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The map label for this gene is recG [H]

Identifier: 146300684

GI number: 146300684

Start: 3477365

End: 3479473

Strand: Direct

Name: recG [H]

Synonym: Fjoh_2935

Alternate gene names: 146300684

Gene position: 3477365-3479473 (Clockwise)

Preceding gene: 146300680

Following gene: 146300688

Centisome position: 57.04

GC content: 34.99

Gene sequence:

>2109_bases
ATGTCTAATAATCTTCTTGAAACTCCTATCGAATACTTAAAAGGTGTTGGCCCAAGCCGTGGTCAATTGCTTCGTAAGGA
ATTAGGAATTCATAAATATGGAGATTTAGTAAATTTTTATCCAAATCGATATATAGACAGAACTCGTTATTATAAAATTA
ATGAGCTTCAAAACACCGGATCTGAAGTTCAGATTATTGGAAAAATTATCAATATAAAAACAGTCGAATTTGCTAAGAAT
AAAAAACGTCTTGTGGCTTCTTTTGTTGATGATACAGGACAAATTGAACTTAACTGGTTTCAGGGTCATAAATGGATTCG
TGAAAGTTTAAAACTTAATGAACCGCTGGTTATTTTTGGGAAATGTTCATTATACGGAAGTCAGTTCAGCATGGCGCATC
CGGAAATTGAATTGTTAAGCGAACACGAAAAAAGTCTTCGTTCTGCCATGCAGCCTGTTTATCCTTCTACAGAAACCCTT
ACAAACAGAGGAATTTCTAACAGAACAATAAACAAAATGATGGAACAGTTGTTTATTGAAACCGGAGCTTTGTTTACAGA
AACTTTTCCGCCTTATTTACTTGAAGAAGTAAAACTGATCTCAAAAAGAGCCGCTTTATTTAACATACATTTTCCTAAAA
GTGCCGATGCTTTGGCGAAAGCACAATTTAGATTGAAGTTTGAAGAATTGTTTTTTATTCAGCTGCAGTTAATTACTAAA
AACCTAATTAGAAAACATAAAATTAAAGGTCATCCTTTTACAAAAGTGGGTGAACTTTTTAATGAATTTTATCAAAATCA
TCTTCCATTTGACTTAACAAATGCTCAAAAAAGGGTAATAAAAGAAATTCGTTCTGATATGGGAAGTAATGCCCAAATGA
ACCGATTACTGCAGGGAGATGTAGGTTCTGGAAAAACAATTGTAGGTTTTATGAGCATGCTTTTGGCTATAGATAATGGT
TTTCAGGCTTGTTTGATGGCGCCGACAGAAATTTTAGCAAATCAGCATTTTATTGGTTTATCTGAGTTTGCTAATACTTT
AAACATTAGTATAAAAATCCTAACCGGTTCAACCAAAACTTCTGAAAGAAGAATTATTCATGAAGATCTCGAAAATGGAA
GTCTTCAGATTTTAATAGGAACTCACGCTTTATTAGAAGATAAAGTTAAATTTAAGAATTTAGGTCTTGCTATTATTGAT
GAGCAGCATCGTTTTGGGGTAGAACAAAGATCTAAATTGTGGAAAAAAAATGAGATTCCGCCGCACGTTTTGGTCATGAC
TGCAACGCCAATTCCGAGAACTTTAGCTATGAGTTTATACGGTGATCTGGATGTTTCTGTAATTGATGAACTGCCGCCGG
GAAGAAAACCAATTCAAACCGTTCATCGATTTGATACAAACCGTTTAAAAGTCTGGAAATTCCTGCGTGATGAAATTGCG
AAAGGCAGACAGATTTATATTGTTTATCCATTAATTCAGGAATCTGAAAAAATGGATTACAAAGATTTGATGGATGGTTA
CGAAAGTATTTCAAGAGATTTTCCGCTGCCGCAATATTCAATTTCAATTGTTCATGGAAAGATGAAACCTGCGGATAAAG
ATGCCGAAATGAAACGTTTCTCAGAAGGAAAAACAAATATTATGGTGGCTACAACCGTAATTGAAGTTGGTGTAAATGTG
CCTAATGCCAGTGTTATGATTATTGAAAGTGCCGAACGTTTTGGTCTTTCGCAGCTGCATCAGCTTAGAGGACGTGTTGG
ACGTGGTGCTGAACAGAGTTATTGTATTTTAATGACTGGACATAAATTAAGCTCTGACAGTAAAACCCGAATGGAAACTA
TGGTGCAGACCAATGATGGTTTTGAAATTGCCGAAGTCGATCTCAAACTTCGCGGTCCCGGAGATTTAATGGGAACGCAG
CAAAGCGGTGTTTTAAACCTGCAGATTGCTGATATTGTAAAAGACAGAGAGATTTTGTCTTTCGCCAGAAATTATGCCCT
GAAAATCTTAAAAGAAGATCCACCGTTACAAAAACCCGAACACGCTATTTTAAAAACTGTTTTCTTAGAATTAACGAAAA
GAAAAAATATTTGGAATTATATTTCTTAG

Upstream 100 bases:

>100_bases
TTCTAAATAAAAGAGCATAGAACAAAGAATATAGATTATTTTTATTTAAAATCAACAATCTAAAATCTATAGTCTAAAAA
TCTAAAATTCAAAATTCTTC

Downstream 100 bases:

>100_bases
TCGCTGGCGCTCTAGGAAGGAACAAAGACACAAAGGTGCAAAGTCACAAAGTTTTTTAATGAGTATCATTCCGAGGAAAG
TCGAAGGCTAAAAAACCTTT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 702; Mature: 701

Protein sequence:

>702_residues
MSNNLLETPIEYLKGVGPSRGQLLRKELGIHKYGDLVNFYPNRYIDRTRYYKINELQNTGSEVQIIGKIINIKTVEFAKN
KKRLVASFVDDTGQIELNWFQGHKWIRESLKLNEPLVIFGKCSLYGSQFSMAHPEIELLSEHEKSLRSAMQPVYPSTETL
TNRGISNRTINKMMEQLFIETGALFTETFPPYLLEEVKLISKRAALFNIHFPKSADALAKAQFRLKFEELFFIQLQLITK
NLIRKHKIKGHPFTKVGELFNEFYQNHLPFDLTNAQKRVIKEIRSDMGSNAQMNRLLQGDVGSGKTIVGFMSMLLAIDNG
FQACLMAPTEILANQHFIGLSEFANTLNISIKILTGSTKTSERRIIHEDLENGSLQILIGTHALLEDKVKFKNLGLAIID
EQHRFGVEQRSKLWKKNEIPPHVLVMTATPIPRTLAMSLYGDLDVSVIDELPPGRKPIQTVHRFDTNRLKVWKFLRDEIA
KGRQIYIVYPLIQESEKMDYKDLMDGYESISRDFPLPQYSISIVHGKMKPADKDAEMKRFSEGKTNIMVATTVIEVGVNV
PNASVMIIESAERFGLSQLHQLRGRVGRGAEQSYCILMTGHKLSSDSKTRMETMVQTNDGFEIAEVDLKLRGPGDLMGTQ
QSGVLNLQIADIVKDREILSFARNYALKILKEDPPLQKPEHAILKTVFLELTKRKNIWNYIS

Sequences:

>Translated_702_residues
MSNNLLETPIEYLKGVGPSRGQLLRKELGIHKYGDLVNFYPNRYIDRTRYYKINELQNTGSEVQIIGKIINIKTVEFAKN
KKRLVASFVDDTGQIELNWFQGHKWIRESLKLNEPLVIFGKCSLYGSQFSMAHPEIELLSEHEKSLRSAMQPVYPSTETL
TNRGISNRTINKMMEQLFIETGALFTETFPPYLLEEVKLISKRAALFNIHFPKSADALAKAQFRLKFEELFFIQLQLITK
NLIRKHKIKGHPFTKVGELFNEFYQNHLPFDLTNAQKRVIKEIRSDMGSNAQMNRLLQGDVGSGKTIVGFMSMLLAIDNG
FQACLMAPTEILANQHFIGLSEFANTLNISIKILTGSTKTSERRIIHEDLENGSLQILIGTHALLEDKVKFKNLGLAIID
EQHRFGVEQRSKLWKKNEIPPHVLVMTATPIPRTLAMSLYGDLDVSVIDELPPGRKPIQTVHRFDTNRLKVWKFLRDEIA
KGRQIYIVYPLIQESEKMDYKDLMDGYESISRDFPLPQYSISIVHGKMKPADKDAEMKRFSEGKTNIMVATTVIEVGVNV
PNASVMIIESAERFGLSQLHQLRGRVGRGAEQSYCILMTGHKLSSDSKTRMETMVQTNDGFEIAEVDLKLRGPGDLMGTQ
QSGVLNLQIADIVKDREILSFARNYALKILKEDPPLQKPEHAILKTVFLELTKRKNIWNYIS
>Mature_701_residues
SNNLLETPIEYLKGVGPSRGQLLRKELGIHKYGDLVNFYPNRYIDRTRYYKINELQNTGSEVQIIGKIINIKTVEFAKNK
KRLVASFVDDTGQIELNWFQGHKWIRESLKLNEPLVIFGKCSLYGSQFSMAHPEIELLSEHEKSLRSAMQPVYPSTETLT
NRGISNRTINKMMEQLFIETGALFTETFPPYLLEEVKLISKRAALFNIHFPKSADALAKAQFRLKFEELFFIQLQLITKN
LIRKHKIKGHPFTKVGELFNEFYQNHLPFDLTNAQKRVIKEIRSDMGSNAQMNRLLQGDVGSGKTIVGFMSMLLAIDNGF
QACLMAPTEILANQHFIGLSEFANTLNISIKILTGSTKTSERRIIHEDLENGSLQILIGTHALLEDKVKFKNLGLAIIDE
QHRFGVEQRSKLWKKNEIPPHVLVMTATPIPRTLAMSLYGDLDVSVIDELPPGRKPIQTVHRFDTNRLKVWKFLRDEIAK
GRQIYIVYPLIQESEKMDYKDLMDGYESISRDFPLPQYSISIVHGKMKPADKDAEMKRFSEGKTNIMVATTVIEVGVNVP
NASVMIIESAERFGLSQLHQLRGRVGRGAEQSYCILMTGHKLSSDSKTRMETMVQTNDGFEIAEVDLKLRGPGDLMGTQQ
SGVLNLQIADIVKDREILSFARNYALKILKEDPPLQKPEHAILKTVFLELTKRKNIWNYIS

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=691, Percent_Identity=39.2185238784371, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1787357, Length=391, Percent_Identity=37.5959079283887, Blast_Score=260, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 80088; Mature: 79957

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNLLETPIEYLKGVGPSRGQLLRKELGIHKYGDLVNFYPNRYIDRTRYYKINELQNTG
CCCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHHCCHHHHCCCHHCCCCCCEEEHHHHCCC
SEVQIIGKIINIKTVEFAKNKKRLVASFVDDTGQIELNWFQGHKWIRESLKLNEPLVIFG
CCEEEEEEHHEEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCEEEEE
KCSLYGSQFSMAHPEIELLSEHEKSLRSAMQPVYPSTETLTNRGISNRTINKMMEQLFIE
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHH
TGALFTETFPPYLLEEVKLISKRAALFNIHFPKSADALAKAQFRLKFEELFFIQLQLITK
CCCHHHCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHEEHHHHHHHHHHHHHH
NLIRKHKIKGHPFTKVGELFNEFYQNHLPFDLTNAQKRVIKEIRSDMGSNAQMNRLLQGD
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCC
VGSGKTIVGFMSMLLAIDNGFQACLMAPTEILANQHFIGLSEFANTLNISIKILTGSTKT
CCCCCHHHHHHHHHHHHCCCCHHHHCCCHHHHCCCCCEEHHHHCCEEEEEEEEEECCCCC
SERRIIHEDLENGSLQILIGTHALLEDKVKFKNLGLAIIDEQHRFGVEQRSKLWKKNEIP
CHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCEEEEECHHHCCHHHHHHHHHCCCCC
PHVLVMTATPIPRTLAMSLYGDLDVSVIDELPPGRKPIQTVHRFDTNRLKVWKFLRDEIA
CEEEEEECCCCCHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHC
KGRQIYIVYPLIQESEKMDYKDLMDGYESISRDFPLPQYSISIVHGKMKPADKDAEMKRF
CCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHH
SEGKTNIMVATTVIEVGVNVPNASVMIIESAERFGLSQLHQLRGRVGRGAEQSYCILMTG
CCCCCEEEEEEEEEEECCCCCCCEEEEEECHHHCCHHHHHHHHHHHCCCCCCCEEEEEEC
HKLSSDSKTRMETMVQTNDGFEIAEVDLKLRGPGDLMGTQQSGVLNLQIADIVKDREILS
CCCCCCHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHH
FARNYALKILKEDPPLQKPEHAILKTVFLELTKRKNIWNYIS
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SNNLLETPIEYLKGVGPSRGQLLRKELGIHKYGDLVNFYPNRYIDRTRYYKINELQNTG
CCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHHCCHHHHCCCHHCCCCCCEEEHHHHCCC
SEVQIIGKIINIKTVEFAKNKKRLVASFVDDTGQIELNWFQGHKWIRESLKLNEPLVIFG
CCEEEEEEHHEEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCEEEEE
KCSLYGSQFSMAHPEIELLSEHEKSLRSAMQPVYPSTETLTNRGISNRTINKMMEQLFIE
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHH
TGALFTETFPPYLLEEVKLISKRAALFNIHFPKSADALAKAQFRLKFEELFFIQLQLITK
CCCHHHCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHEEHHHHHHHHHHHHHH
NLIRKHKIKGHPFTKVGELFNEFYQNHLPFDLTNAQKRVIKEIRSDMGSNAQMNRLLQGD
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCC
VGSGKTIVGFMSMLLAIDNGFQACLMAPTEILANQHFIGLSEFANTLNISIKILTGSTKT
CCCCCHHHHHHHHHHHHCCCCHHHHCCCHHHHCCCCCEEHHHHCCEEEEEEEEEECCCCC
SERRIIHEDLENGSLQILIGTHALLEDKVKFKNLGLAIIDEQHRFGVEQRSKLWKKNEIP
CHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCEEEEECHHHCCHHHHHHHHHCCCCC
PHVLVMTATPIPRTLAMSLYGDLDVSVIDELPPGRKPIQTVHRFDTNRLKVWKFLRDEIA
CEEEEEECCCCCHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHC
KGRQIYIVYPLIQESEKMDYKDLMDGYESISRDFPLPQYSISIVHGKMKPADKDAEMKRF
CCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHH
SEGKTNIMVATTVIEVGVNVPNASVMIIESAERFGLSQLHQLRGRVGRGAEQSYCILMTG
CCCCCEEEEEEEEEEECCCCCCCEEEEEECHHHCCHHHHHHHHHHHCCCCCCCEEEEEEC
HKLSSDSKTRMETMVQTNDGFEIAEVDLKLRGPGDLMGTQQSGVLNLQIADIVKDREILS
CCCCCCHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHH
FARNYALKILKEDPPLQKPEHAILKTVFLELTKRKNIWNYIS
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]