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The map label for this gene is corA [H]

Identifier: 146301525

GI number: 146301525

Start: 4487574

End: 4488476

Strand: Direct

Name: corA [H]

Synonym: Fjoh_3786

Alternate gene names: 146301525

Gene position: 4487574-4488476 (Clockwise)

Preceding gene: 146301524

Following gene: 146301527

Centisome position: 73.6

GC content: 39.42

Gene sequence:

>903_bases
ATGGCACTAAGCAGCTGTCAGATAAAAGGTACTGAGATCACCTGGATTGATATATACAATCCTACACAGCAAGACATTGA
ATCATTCAGCAGTAAATACAGCCTGAATTCGTATGCCCTGCTCGACTCGCTCGATCCAGATCATCTTCCAAAATATGAAG
AGCATAATGATACTCATTTTTTTATTATCAGGCTCCTGCACGACGAAAAACAGAAACTTCCCACCATACAAAGCCTGAGC
AGCAAAATTGCCGTGTTTTTTACTGATAAGTTTATTATTACCATACACCGCTGTGCACAGCCTTTGATTAAGAATATCAG
GGAAAGCCTGGTTAGTACAGGAAGAATAAAATCTGCTTCAGGAATTGCCATACATATTGTGGGTGATGCCCTTCGTTCAT
TTGAAGAACCTGCCATGAAACTATCTGCCGATATTGATTCTTATGAATCCACCCTGTTTTTAAAGAAAAATATACCCGAT
GATATGATCGAAGACATTTATTATCTGAAAAACCGTGCAGGGCTCTACAAAAAATTGCTCCTGCTGAGCAACGAAGTGGT
AAACTCGATCAAAGCGGAGGGAGAAGAACGTCCTGCGCAGCGTGATGTACGTGACCTGCATACCAAGCTGGTCCTGCTCT
ATGATCAGGTACAGGAAGATGCCAACAACCTGCTCAATATTTATCTTTCCCTCTCTGCCCGTAAAACTAATGATGTTATG
AAAATCCTGACGGTTTTCTCGGTCTTTTTTATGCCGCTTACTTTTATAGTGGGAATATATGGGATGAATTTCAAATTTAT
GCCTGAATTAGAATCGCCTTTTGGATACCCTCTCACCATTATATCAATGTTTGTTATATCTATTTTGATTTTTTTCTGGT
TTAAAAGAAAGAAATGGCTTTGA

Upstream 100 bases:

>100_bases
AAAAAAGAAAAATTTCTACTTATAAAATCATGATGAAAAATATTGTAGAATTCCGTCTTATACGTCTTATTGCCAATTCA
CCATACAAACAAAAAAGATT

Downstream 100 bases:

>100_bases
TTACAAAATTGAATCGAGTATCGCAATAAGTTCTGAATAACTGTTAGGCTTCTTAAAGTACTTTATGATTGCATTTTGTT
CAAGCTTCAGTTTCATGAAT

Product: Mg2+ transporter protein, CorA family protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MALSSCQIKGTEITWIDIYNPTQQDIESFSSKYSLNSYALLDSLDPDHLPKYEEHNDTHFFIIRLLHDEKQKLPTIQSLS
SKIAVFFTDKFIITIHRCAQPLIKNIRESLVSTGRIKSASGIAIHIVGDALRSFEEPAMKLSADIDSYESTLFLKKNIPD
DMIEDIYYLKNRAGLYKKLLLLSNEVVNSIKAEGEERPAQRDVRDLHTKLVLLYDQVQEDANNLLNIYLSLSARKTNDVM
KILTVFSVFFMPLTFIVGIYGMNFKFMPELESPFGYPLTIISMFVISILIFFWFKRKKWL

Sequences:

>Translated_300_residues
MALSSCQIKGTEITWIDIYNPTQQDIESFSSKYSLNSYALLDSLDPDHLPKYEEHNDTHFFIIRLLHDEKQKLPTIQSLS
SKIAVFFTDKFIITIHRCAQPLIKNIRESLVSTGRIKSASGIAIHIVGDALRSFEEPAMKLSADIDSYESTLFLKKNIPD
DMIEDIYYLKNRAGLYKKLLLLSNEVVNSIKAEGEERPAQRDVRDLHTKLVLLYDQVQEDANNLLNIYLSLSARKTNDVM
KILTVFSVFFMPLTFIVGIYGMNFKFMPELESPFGYPLTIISMFVISILIFFWFKRKKWL
>Mature_299_residues
ALSSCQIKGTEITWIDIYNPTQQDIESFSSKYSLNSYALLDSLDPDHLPKYEEHNDTHFFIIRLLHDEKQKLPTIQSLSS
KIAVFFTDKFIITIHRCAQPLIKNIRESLVSTGRIKSASGIAIHIVGDALRSFEEPAMKLSADIDSYESTLFLKKNIPDD
MIEDIYYLKNRAGLYKKLLLLSNEVVNSIKAEGEERPAQRDVRDLHTKLVLLYDQVQEDANNLLNIYLSLSARKTNDVMK
ILTVFSVFFMPLTFIVGIYGMNFKFMPELESPFGYPLTIISMFVISILIFFWFKRKKWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=107, Percent_Identity=36.4485981308411, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 34656; Mature: 34524

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSSCQIKGTEITWIDIYNPTQQDIESFSSKYSLNSYALLDSLDPDHLPKYEEHNDTHF
CCCCCCEECCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEE
FIIRLLHDEKQKLPTIQSLSSKIAVFFTDKFIITIHRCAQPLIKNIRESLVSTGRIKSAS
EEEEEEHHHHHHCCHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GIAIHIVGDALRSFEEPAMKLSADIDSYESTLFLKKNIPDDMIEDIYYLKNRAGLYKKLL
CEEEEEEHHHHHHHHHHHHHHHCCCCCHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
LLSNEVVNSIKAEGEERPAQRDVRDLHTKLVLLYDQVQEDANNLLNIYLSLSARKTNDVM
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHH
KILTVFSVFFMPLTFIVGIYGMNFKFMPELESPFGYPLTIISMFVISILIFFWFKRKKWL
HHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALSSCQIKGTEITWIDIYNPTQQDIESFSSKYSLNSYALLDSLDPDHLPKYEEHNDTHF
CCCCCEECCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEE
FIIRLLHDEKQKLPTIQSLSSKIAVFFTDKFIITIHRCAQPLIKNIRESLVSTGRIKSAS
EEEEEEHHHHHHCCHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GIAIHIVGDALRSFEEPAMKLSADIDSYESTLFLKKNIPDDMIEDIYYLKNRAGLYKKLL
CEEEEEEHHHHHHHHHHHHHHHCCCCCHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
LLSNEVVNSIKAEGEERPAQRDVRDLHTKLVLLYDQVQEDANNLLNIYLSLSARKTNDVM
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHH
KILTVFSVFFMPLTFIVGIYGMNFKFMPELESPFGYPLTIISMFVISILIFFWFKRKKWL
HHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]