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The map label for this gene is yngE [H]

Identifier: 146300301

GI number: 146300301

Start: 3030661

End: 3032289

Strand: Reverse

Name: yngE [H]

Synonym: Fjoh_2546

Alternate gene names: 146300301

Gene position: 3032289-3030661 (Counterclockwise)

Preceding gene: 146300306

Following gene: 146300300

Centisome position: 49.74

GC content: 38.86

Gene sequence:

>1629_bases
ATGGATTTAAACTTCAATAAAAACGAAGATCACAATAAACTCTTACTTTCAGAATTAAAACAAAAATTTGCCAAAGTAAA
ATTGGGCGGAGGCGAAAAACGAATTGAAAAATTACATGCCGAAGGAAAAATGACGGCTCGTGAACGTATCGATTATTTAT
TAGATGAAAATTCAAATAGTATTGAAATTGGCGGTTTTGCCGGCGAAGGAATGTACGCTGAACACGGCGGATGTCCGTCT
GGCGGAGTTGTAATTAAAATAGGATACATAAAAGGAAAGCAATGCATTGTGGTTGCGAATGATGCGACGGTAAAAGCCGG
AGCCTGGTTTCCAATAACAGGAAAAAAGAATCTTCGAGCGCAGGAAATTGCAATCGAAAACAGACTTCCAATTATATATT
TAGTAGACAGTGCCGGAGTTTACCTGCCTATGCAGGATGAAATTTTTCCTGACAAAGAACATTTCGGACGCATTTTTAGA
AATAATGCTCAAATGAGCAGTATGGGAATTACACAAATCGCTGCCGTTATGGGAAGCTGTGTTGCCGGAGGTGCTTATCT
GCCCATTATGAGCGATGAAGCTTTAATTGTAGACAAAACAGGCAGTATTTTCCTTGCCGGAAGTTATTTGGTTAAAGCAG
CAATTGGAGAAACTATCGACAACGAAACTCTGGGCGGTGCAACAACACACTGCGAAATTTCTGGAGTTACAGACTATAAA
GCTAAAGATGACAAAGATGCTTTAGATAAAATTAAAAATATTGTAGATAAAATTGGTGATTTTGATAAAGCCGGCTACAG
CCGAATCAAAGCTGAAAAACCTGCTTTAGACCAAAATGACATTTACGGAATTTTACCAAAAGCCAGAACAGATCAATACG
ACATGATGGAAATCATAAAACGTTTGGTTGATAATTCAGAATTTGAAGCGTATAAAGAAGGTTACGGACAATCATTAATA
ACCGGTTATGCCAGAATAGACGGCTGGGCTGTCGGAATTGTGGCGAACCAGCGAAAAGTGGTAAAGACCAAAAAAGGCGA
AATGCAGTTTGGAGGCGTAATTTACTCTGACAGCGCAGACAAAGCAACCCGATTTATTGCAAATTGCAATCAAAAAAAGA
TTCCGCTGGTATTTTTACAAGATGTTACCGGATTTATGGTAGGTTCAAAATCTGAACATGGCGGAATTATTAAAGATGGT
GCTAAAATGGTAAACGCAGTAAGCAATTCTGTTGTACCAAAATTCACAGTAATTGTAGGTAATTCTTATGGTGCAGGAAA
TTATGCGATGTGCGGAAAAGCCTATGATCCAAGATTAATTTTCGCATGGCCAAGTGCAGAACTTGCTGTTATGGGAGGAA
CTCAGGCAGCTAAAGTTTTAGCGCAAATTGAAGCTTCTTCGCTTAAAGCTAAAGGCGAAGTTATTGATGAAGCCAAAGAA
GCAGAATTATTCAATAAAATAAAAGCACGTTACGACGAGCAGACTTCTCCATATTATGCGGCATCAAGATTATGGACAGA
TGCTATTATCGATCCGCTTGATACCCGCAAATGGATCTCAATGGGAATCGAAGCAGCAAACCACGCTCCTATTCAAAAAC
CATTTAATTTGGGAGTTATTCAGGTTTAG

Upstream 100 bases:

>100_bases
AACAGAAATATAAACTTTTTCTTAATTCACAAAGCAATCGGTTTATTTCAATTGATTTTGTAAATTAGCCAACACTATTT
TGTAAAATCAATATTATATC

Downstream 100 bases:

