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The map label for this gene is cph1 [H]

Identifier: 146301562

GI number: 146301562

Start: 4531186

End: 4532682

Strand: Direct

Name: cph1 [H]

Synonym: Fjoh_3823

Alternate gene names: 146301562

Gene position: 4531186-4532682 (Clockwise)

Preceding gene: 146301561

Following gene: 146301565

Centisome position: 74.32

GC content: 38.34

Gene sequence:

>1497_bases
ATGATGGATCTTCCAGAATCAATAAGAGAAAAGGTTTTACGTGATGTTATAGATACAGCGCCTTTTCCAATCGGAGTATA
CACAGGAGATAAAATGAAAATTGTACTGGCAAACCAGTCCATGATTAAAACCTATGGAAAAGGACCTGATGTGATAGGGA
CAAACTATACAGAAATTCTTCCTGAACTTGAAAACCAGCAGATATTTGATCAGCTCCGCGAGGTGCTGCATACAGGAAAA
TCATATGAAGCAAAAAATGCACGAGTTGACATTGTTGTAAATGGCAAATTGAAACCGCACTATTTCAATTACAACTTTAC
GCCCATTTTCGGCGCGGAAGGAGAAGTCTACGGCGTAATGAATACGGCTGCTGAAGTAACAGAACTTAATGTTGCCCGGC
AGCAGACTATAGAAATTGAAAAGAAATTAAGACTAGCTGTTGAATCCTCGCAGCTTGGAATATTCGAGATAGATATCAAA
AAAGGTCTTATGAGAGGATCAAAACGTTTTACAAACTTTTTTGGACTGGAAAAGCGTGAGTTTACACTCAATACTTTGGT
GTCTTTTATCCATCCGGAAGATATAGCGTTATGGCACAATGCGCTCGAAACACTCTCAGAAACAGCAGACTTAAACTGTG
AGCTGAGGGTGATAAACAATAAAAAACTGCAATGGATACGATTTTCCGGTTCACTATCAGAGAGTGATGATAAGGAGAAT
ACTATCGTAGGAATAGCTCAGGACATTACTGTACAGAAAGAAAATGCCCAGGAGCTTATGCAGCTGGTGGAACAGCGCAC
ACTTGAACTCAGACGCTCTAATGATGACCTGAAACAGTTTGGGCACGTGATCAGCCATGACTTAAAAGAGCCGGTTCGCA
AATTGCTATTGTTCTCCAATATTCTTAAAGAAGATTTAGATAATGATAAAAAACCGAGAATGAGCCAGTATGCCCATAAA
ATCAATAAAAGCGCTGCACGTCTCACAGAAATGATTGACTCTATATTAAACTATTCCTCTGCCGGAAGTCCGGATTTGAA
CGAAGTTGTCGACCTGAACCATATTATTGAAAATATAAAGGAAGATCTTGAAATAAAAATTCTCGAAAAACATGCAGTCA
TTGAGCACAAAAAAATGCCTCTTTTAAACGGGTCAAAAATTTTATTCCATCAGCTGTTTTATAACCTTATTGCCAACTCC
CTGAAGTTTTCTCGTGATAATTTTGATTCTCATATCAAAATTGAATGTAGTTTTGACTCTGAAAAACTGCTAATTACAAT
AACGGACAACGGTATAGGGATTTCCATCGAAAATTCCCTGAGAATCTTCAATGTCTTTGAGAGGCTGCATTCGAAAGATG
AGTATGAAGGAACCGGGTTAGGACTGGCGCTCTGCAAAAAAATAGTTGAACGCCATAACGGGAAAATGATGTATGTTAAA
CCTGAAACTACAGGTGCTGTTTTTGAAATTATCTTACCGGCATCAATTTTACACTAA

Upstream 100 bases:

>100_bases
ACTGATCAGCAAAGCGATGTCTCTGGTATCTCACACAGATGTACGGCAGCCTGCCTTTGAGAACTTTCACATTAAAATTT
AATTATTATTTTTTGCCAGC

Downstream 100 bases:

>100_bases
TGTAATTTTACATGTAAAATTACAGACTAAAGCAGCTCATTACGAATTGCTTTTGGTGCGATTAAAATCAGTAATCATAT
AGAGACATACCGCAAAAGCT

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MMDLPESIREKVLRDVIDTAPFPIGVYTGDKMKIVLANQSMIKTYGKGPDVIGTNYTEILPELENQQIFDQLREVLHTGK
SYEAKNARVDIVVNGKLKPHYFNYNFTPIFGAEGEVYGVMNTAAEVTELNVARQQTIEIEKKLRLAVESSQLGIFEIDIK
KGLMRGSKRFTNFFGLEKREFTLNTLVSFIHPEDIALWHNALETLSETADLNCELRVINNKKLQWIRFSGSLSESDDKEN
TIVGIAQDITVQKENAQELMQLVEQRTLELRRSNDDLKQFGHVISHDLKEPVRKLLLFSNILKEDLDNDKKPRMSQYAHK
INKSAARLTEMIDSILNYSSAGSPDLNEVVDLNHIIENIKEDLEIKILEKHAVIEHKKMPLLNGSKILFHQLFYNLIANS
LKFSRDNFDSHIKIECSFDSEKLLITITDNGIGISIENSLRIFNVFERLHSKDEYEGTGLGLALCKKIVERHNGKMMYVK
PETTGAVFEIILPASILH

Sequences:

