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The map label for this gene is aroE [H]

Identifier: 146300344

GI number: 146300344

Start: 3083460

End: 3084209

Strand: Reverse

Name: aroE [H]

Synonym: Fjoh_2589

Alternate gene names: 146300344

Gene position: 3084209-3083460 (Counterclockwise)

Preceding gene: 146300345

Following gene: 146300343

Centisome position: 50.59

GC content: 32.67

Gene sequence:

>750_bases
ATGATTGGAGTTTTAAAGAGAAGATTTGGCTTATTGGGCCGTAATATTAGTTACTCATTTTCAAAAGGTTATTTTACAGA
AAAATTCAACGATGAAATTTTCGCAGGCAACAGCTACGAAAACTTCGATATTTCTGAAATCAGCCATTTTACCGGATTAT
TAAAAAACAATCCTGATTTGAAAGGTTTAAATGTTACAATTCCATACAAAGAGCAAATTATTCCTTTTCTGGATAAACTT
TCAAAAAAAGCGGCTTTAATTGGTGCTGTAAATACTATTAAATTTACCAAAAACGGAAAATTAAAAGGCTACAACACCGA
TTATTACGGTTTTAAAAAATCATTAAAACCATTACTGGAGCCTCACCATAAAAAAGCTTTGATTTTAGGAACCGGAGGCG
CTTCAAAAGGTGTTGCTTTTGCACTTGATGAACTTGATATTCCATATACTTTTGTTTCGAGAGAAGCCAAAGAAAATATT
ATCGATTATAATTTAATCAACGCAACGACTTTTGATAATTTTCAAATTATCATTAACTGCACTCCTGTTGGCACAAGTCC
TAACGTAGAAGCCTATCCGGATCTGCCTTATGAGTTTTTTACAGAAAAACATATTGCTTACGATTTGATTTACAATCCTG
CAGAAACTCAATTTCTAAAAAATGCAAAAGAAAGAGGCGCAGTAATCAAAAACGGATACGATATGCTTATTTTTCAGGCA
GAGAAAGCCTGGAAGATCTGGAACAAATAA

Upstream 100 bases:

>100_bases
GTTTAAACTTTGATAATTATATACTTATCGAAGATTTATTCCCTGTAGTATGGACAAAAAAGACAGTTAGAAATTACATC
GAAAAACACAGAAAATAAGA

Downstream 100 bases:

>100_bases
AAAAGCTGATTTTCAAGAAGTTAAAGTAATTTTCGTAATTTAGTCTACTCATTTGTAGATAGTTATGAAAATATCACAAT
TTTACTTCTGCATAATTTTT

Product: shikimate dehydrogenase substrate binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MIGVLKRRFGLLGRNISYSFSKGYFTEKFNDEIFAGNSYENFDISEISHFTGLLKNNPDLKGLNVTIPYKEQIIPFLDKL
SKKAALIGAVNTIKFTKNGKLKGYNTDYYGFKKSLKPLLEPHHKKALILGTGGASKGVAFALDELDIPYTFVSREAKENI
IDYNLINATTFDNFQIIINCTPVGTSPNVEAYPDLPYEFFTEKHIAYDLIYNPAETQFLKNAKERGAVIKNGYDMLIFQA
EKAWKIWNK

Sequences:

>Translated_249_residues
MIGVLKRRFGLLGRNISYSFSKGYFTEKFNDEIFAGNSYENFDISEISHFTGLLKNNPDLKGLNVTIPYKEQIIPFLDKL
SKKAALIGAVNTIKFTKNGKLKGYNTDYYGFKKSLKPLLEPHHKKALILGTGGASKGVAFALDELDIPYTFVSREAKENI
IDYNLINATTFDNFQIIINCTPVGTSPNVEAYPDLPYEFFTEKHIAYDLIYNPAETQFLKNAKERGAVIKNGYDMLIFQA
EKAWKIWNK
>Mature_249_residues
MIGVLKRRFGLLGRNISYSFSKGYFTEKFNDEIFAGNSYENFDISEISHFTGLLKNNPDLKGLNVTIPYKEQIIPFLDKL
SKKAALIGAVNTIKFTKNGKLKGYNTDYYGFKKSLKPLLEPHHKKALILGTGGASKGVAFALDELDIPYTFVSREAKENI
IDYNLINATTFDNFQIIINCTPVGTSPNVEAYPDLPYEFFTEKHIAYDLIYNPAETQFLKNAKERGAVIKNGYDMLIFQA
EKAWKIWNK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=202, Percent_Identity=34.1584158415842, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320332, Length=220, Percent_Identity=25, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 28268; Mature: 28268

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGVLKRRFGLLGRNISYSFSKGYFTEKFNDEIFAGNSYENFDISEISHFTGLLKNNPDL
CCCHHHHHHHHHCCCCCEEECCCEECCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCC
KGLNVTIPYKEQIIPFLDKLSKKAALIGAVNTIKFTKNGKLKGYNTDYYGFKKSLKPLLE
CEEEEEECCHHHHHHHHHHHHHHHEEEEEEEEEEEECCCCEECCCCCHHHHHHHHHHHCC
PHHKKALILGTGGASKGVAFALDELDIPYTFVSREAKENIIDYNLINATTFDNFQIIINC
CCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEEEECCEEEEEEE
TPVGTSPNVEAYPDLPYEFFTEKHIAYDLIYNPAETQFLKNAKERGAVIKNGYDMLIFQA
EECCCCCCCCCCCCCCHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCEEECCCEEEEEEC
EKAWKIWNK
CCHHCCCCC
>Mature Secondary Structure
MIGVLKRRFGLLGRNISYSFSKGYFTEKFNDEIFAGNSYENFDISEISHFTGLLKNNPDL
CCCHHHHHHHHHCCCCCEEECCCEECCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCC
KGLNVTIPYKEQIIPFLDKLSKKAALIGAVNTIKFTKNGKLKGYNTDYYGFKKSLKPLLE
CEEEEEECCHHHHHHHHHHHHHHHEEEEEEEEEEEECCCCEECCCCCHHHHHHHHHHHCC
PHHKKALILGTGGASKGVAFALDELDIPYTFVSREAKENIIDYNLINATTFDNFQIIINC
CCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEEEECCEEEEEEE
TPVGTSPNVEAYPDLPYEFFTEKHIAYDLIYNPAETQFLKNAKERGAVIKNGYDMLIFQA
EECCCCCCCCCCCCCCHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCEEECCCEEEEEEC
EKAWKIWNK
CCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA