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The map label for this gene is mdtA [H]

Identifier: 146300688

GI number: 146300688

Start: 3482429

End: 3483487

Strand: Direct

Name: mdtA [H]

Synonym: Fjoh_2939

Alternate gene names: 146300688

Gene position: 3482429-3483487 (Clockwise)

Preceding gene: 146300684

Following gene: 146300689

Centisome position: 57.12

GC content: 33.99

Gene sequence:

>1059_bases
ATGAAATTAAAACATCTAATCTACGCCTTGATAATCATCGTTTTAGGAGGATTTATTACGTATAGAATAATATCCAACAA
AGGAAAGAACGACGAATCAAAAAAATTTGGCGACAAAGACAAACCAACGACAGTAACAGGATTAGTAATTCAAACTACTA
CTTTTGATAATAATTTGTCATTATCTGGTTCTATCGAAGCCAATGAACAAATTGAAATTCACAGCGAAGTTTCTGGAATT
GTAGAAGGTATTTATTTTAATGAAGGAACTTATGTGAATAAAGGTCAGGTACTTTTTAAAGTAAATGATATCGAATTAAA
AGCGCAGTTAAGACAAGCTGTAACTAAAGAAGGCTTAGCTGCAGAAAATGAAAGAAGAGCTAAACTTTTACTTCAAAAAG
AAGCCATCAGCCAGGAAGAAGCCGATGTTGCTAGAGCAGACCATGCTTCTGCGCAGGCACAAAGCCAATTAATAAGAGCA
CAAATATCTAAAACATCTGTAAAAGCACCATTTTCAGGAAAAATTGGTCTTCGTTCTATTTCACCTGGAACTTATATTAC
ACCAACTGTTTTGGTAGCAAAATTAGTAAACACAGGAAAATTAAAAATTACATTCTCTATTCCTGAAAAATATGCTTCGC
AGGTACAATCAGGATCTACTATAGATTTTACGGTTTCGGGTTCAAATAAAACCTATACAGCAAAAATATATGCCATAGAA
CCAGAGGTAGCTGTTGCAACCCGTACACTGCAGATTCGTGCTATTGCCGACAATACCGACGGAAAACTTTTCCCTGGAAC
TTTTGCCGACATCAAATTACCTTTAAACATTATTAAAGATGCTATAGTTGTTCCTTCTCAAGCTATTATTCCAATACAAG
ACGGTAAAAAAGTTTTTATTGCTGATAATGGCAAAGCAAAGGAAGTTATGGTTGATGCTACAACAAGAACCGATTCTTCA
ATTCTAATTTTATCAGGATTAAAAGCTGGAGATACTTTAATCACAAGCGGTGTTATGTCATTAAAAAACGAAGCACCAAT
TAAAGTTAAAGTAAAATAG

Upstream 100 bases:

>100_bases
AAATGTTAAATAAAAGCTAACATCTTTCGGTTTCAACGCAAAAAGTTAAATTTGCCAGTTGCAAAAACATACACCAAAAC
ACACATTCACCTAAATTTTT

Downstream 100 bases:

>100_bases
TCATAAAGACTTGAATATAGATTTAAAGATAGCAGTAAGATTTAGCAATAAATCTGAAATCTATAACCGACAATCTAAAA
TCTAAAATTACACATGAGTT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MKLKHLIYALIIIVLGGFITYRIISNKGKNDESKKFGDKDKPTTVTGLVIQTTTFDNNLSLSGSIEANEQIEIHSEVSGI
VEGIYFNEGTYVNKGQVLFKVNDIELKAQLRQAVTKEGLAAENERRAKLLLQKEAISQEEADVARADHASAQAQSQLIRA
QISKTSVKAPFSGKIGLRSISPGTYITPTVLVAKLVNTGKLKITFSIPEKYASQVQSGSTIDFTVSGSNKTYTAKIYAIE
PEVAVATRTLQIRAIADNTDGKLFPGTFADIKLPLNIIKDAIVVPSQAIIPIQDGKKVFIADNGKAKEVMVDATTRTDSS
ILILSGLKAGDTLITSGVMSLKNEAPIKVKVK

Sequences:

>Translated_352_residues
MKLKHLIYALIIIVLGGFITYRIISNKGKNDESKKFGDKDKPTTVTGLVIQTTTFDNNLSLSGSIEANEQIEIHSEVSGI
VEGIYFNEGTYVNKGQVLFKVNDIELKAQLRQAVTKEGLAAENERRAKLLLQKEAISQEEADVARADHASAQAQSQLIRA
QISKTSVKAPFSGKIGLRSISPGTYITPTVLVAKLVNTGKLKITFSIPEKYASQVQSGSTIDFTVSGSNKTYTAKIYAIE
PEVAVATRTLQIRAIADNTDGKLFPGTFADIKLPLNIIKDAIVVPSQAIIPIQDGKKVFIADNGKAKEVMVDATTRTDSS
ILILSGLKAGDTLITSGVMSLKNEAPIKVKVK
>Mature_352_residues
MKLKHLIYALIIIVLGGFITYRIISNKGKNDESKKFGDKDKPTTVTGLVIQTTTFDNNLSLSGSIEANEQIEIHSEVSGI
VEGIYFNEGTYVNKGQVLFKVNDIELKAQLRQAVTKEGLAAENERRAKLLLQKEAISQEEADVARADHASAQAQSQLIRA
QISKTSVKAPFSGKIGLRSISPGTYITPTVLVAKLVNTGKLKITFSIPEKYASQVQSGSTIDFTVSGSNKTYTAKIYAIE
PEVAVATRTLQIRAIADNTDGKLFPGTFADIKLPLNIIKDAIVVPSQAIIPIQDGKKVFIADNGKAKEVMVDATTRTDSS
ILILSGLKAGDTLITSGVMSLKNEAPIKVKVK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=315, Percent_Identity=24.1269841269841, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786787, Length=337, Percent_Identity=27.5964391691395, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789665, Length=350, Percent_Identity=24.8571428571429, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87081796, Length=369, Percent_Identity=24.1192411924119, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789929, Length=313, Percent_Identity=25.2396166134185, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38020; Mature: 38020

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKHLIYALIIIVLGGFITYRIISNKGKNDESKKFGDKDKPTTVTGLVIQTTTFDNNLS
CCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHCCCCCCCCEEEEEEEEEEEECCCEE
LSGSIEANEQIEIHSEVSGIVEGIYFNEGTYVNKGQVLFKVNDIELKAQLRQAVTKEGLA
EEECCCCCCEEEEHHHHHHHHEEEEECCCEEEECCEEEEEEECCHHHHHHHHHHHHCCCC
AENERRAKLLLQKEAISQEEADVARADHASAQAQSQLIRAQISKTSVKAPFSGKIGLRSI
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCEEEEC
SPGTYITPTVLVAKLVNTGKLKITFSIPEKYASQVQSGSTIDFTVSGSNKTYTAKIYAIE
CCCCEECHHHHHHHHHCCCEEEEEEECCHHHHHHHCCCCEEEEEEECCCCEEEEEEEEEC
PEVAVATRTLQIRAIADNTDGKLFPGTFADIKLPLNIIKDAIVVPSQAIIPIQDGKKVFI
CCEEEEEEEEEEEEEEECCCCCCCCCCCEEEEECHHHHHHHHCCCCCEEEEECCCCEEEE
ADNGKAKEVMVDATTRTDSSILILSGLKAGDTLITSGVMSLKNEAPIKVKVK
ECCCCCEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MKLKHLIYALIIIVLGGFITYRIISNKGKNDESKKFGDKDKPTTVTGLVIQTTTFDNNLS
CCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHCCCCCCCCEEEEEEEEEEEECCCEE
LSGSIEANEQIEIHSEVSGIVEGIYFNEGTYVNKGQVLFKVNDIELKAQLRQAVTKEGLA
EEECCCCCCEEEEHHHHHHHHEEEEECCCEEEECCEEEEEEECCHHHHHHHHHHHHCCCC
AENERRAKLLLQKEAISQEEADVARADHASAQAQSQLIRAQISKTSVKAPFSGKIGLRSI
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCEEEEC
SPGTYITPTVLVAKLVNTGKLKITFSIPEKYASQVQSGSTIDFTVSGSNKTYTAKIYAIE
CCCCEECHHHHHHHHHCCCEEEEEEECCHHHHHHHCCCCEEEEEEECCCCEEEEEEEEEC
PEVAVATRTLQIRAIADNTDGKLFPGTFADIKLPLNIIKDAIVVPSQAIIPIQDGKKVFI
CCEEEEEEEEEEEEEEECCCCCCCCCCCEEEEECHHHHHHHHCCCCCEEEEECCCCEEEE
ADNGKAKEVMVDATTRTDSSILILSGLKAGDTLITSGVMSLKNEAPIKVKVK
ECCCCCEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA