGRFAPRPEDIVIPAQGLEAEEPEGLP
SLRPLRVLIAPRRDVPSLWLITEEDCGLTDFDSDGFTWRGAATLAASQLRSPRPVAEQVAAFEAAALRDGTTRIGLTAAA
LKAVDPAALVACAQDAGATQIVTAEVPQGPLRDWLDAAAPALAAAGLTLAEWRRPWDATLWPFATAGFFKVRERIPRLLA
DMGID

Specific function: Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ul

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Escherichia coli, GI1786926, Length=208, Percent_Identity=29.3269230769231, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324962, Length=200, Percent_Identity=29, Blast_Score=73, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002081
- InterPro:   IPR018394
- InterPro:   IPR006050
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: =4.1.99.3 [H]

Molecular weight: Translated: 44070; Mature: 43938

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGKLPIATRAAGLARLQTVLPRLGRAYAAGRNHDHGPGRPQAVSGLSPWIRRRLVTEEE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCHHHHHHHCCHHH
VVRAAVAAHGGAADKFVEEVIWRGYFKGWLERRPQVWTSYLRGRDADLERLDSDGALQAR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHCCCCCCHHHH
VAAAEAGRTGLACFDAFAQELVATGMLHNHARMWFASLWIFTLGLPWRLGADFFLRHLLD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHC
GDPASNTLGWRWVAGLHTRGKVYAATASNIAQYSAGRFAPRPEDIVIPAQGLEAEEPEGL
CCCCCCCCCEEEEECCCCCCEEEEEHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCC
PSLRPLRVLIAPRRDVPSLWLITEEDCGLTDFDSDGFTWRGAATLAASQLRSPRPVAEQV
CCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEECCHHHHHHHHCCCCCHHHHHH
AAFEAAALRDGTTRIGLTAAALKAVDPAALVACAQDAGATQIVTAEVPQGPLRDWLDAAA
HHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHH
PALAAAGLTLAEWRRPWDATLWPFATAGFFKVRERIPRLLADMGID
HHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TGKLPIATRAAGLARLQTVLPRLGRAYAAGRNHDHGPGRPQAVSGLSPWIRRRLVTEEE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCHHHHHHHCCHHH
VVRAAVAAHGGAADKFVEEVIWRGYFKGWLERRPQVWTSYLRGRDADLERLDSDGALQAR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHCCCCCCHHHH
VAAAEAGRTGLACFDAFAQELVATGMLHNHARMWFASLWIFTLGLPWRLGADFFLRHLLD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHC
GDPASNTLGWRWVAGLHTRGKVYAATASNIAQYSAGRFAPRPEDIVIPAQGLEAEEPEGL
CCCCCCCCCEEEEECCCCCCEEEEEHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCC
PSLRPLRVLIAPRRDVPSLWLITEEDCGLTDFDSDGFTWRGAATLAASQLRSPRPVAEQV
CCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCEECCHHHHHHHHCCCCCHHHHHH
AAFEAAALRDGTTRIGLTAAALKAVDPAALVACAQDAGATQIVTAEVPQGPLRDWLDAAA
HHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHH
PALAAAGLTLAEWRRPWDATLWPFATAGFFKVRERIPRLLADMGID
HHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2501760 [H]