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The map label for this gene is ygcA [C]

Identifier: 146300255

GI number: 146300255

Start: 2986848

End: 2988260

Strand: Reverse

Name: ygcA [C]

Synonym: Fjoh_2500

Alternate gene names: 146300255

Gene position: 2988260-2986848 (Counterclockwise)

Preceding gene: 146300257

Following gene: 146300254

Centisome position: 49.01

GC content: 35.03

Gene sequence:

>1413_bases
ATGGGAAGAAAAAATACAGACAAAGTTGTCTTTCATCAAATTCAGGTTCTTGATGCCGGAGCCAAGGGAGTATCAGTAGC
AAAAGCTCCTGACGGAAAAGTTATCTTTATTCCAAATGTCGTTCCTGGAGATGTTGTTGATGTACAAACATTCAAAAAAA
GAAAAGCATATTACGAAGGAAAAGCCGTAAAATTTCACGAATTATCAGAACATCGTGTAGATCCTATCTGCGAACATTTT
GGTGTTTGCGGCGGATGCAAATGGCAGAATATGAAATACAGCCAGCAGCTGTATTACAAACAAAACGAAGTAAAAAATCA
TTTACAGCGTATTGGAAAAGTTGAATTGCCGGAATTTGAAACTATTTTGGGTTCGGAAAAACAGTTTTTTTACAGAAATA
AAATGGAATTTTCGTTTTCTAACAGCCGTTGGTTAACCGAAAAAGAAATAGGAAGCACTGAAGATTTAGGAAACAGAAAT
GCATTAGGATTTCATATTCCAAAAATGTGGGATAAGATTCTGGACATCGAAAAATGTCATTTACAGGAAGATCCGTCAAA
TGCTATTAGAAACGAAATTAGAGCTTTTGCCAACGAGCATAATTTAGCTTTTTTTAATCCAAGAGAACATTCCGGACTTT
TAAGAACTTTAATGATACGTACGGCTTCAACCGGAGAAATCATGGTTTTGATCCAGTTTTTTGAAGATGATAAAGCAAAC
CGCGAATTGGTTTTAGATCATTTATACGAGAAATTTCCGCAGATTACTTCATTACAATATGTGGTAAATGCCAAACAAAA
CGATACTATTTACGATCAGGATATAAAACTTTACAAAGGAAGAAATTATATCTTAGAAGAAATGGAAGGCTTAAAATTCA
GCATTAATGCTAAATCTTTTTACCAAACCAACTCTGATCAGGCTTACGAATTATACAAAATTACACGTGATTATGCAGGA
CTAACAGGAGAAGAAACTGTTTATGACTTGTATACAGGAACAGGAACTATTGCACAGTTCGTTTCTAAAAAAGCAAAAAA
AGTAATTGGTGTAGAAAGTGTTCCTGAGGCAATTTTAGACGCTAAAGCAAATGCAGAACGCAATAATATTACCAATTGTG
AGTTTTTTGTTGGAGACATGAAAGTCGTATTCAACGAAGCTTTTATTGCACAGCACGGAAAACCAGATGTTATTATTACA
GATCCTCCAAGAGACGGAATGCACGCTGCGGTTATCGATCAGATTTTAAAAATTGCGCCTAAAAAAGTAGTTTATGTAAG
CTGTAATTCTGCAACACAAGCACGTGATTTAGCTTTAATGGACGAAAAATACAAAGTAACACGTGTACGTCCGGTTGATA
TGTTCCCTCAAACGCATCATGTTGAAAATGTTGTACTTTTAGAACTTCGATAA

Upstream 100 bases:

>100_bases
AGTTAACTTTTAAAGTTAATTAAACTAGCAAATTACATAATTTGATAAAATATTATGAAAATAAAATTTGTAAAAGTTTA
CAAAGGCTTATTTTTGCGCT

Downstream 100 bases:

>100_bases
TTATAAAACTGTAAATGAAAAAAATAATCTCTCTTTTATTACTTTTTACTTTTGGCTTGTCCAGCTGTGAGAAAGATGAT
ATTTGCGACGCAAATACGCC

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MGRKNTDKVVFHQIQVLDAGAKGVSVAKAPDGKVIFIPNVVPGDVVDVQTFKKRKAYYEGKAVKFHELSEHRVDPICEHF
GVCGGCKWQNMKYSQQLYYKQNEVKNHLQRIGKVELPEFETILGSEKQFFYRNKMEFSFSNSRWLTEKEIGSTEDLGNRN
ALGFHIPKMWDKILDIEKCHLQEDPSNAIRNEIRAFANEHNLAFFNPREHSGLLRTLMIRTASTGEIMVLIQFFEDDKAN
RELVLDHLYEKFPQITSLQYVVNAKQNDTIYDQDIKLYKGRNYILEEMEGLKFSINAKSFYQTNSDQAYELYKITRDYAG
LTGEETVYDLYTGTGTIAQFVSKKAKKVIGVESVPEAILDAKANAERNNITNCEFFVGDMKVVFNEAFIAQHGKPDVIIT
DPPRDGMHAAVIDQILKIAPKKVVYVSCNSATQARDLALMDEKYKVTRVRPVDMFPQTHHVENVVLLELR

Sequences:

>Translated_470_residues
MGRKNTDKVVFHQIQVLDAGAKGVSVAKAPDGKVIFIPNVVPGDVVDVQTFKKRKAYYEGKAVKFHELSEHRVDPICEHF
GVCGGCKWQNMKYSQQLYYKQNEVKNHLQRIGKVELPEFETILGSEKQFFYRNKMEFSFSNSRWLTEKEIGSTEDLGNRN
ALGFHIPKMWDKILDIEKCHLQEDPSNAIRNEIRAFANEHNLAFFNPREHSGLLRTLMIRTASTGEIMVLIQFFEDDKAN
RELVLDHLYEKFPQITSLQYVVNAKQNDTIYDQDIKLYKGRNYILEEMEGLKFSINAKSFYQTNSDQAYELYKITRDYAG
LTGEETVYDLYTGTGTIAQFVSKKAKKVIGVESVPEAILDAKANAERNNITNCEFFVGDMKVVFNEAFIAQHGKPDVIIT
DPPRDGMHAAVIDQILKIAPKKVVYVSCNSATQARDLALMDEKYKVTRVRPVDMFPQTHHVENVVLLELR
>Mature_469_residues
GRKNTDKVVFHQIQVLDAGAKGVSVAKAPDGKVIFIPNVVPGDVVDVQTFKKRKAYYEGKAVKFHELSEHRVDPICEHFG
VCGGCKWQNMKYSQQLYYKQNEVKNHLQRIGKVELPEFETILGSEKQFFYRNKMEFSFSNSRWLTEKEIGSTEDLGNRNA
LGFHIPKMWDKILDIEKCHLQEDPSNAIRNEIRAFANEHNLAFFNPREHSGLLRTLMIRTASTGEIMVLIQFFEDDKANR
ELVLDHLYEKFPQITSLQYVVNAKQNDTIYDQDIKLYKGRNYILEEMEGLKFSINAKSFYQTNSDQAYELYKITRDYAGL
TGEETVYDLYTGTGTIAQFVSKKAKKVIGVESVPEAILDAKANAERNNITNCEFFVGDMKVVFNEAFIAQHGKPDVIITD
PPRDGMHAAVIDQILKIAPKKVVYVSCNSATQARDLALMDEKYKVTRVRPVDMFPQTHHVENVVLLELR

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=430, Percent_Identity=28.3720930232558, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI51173878, Length=430, Percent_Identity=28.3720930232558, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI269784678, Length=363, Percent_Identity=26.4462809917355, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI269784680, Length=363, Percent_Identity=26.4462809917355, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI269784676, Length=363, Percent_Identity=26.4462809917355, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI20149688, Length=363, Percent_Identity=26.4462809917355, Blast_Score=119, Evalue=5e-27,
Organism=Escherichia coli, GI1789148, Length=466, Percent_Identity=26.8240343347639, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1787083, Length=398, Percent_Identity=26.1306532663317, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1790403, Length=181, Percent_Identity=27.6243093922652, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997438, Length=165, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322909, Length=427, Percent_Identity=25.9953161592506, Blast_Score=106, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24666579, Length=411, Percent_Identity=32.6034063260341, Blast_Score=152, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 53872; Mature: 53741

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50926 TRAM ; PS01230 TRMA_1 ; PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRKNTDKVVFHQIQVLDAGAKGVSVAKAPDGKVIFIPNVVPGDVVDVQTFKKRKAYYEG
CCCCCCCCEEEEEEEEEECCCCCCEEEECCCCCEEEECCCCCCCEEEHHHHHHHHHHHCC
KAVKFHELSEHRVDPICEHFGVCGGCKWQNMKYSQQLYYKQNEVKNHLQRIGKVELPEFE
CCEEEECCHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHH
TILGSEKQFFYRNKMEFSFSNSRWLTEKEIGSTEDLGNRNALGFHIPKMWDKILDIEKCH
HHHCCCCCEEEECCEEEEECCCCCCCHHHCCCCCCCCCCCCCEEECHHHHHHHHCHHHHH
LQEDPSNAIRNEIRAFANEHNLAFFNPREHSGLLRTLMIRTASTGEIMVLIQFFEDDKAN
CCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC
RELVLDHLYEKFPQITSLQYVVNAKQNDTIYDQDIKLYKGRNYILEEMEGLKFSINAKSF
HHHHHHHHHHHCCCCEEEEEEEECCCCCCEECCCEEEECCCHHHHHHCCCCEEEECCHHE
YQTNSDQAYELYKITRDYAGLTGEETVYDLYTGTGTIAQFVSKKAKKVIGVESVPEAILD
EECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHH
AKANAERNNITNCEFFVGDMKVVFNEAFIAQHGKPDVIITDPPRDGMHAAVIDQILKIAP
CCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCC
KKVVYVSCNSATQARDLALMDEKYKVTRVRPVDMFPQTHHVENVVLLELR
CEEEEEEECCCCCHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
GRKNTDKVVFHQIQVLDAGAKGVSVAKAPDGKVIFIPNVVPGDVVDVQTFKKRKAYYEG
CCCCCCCEEEEEEEEEECCCCCCEEEECCCCCEEEECCCCCCCEEEHHHHHHHHHHHCC
KAVKFHELSEHRVDPICEHFGVCGGCKWQNMKYSQQLYYKQNEVKNHLQRIGKVELPEFE
CCEEEECCHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHH
TILGSEKQFFYRNKMEFSFSNSRWLTEKEIGSTEDLGNRNALGFHIPKMWDKILDIEKCH
HHHCCCCCEEEECCEEEEECCCCCCCHHHCCCCCCCCCCCCCEEECHHHHHHHHCHHHHH
LQEDPSNAIRNEIRAFANEHNLAFFNPREHSGLLRTLMIRTASTGEIMVLIQFFEDDKAN
CCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC
RELVLDHLYEKFPQITSLQYVVNAKQNDTIYDQDIKLYKGRNYILEEMEGLKFSINAKSF
HHHHHHHHHHHCCCCEEEEEEEECCCCCCEECCCEEEECCCHHHHHHCCCCEEEECCHHE
YQTNSDQAYELYKITRDYAGLTGEETVYDLYTGTGTIAQFVSKKAKKVIGVESVPEAILD
EECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHH
AKANAERNNITNCEFFVGDMKVVFNEAFIAQHGKPDVIITDPPRDGMHAAVIDQILKIAP
CCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCC
KKVVYVSCNSATQARDLALMDEKYKVTRVRPVDMFPQTHHVENVVLLELR
CEEEEEEECCCCCHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]