Click here to switch to the map view.

The map label for this gene is uvrD [C]

Identifier: 146301398

GI number: 146301398

Start: 4348817

End: 4350730

Strand: Direct

Name: uvrD [C]

Synonym: Fjoh_3656

Alternate gene names: 146301398

Gene position: 4348817-4350730 (Clockwise)

Preceding gene: 146301397

Following gene: 146301399

Centisome position: 71.33

GC content: 33.59

Gene sequence:

>1914_bases
ATGAGCGGAAGAATAAATAAACCAGATACTCCTGCTGATAAGAAATTACGTAACTGTTTAAAGACGAAGACGAGCTTTGT
AATGATTGCAGGCGCGGGATCAGGTAAAACCACTTCTCTTATAAAGTCGCTTAAATACATAGAAGAAACGGAAGGTATAA
ATTTACGGCAAGAAGGGAAGAAAATTGCTTGCATAACTTATACCACTGCTGCTGAAAAAGAGATATTGGACGATGTCGGA
CATGACAGCTTTTTTCACGTATCAACAATCCATAGCTTTCTATGGGAACTTATTAGGCCTTTTCAAAAGGATATTAAAAA
GTGGGTTTCATCGAAGATAGATTCTAAGCTTGAAGAATTACAAGAAGCTAGAGCAAAATTTAGTAATAGGACATGGCAAA
GTACACGGGACAACAATAAATTAGAAACAGCTAAATATCTACATATGAAAGAGAACTTTCATACTGTTAGCGAATTTCAA
TATGAAACAGGAAGCAAATATTTAGATGGTATTTTAGGTCATAGTGACATTATTGCAATGGCACCGCAAATGATTATTTC
TAACCCTCTTTTACAAATTATTTTGTCTAATAAATATCCATATTTTTTCATTGATGAAAGTCAGGATACTATACCCGAGT
TTGTTAAAGCAATGAAAGTTGTTCAAATGAATGTCAAAAATTTCTGTTTAGGTTTTTTTGGAGATCCTATGCAGAAAATT
TATCATACAGGTTCTGGAGCAATTGTTATTGAAACAGGGTGGCAAGAAATAAGGAAACCAGAAAATTTTAGATGCTCTAA
GAATGTATTAGATGTTATAAACAAAATAAGAGCACTAGGAGACGGATTAAAGAAGCAGACTGGGGGCAGGAAAATGTTCG
TTGATGGAGAATGGCAATTAATAAATGGGAGTGCGCAAATTTTTATATTGCAAGCGGATGAGCGACATGCTGAAAAAATA
GCTTTAGTACGCAGTTATCTTGCTGATCAGCTTAAAGATCCTCTTTGGAAATCTGACAAAAAGGAAGCAGATTTAAAAGT
ACTTGTTATTGAGCATAGAATAGCGGCCAACCGTCTAAAGTTTGCAGAATTGTATTCGGCTTTTAAAGACAGCTCGACAG
ACTCTTTGAGTATGAGTTTCAGTGAAGGGACATCTTGGGCGCTTATGCCATTCTTAAAATATATATTACCACTTATTAAT
GCTTATAGAAATGGAGAACATTTTCAAGTGGTTAATTTACTTCGACAATATTGTCCACTTTTACAAAAATCACATCTACA
ATTACCAGAAAGTGAACCAAGTAAAATACTTAATGAATTAAAAGTTCATCTCGAAATCATTAATAAATTATTAAAAATAG
AAAGTCCTGCTACGGTCGAAAATCTTTTTTCTTATTTGGAATCTAATAATTTAATATCTTTTGATGATAGAATTAGAACA
AGATTGAATAAAGCTTCTAAAGGTTCTCTCGAAGATGAAGACATAAGTGTTACGGATCAAGTTATTGCTAATTTTTTTAA
ATGTCCAGTTTTCCAAGTATGGGGATATGAGAGATATTTAAATGAAGAGTCACCATATTCGACTCAACACAGTATAAAAG
GTGCTGAATTTAATAGAGTAATGGTGGTGTTAGATGATGAAGAGGGAAGACGATCAACTTCGTACTCTTATGAAAGACTT
CTAGGCATAAAGGAGCTTTCTGATACAGATGTCACAAATGCTGGTAATGGTAGAGAAACTTCACAAGATAGAACTCGTAG
ATTGTTTTATGTTTGTTGCTCTAGGGCTTTAACAGATTTAGCTGTAGTATTATTTACCAACGATCCCAGATCTGCGAAAA
AAGCGGTCACTGAAACAGGGATTTTTAAAAAAAACTCCATTAAGATAGAATTAGATATCTCCAATGAAAAATAA

Upstream 100 bases:

>100_bases
AAAAACAGTTATCCGAAGAGCAACAGATTATTAAGAAGACAATAACAGTGCAAAAAAAAGATCCTAAGCCAAAAAAAAAT
AATAAAAAACAAGATCAAAT

Downstream 100 bases:

>100_bases
TGTTTAATTAATAAAATGTTTCATGATAAAACGTATTTAATACCTGTTAATTTCTATCTGAATAATTAATATTTTTGGTA
TTATTGAAAATATTATATTC

Product: superfamily I DNA/RNA helicase-like protein

Products: NA

Alternate protein names: UvrD/REP Helicase; DNA Helicase; Pathogenesis-Related Protein; ATP-Dependent DNA Helicase; Superfamily I DNA And RNA Helicase-Like Protein; ATP-Dependent DNA Helicase UvrD/REP Family; Superfamily I DNA/RNA Helicase-Like Protein; ATP-Dependent DNA Helicase UvrD; UvrD/REP Helicase Family Protein; ATP-Dependent DNA Helicase Pcra; Superfamily I DNA/RNA Helicase

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MSGRINKPDTPADKKLRNCLKTKTSFVMIAGAGSGKTTSLIKSLKYIEETEGINLRQEGKKIACITYTTAAEKEILDDVG
HDSFFHVSTIHSFLWELIRPFQKDIKKWVSSKIDSKLEELQEARAKFSNRTWQSTRDNNKLETAKYLHMKENFHTVSEFQ
YETGSKYLDGILGHSDIIAMAPQMIISNPLLQIILSNKYPYFFIDESQDTIPEFVKAMKVVQMNVKNFCLGFFGDPMQKI
YHTGSGAIVIETGWQEIRKPENFRCSKNVLDVINKIRALGDGLKKQTGGRKMFVDGEWQLINGSAQIFILQADERHAEKI
ALVRSYLADQLKDPLWKSDKKEADLKVLVIEHRIAANRLKFAELYSAFKDSSTDSLSMSFSEGTSWALMPFLKYILPLIN
AYRNGEHFQVVNLLRQYCPLLQKSHLQLPESEPSKILNELKVHLEIINKLLKIESPATVENLFSYLESNNLISFDDRIRT
RLNKASKGSLEDEDISVTDQVIANFFKCPVFQVWGYERYLNEESPYSTQHSIKGAEFNRVMVVLDDEEGRRSTSYSYERL
LGIKELSDTDVTNAGNGRETSQDRTRRLFYVCCSRALTDLAVVLFTNDPRSAKKAVTETGIFKKNSIKIELDISNEK

Sequences:

>Translated_637_residues
MSGRINKPDTPADKKLRNCLKTKTSFVMIAGAGSGKTTSLIKSLKYIEETEGINLRQEGKKIACITYTTAAEKEILDDVG
HDSFFHVSTIHSFLWELIRPFQKDIKKWVSSKIDSKLEELQEARAKFSNRTWQSTRDNNKLETAKYLHMKENFHTVSEFQ
YETGSKYLDGILGHSDIIAMAPQMIISNPLLQIILSNKYPYFFIDESQDTIPEFVKAMKVVQMNVKNFCLGFFGDPMQKI
YHTGSGAIVIETGWQEIRKPENFRCSKNVLDVINKIRALGDGLKKQTGGRKMFVDGEWQLINGSAQIFILQADERHAEKI
ALVRSYLADQLKDPLWKSDKKEADLKVLVIEHRIAANRLKFAELYSAFKDSSTDSLSMSFSEGTSWALMPFLKYILPLIN
AYRNGEHFQVVNLLRQYCPLLQKSHLQLPESEPSKILNELKVHLEIINKLLKIESPATVENLFSYLESNNLISFDDRIRT
RLNKASKGSLEDEDISVTDQVIANFFKCPVFQVWGYERYLNEESPYSTQHSIKGAEFNRVMVVLDDEEGRRSTSYSYERL
LGIKELSDTDVTNAGNGRETSQDRTRRLFYVCCSRALTDLAVVLFTNDPRSAKKAVTETGIFKKNSIKIELDISNEK
>Mature_636_residues
SGRINKPDTPADKKLRNCLKTKTSFVMIAGAGSGKTTSLIKSLKYIEETEGINLRQEGKKIACITYTTAAEKEILDDVGH
DSFFHVSTIHSFLWELIRPFQKDIKKWVSSKIDSKLEELQEARAKFSNRTWQSTRDNNKLETAKYLHMKENFHTVSEFQY
ETGSKYLDGILGHSDIIAMAPQMIISNPLLQIILSNKYPYFFIDESQDTIPEFVKAMKVVQMNVKNFCLGFFGDPMQKIY
HTGSGAIVIETGWQEIRKPENFRCSKNVLDVINKIRALGDGLKKQTGGRKMFVDGEWQLINGSAQIFILQADERHAEKIA
LVRSYLADQLKDPLWKSDKKEADLKVLVIEHRIAANRLKFAELYSAFKDSSTDSLSMSFSEGTSWALMPFLKYILPLINA
YRNGEHFQVVNLLRQYCPLLQKSHLQLPESEPSKILNELKVHLEIINKLLKIESPATVENLFSYLESNNLISFDDRIRTR
LNKASKGSLEDEDISVTDQVIANFFKCPVFQVWGYERYLNEESPYSTQHSIKGAEFNRVMVVLDDEEGRRSTSYSYERLL
GIKELSDTDVTNAGNGRETSQDRTRRLFYVCCSRALTDLAVVLFTNDPRSAKKAVTETGIFKKNSIKIELDISNEK

