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The map label for this gene is cbbY [H]

Identifier: 146300527

GI number: 146300527

Start: 3310072

End: 3310734

Strand: Direct

Name: cbbY [H]

Synonym: Fjoh_2777

Alternate gene names: 146300527

Gene position: 3310072-3310734 (Clockwise)

Preceding gene: 146300526

Following gene: 146300528

Centisome position: 54.29

GC content: 33.63

Gene sequence:

>663_bases
ATGATTAAAACAGTAATTTTTGATATGGACGGCGTAATTGTCGATACAGAACCCGTTCATCGTTATGCATACTACAAACA
ATTTTCAGAATTAAATATTGAGGTTCCTGAGGAAATGTACACTTCATTTACAGGATTCTCGACCCGAAATACTTTTCAAA
CCTTAAAAGGACATTTTCCGACAATTGAGCATGAGGTTGAAGATTTAATTCAAAGAAAAAGAAACCTTTTTAACGATGCT
TTTGACACAAAAGAAGATTTATATCTATTAGAAGGTGTCGAAGATTTGATAAAAGATTTATATACAAACGGAATTCAATT
GATTCTGGCTTCGTCGGCTTCAAAAGTTACAATCGAACGTGTATTTACAAGATTTAATCTGCATCAGTATTTTTCGCATA
TTGTAAGCGGAGAAGATTTTCCGCAGTCAAAACCAAATCCTGCTATTTTTATTCACGCAGCTTCATTATCAATTGCGCCA
AAAGAAGAATGTATTATAATCGAAGACAGCACAAATGGGGTAAAAGCAGCAAAAGGCGCCGGAATTTATTGTGTGGGTTA
TAACAGTAATCATTCGTATATGCAGGATCTTTCTGATGCTGATATGATTATCAATCATTTTAACGAATTAAATGCCGAAA
AAATATCACAGCTTAAAGCTTGA

Upstream 100 bases:

>100_bases
AATTTTAGTATCTTAAAAAATAAAAACTTTATAAGAGTTTAATCTCAAGCAATAAACCTTAGAATCTTAGTCCCTCAGAA
CCTTAGTACCTTTAAAAAAA

Downstream 100 bases:

>100_bases
ATTATATAAAATTTAACATTTGTTAGGTAATTGAATTCGTAATTTTGAAAAAAAACAAATAAACTCTATAATGAAAAAAA
TACTTATTGCATTAGCTGTT

Product: HAD family hydrolase

Products: Beta-D-Glucose 6- Phosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MIKTVIFDMDGVIVDTEPVHRYAYYKQFSELNIEVPEEMYTSFTGFSTRNTFQTLKGHFPTIEHEVEDLIQRKRNLFNDA
FDTKEDLYLLEGVEDLIKDLYTNGIQLILASSASKVTIERVFTRFNLHQYFSHIVSGEDFPQSKPNPAIFIHAASLSIAP
KEECIIIEDSTNGVKAAKGAGIYCVGYNSNHSYMQDLSDADMIINHFNELNAEKISQLKA

Sequences:

>Translated_220_residues
MIKTVIFDMDGVIVDTEPVHRYAYYKQFSELNIEVPEEMYTSFTGFSTRNTFQTLKGHFPTIEHEVEDLIQRKRNLFNDA
FDTKEDLYLLEGVEDLIKDLYTNGIQLILASSASKVTIERVFTRFNLHQYFSHIVSGEDFPQSKPNPAIFIHAASLSIAP
KEECIIIEDSTNGVKAAKGAGIYCVGYNSNHSYMQDLSDADMIINHFNELNAEKISQLKA
>Mature_220_residues
MIKTVIFDMDGVIVDTEPVHRYAYYKQFSELNIEVPEEMYTSFTGFSTRNTFQTLKGHFPTIEHEVEDLIQRKRNLFNDA
FDTKEDLYLLEGVEDLIKDLYTNGIQLILASSASKVTIERVFTRFNLHQYFSHIVSGEDFPQSKPNPAIFIHAASLSIAP
KEECIIIEDSTNGVKAAKGAGIYCVGYNSNHSYMQDLSDADMIINHFNELNAEKISQLKA

Specific function: Reversible Transformation Of Glucose 6-Phosphate And Beta-Glucose 1-Phosphate (By Similarity). [C]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=215, Percent_Identity=26.5116279069767, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI207113149, Length=153, Percent_Identity=30.0653594771242, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787576, Length=221, Percent_Identity=25.7918552036199, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788021, Length=191, Percent_Identity=28.7958115183246, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1789787, Length=231, Percent_Identity=26.8398268398268, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789046, Length=187, Percent_Identity=26.2032085561497, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790151, Length=187, Percent_Identity=26.7379679144385, Blast_Score=69, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116008157, Length=218, Percent_Identity=26.1467889908257, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17137324, Length=219, Percent_Identity=26.4840182648402, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 5.4.2.6 [C]

Molecular weight: Translated: 25047; Mature: 25047

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTVIFDMDGVIVDTEPVHRYAYYKQFSELNIEVPEEMYTSFTGFSTRNTFQTLKGHFP
CCEEEEEECCCEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHCCCC
TIEHEVEDLIQRKRNLFNDAFDTKEDLYLLEGVEDLIKDLYTNGIQLILASSASKVTIER
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHH
VFTRFNLHQYFSHIVSGEDFPQSKPNPAIFIHAASLSIAPKEECIIIEDSTNGVKAAKGA
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEEECCCCCCCCCCCC
GIYCVGYNSNHSYMQDLSDADMIINHFNELNAEKISQLKA
CEEEEEECCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure
MIKTVIFDMDGVIVDTEPVHRYAYYKQFSELNIEVPEEMYTSFTGFSTRNTFQTLKGHFP
CCEEEEEECCCEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHCCCC
TIEHEVEDLIQRKRNLFNDAFDTKEDLYLLEGVEDLIKDLYTNGIQLILASSASKVTIER
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHH
VFTRFNLHQYFSHIVSGEDFPQSKPNPAIFIHAASLSIAPKEECIIIEDSTNGVKAAKGA
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEEECCCCCCCCCCCC
GIYCVGYNSNHSYMQDLSDADMIINHFNELNAEKISQLKA
CEEEEEECCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Beta-D-Glucose 1-Phosphate [C]

Specific reaction: Beta-D-Glucose 1-Phosphate = Beta-D-Glucose 6- Phosphate. [C]

General reaction: Group transfer (intramolecular phosphate group isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006018 [H]