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The map label for this gene is asd [H]

Identifier: 146337507

GI number: 146337507

Start: 369716

End: 370750

Strand: Direct

Name: asd [H]

Synonym: BRADO0358

Alternate gene names: 146337507

Gene position: 369716-370750 (Clockwise)

Preceding gene: 146337504

Following gene: 146337508

Centisome position: 4.96

GC content: 62.51

Gene sequence:

>1035_bases
ATGGGTTACAAAGTCGCAGTGGTCGGCGCGACCGGCAATGTCGGGCGGGAAATGCTCAACATTCTCGACGAGCGGAAGTT
TCCCGCCGACGAGGTCGTGGCGCTCGCTTCACGCCGCAGCGTCGGCGTCGAGGTGTCCTATGGCGATCGCACGCTGAAGG
TCAAAGCGCTCGAGCACTACGATTTTGCCGATGTCGATATCTGCCTGATGTCGGCGGGCGGCACGGTCTCGAAGGAATGG
TCGCCGAAGATCGGCGCCGCAGGCGCCGTCGTCATCGACAACTCCTCGGCTTGGCGCATGGATCCGGACGTGCCGCTGAT
CGTGCCGGAGGTGAACGCCGATGCGGCCGCAGGGTTCAACAAGAAGAACATCATCGCCAACCCGAACTGCTCGACCGCGC
AGCTCGTCGTCGCGCTGAAGCCGCTGCACGACAAGGCGCATATCACGCGCGTCGTCGTTTCGACCTATCAGTCGGTGTCC
GGCGCCGGCAAGGACGCGATGGACGAATTGTTCTCGCAGACCAAGGCCGTCTACACCAATGACGAGCTGGTCGCGAAGAA
GTTCCCCAAGCGCATCGCCTTCAACGTCATCCCGCACATCGACGTCTTCATGGAAGACGGCTTCACCAAGGAAGAGTGGA
AGATGATGGCGGAGACCAAGAAGATCCTGGATCCGAAGATCAAGCTGACCGCGACCTGCGTGCGTGTGCCGGTGTTCGTC
GGCCATTCCGAAGCCGTCAATGTCGAGTTTGAGCAGCCGATCACGGCGGACGAGGCCCGCGAGATTCTGCGCCGCGCGCC
GGGCTGCCTCGTCATCGACAAGCAGGAGCCGGGCGGCTACGCGACTCCTTATGAGGCCGCCGGCGAGGACGCGACCTATA
TCAGCCGCATCCGCGAGGATGCCACGGTCGAGAACGGCCTCGCCTTCTGGTGCGTGTCGGACAATCTGCGCAAGGGCGCG
GCGCTGAATGCGATCCAGATTGCGGAAGTGCTGATCAACCGCAAGCTGATCACCGCCAAGAAGAAGGCGGCGTAA

Upstream 100 bases:

>100_bases
CGTGGTAACGTTGTGTCAGGGACGTTTCTCGCATAGAAGCGCTGCCGCTTCCGTTTCCGCTGAGATGAGCGGTCGGCCAT
ATTTCTTCGGAGAGTGAACG

Downstream 100 bases:

>100_bases
CGGACAACCGGTCCGCTCCCGCACATGGAGACCGAAGCCTTGCGTTCGAGTGTCTCAACGTCGTCATGGCTGGGCTGGTC
CTCCACGTCGGTCGGCATGA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MGYKVAVVGATGNVGREMLNILDERKFPADEVVALASRRSVGVEVSYGDRTLKVKALEHYDFADVDICLMSAGGTVSKEW
SPKIGAAGAVVIDNSSAWRMDPDVPLIVPEVNADAAAGFNKKNIIANPNCSTAQLVVALKPLHDKAHITRVVVSTYQSVS
GAGKDAMDELFSQTKAVYTNDELVAKKFPKRIAFNVIPHIDVFMEDGFTKEEWKMMAETKKILDPKIKLTATCVRVPVFV
GHSEAVNVEFEQPITADEAREILRRAPGCLVIDKQEPGGYATPYEAAGEDATYISRIREDATVENGLAFWCVSDNLRKGA
ALNAIQIAEVLINRKLITAKKKAA

Sequences:

>Translated_344_residues
MGYKVAVVGATGNVGREMLNILDERKFPADEVVALASRRSVGVEVSYGDRTLKVKALEHYDFADVDICLMSAGGTVSKEW
SPKIGAAGAVVIDNSSAWRMDPDVPLIVPEVNADAAAGFNKKNIIANPNCSTAQLVVALKPLHDKAHITRVVVSTYQSVS
GAGKDAMDELFSQTKAVYTNDELVAKKFPKRIAFNVIPHIDVFMEDGFTKEEWKMMAETKKILDPKIKLTATCVRVPVFV
GHSEAVNVEFEQPITADEAREILRRAPGCLVIDKQEPGGYATPYEAAGEDATYISRIREDATVENGLAFWCVSDNLRKGA
ALNAIQIAEVLINRKLITAKKKAA
>Mature_343_residues
GYKVAVVGATGNVGREMLNILDERKFPADEVVALASRRSVGVEVSYGDRTLKVKALEHYDFADVDICLMSAGGTVSKEWS
PKIGAAGAVVIDNSSAWRMDPDVPLIVPEVNADAAAGFNKKNIIANPNCSTAQLVVALKPLHDKAHITRVVVSTYQSVSG
AGKDAMDELFSQTKAVYTNDELVAKKFPKRIAFNVIPHIDVFMEDGFTKEEWKMMAETKKILDPKIKLTATCVRVPVFVG
HSEAVNVEFEQPITADEAREILRRAPGCLVIDKQEPGGYATPYEAAGEDATYISRIREDATVENGLAFWCVSDNLRKGAA
LNAIQIAEVLINRKLITAKKKAA

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=338, Percent_Identity=34.0236686390533, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI1789841, Length=354, Percent_Identity=27.1186440677966, Blast_Score=104, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6320362, Length=398, Percent_Identity=30.9045226130653, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37437; Mature: 37306

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYKVAVVGATGNVGREMLNILDERKFPADEVVALASRRSVGVEVSYGDRTLKVKALEHY
CCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCEEEEEEEECCC
DFADVDICLMSAGGTVSKEWSPKIGAAGAVVIDNSSAWRMDPDVPLIVPEVNADAAAGFN
CCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCEEEECCCCHHHCCCC
KKNIIANPNCSTAQLVVALKPLHDKAHITRVVVSTYQSVSGAGKDAMDELFSQTKAVYTN
CCCEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCEEECC
DELVAKKFPKRIAFNVIPHIDVFMEDGFTKEEWKMMAETKKILDPKIKLTATCVRVPVFV
CHHHHHHCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEE
GHSEAVNVEFEQPITADEAREILRRAPGCLVIDKQEPGGYATPYEAAGEDATYISRIRED
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHC
ATVENGLAFWCVSDNLRKGAALNAIQIAEVLINRKLITAKKKAA
CHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCHHCCCCCCCC
>Mature Secondary Structure 
GYKVAVVGATGNVGREMLNILDERKFPADEVVALASRRSVGVEVSYGDRTLKVKALEHY
CEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCEEEEEEEECCC
DFADVDICLMSAGGTVSKEWSPKIGAAGAVVIDNSSAWRMDPDVPLIVPEVNADAAAGFN
CCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCEEEECCCCHHHCCCC
KKNIIANPNCSTAQLVVALKPLHDKAHITRVVVSTYQSVSGAGKDAMDELFSQTKAVYTN
CCCEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCEEECC
DELVAKKFPKRIAFNVIPHIDVFMEDGFTKEEWKMMAETKKILDPKIKLTATCVRVPVFV
CHHHHHHCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEE
GHSEAVNVEFEQPITADEAREILRRAPGCLVIDKQEPGGYATPYEAAGEDATYISRIRED
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHC
ATVENGLAFWCVSDNLRKGAALNAIQIAEVLINRKLITAKKKAA
CHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]