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The map label for this gene is fabA [H]

Identifier: 146337237

GI number: 146337237

Start: 73336

End: 73857

Strand: Reverse

Name: fabA [H]

Synonym: BRADO0063

Alternate gene names: 146337237

Gene position: 73857-73336 (Counterclockwise)

Preceding gene: 146337239

Following gene: 146337236

Centisome position: 0.99

GC content: 64.18

Gene sequence:

>522_bases
ATGCTGGATCGGCGCGGCAGTTATGAATACGAGGACCTGCTGGCCTGCGGCCGTGGGGAGCTGTTCGGTCCAGGCAATGC
GCAGCTGCCGTTGCCGCCGATGCTGATGTTCGATCGCATCGTCGAGATCTCCGAGACCGGTGGCGAGTTCGGCAAGGGCG
TCGTGCGCGCCGAGCTCGATGTGAAGCCGGATCTCTGGTTCTTCGGCTGCCATTTCAAGAACGATCCGGTCATGCCGGGC
TGCCTCGGTCTGGACGCGATGTGGCAGATGGTCGGCTTCTTCCTCGGCTGGACAGGCGGCGCAGGACGCGGCCGCGCGCT
CGGTCTCGGCGACCTCAAATTCTCCGGCCAGGTTCTGCCGACCGCGAGCAAGGTCGTCTACAACGTCGACATCAAGCGCG
TGATGCGCTCGAAGCTGGTGCTCGGCATCGCCGACGGGTGGCTTTCGATGGACGGCGACATTATCTATCGCGCCAAGGAT
CTGAAGGTCGGGCTGTTCAAGCAGGGCGCCGCGCCGTCTTGA

Upstream 100 bases:

>100_bases
TGGCCGAACGGCGAAACGGCGCATCAGCGGGTCGGCGCGTGAAGGGGCATGTCGCGCGCCACATTTTCCACCGGGGATCG
TTGAGAAGGGCTCATCAAGC

Downstream 100 bases:

>100_bases
ACCGGCGGACCGCGACCACAGACAGTGCAGCGAGCACCACTGCAACAGAACACATGAGCAAGGCGAGGCGGACATCATGA
GGCGGGTCGTCATCACGGGC

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MLDRRGSYEYEDLLACGRGELFGPGNAQLPLPPMLMFDRIVEISETGGEFGKGVVRAELDVKPDLWFFGCHFKNDPVMPG
CLGLDAMWQMVGFFLGWTGGAGRGRALGLGDLKFSGQVLPTASKVVYNVDIKRVMRSKLVLGIADGWLSMDGDIIYRAKD
LKVGLFKQGAAPS

Sequences:

>Translated_173_residues
MLDRRGSYEYEDLLACGRGELFGPGNAQLPLPPMLMFDRIVEISETGGEFGKGVVRAELDVKPDLWFFGCHFKNDPVMPG
CLGLDAMWQMVGFFLGWTGGAGRGRALGLGDLKFSGQVLPTASKVVYNVDIKRVMRSKLVLGIADGWLSMDGDIIYRAKD
LKVGLFKQGAAPS
>Mature_173_residues
MLDRRGSYEYEDLLACGRGELFGPGNAQLPLPPMLMFDRIVEISETGGEFGKGVVRAELDVKPDLWFFGCHFKNDPVMPG
CLGLDAMWQMVGFFLGWTGGAGRGRALGLGDLKFSGQVLPTASKVVYNVDIKRVMRSKLVLGIADGWLSMDGDIIYRAKD
LKVGLFKQGAAPS

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=171, Percent_Identity=64.9122807017544, Blast_Score=238, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 18878; Mature: 18878

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDRRGSYEYEDLLACGRGELFGPGNAQLPLPPMLMFDRIVEISETGGEFGKGVVRAELD
CCCCCCCCCHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEC
VKPDLWFFGCHFKNDPVMPGCLGLDAMWQMVGFFLGWTGGAGRGRALGLGDLKFSGQVLP
CCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCEECCEECC
TASKVVYNVDIKRVMRSKLVLGIADGWLSMDGDIIYRAKDLKVGLFKQGAAPS
CCCEEEEEHHHHHHHHHHEEEEEECCEEECCCCEEEEECCCEEEEECCCCCCC
>Mature Secondary Structure
MLDRRGSYEYEDLLACGRGELFGPGNAQLPLPPMLMFDRIVEISETGGEFGKGVVRAELD
CCCCCCCCCHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEC
VKPDLWFFGCHFKNDPVMPGCLGLDAMWQMVGFFLGWTGGAGRGRALGLGDLKFSGQVLP
CCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCEECCEECC
TASKVVYNVDIKRVMRSKLVLGIADGWLSMDGDIIYRAKDLKVGLFKQGAAPS
CCCEEEEEHHHHHHHHHHEEEEEECCEEECCCCEEEEECCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA