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The map label for this gene is sucD [H]

Identifier: 146300647

GI number: 146300647

Start: 3440987

End: 3441859

Strand: Reverse

Name: sucD [H]

Synonym: Fjoh_2898

Alternate gene names: 146300647

Gene position: 3441859-3440987 (Counterclockwise)

Preceding gene: 146300648

Following gene: 146300646

Centisome position: 56.45

GC content: 37.8

Gene sequence:

>873_bases
ATGAGTGTTTTAGTTAATAAAGATTCCAAAATAATTGTTCAGGGATTTACAGGAAGCGAAGGAACTTTCCACGCTTCTCA
AATGATTGAGTACGGTACTAATGTTGTTGGTGGTGTTACTCCAGGAAAAGGAGGTACAAGCCATTTAGACCGCCCGGTTT
TTAATACAGTAAAAGATGCTGTTGATCAAGCTGGTGCAGATACTTCTATCATTTTTGTTCCGCCGGCTTTTGCTGCTGAT
GCAATTATGGAAGCTGCTGATGCTGGAATTAAAGTAATTATTGCTATTACAGAAGGAATTCCTGTAGCAGACATGATTAA
AGCAAATAATTATGTTAAAGAAAGAAGTTCTAGATTAATTGGACCAAACTGTCCGGGTGTTATTACTCCAGGTGAGGCTA
AAGTTGGAATTATGCCAGGTTTCGTTTTCAAAAAAGGAACTGTTGGTATCGTTTCTAAATCAGGAACTTTAACTTATGAA
GCTGCTGACCAAGTTGTAAAACAAGGTTTAGGAATTACTACAGCTATTGGTATTGGTGGAGATCCAATTATTGGAACTAC
AACTAAAGAAGCTGTTGAATTATTAATGAACGATCCAGAAACTGAAGCAATCATTATGATTGGTGAAATTGGAGGTCAAT
TAGAAGCTGATGCTGCAAAATGGGTAAAAGCTGATGGTAACCGTAAACCAGTTATTGGTTTTATTGCTGGAGAAACTGCT
CCTGCTGGTAGAACAATGGGTCACGCAGGTGCAATCGTTGGAGGTTCTGATGATACGGCTGCTGCTAAAAAACAAATTAT
GAGAGACAACGGAATTCACGTTGTTGATTCACCAGCTGAAATTGGTAAAAAAGTAAAAGAAGTATTAGGATAA

Upstream 100 bases:

>100_bases
GTCAATTTTCTTAATATTTTTTTGACAATAAAAGAGGCAAAATACATTACAAAACCTTATTTTTGCAACACAAATTTAAA
AACTACATAAAATATATATC

Downstream 100 bases:

>100_bases
TCTCTAATATCAAAATAATAAATTCCAAAAAAGTCTCAATATCCTGTTGAGACTTTTTTACATTTTAAAAACTGAGGCAT
AGATAGGAAAAACTTAGCAT

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSVLVNKDSKIIVQGFTGSEGTFHASQMIEYGTNVVGGVTPGKGGTSHLDRPVFNTVKDAVDQAGADTSIIFVPPAFAAD
AIMEAADAGIKVIIAITEGIPVADMIKANNYVKERSSRLIGPNCPGVITPGEAKVGIMPGFVFKKGTVGIVSKSGTLTYE
AADQVVKQGLGITTAIGIGGDPIIGTTTKEAVELLMNDPETEAIIMIGEIGGQLEADAAKWVKADGNRKPVIGFIAGETA
PAGRTMGHAGAIVGGSDDTAAAKKQIMRDNGIHVVDSPAEIGKKVKEVLG

Sequences:

>Translated_290_residues
MSVLVNKDSKIIVQGFTGSEGTFHASQMIEYGTNVVGGVTPGKGGTSHLDRPVFNTVKDAVDQAGADTSIIFVPPAFAAD
AIMEAADAGIKVIIAITEGIPVADMIKANNYVKERSSRLIGPNCPGVITPGEAKVGIMPGFVFKKGTVGIVSKSGTLTYE
AADQVVKQGLGITTAIGIGGDPIIGTTTKEAVELLMNDPETEAIIMIGEIGGQLEADAAKWVKADGNRKPVIGFIAGETA
PAGRTMGHAGAIVGGSDDTAAAKKQIMRDNGIHVVDSPAEIGKKVKEVLG
>Mature_289_residues
SVLVNKDSKIIVQGFTGSEGTFHASQMIEYGTNVVGGVTPGKGGTSHLDRPVFNTVKDAVDQAGADTSIIFVPPAFAADA
IMEAADAGIKVIIAITEGIPVADMIKANNYVKERSSRLIGPNCPGVITPGEAKVGIMPGFVFKKGTVGIVSKSGTLTYEA
ADQVVKQGLGITTAIGIGGDPIIGTTTKEAVELLMNDPETEAIIMIGEIGGQLEADAAKWVKADGNRKPVIGFIAGETAP
AGRTMGHAGAIVGGSDDTAAAKKQIMRDNGIHVVDSPAEIGKKVKEVLG

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=287, Percent_Identity=54.3554006968641, Blast_Score=268, Evalue=3e-72,
Organism=Homo sapiens, GI38569423, Length=250, Percent_Identity=30.4, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI38569421, Length=250, Percent_Identity=30.4, Blast_Score=99, Evalue=3e-21,
Organism=Escherichia coli, GI1786949, Length=289, Percent_Identity=56.7474048442907, Blast_Score=325, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=53.7671232876712, Blast_Score=299, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI17550194, Length=282, Percent_Identity=53.1914893617021, Blast_Score=289, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI17557344, Length=249, Percent_Identity=28.9156626506024, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17551266, Length=220, Percent_Identity=30, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324716, Length=292, Percent_Identity=48.972602739726, Blast_Score=266, Evalue=4e-72,
Organism=Drosophila melanogaster, GI21356559, Length=287, Percent_Identity=48.780487804878, Blast_Score=290, Evalue=9e-79,
Organism=Drosophila melanogaster, GI28574296, Length=285, Percent_Identity=49.1228070175439, Blast_Score=245, Evalue=2e-65,
Organism=Drosophila melanogaster, GI281363477, Length=252, Percent_Identity=28.968253968254, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281363475, Length=252, Percent_Identity=28.968253968254, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281363473, Length=252, Percent_Identity=28.968253968254, Blast_Score=98, Evalue=5e-21,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29736; Mature: 29605

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVNKDSKIIVQGFTGSEGTFHASQMIEYGTNVVGGVTPGKGGTSHLDRPVFNTVKDA
CEEEEECCCEEEEEECCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCCCCCHHHHHHHHH
VDQAGADTSIIFVPPAFAADAIMEAADAGIKVIIAITEGIPVADMIKANNYVKERSSRLI
HHHCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCC
GPNCPGVITPGEAKVGIMPGFVFKKGTVGIVSKSGTLTYEAADQVVKQGLGITTAIGIGG
CCCCCCEECCCCCEEEECCCEEECCCCEEEEECCCEEEHHHHHHHHHCCCCEEEEECCCC
DPIIGTTTKEAVELLMNDPETEAIIMIGEIGGQLEADAAKWVKADGNRKPVIGFIAGETA
CCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCEEEEEECCCC
PAGRTMGHAGAIVGGSDDTAAAKKQIMRDNGIHVVDSPAEIGKKVKEVLG
CCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHC
>Mature Secondary Structure 
SVLVNKDSKIIVQGFTGSEGTFHASQMIEYGTNVVGGVTPGKGGTSHLDRPVFNTVKDA
EEEEECCCEEEEEECCCCCCCCHHHHHHHHCCCEECCCCCCCCCCCCCCCHHHHHHHHH
VDQAGADTSIIFVPPAFAADAIMEAADAGIKVIIAITEGIPVADMIKANNYVKERSSRLI
HHHCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCC
GPNCPGVITPGEAKVGIMPGFVFKKGTVGIVSKSGTLTYEAADQVVKQGLGITTAIGIGG
CCCCCCEECCCCCEEEECCCEEECCCCEEEEECCCEEEHHHHHHHHHCCCCEEEEECCCC
DPIIGTTTKEAVELLMNDPETEAIIMIGEIGGQLEADAAKWVKADGNRKPVIGFIAGETA
CCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCEEEEEECCCC
PAGRTMGHAGAIVGGSDDTAAAKKQIMRDNGIHVVDSPAEIGKKVKEVLG
CCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]