>100_bases
CAGTTTTAAAATTTTGAAAAGCTGTTAAATAAATATCAAAAAACTCATTTTCAGATACTTAAATTAAATATATCATTAAA
AATTAGTAACTTTATATGTA

Product: propionyl-CoA carboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MDLNFNKNEDHNKLLLSELKQKFAKVKLGGGEKRIEKLHAEGKMTARERIDYLLDENSNSIEIGGFAGEGMYAEHGGCPS
GGVVIKIGYIKGKQCIVVANDATVKAGAWFPITGKKNLRAQEIAIENRLPIIYLVDSAGVYLPMQDEIFPDKEHFGRIFR
NNAQMSSMGITQIAAVMGSCVAGGAYLPIMSDEALIVDKTGSIFLAGSYLVKAAIGETIDNETLGGATTHCEISGVTDYK
AKDDKDALDKIKNIVDKIGDFDKAGYSRIKAEKPALDQNDIYGILPKARTDQYDMMEIIKRLVDNSEFEAYKEGYGQSLI
TGYARIDGWAVGIVANQRKVVKTKKGEMQFGGVIYSDSADKATRFIANCNQKKIPLVFLQDVTGFMVGSKSEHGGIIKDG
AKMVNAVSNSVVPKFTVIVGNSYGAGNYAMCGKAYDPRLIFAWPSAELAVMGGTQAAKVLAQIEASSLKAKGEVIDEAKE
AELFNKIKARYDEQTSPYYAASRLWTDAIIDPLDTRKWISMGIEAANHAPIQKPFNLGVIQV

Sequences:

>Translated_542_residues
MDLNFNKNEDHNKLLLSELKQKFAKVKLGGGEKRIEKLHAEGKMTARERIDYLLDENSNSIEIGGFAGEGMYAEHGGCPS
GGVVIKIGYIKGKQCIVVANDATVKAGAWFPITGKKNLRAQEIAIENRLPIIYLVDSAGVYLPMQDEIFPDKEHFGRIFR
NNAQMSSMGITQIAAVMGSCVAGGAYLPIMSDEALIVDKTGSIFLAGSYLVKAAIGETIDNETLGGATTHCEISGVTDYK
AKDDKDALDKIKNIVDKIGDFDKAGYSRIKAEKPALDQNDIYGILPKARTDQYDMMEIIKRLVDNSEFEAYKEGYGQSLI
TGYARIDGWAVGIVANQRKVVKTKKGEMQFGGVIYSDSADKATRFIANCNQKKIPLVFLQDVTGFMVGSKSEHGGIIKDG
AKMVNAVSNSVVPKFTVIVGNSYGAGNYAMCGKAYDPRLIFAWPSAELAVMGGTQAAKVLAQIEASSLKAKGEVIDEAKE
AELFNKIKARYDEQTSPYYAASRLWTDAIIDPLDTRKWISMGIEAANHAPIQKPFNLGVIQV
>Mature_542_residues
MDLNFNKNEDHNKLLLSELKQKFAKVKLGGGEKRIEKLHAEGKMTARERIDYLLDENSNSIEIGGFAGEGMYAEHGGCPS
GGVVIKIGYIKGKQCIVVANDATVKAGAWFPITGKKNLRAQEIAIENRLPIIYLVDSAGVYLPMQDEIFPDKEHFGRIFR
NNAQMSSMGITQIAAVMGSCVAGGAYLPIMSDEALIVDKTGSIFLAGSYLVKAAIGETIDNETLGGATTHCEISGVTDYK
AKDDKDALDKIKNIVDKIGDFDKAGYSRIKAEKPALDQNDIYGILPKARTDQYDMMEIIKRLVDNSEFEAYKEGYGQSLI
TGYARIDGWAVGIVANQRKVVKTKKGEMQFGGVIYSDSADKATRFIANCNQKKIPLVFLQDVTGFMVGSKSEHGGIIKDG
AKMVNAVSNSVVPKFTVIVGNSYGAGNYAMCGKAYDPRLIFAWPSAELAVMGGTQAAKVLAQIEASSLKAKGEVIDEAKE
AELFNKIKARYDEQTSPYYAASRLWTDAIIDPLDTRKWISMGIEAANHAPIQKPFNLGVIQV

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI11545863, Length=530, Percent_Identity=48.4905660377358, Blast_Score=496, Evalue=1e-140,
Organism=Homo sapiens, GI119943100, Length=533, Percent_Identity=32.8330206378987, Blast_Score=246, Evalue=5e-65,
Organism=Homo sapiens, GI295821216, Length=553, Percent_Identity=31.8264014466546, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI310133460, Length=134, Percent_Identity=47.0149253731343, Blast_Score=110, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17552936, Length=528, Percent_Identity=47.7272727272727, Blast_Score=501, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI25147359, Length=542, Percent_Identity=31.549815498155, Blast_Score=245, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI25147362, Length=542, Percent_Identity=31.549815498155, Blast_Score=245, Evalue=5e-65,
Organism=Drosophila melanogaster, GI24586065, Length=538, Percent_Identity=48.1412639405204, Blast_Score=503, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: NA

Molecular weight: Translated: 59067; Mature: 59067

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNFNKNEDHNKLLLSELKQKFAKVKLGGGEKRIEKLHAEGKMTARERIDYLLDENSNS
CCCCCCCCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCE
IEIGGFAGEGMYAEHGGCPSGGVVIKIGYIKGKQCIVVANDATVKAGAWFPITGKKNLRA
EEECCEECCCCEECCCCCCCCCEEEEEEEECCCEEEEEECCCEEECCEEEEECCCCCCCH
QEIAIENRLPIIYLVDSAGVYLPMQDEIFPDKEHFGRIFRNNAQMSSMGITQIAAVMGSC
HHEEHHCCCCEEEEECCCCEEECCCCCCCCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHH
VAGGAYLPIMSDEALIVDKTGSIFLAGSYLVKAAIGETIDNETLGGATTHCEISGVTDYK
HCCCEEEEEECCCEEEEECCCCEEEEHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCC
AKDDKDALDKIKNIVDKIGDFDKAGYSRIKAEKPALDQNDIYGILPKARTDQYDMMEIIK
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHH
RLVDNSEFEAYKEGYGQSLITGYARIDGWAVGIVANQRKVVKTKKGEMQFGGVIYSDSAD
HHHCCCHHHHHHHCCCHHHHHHHHEECCEEEEEEECCCEEEECCCCCEEECCEEEECCHH
KATRFIANCNQKKIPLVFLQDVTGFMVGSKSEHGGIIKDGAKMVNAVSNSVVPKFTVIVG
HHHHHHHCCCCCCCCEEEECCCCHHEECCCCCCCCEEHHHHHHHHHHHCCCCCEEEEEEE
NSYGAGNYAMCGKAYDPRLIFAWPSAELAVMGGTQAAKVLAQIEASSLKAKGEVIDEAKE
CCCCCCCEEECCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHH
AELFNKIKARYDEQTSPYYAASRLWTDAIIDPLDTRKWISMGIEAANHAPIQKPFNLGVI
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCE
QV
EC
>Mature Secondary Structure
MDLNFNKNEDHNKLLLSELKQKFAKVKLGGGEKRIEKLHAEGKMTARERIDYLLDENSNS
CCCCCCCCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCE
IEIGGFAGEGMYAEHGGCPSGGVVIKIGYIKGKQCIVVANDATVKAGAWFPITGKKNLRA
EEECCEECCCCEECCCCCCCCCEEEEEEEECCCEEEEEECCCEEECCEEEEECCCCCCCH
QEIAIENRLPIIYLVDSAGVYLPMQDEIFPDKEHFGRIFRNNAQMSSMGITQIAAVMGSC
HHEEHHCCCCEEEEECCCCEEECCCCCCCCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHH
VAGGAYLPIMSDEALIVDKTGSIFLAGSYLVKAAIGETIDNETLGGATTHCEISGVTDYK
HCCCEEEEEECCCEEEEECCCCEEEEHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCC
AKDDKDALDKIKNIVDKIGDFDKAGYSRIKAEKPALDQNDIYGILPKARTDQYDMMEIIK
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHH
RLVDNSEFEAYKEGYGQSLITGYARIDGWAVGIVANQRKVVKTKKGEMQFGGVIYSDSAD
HHHCCCHHHHHHHCCCHHHHHHHHEECCEEEEEEECCCEEEECCCCCEEECCEEEECCHH
KATRFIANCNQKKIPLVFLQDVTGFMVGSKSEHGGIIKDGAKMVNAVSNSVVPKFTVIVG
HHHHHHHCCCCCCCCEEEECCCCHHEECCCCCCCCEEHHHHHHHHHHHCCCCCEEEEEEE
NSYGAGNYAMCGKAYDPRLIFAWPSAELAVMGGTQAAKVLAQIEASSLKAKGEVIDEAKE
CCCCCCCEEECCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHH
AELFNKIKARYDEQTSPYYAASRLWTDAIIDPLDTRKWISMGIEAANHAPIQKPFNLGVI
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCE
QV
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9387222 [H]