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The map label for this gene is aphA [H]

Identifier: 146301528

GI number: 146301528

Start: 4489859

End: 4492345

Strand: Reverse

Name: aphA [H]

Synonym: Fjoh_3789

Alternate gene names: 146301528

Gene position: 4492345-4489859 (Counterclockwise)

Preceding gene: 146301532

Following gene: 146301526

Centisome position: 73.68

GC content: 44.15

Gene sequence:

>2487_bases
ATGACCGTGAACACAGAAGACCAATTGCCTGAGTATTCATTTTTGAAAAAGGGAGGTGAAGCCGGATCCATTTTACTGCA
AAAAGACTGGAGCATCACAGCTCTGGGCACTCCGAATAACTGGACGGAAAGCCTTAGAACCGCTGCTGGAATCATGTTTT
CTTCACGTGTGCCCATGTTCTTAGTCTGGGGTAAAGAAAAAACTCTTTTGTACAATGACCCTTTTATTATATTCCTTAGA
GAAAATAATAAACATCCTTATGCATTAGGAAAAACACTAACAGATGCCCTGCCCCAGGATTGGCTGGTGGTCTGCGATGC
GGTGCAGGGAATTATTGAAAAGGGAATTTTAAAATCCGAATCCAACATTACTGCCACAGTAATGAGAAACGGATTGCAGC
AGAAAGTATATCTTACTGCAGGTTACAGTGTCATAACAAATAAAAACGATACCATTGAAGGCGTTTTTGTGACCTGTCTG
GAAAATTCTGCCGTTATCCCGGATATGATCGGTTCAAGTTCTGTCCGTTCGCAGCTTAACAGCCTGCTGATGCAGTCGAA
TGCAGGAATTGCACAGGCCAATATCCAGGGGCGCGTTGTGGAAGTGAATGACCGCTACTGCCAGATGCTAGGGTACAGCC
GTGAAGAAATCCTGCTGATGAATTTAGGTGAGCTCACTCATCCGGATGATTTGCAGCGAAATATGCTGTTGTTGCAGGAC
TGCATTGAAAACGGAAAAGATTTTTTAATTACCAAACGTTATATATGCCGTGACGGATCCGTAATCTGGGTTAATAATAG
CATTTCAGTTGTTATGGACCAGCTGGGTGAAAAGTACATAACGGCCATAGCTATCGATATTACTGATCAAAAAGAAAAGG
AGGAAAAACTGCTGGCTAGTGAAGCTCATTTACAGCTTTTAAGAGATACAGTGCCGGCCATGATTTTTTATCTTGACCAA
GAGCAGCGCTATGTCACTTACAACACTGTTTTCAAAGAGTGGTTTTCCATTGAAGGCGATCAGGCCGTTGGGAAAACTGT
TCGGGAATTTTTGGGTGAAGCCGCTTATGCAAAAACGCTTCCTCATCTTAAAATAGCTTATGGCGGAAAACAGGAAAAAT
ACGAAATGTTTGCGCCGTCAAGAATGGGAATTAAAAGATGGCTCAGTATCGTTTATACACCCCACAAAAACCCTAAAGGA
ACTGTTGTGGGACTTATCGTGCATGCTACCGATATTACGCAGAGTAAACTGGCAGAATTCGCCCTTCGTGAAAGCGAATC
AAAGCTATTGTCTGCCGTAGAGGTGGCCCAGCTGGGTACTTGGTCGCTGGATATTGCTACGGGTATCAGCACCGTCTCGC
AGCGCCATGCCGATATGTTTGGACTGAGCGGTACTGTGATGCCGGCCGAGGCTATCAGGACTTTGATCAGACCTTCGGAT
TATAAACGTGTAACGGAAGCCTTTTTAGGAGCCCAGAAGCAAGGTTCTAACGGCAGTTACGAGGCAGAGTATAGAATTAT
GCATGGGAAGAACGGCAGGGAAAAGGTTATTCATGCCGTTGGACGGACCCATTTTGATGAAAATGGAAATGCTTTGTTTA
TAAGCGGTACTACTCAGGATATTACCATTTACAGGGAATTGCAGCTGGCGTTGGAAAGCGAAGTAGAAGTGCGAACCAAT
GAACTTGCTGTTGTTTTAAAAGAACTTCAGGAAGCCAACAAAGAGCTTGAACAATCTAATAGAGCTCTAAAACACTCCAA
TGAAGAGCTGGCACAGTTCGCCTATGTTGCCAGTCATGACCTTCAGGAACCCCTGCGCAAAATTCAAATATTCGCTGCCA
TGCTGCAGGATGGGAATTCAGGAAGGGATCCAAAGACGATTATTGGCAAAATAACTGCTTCAGCGGCGCGTATGAGCCAG
CTGATCTCTGATCTGCTTGCCTTTTCAAGACTGATCCAGCCTGAAAAAAATCTCCAGACAGTGGATCTTAACCGGCTGAT
GGAAAGCATATGGACTGATTTTGAACTGACAGTTACCGAAAGTGGAGCCGAATTAGATTTCGATAACCTGCCTGTGCTGC
AGGCTGTGGCATTACAGATGAACCAGCTGTTTTATAATCTGGTAAGCAATTCGCTTAAATTCATTAGTCCGGACAGGACT
CCGAGAATAAAAATAAGTTCAGTGTTGCTGCCTTATGAGCAGGCCGCCTTACTGAGCAGTTCGGTACTGCTTTCTGTAAA
CTACTTCCATATATCTTTTATTGATAACGGTATTGGTTTTGAAAAAGACCACGAACAGCAGATTTTTGAAATTTTCAAGC
GCCTTCATGTTCAGACGGTTTTTCCGGGCAGCGGCATCGGTCTGGCATTGTGCAGGAGGATTGTTATGAACCATCAGGGT
TTTATGTACGCTGAATCTCAAATTGGACAGGGAAGCACTTTTCATATTTTCCTTCCTGACCTACCTGCCGGAGAAATCCA
GTACTAG

Upstream 100 bases:

>100_bases
CTTGATTCATGGTGTTTTAAGATGTAATTTGCTAGTGCAGATATTTTGAAATATTGCGGGTATGCCAAAATTGCACTACT
TTTAGAGCTGAACCAAATCT

Downstream 100 bases:

>100_bases
TTTTTATCTTACCTTTTGTAAAGACTGTAAATTTTCTCACTTGTAAAAAAGTTGTTTTTGGTCACAACGTGACTCTGCCA
GTCTATTGAAATTACATATT

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 828; Mature: 827

Protein sequence:

>828_residues
MTVNTEDQLPEYSFLKKGGEAGSILLQKDWSITALGTPNNWTESLRTAAGIMFSSRVPMFLVWGKEKTLLYNDPFIIFLR
ENNKHPYALGKTLTDALPQDWLVVCDAVQGIIEKGILKSESNITATVMRNGLQQKVYLTAGYSVITNKNDTIEGVFVTCL
ENSAVIPDMIGSSSVRSQLNSLLMQSNAGIAQANIQGRVVEVNDRYCQMLGYSREEILLMNLGELTHPDDLQRNMLLLQD
CIENGKDFLITKRYICRDGSVIWVNNSISVVMDQLGEKYITAIAIDITDQKEKEEKLLASEAHLQLLRDTVPAMIFYLDQ
EQRYVTYNTVFKEWFSIEGDQAVGKTVREFLGEAAYAKTLPHLKIAYGGKQEKYEMFAPSRMGIKRWLSIVYTPHKNPKG
TVVGLIVHATDITQSKLAEFALRESESKLLSAVEVAQLGTWSLDIATGISTVSQRHADMFGLSGTVMPAEAIRTLIRPSD
YKRVTEAFLGAQKQGSNGSYEAEYRIMHGKNGREKVIHAVGRTHFDENGNALFISGTTQDITIYRELQLALESEVEVRTN
ELAVVLKELQEANKELEQSNRALKHSNEELAQFAYVASHDLQEPLRKIQIFAAMLQDGNSGRDPKTIIGKITASAARMSQ
LISDLLAFSRLIQPEKNLQTVDLNRLMESIWTDFELTVTESGAELDFDNLPVLQAVALQMNQLFYNLVSNSLKFISPDRT
PRIKISSVLLPYEQAALLSSSVLLSVNYFHISFIDNGIGFEKDHEQQIFEIFKRLHVQTVFPGSGIGLALCRRIVMNHQG
FMYAESQIGQGSTFHIFLPDLPAGEIQY

Sequences:

>Translated_828_residues
MTVNTEDQLPEYSFLKKGGEAGSILLQKDWSITALGTPNNWTESLRTAAGIMFSSRVPMFLVWGKEKTLLYNDPFIIFLR
ENNKHPYALGKTLTDALPQDWLVVCDAVQGIIEKGILKSESNITATVMRNGLQQKVYLTAGYSVITNKNDTIEGVFVTCL
ENSAVIPDMIGSSSVRSQLNSLLMQSNAGIAQANIQGRVVEVNDRYCQMLGYSREEILLMNLGELTHPDDLQRNMLLLQD
CIENGKDFLITKRYICRDGSVIWVNNSISVVMDQLGEKYITAIAIDITDQKEKEEKLLASEAHLQLLRDTVPAMIFYLDQ
EQRYVTYNTVFKEWFSIEGDQAVGKTVREFLGEAAYAKTLPHLKIAYGGKQEKYEMFAPSRMGIKRWLSIVYTPHKNPKG
TVVGLIVHATDITQSKLAEFALRESESKLLSAVEVAQLGTWSLDIATGISTVSQRHADMFGLSGTVMPAEAIRTLIRPSD
YKRVTEAFLGAQKQGSNGSYEAEYRIMHGKNGREKVIHAVGRTHFDENGNALFISGTTQDITIYRELQLALESEVEVRTN
ELAVVLKELQEANKELEQSNRALKHSNEELAQFAYVASHDLQEPLRKIQIFAAMLQDGNSGRDPKTIIGKITASAARMSQ
LISDLLAFSRLIQPEKNLQTVDLNRLMESIWTDFELTVTESGAELDFDNLPVLQAVALQMNQLFYNLVSNSLKFISPDRT
PRIKISSVLLPYEQAALLSSSVLLSVNYFHISFIDNGIGFEKDHEQQIFEIFKRLHVQTVFPGSGIGLALCRRIVMNHQG
FMYAESQIGQGSTFHIFLPDLPAGEIQY
>Mature_827_residues
TVNTEDQLPEYSFLKKGGEAGSILLQKDWSITALGTPNNWTESLRTAAGIMFSSRVPMFLVWGKEKTLLYNDPFIIFLRE
NNKHPYALGKTLTDALPQDWLVVCDAVQGIIEKGILKSESNITATVMRNGLQQKVYLTAGYSVITNKNDTIEGVFVTCLE
NSAVIPDMIGSSSVRSQLNSLLMQSNAGIAQANIQGRVVEVNDRYCQMLGYSREEILLMNLGELTHPDDLQRNMLLLQDC
IENGKDFLITKRYICRDGSVIWVNNSISVVMDQLGEKYITAIAIDITDQKEKEEKLLASEAHLQLLRDTVPAMIFYLDQE
QRYVTYNTVFKEWFSIEGDQAVGKTVREFLGEAAYAKTLPHLKIAYGGKQEKYEMFAPSRMGIKRWLSIVYTPHKNPKGT
VVGLIVHATDITQSKLAEFALRESESKLLSAVEVAQLGTWSLDIATGISTVSQRHADMFGLSGTVMPAEAIRTLIRPSDY
KRVTEAFLGAQKQGSNGSYEAEYRIMHGKNGREKVIHAVGRTHFDENGNALFISGTTQDITIYRELQLALESEVEVRTNE
LAVVLKELQEANKELEQSNRALKHSNEELAQFAYVASHDLQEPLRKIQIFAAMLQDGNSGRDPKTIIGKITASAARMSQL
ISDLLAFSRLIQPEKNLQTVDLNRLMESIWTDFELTVTESGAELDFDNLPVLQAVALQMNQLFYNLVSNSLKFISPDRTP
RIKISSVLLPYEQAALLSSSVLLSVNYFHISFIDNGIGFEKDHEQQIFEIFKRLHVQTVFPGSGIGLALCRRIVMNHQGF
MYAESQIGQGSTFHIFLPDLPAGEIQY

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=244, Percent_Identity=24.5901639344262, Blast_Score=73, Evalue=9e-14,
Organism=Escherichia coli, GI1790436, Length=252, Percent_Identity=26.5873015873016, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788713, Length=322, Percent_Identity=24.8447204968944, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI145693157, Length=264, Percent_Identity=22.7272727272727, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788549, Length=264, Percent_Identity=26.1363636363636, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 92819; Mature: 92688

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVNTEDQLPEYSFLKKGGEAGSILLQKDWSITALGTPNNWTESLRTAAGIMFSSRVPMF
CCCCCCCCCCCHHHHHCCCCCCEEEEEECCEEEEECCCCCHHHHHHHHHHHHEECCCCEE
LVWGKEKTLLYNDPFIIFLRENNKHPYALGKTLTDALPQDWLVVCDAVQGIIEKGILKSE
EEECCCCEEEECCCEEEEEEECCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
SNITATVMRNGLQQKVYLTAGYSVITNKNDTIEGVFVTCLENSAVIPDMIGSSSVRSQLN
CCEEHHHHHCCCCEEEEEEECEEEEECCCCCCCEEEEEEECCCCCCHHHCCCHHHHHHHH
SLLMQSNAGIAQANIQGRVVEVNDRYCQMLGYSREEILLMNLGELTHPDDLQRNMLLLQD
HHHHHCCCCEEEECCCEEEEEECHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
CIENGKDFLITKRYICRDGSVIWVNNSISVVMDQLGEKYITAIAIDITDQKEKEEKLLAS
HHHCCCCEEEEEHEEECCCCEEEECCCHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHH
EAHLQLLRDTVPAMIFYLDQEQRYVTYNTVFKEWFSIEGDQAVGKTVREFLGEAAYAKTL
HHHHHHHHHHHCEEEEEECCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHCC
PHLKIAYGGKQEKYEMFAPSRMGIKRWLSIVYTPHKNPKGTVVGLIVHATDITQSKLAEF
CCEEEEECCCCCCEEECCCHHHHHHHHHHEEECCCCCCCCCEEEEEEEECCCCHHHHHHH
ALRESESKLLSAVEVAQLGTWSLDIATGISTVSQRHADMFGLSGTVMPAEAIRTLIRPSD
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCH
YKRVTEAFLGAQKQGSNGSYEAEYRIMHGKNGREKVIHAVGRTHFDENGNALFISGTTQD
HHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEECCCCC
ITIYRELQLALESEVEVRTNELAVVLKELQEANKELEQSNRALKHSNEELAQFAYVASHD
EEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LQEPLRKIQIFAAMLQDGNSGRDPKTIIGKITASAARMSQLISDLLAFSRLIQPEKNLQT
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VDLNRLMESIWTDFELTVTESGAELDFDNLPVLQAVALQMNQLFYNLVSNSLKFISPDRT
ECHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCC
PRIKISSVLLPYEQAALLSSSVLLSVNYFHISFIDNGIGFEKDHEQQIFEIFKRLHVQTV
CCEEEEEEECCHHHHHHHCCCEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCEEEE
FPGSGIGLALCRRIVMNHQGFMYAESQIGQGSTFHIFLPDLPAGEIQY
CCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TVNTEDQLPEYSFLKKGGEAGSILLQKDWSITALGTPNNWTESLRTAAGIMFSSRVPMF
CCCCCCCCCCHHHHHCCCCCCEEEEEECCEEEEECCCCCHHHHHHHHHHHHEECCCCEE
LVWGKEKTLLYNDPFIIFLRENNKHPYALGKTLTDALPQDWLVVCDAVQGIIEKGILKSE
EEECCCCEEEECCCEEEEEEECCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
SNITATVMRNGLQQKVYLTAGYSVITNKNDTIEGVFVTCLENSAVIPDMIGSSSVRSQLN
CCEEHHHHHCCCCEEEEEEECEEEEECCCCCCCEEEEEEECCCCCCHHHCCCHHHHHHHH
SLLMQSNAGIAQANIQGRVVEVNDRYCQMLGYSREEILLMNLGELTHPDDLQRNMLLLQD
HHHHHCCCCEEEECCCEEEEEECHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
CIENGKDFLITKRYICRDGSVIWVNNSISVVMDQLGEKYITAIAIDITDQKEKEEKLLAS
HHHCCCCEEEEEHEEECCCCEEEECCCHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHH
EAHLQLLRDTVPAMIFYLDQEQRYVTYNTVFKEWFSIEGDQAVGKTVREFLGEAAYAKTL
HHHHHHHHHHHCEEEEEECCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHCC
PHLKIAYGGKQEKYEMFAPSRMGIKRWLSIVYTPHKNPKGTVVGLIVHATDITQSKLAEF
CCEEEEECCCCCCEEECCCHHHHHHHHHHEEECCCCCCCCCEEEEEEEECCCCHHHHHHH
ALRESESKLLSAVEVAQLGTWSLDIATGISTVSQRHADMFGLSGTVMPAEAIRTLIRPSD
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCH
YKRVTEAFLGAQKQGSNGSYEAEYRIMHGKNGREKVIHAVGRTHFDENGNALFISGTTQD
HHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEECCCCC
ITIYRELQLALESEVEVRTNELAVVLKELQEANKELEQSNRALKHSNEELAQFAYVASHD
EEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LQEPLRKIQIFAAMLQDGNSGRDPKTIIGKITASAARMSQLISDLLAFSRLIQPEKNLQT
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VDLNRLMESIWTDFELTVTESGAELDFDNLPVLQAVALQMNQLFYNLVSNSLKFISPDRT
ECHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCC
PRIKISSVLLPYEQAALLSSSVLLSVNYFHISFIDNGIGFEKDHEQQIFEIFKRLHVQTV
CCEEEEEEECCHHHHHHHCCCEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCEEEE
FPGSGIGLALCRRIVMNHQGFMYAESQIGQGSTFHIFLPDLPAGEIQY
CCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]