>Translated_498_residues
MMDLPESIREKVLRDVIDTAPFPIGVYTGDKMKIVLANQSMIKTYGKGPDVIGTNYTEILPELENQQIFDQLREVLHTGK
SYEAKNARVDIVVNGKLKPHYFNYNFTPIFGAEGEVYGVMNTAAEVTELNVARQQTIEIEKKLRLAVESSQLGIFEIDIK
KGLMRGSKRFTNFFGLEKREFTLNTLVSFIHPEDIALWHNALETLSETADLNCELRVINNKKLQWIRFSGSLSESDDKEN
TIVGIAQDITVQKENAQELMQLVEQRTLELRRSNDDLKQFGHVISHDLKEPVRKLLLFSNILKEDLDNDKKPRMSQYAHK
INKSAARLTEMIDSILNYSSAGSPDLNEVVDLNHIIENIKEDLEIKILEKHAVIEHKKMPLLNGSKILFHQLFYNLIANS
LKFSRDNFDSHIKIECSFDSEKLLITITDNGIGISIENSLRIFNVFERLHSKDEYEGTGLGLALCKKIVERHNGKMMYVK
PETTGAVFEIILPASILH
>Mature_498_residues
MMDLPESIREKVLRDVIDTAPFPIGVYTGDKMKIVLANQSMIKTYGKGPDVIGTNYTEILPELENQQIFDQLREVLHTGK
SYEAKNARVDIVVNGKLKPHYFNYNFTPIFGAEGEVYGVMNTAAEVTELNVARQQTIEIEKKLRLAVESSQLGIFEIDIK
KGLMRGSKRFTNFFGLEKREFTLNTLVSFIHPEDIALWHNALETLSETADLNCELRVINNKKLQWIRFSGSLSESDDKEN
TIVGIAQDITVQKENAQELMQLVEQRTLELRRSNDDLKQFGHVISHDLKEPVRKLLLFSNILKEDLDNDKKPRMSQYAHK
INKSAARLTEMIDSILNYSSAGSPDLNEVVDLNHIIENIKEDLEIKILEKHAVIEHKKMPLLNGSKILFHQLFYNLIANS
LKFSRDNFDSHIKIECSFDSEKLLITITDNGIGISIENSLRIFNVFERLHSKDEYEGTGLGLALCKKIVERHNGKMMYVK
PETTGAVFEIILPASILH

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=214, Percent_Identity=26.6355140186916, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693157, Length=271, Percent_Identity=26.5682656826568, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790346, Length=222, Percent_Identity=27.9279279279279, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=227, Percent_Identity=24.6696035242291, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI48994928, Length=270, Percent_Identity=22.962962962963, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788549, Length=258, Percent_Identity=23.2558139534884, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=23.5294117647059, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56833; Mature: 56833

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDLPESIREKVLRDVIDTAPFPIGVYTGDKMKIVLANQSMIKTYGKGPDVIGTNYTEIL
CCCCCHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEECCHHHHHCCCCCCCCCCCHHHHH
PELENQQIFDQLREVLHTGKSYEAKNARVDIVVNGKLKPHYFNYNFTPIFGAEGEVYGVM
CCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEECCCCCEEECCCCCEEEEH
NTAAEVTELNVARQQTIEIEKKLRLAVESSQLGIFEIDIKKGLMRGSKRFTNFFGLEKRE
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHH
FTLNTLVSFIHPEDIALWHNALETLSETADLNCELRVINNKKLQWIRFSGSLSESDDKEN
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCCCCC
TIVGIAQDITVQKENAQELMQLVEQRTLELRRSNDDLKQFGHVISHDLKEPVRKLLLFSN
EEEEEECCCEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ILKEDLDNDKKPRMSQYAHKINKSAARLTEMIDSILNYSSAGSPDLNEVVDLNHIIENIK
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
EDLEIKILEKHAVIEHKKMPLLNGSKILFHQLFYNLIANSLKFSRDNFDSHIKIECSFDS
HCCEEEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCC
EKLLITITDNGIGISIENSLRIFNVFERLHSKDEYEGTGLGLALCKKIVERHNGKMMYVK
CEEEEEEECCCEEEEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEC
PETTGAVFEIILPASILH
CCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MMDLPESIREKVLRDVIDTAPFPIGVYTGDKMKIVLANQSMIKTYGKGPDVIGTNYTEIL
CCCCCHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEECCHHHHHCCCCCCCCCCCHHHHH
PELENQQIFDQLREVLHTGKSYEAKNARVDIVVNGKLKPHYFNYNFTPIFGAEGEVYGVM
CCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEECCCCCEEECCCCCEEEEH
NTAAEVTELNVARQQTIEIEKKLRLAVESSQLGIFEIDIKKGLMRGSKRFTNFFGLEKRE
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHH
FTLNTLVSFIHPEDIALWHNALETLSETADLNCELRVINNKKLQWIRFSGSLSESDDKEN
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCCCCC
TIVGIAQDITVQKENAQELMQLVEQRTLELRRSNDDLKQFGHVISHDLKEPVRKLLLFSN
EEEEEECCCEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ILKEDLDNDKKPRMSQYAHKINKSAARLTEMIDSILNYSSAGSPDLNEVVDLNHIIENIK
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
EDLEIKILEKHAVIEHKKMPLLNGSKILFHQLFYNLIANSLKFSRDNFDSHIKIECSFDS
HCCEEEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCC
EKLLITITDNGIGISIENSLRIFNVFERLHSKDEYEGTGLGLALCKKIVERHNGKMMYVK
CEEEEEEECCCEEEEECCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEC
PETTGAVFEIILPASILH
CCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]