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The map label for this gene is yleA [C]

Identifier: 146337530

GI number: 146337530

Start: 389250

End: 390581

Strand: Direct

Name: yleA [C]

Synonym: BRADO0384

Alternate gene names: 146337530

Gene position: 389250-390581 (Clockwise)

Preceding gene: 146337529

Following gene: 146337532

Centisome position: 5.22

GC content: 67.12

Gene sequence:

>1332_bases
ATGAGCGTCGATGTCGTCACCTTCGGCTGCCGGCTCAACGCGTTCGAGTCCGAGCTGATCGCGCGCCATGTCGAGGCAGC
GGGGGCGGACGACACCATCGTCATCAACAGCTGCGCTGTCACCAACGAGGCCGTGGCGCAGGCGCGGCAATCGATCCGCA
AATTGAAGCGCGAGCGCCCTTACGCGCGCATCGTCGTGACTGGTTGCGCGGCGCAGACGCAGGCCGACATGTTCGCTGCG
ATGCCTGAAGTCGATCGCGTGATCGGCAATGACGACAAGCTGCGGCCGGACGCCTGGCGCGCGACTACGCAGGTGCTGGC
TGCGCCCCGCTTCGGCATCGATGCGACCGAAAAGGTCGCCGTCTCCGACATCATGGCCGTCACCGAGATGGCGCCGCATC
TGGTCGACGGCTTCCAGCGCGGCCTGCCGCGGGTGTTCGTCCAGGTGCAGAACGGCTGCGACCATCGCTGCACCTTCTGC
ATCATCCCCTACGGCCGCGGCAATTCACGCTCGGTGCCGATGGGGGCGGTGGTCGATCAGGTGCGAACGCTGGCTGAGCG
CGGCCATGCTGAGATCGTGCTGACCGGCGTCGATCTCACCAGCTACGGCGCCGACCTGCCCGGCACGCCGAAGCTCGGCC
TGCTGGTGAAACAGATCCTGCGCCACGTGCCGGAGCTGAAACGGTTGCGCATCTCCTCGATCGATTCGATCGAGGCCGAT
GCCGACCTGCTCGATGCGCTCGCCGACGATGCCCGGCTGATGCCGCACCTGCATCTGTCATTGCAGGCCGGCGACGACCT
GATCCTGAAGCGTATGAAGCGGCGGCATGTGCGCGCGGACGCGATCGCGTTCTGCGACCAGGTGCGTCGGCTGCGGCCGG
ACATCGCGCTCGGCGCTGATCTGATCGCAGGCTTTCCAACCGAGACGGAGGAGATGTTTACGCGCTCGCTCGACCTCGTC
GAGGCATGCGGCCTGACGCTCCTGCACGTCTTTCCCTATTCGCCGCGCCCGGGCACGCCGGCCGCGCGCATGCCGCAGGT
GGATGGCGCCGTCATCCGTGATCGCGCGCGTCGGCTGCGCGCAGTGGGGGAGGCTGCGTTGCGGCGGCGGCTGGATGCCG
AGATCGGCTGCGCGCGTGAAGTTCTTATCGAGAGTGCGACGCAGGGCAGGACGGAGCATTATCTGCCGGTGTCAGTCACG
GGTGCCGAGCCGGGCTCAGTGCAGCGGCTGGTGATCGCCGGCCATGATGGCGGAAAACTGTCAGCCCCACCCTCGGTGTC
ATCGCCCGGCTTGACCGGGCGATCCAGTACGCCGCGGCCTCTTGGTCAATAA

Upstream 100 bases:

>100_bases
CGATCGAGTGGCGCGAGCGCGACGACCACGTGTTGATGACGGGCACCGCGACGTTCGAGTTCGAGGGCCGGTTTGAGCCA
GCGCTGTTCGCCAGCGTCGC

Downstream 100 bases:

>100_bases
TAACCGCCTCTGGAATACTGGATCGCCCGGTCGAGCCGGGCGATGACAGCTGTGGTGTGGGCGAGAGTGCAGGGTCTCAC
TTGCGTCCGAGACGCTTCAC

Product: putative MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSVDVVTFGCRLNAFESELIARHVEAAGADDTIVINSCAVTNEAVAQARQSIRKLKRERPYARIVVTGCAAQTQADMFAA
MPEVDRVIGNDDKLRPDAWRATTQVLAAPRFGIDATEKVAVSDIMAVTEMAPHLVDGFQRGLPRVFVQVQNGCDHRCTFC
IIPYGRGNSRSVPMGAVVDQVRTLAERGHAEIVLTGVDLTSYGADLPGTPKLGLLVKQILRHVPELKRLRISSIDSIEAD
ADLLDALADDARLMPHLHLSLQAGDDLILKRMKRRHVRADAIAFCDQVRRLRPDIALGADLIAGFPTETEEMFTRSLDLV
EACGLTLLHVFPYSPRPGTPAARMPQVDGAVIRDRARRLRAVGEAALRRRLDAEIGCAREVLIESATQGRTEHYLPVSVT
GAEPGSVQRLVIAGHDGGKLSAPPSVSSPGLTGRSSTPRPLGQ

Sequences:

>Translated_443_residues
MSVDVVTFGCRLNAFESELIARHVEAAGADDTIVINSCAVTNEAVAQARQSIRKLKRERPYARIVVTGCAAQTQADMFAA
MPEVDRVIGNDDKLRPDAWRATTQVLAAPRFGIDATEKVAVSDIMAVTEMAPHLVDGFQRGLPRVFVQVQNGCDHRCTFC
IIPYGRGNSRSVPMGAVVDQVRTLAERGHAEIVLTGVDLTSYGADLPGTPKLGLLVKQILRHVPELKRLRISSIDSIEAD
ADLLDALADDARLMPHLHLSLQAGDDLILKRMKRRHVRADAIAFCDQVRRLRPDIALGADLIAGFPTETEEMFTRSLDLV
EACGLTLLHVFPYSPRPGTPAARMPQVDGAVIRDRARRLRAVGEAALRRRLDAEIGCAREVLIESATQGRTEHYLPVSVT
GAEPGSVQRLVIAGHDGGKLSAPPSVSSPGLTGRSSTPRPLGQ
>Mature_442_residues
SVDVVTFGCRLNAFESELIARHVEAAGADDTIVINSCAVTNEAVAQARQSIRKLKRERPYARIVVTGCAAQTQADMFAAM
PEVDRVIGNDDKLRPDAWRATTQVLAAPRFGIDATEKVAVSDIMAVTEMAPHLVDGFQRGLPRVFVQVQNGCDHRCTFCI
IPYGRGNSRSVPMGAVVDQVRTLAERGHAEIVLTGVDLTSYGADLPGTPKLGLLVKQILRHVPELKRLRISSIDSIEADA
DLLDALADDARLMPHLHLSLQAGDDLILKRMKRRHVRADAIAFCDQVRRLRPDIALGADLIAGFPTETEEMFTRSLDLVE
ACGLTLLHVFPYSPRPGTPAARMPQVDGAVIRDRARRLRAVGEAALRRRLDAEIGCAREVLIESATQGRTEHYLPVSVTG
AEPGSVQRLVIAGHDGGKLSAPPSVSSPGLTGRSSTPRPLGQ

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=405, Percent_Identity=27.9012345679012, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI28872782, Length=454, Percent_Identity=24.8898678414097, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI28872784, Length=454, Percent_Identity=24.8898678414097, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1786882, Length=434, Percent_Identity=26.036866359447, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1787057, Length=403, Percent_Identity=27.7915632754342, Blast_Score=133, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17553146, Length=473, Percent_Identity=25.5813953488372, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71996771, Length=248, Percent_Identity=29.8387096774194, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI21356207, Length=437, Percent_Identity=26.0869565217391, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI19922432, Length=385, Percent_Identity=27.5324675324675, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47995; Mature: 47864

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDVVTFGCRLNAFESELIARHVEAAGADDTIVINSCAVTNEAVAQARQSIRKLKRERP
CCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCC
YARIVVTGCAAQTQADMFAAMPEVDRVIGNDDKLRPDAWRATTQVLAAPRFGIDATEKVA
CEEEEEECCCCHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHH
VSDIMAVTEMAPHLVDGFQRGLPRVFVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVDQ
HHHHHHHHHHHHHHHHHHHHCHHHEEHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHH
VRTLAERGHAEIVLTGVDLTSYGADLPGTPKLGLLVKQILRHVPELKRLRISSIDSIEAD
HHHHHHCCCCEEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCH
ADLLDALADDARLMPHLHLSLQAGDDLILKRMKRRHVRADAIAFCDQVRRLRPDIALGAD
HHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHH
LIAGFPTETEEMFTRSLDLVEACGLTLLHVFPYSPRPGTPAARMPQVDGAVIRDRARRLR
HHCCCCCCHHHHHHHHHHHHHHHCHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AVGEAALRRRLDAEIGCAREVLIESATQGRTEHYLPVSVTGAEPGSVQRLVIAGHDGGKL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCC
SAPPSVSSPGLTGRSSTPRPLGQ
CCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVDVVTFGCRLNAFESELIARHVEAAGADDTIVINSCAVTNEAVAQARQSIRKLKRERP
CCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCC
YARIVVTGCAAQTQADMFAAMPEVDRVIGNDDKLRPDAWRATTQVLAAPRFGIDATEKVA
CEEEEEECCCCHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHH
VSDIMAVTEMAPHLVDGFQRGLPRVFVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVDQ
HHHHHHHHHHHHHHHHHHHHCHHHEEHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHH
VRTLAERGHAEIVLTGVDLTSYGADLPGTPKLGLLVKQILRHVPELKRLRISSIDSIEAD
HHHHHHCCCCEEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCH
ADLLDALADDARLMPHLHLSLQAGDDLILKRMKRRHVRADAIAFCDQVRRLRPDIALGAD
HHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHH
LIAGFPTETEEMFTRSLDLVEACGLTLLHVFPYSPRPGTPAARMPQVDGAVIRDRARRLR
HHCCCCCCHHHHHHHHHHHHHHHCHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AVGEAALRRRLDAEIGCAREVLIESATQGRTEHYLPVSVTGAEPGSVQRLVIAGHDGGKL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCC
SAPPSVSSPGLTGRSSTPRPLGQ
CCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]