Specific function: Has Both Atpase And Helicase Activities. Unwinds DNA Duplexes With 3' To 5' Polarity With Respect To The Bound Strand And Initiates Unwinding Most Effectively When A Single-Stranded Region Is Present. Involved In The Post-Incision Events Of Nucleotide Exc

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 3000 [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 72820; Mature: 72689

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRINKPDTPADKKLRNCLKTKTSFVMIAGAGSGKTTSLIKSLKYIEETEGINLRQEGK
CCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHCCC
KIACITYTTAAEKEILDDVGHDSFFHVSTIHSFLWELIRPFQKDIKKWVSSKIDSKLEEL
EEEEEEEECHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEARAKFSNRTWQSTRDNNKLETAKYLHMKENFHTVSEFQYETGSKYLDGILGHSDIIAM
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHCCCCHHHHH
APQMIISNPLLQIILSNKYPYFFIDESQDTIPEFVKAMKVVQMNVKNFCLGFFGDPMQKI
HHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
YHTGSGAIVIETGWQEIRKPENFRCSKNVLDVINKIRALGDGLKKQTGGRKMFVDGEWQL
HHCCCCEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCEEEECCCEEE
INGSAQIFILQADERHAEKIALVRSYLADQLKDPLWKSDKKEADLKVLVIEHRIAANRLK
ECCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHHHHHHH
FAELYSAFKDSSTDSLSMSFSEGTSWALMPFLKYILPLINAYRNGEHFQVVNLLRQYCPL
HHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LQKSHLQLPESEPSKILNELKVHLEIINKLLKIESPATVENLFSYLESNNLISFDDRIRT
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEECHHHHHHH
RLNKASKGSLEDEDISVTDQVIANFFKCPVFQVWGYERYLNEESPYSTQHSIKGAEFNRV
HHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCHHHHCCCCCCCCCHHCCCCCCCCEE
MVVLDDEEGRRSTSYSYERLLGIKELSDTDVTNAGNGRETSQDRTRRLFYVCCSRALTDL
EEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHE
AVVLFTNDPRSAKKAVTETGIFKKNSIKIELDISNEK
EEEEEECCCHHHHHHHHHHCCEECCCEEEEEEECCCC
>Mature Secondary Structure 
SGRINKPDTPADKKLRNCLKTKTSFVMIAGAGSGKTTSLIKSLKYIEETEGINLRQEGK
CCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHCCC
KIACITYTTAAEKEILDDVGHDSFFHVSTIHSFLWELIRPFQKDIKKWVSSKIDSKLEEL
EEEEEEEECHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEARAKFSNRTWQSTRDNNKLETAKYLHMKENFHTVSEFQYETGSKYLDGILGHSDIIAM
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHCCCCHHHHH
APQMIISNPLLQIILSNKYPYFFIDESQDTIPEFVKAMKVVQMNVKNFCLGFFGDPMQKI
HHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
YHTGSGAIVIETGWQEIRKPENFRCSKNVLDVINKIRALGDGLKKQTGGRKMFVDGEWQL
HHCCCCEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCCEEEECCCEEE
INGSAQIFILQADERHAEKIALVRSYLADQLKDPLWKSDKKEADLKVLVIEHRIAANRLK
ECCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEHHHHHHHHH
FAELYSAFKDSSTDSLSMSFSEGTSWALMPFLKYILPLINAYRNGEHFQVVNLLRQYCPL
HHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LQKSHLQLPESEPSKILNELKVHLEIINKLLKIESPATVENLFSYLESNNLISFDDRIRT
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEECHHHHHHH
RLNKASKGSLEDEDISVTDQVIANFFKCPVFQVWGYERYLNEESPYSTQHSIKGAEFNRV
HHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCHHHHCCCCCCCCCHHCCCCCCCCEE
MVVLDDEEGRRSTSYSYERLLGIKELSDTDVTNAGNGRETSQDRTRRLFYVCCSRALTDL
EEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHE
AVVLFTNDPRSAKKAVTETGIFKKNSIKIELDISNEK
EEEEEECCCHHHHHHHHHHCCEECCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA