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The map label for this gene is atpH [H]

Identifier: 146337561

GI number: 146337561

Start: 426115

End: 426612

Strand: Direct

Name: atpH [H]

Synonym: BRADO0416

Alternate gene names: 146337561

Gene position: 426115-426612 (Clockwise)

Preceding gene: 146337559

Following gene: 146337562

Centisome position: 5.71

GC content: 61.85

Gene sequence:

>498_bases
TTGGCCCGTGACGAAAAGTCCGTCGATGCGGTCAAGGCCGATCTCGACAAATTCAATGCTCTTCTCGACGAGAGTGCCGA
TCTGAAGCGTCTGGTCCGCAGCCCCGTGTTCGGCGCCGATACACAGCTCAAGGCGCTCAACGCGGTGCTCGACAAGGCCG
GCATCGCCGGTGTCGCCGCCAACGTGCTGCGCGTGCTGACCACCAATCGCCGCCTGTTCGCGGTGGCCGACGTGATCCGC
GCCTTCAATGCGCTGGTCGCCAAATACAAGGGTGAAGCCACGGCCGACGTCACCGTCGCCGAGCCGATCTCCGACAAGAA
TCTCGACGCCTTGAAGGCCGCCCTGAAGACGGTGACCGGCAAGGACGTCGCGCTCAACGTGAAAGTCGATCCAGCGATTA
TCGGCGGGCTCGTCGTCAAGCTCGGCAGCCGCATGATCGATAGTTCGCTTCGCACCAAACTCAACTCGATCAAGCACGCG
ATGAAAGAGGCAGGCTGA

Upstream 100 bases:

>100_bases
CTCTTGTGGGTTGGGCACTTATATAAAGAGCGCGCCTGTGGCTGCTGAAGATCCCTCCGTATCCGGTGTGTCCGGTCGTT
ACGCGACGGCCCTGTTTGAA

Downstream 100 bases:

>100_bases
TGGACATCCGCGCCGCGGAAATTTCCGCGATCCTCAAGGACCAGATCAAGAATTTCGGGCAGGAAGCCGAAGTCACCGAA
GTCGGGCAGGTGCTGTCCGT

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MARDEKSVDAVKADLDKFNALLDESADLKRLVRSPVFGADTQLKALNAVLDKAGIAGVAANVLRVLTTNRRLFAVADVIR
AFNALVAKYKGEATADVTVAEPISDKNLDALKAALKTVTGKDVALNVKVDPAIIGGLVVKLGSRMIDSSLRTKLNSIKHA
MKEAG

Sequences:

>Translated_165_residues
MARDEKSVDAVKADLDKFNALLDESADLKRLVRSPVFGADTQLKALNAVLDKAGIAGVAANVLRVLTTNRRLFAVADVIR
AFNALVAKYKGEATADVTVAEPISDKNLDALKAALKTVTGKDVALNVKVDPAIIGGLVVKLGSRMIDSSLRTKLNSIKHA
MKEAG
>Mature_164_residues
ARDEKSVDAVKADLDKFNALLDESADLKRLVRSPVFGADTQLKALNAVLDKAGIAGVAANVLRVLTTNRRLFAVADVIRA
FNALVAKYKGEATADVTVAEPISDKNLDALKAALKTVTGKDVALNVKVDPAIIGGLVVKLGSRMIDSSLRTKLNSIKHAM
KEAG

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction [H]

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family [H]

Homologues:

Organism=Homo sapiens, GI4502303, Length=164, Percent_Identity=28.6585365853659, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1790173, Length=97, Percent_Identity=32.9896907216495, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71984717, Length=165, Percent_Identity=27.2727272727273, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71984710, Length=165, Percent_Identity=27.2727272727273, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320504, Length=167, Percent_Identity=28.7425149700599, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24647054, Length=149, Percent_Identity=31.5436241610738, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24647056, Length=112, Percent_Identity=33.9285714285714, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000711
- InterPro:   IPR020781 [H]

Pfam domain/function: PF00213 OSCP [H]

EC number: 3.6.3.14

Molecular weight: Translated: 17467; Mature: 17335

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARDEKSVDAVKADLDKFNALLDESADLKRLVRSPVFGADTQLKALNAVLDKAGIAGVAA
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
NVLRVLTTNRRLFAVADVIRAFNALVAKYKGEATADVTVAEPISDKNLDALKAALKTVTG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHCC
KDVALNVKVDPAIIGGLVVKLGSRMIDSSLRTKLNSIKHAMKEAG
CCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARDEKSVDAVKADLDKFNALLDESADLKRLVRSPVFGADTQLKALNAVLDKAGIAGVAA
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
NVLRVLTTNRRLFAVADVIRAFNALVAKYKGEATADVTVAEPISDKNLDALKAALKTVTG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHCC
KDVALNVKVDPAIIGGLVVKLGSRMIDSSLRTKLNSIKHAMKEAG
CCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA