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The map label for this gene is argD [H]

Identifier: 146300346

GI number: 146300346

Start: 3085774

End: 3086967

Strand: Reverse

Name: argD [H]

Synonym: Fjoh_2591

Alternate gene names: 146300346

Gene position: 3086967-3085774 (Counterclockwise)

Preceding gene: 146300347

Following gene: 146300345

Centisome position: 50.63

GC content: 38.78

Gene sequence:

>1194_bases
ATGAACCCAGATTTTATAAAATACCAGGCACAAACTTCTCCTTATCCTTTAGGAATGGAAGTTTCACATGCTGTTGGATC
TTACATATACGATACAAACAATAAAAAATATTTAGATTTTGTTGCCGGAGTTTCGGCTTGCACGCTTGGGCATCAGCATC
CGAGAGTGAACCAGGCAATTAAAGACCAGTTAGACAAATATTCGCATGTAATGGTTTACGGAGAATATTCGCAAAGTCCG
GCTGTGCAATATTGCAAATTAATGGCCTCTCTCCTTCCGGAATCTTTAAATAAAACCTATTTAGTCAATTCGGGTACAGA
AGCGATAGAAGGTGCTTTAAAACTCGCTAAAAGAACAACAGGACGCAGTCAGCTTATTTCATGTCACAATGCTTATCATG
GAAACACAATGGGTTCTATGAGCGTAATGGGATTTGAAGAACGCAAACAAGCTTTTAGACCTTTGCTTCCGGATGTAGAT
TTTATTACTTTTAACAACGAAGCCGATCTTGAAAAAATAACAACCAGAACCGCAGCAATTCTTCTTGAAACCATTCAGGG
AGGTGCCGGATTTATTCAGCCGGAAAATAACTTTCTGCAAAAAGTCCGCAAGCGTTGTGATGAAGTTGGAGCCTTGATGA
TTGTTGATGAAATTCAGCCGGGTTTTGGAAGAACAGGAAAGCTTTTTGGTTTTCAAAACTATGATGTTATTCCAGATATT
GTGGTTATGGGAAAAGGTATGGGAGGCGGTATGCCGGTTGGAGCTTTTACAGCTTCGGCAGAAAAAATGGACCTTTTAAC
AGAAAATCCAAAATTAGGTCATATAACCACTTTTGGAGGCCATCCTGTCATTGCGTCAGCTTGCCTGGCTACTTTGCAGG
AATTAACTGAAACAAATTTAATGAACGAAGCGCTGGAAAAGGAAAAACTGTTCAGATCGCTTTTGGTACATCCTTTGATA
AAAGAAGTTAGAGGAAAAGGATTAATGCTGGCCGCAATGACCGAAACAGCAGATATAACCAATGAAGTGATTTTAAATTG
TCAAGATAAAGGTTTAATACTGTTCTGGCTTCTGTTTGAAGGATGTGCAATTCGAATAACACCGCCATTAACCATTTCCG
AAGAAGAAATAAAGGAAGGCTGTTCTATAATTTTAGAAGTTATGGACGAAATAATGAGAAAACAGCAAGCTTAA

Upstream 100 bases:

>100_bases
TTCAGTATTCAATCTCAGTTTATAAAACCTGAAACTTTAAACCTGAAACAAGATAACCCTCAGAACCTTAGTACCTTTGC
TACTTTGAACCTTTAAAAAA

Downstream 100 bases:

>100_bases
TATCAACCAAATTAATCTTTTAAAAATCAAAAGATTAAATCTAAAAACAGAATAAAAATTCTGTCCTTATTGTTAATTAA
ATTGTTCAAAACAATTAATT

Product: class III aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNPDFIKYQAQTSPYPLGMEVSHAVGSYIYDTNNKKYLDFVAGVSACTLGHQHPRVNQAIKDQLDKYSHVMVYGEYSQSP
AVQYCKLMASLLPESLNKTYLVNSGTEAIEGALKLAKRTTGRSQLISCHNAYHGNTMGSMSVMGFEERKQAFRPLLPDVD
FITFNNEADLEKITTRTAAILLETIQGGAGFIQPENNFLQKVRKRCDEVGALMIVDEIQPGFGRTGKLFGFQNYDVIPDI
VVMGKGMGGGMPVGAFTASAEKMDLLTENPKLGHITTFGGHPVIASACLATLQELTETNLMNEALEKEKLFRSLLVHPLI
KEVRGKGLMLAAMTETADITNEVILNCQDKGLILFWLLFEGCAIRITPPLTISEEEIKEGCSIILEVMDEIMRKQQA

Sequences:

>Translated_397_residues
MNPDFIKYQAQTSPYPLGMEVSHAVGSYIYDTNNKKYLDFVAGVSACTLGHQHPRVNQAIKDQLDKYSHVMVYGEYSQSP
AVQYCKLMASLLPESLNKTYLVNSGTEAIEGALKLAKRTTGRSQLISCHNAYHGNTMGSMSVMGFEERKQAFRPLLPDVD
FITFNNEADLEKITTRTAAILLETIQGGAGFIQPENNFLQKVRKRCDEVGALMIVDEIQPGFGRTGKLFGFQNYDVIPDI
VVMGKGMGGGMPVGAFTASAEKMDLLTENPKLGHITTFGGHPVIASACLATLQELTETNLMNEALEKEKLFRSLLVHPLI
KEVRGKGLMLAAMTETADITNEVILNCQDKGLILFWLLFEGCAIRITPPLTISEEEIKEGCSIILEVMDEIMRKQQA
>Mature_397_residues
MNPDFIKYQAQTSPYPLGMEVSHAVGSYIYDTNNKKYLDFVAGVSACTLGHQHPRVNQAIKDQLDKYSHVMVYGEYSQSP
AVQYCKLMASLLPESLNKTYLVNSGTEAIEGALKLAKRTTGRSQLISCHNAYHGNTMGSMSVMGFEERKQAFRPLLPDVD
FITFNNEADLEKITTRTAAILLETIQGGAGFIQPENNFLQKVRKRCDEVGALMIVDEIQPGFGRTGKLFGFQNYDVIPDI
VVMGKGMGGGMPVGAFTASAEKMDLLTENPKLGHITTFGGHPVIASACLATLQELTETNLMNEALEKEKLFRSLLVHPLI
KEVRGKGLMLAAMTETADITNEVILNCQDKGLILFWLLFEGCAIRITPPLTISEEEIKEGCSIILEVMDEIMRKQQA

Specific function: Unknown

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=402, Percent_Identity=32.5870646766169, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI13994255, Length=422, Percent_Identity=27.2511848341232, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI37574042, Length=416, Percent_Identity=28.3653846153846, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI24119277, Length=343, Percent_Identity=29.4460641399417, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI226442705, Length=416, Percent_Identity=27.1634615384615, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI226442709, Length=386, Percent_Identity=28.4974093264249, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=33.4448160535117, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI188536080, Length=432, Percent_Identity=22.4537037037037, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI38679950, Length=432, Percent_Identity=22.4537037037037, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI38679946, Length=432, Percent_Identity=22.4537037037037, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI145693181, Length=405, Percent_Identity=35.3086419753086, Blast_Score=217, Evalue=9e-58,
Organism=Escherichia coli, GI1789016, Length=428, Percent_Identity=32.9439252336449, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1788044, Length=370, Percent_Identity=32.4324324324324, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1789759, Length=371, Percent_Identity=29.3800539083558, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1787560, Length=425, Percent_Identity=28.9411764705882, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1786991, Length=399, Percent_Identity=28.3208020050125, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1786349, Length=300, Percent_Identity=32.3333333333333, Blast_Score=144, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI32564660, Length=420, Percent_Identity=29.5238095238095, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI25144271, Length=403, Percent_Identity=30.0248138957816, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=423, Percent_Identity=28.6052009456265, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25144274, Length=278, Percent_Identity=30.5755395683453, Blast_Score=126, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323470, Length=416, Percent_Identity=30.0480769230769, Blast_Score=173, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6324432, Length=405, Percent_Identity=29.8765432098765, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6324386, Length=459, Percent_Identity=25.7080610021786, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357415, Length=400, Percent_Identity=30.75, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI28574759, Length=440, Percent_Identity=27.7272727272727, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI161085790, Length=441, Percent_Identity=27.6643990929705, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI21356575, Length=345, Percent_Identity=29.5652173913043, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43842; Mature: 43842

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPDFIKYQAQTSPYPLGMEVSHAVGSYIYDTNNKKYLDFVAGVSACTLGHQHPRVNQAI
CCCCEEEEECCCCCCCCCCCHHHHHCCEEEECCCCEEHHHHHHHHHHHCCCCCCHHHHHH
KDQLDKYSHVMVYGEYSQSPAVQYCKLMASLLPESLNKTYLVNSGTEAIEGALKLAKRTT
HHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCC
GRSQLISCHNAYHGNTMGSMSVMGFEERKQAFRPLLPDVDFITFNNEADLEKITTRTAAI
CHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHH
LLETIQGGAGFIQPENNFLQKVRKRCDEVGALMIVDEIQPGFGRTGKLFGFQNYDVIPDI
HHHHHCCCCCEECCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEECCCCCCCCCCC
VVMGKGMGGGMPVGAFTASAEKMDLLTENPKLGHITTFGGHPVIASACLATLQELTETNL
EEEECCCCCCCCCCCEECCHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
MNEALEKEKLFRSLLVHPLIKEVRGKGLMLAAMTETADITNEVILNCQDKGLILFWLLFE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHCCHHHEEEECCCCEEEEEEHHH
GCAIRITPPLTISEEEIKEGCSIILEVMDEIMRKQQA
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPDFIKYQAQTSPYPLGMEVSHAVGSYIYDTNNKKYLDFVAGVSACTLGHQHPRVNQAI
CCCCEEEEECCCCCCCCCCCHHHHHCCEEEECCCCEEHHHHHHHHHHHCCCCCCHHHHHH
KDQLDKYSHVMVYGEYSQSPAVQYCKLMASLLPESLNKTYLVNSGTEAIEGALKLAKRTT
HHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCC
GRSQLISCHNAYHGNTMGSMSVMGFEERKQAFRPLLPDVDFITFNNEADLEKITTRTAAI
CHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHH
LLETIQGGAGFIQPENNFLQKVRKRCDEVGALMIVDEIQPGFGRTGKLFGFQNYDVIPDI
HHHHHCCCCCEECCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEECCCCCCCCCCC
VVMGKGMGGGMPVGAFTASAEKMDLLTENPKLGHITTFGGHPVIASACLATLQELTETNL
EEEECCCCCCCCCCCEECCHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
MNEALEKEKLFRSLLVHPLIKEVRGKGLMLAAMTETADITNEVILNCQDKGLILFWLLFE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHCCHHHEEEECCCCEEEEEEHHH
GCAIRITPPLTISEEEIKEGCSIILEVMDEIMRKQQA
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]