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The map label for this gene is iolS [H]

Identifier: 146300258

GI number: 146300258

Start: 2990091

End: 2991077

Strand: Reverse

Name: iolS [H]

Synonym: Fjoh_2503

Alternate gene names: 146300258

Gene position: 2991077-2990091 (Counterclockwise)

Preceding gene: 146300259

Following gene: 146300257

Centisome position: 49.06

GC content: 36.27

Gene sequence:

>987_bases
ATGAACTACAGAAAACTAGGAAAAACCAATTTTAATATCTCTGAAATCTCTCTGGGAACCTGGCAGGTTGGCGGAAAATG
GGGATCAGGATTTAATGATAAAACAGCCGACGAATTAATAAATACTGCCATAGATAATGGCGTAAATTTTATTGATACGG
CCGATGTTTATGAAAACGGACTAAGCGAAACTGCTGTTGGACGAGTAGTTCGTTCACGATCTGAACGTATTTATGTAGCC
ACAAAATGCGGACGCCAGATTAATCCGCATGTGAATGAAGGCTATCAGCCAAAAGTACTTCAAAAGTTTGTTGAAGACAG
TTTAAAAAGAACTGGATTAGAAACTTTAGATTTAATTCAGCTGCACTGTCCGCCGACAGAAGTATATTACCGTCCTGAAA
TCTTCGAAATGTTTGATCGTTTAAAAGATCAGGGTAAAATTCAAAATTTAGGAGTAAGTGTCGAAAAAGTTGAAGAAGCT
TTAAAAGCAATCGAATACTCTAATGTAACGACTGTTCAGATTATTTTTAACCTGTTTCGTCAGCGTCCGTCGCAATTATT
CTTCTCAGAAGCCAAAAAGAAAGATATTGGAATCATTGCGCGTGTTCCTCTTGCCAGCGGACTTTTAACGGGTAAATTTG
ATGCTAAAACGACTTTTGATGCTCAGGATCATCGTAATTTCAACAGAAACGGAGATGCTTTTGATAAAGGCGAAACTTTT
TCAGGAATCGATTATGATTTAGGTTTAAAAGCTGTTGAAGAATTAAAAGCACTTTTTCCTGAAACTACAAACCTCGCTCC
TATTGCACTGCAATGGATTTTAAGTTTTAACGAAATAAGCTGTATTATTCCGGGAGCTTCAAAAGAAAGTCATGTACTTT
CCAATTTATCTGTTTATGATCTGCCAAAATTATCTCCTGAGAAAATTTTGGCTATGAATAAAATTTACGAAGAGTATATT
AAACCTTCTGTGCATCATCTTTGGTAG

Upstream 100 bases:

>100_bases
AAACTACAACCCTTATACCCAAAAAAGACGCACTGCTGTGCGCCTCTATAAAAAACCTTTACACCTTTGTACCTCTGAAC
CTTTGTAACTTAAAAAGAAA

Downstream 100 bases:

>100_bases
CTTTATGCTTCTAAGATATTAAGCAGCTGAGTTTTTAAGTTTTTCCAGGCTTAGAAACTCAGTTTTTATTTTTCTTCCTG
ACGCAACCATTTTACTAAAG

Product: aldo/keto reductase

Products: NA

Alternate protein names: AKR11A; Vegetative protein 147; VEG147 [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MNYRKLGKTNFNISEISLGTWQVGGKWGSGFNDKTADELINTAIDNGVNFIDTADVYENGLSETAVGRVVRSRSERIYVA
TKCGRQINPHVNEGYQPKVLQKFVEDSLKRTGLETLDLIQLHCPPTEVYYRPEIFEMFDRLKDQGKIQNLGVSVEKVEEA
LKAIEYSNVTTVQIIFNLFRQRPSQLFFSEAKKKDIGIIARVPLASGLLTGKFDAKTTFDAQDHRNFNRNGDAFDKGETF
SGIDYDLGLKAVEELKALFPETTNLAPIALQWILSFNEISCIIPGASKESHVLSNLSVYDLPKLSPEKILAMNKIYEEYI
KPSVHHLW

Sequences:

>Translated_328_residues
MNYRKLGKTNFNISEISLGTWQVGGKWGSGFNDKTADELINTAIDNGVNFIDTADVYENGLSETAVGRVVRSRSERIYVA
TKCGRQINPHVNEGYQPKVLQKFVEDSLKRTGLETLDLIQLHCPPTEVYYRPEIFEMFDRLKDQGKIQNLGVSVEKVEEA
LKAIEYSNVTTVQIIFNLFRQRPSQLFFSEAKKKDIGIIARVPLASGLLTGKFDAKTTFDAQDHRNFNRNGDAFDKGETF
SGIDYDLGLKAVEELKALFPETTNLAPIALQWILSFNEISCIIPGASKESHVLSNLSVYDLPKLSPEKILAMNKIYEEYI
KPSVHHLW
>Mature_328_residues
MNYRKLGKTNFNISEISLGTWQVGGKWGSGFNDKTADELINTAIDNGVNFIDTADVYENGLSETAVGRVVRSRSERIYVA
TKCGRQINPHVNEGYQPKVLQKFVEDSLKRTGLETLDLIQLHCPPTEVYYRPEIFEMFDRLKDQGKIQNLGVSVEKVEEA
LKAIEYSNVTTVQIIFNLFRQRPSQLFFSEAKKKDIGIIARVPLASGLLTGKFDAKTTFDAQDHRNFNRNGDAFDKGETF
SGIDYDLGLKAVEELKALFPETTNLAPIALQWILSFNEISCIIPGASKESHVLSNLSVYDLPKLSPEKILAMNKIYEEYI
KPSVHHLW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=333, Percent_Identity=26.4264264264264, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI27436971, Length=333, Percent_Identity=24.9249249249249, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4504825, Length=330, Percent_Identity=25.7575757575758, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI27436962, Length=320, Percent_Identity=25.3125, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI27436964, Length=320, Percent_Identity=25.3125, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI27436966, Length=320, Percent_Identity=25, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI87081735, Length=338, Percent_Identity=26.9230769230769, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788070, Length=317, Percent_Identity=25.5520504731861, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789375, Length=317, Percent_Identity=24.9211356466877, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI212645785, Length=331, Percent_Identity=21.1480362537764, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640980, Length=347, Percent_Identity=24.4956772334294, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45549126, Length=347, Percent_Identity=24.4956772334294, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24646155, Length=220, Percent_Identity=27.7272727272727, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646159, Length=185, Percent_Identity=27.5675675675676, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37032; Mature: 37032

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYRKLGKTNFNISEISLGTWQVGGKWGSGFNDKTADELINTAIDNGVNFIDTADVYENG
CCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEECHHHHHCC
LSETAVGRVVRSRSERIYVATKCGRQINPHVNEGYQPKVLQKFVEDSLKRTGLETLDLIQ
CHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHEEE
LHCPPTEVYYRPEIFEMFDRLKDQGKIQNLGVSVEKVEEALKAIEYSNVTTVQIIFNLFR
EECCCCCEEECCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
QRPSQLFFSEAKKKDIGIIARVPLASGLLTGKFDAKTTFDAQDHRNFNRNGDAFDKGETF
HCHHHHHHHHHCCCCCCEEEECCHHCCCEECCCCCCCCCCCHHCCCCCCCCCCCCCCCCC
SGIDYDLGLKAVEELKALFPETTNLAPIALQWILSFNEISCIIPGASKESHVLSNLSVYD
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCHHHHHCCCCCC
LPKLSPEKILAMNKIYEEYIKPSVHHLW
CCCCCHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure
MNYRKLGKTNFNISEISLGTWQVGGKWGSGFNDKTADELINTAIDNGVNFIDTADVYENG
CCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEECHHHHHCC
LSETAVGRVVRSRSERIYVATKCGRQINPHVNEGYQPKVLQKFVEDSLKRTGLETLDLIQ
CHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHEEE
LHCPPTEVYYRPEIFEMFDRLKDQGKIQNLGVSVEKVEEALKAIEYSNVTTVQIIFNLFR
EECCCCCEEECCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
QRPSQLFFSEAKKKDIGIIARVPLASGLLTGKFDAKTTFDAQDHRNFNRNGDAFDKGETF
HCHHHHHHHHHCCCCCCEEEECCHHCCCEECCCCCCCCCCCHHCCCCCCCCCCCCCCCCC
SGIDYDLGLKAVEELKALFPETTNLAPIALQWILSFNEISCIIPGASKESHVLSNLSVYD
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCHHHHHCCCCCC
LPKLSPEKILAMNKIYEEYIKPSVHHLW
CCCCCHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 9298659 [H]