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The map label for this gene is pyrC [H]

Identifier: 146300204

GI number: 146300204

Start: 2931782

End: 2933032

Strand: Reverse

Name: pyrC [H]

Synonym: Fjoh_2449

Alternate gene names: 146300204

Gene position: 2933032-2931782 (Counterclockwise)

Preceding gene: 146300205

Following gene: 146300203

Centisome position: 48.11

GC content: 36.29

Gene sequence:

>1251_bases
ATGAAAATAATCATCAAAAGCGCCAAAATTATCGACTCAAAAAGTCCGTTTCACAACCAGACCGTTGATCTTTTAATTGC
AGATGGTTTAATAGAAAAAATAGGAGTTTCTCTTCCCGATGATGGTGCCGAAATAGTTCGATTTGATGATCTGTATGTTT
CTCAGGGATGGTTTGACAGCAGTGTTTCTCTTGGAGAACCTGGTTACGAAGACAGAGAAACCATTGCAAACGGACTTAAC
GTTGCTGCAAAAAGCGGTTTTACAGCAATTGGTTTACAGCCAAACTCCTTACCTGTTATCGACAACCAGTCGCAGGTAAG
TTTTGTAAAAAACAAAGCAAATGGTTTTGCGACAGAAATTTTCCCAATTGGAGCTTTAACCAAAGCAAGTGAAGGAAAAG
ATATGGCAGAACTTTTTGATATGAAAAACGCCGGCGCAATCGCTTTTGGAGATTATAACAAAAGTATCGACAACGCTAAT
ATCCTAAAGATCGCTTTGCAGTATGTACAAGATTTTGACGGATTGGTAATTGCATATTCGCAAGACCCGAATATTAAAGG
AAACGGCGTTGCAAACGAAGGAATCGTTTCTACAAGATTAGGTTTAAAAGGAATTCCAAATCTAGCCGAAGAACTGCAAA
TTTCAAGAAACTTATTTTTATTGGAATATACAGGCGGAAAACTTCACATTCCAACTATTTCAACAGCAAAATCAGTAGAA
TTAATTAGAGAAGCTAAAGCTAAAGGCTTAAATGTAACAGCAAGCGCATCTGTACACCATTTGGTTTTAACCGATGAGAA
ACTAGACGGTTTTGATACTCGTTTTAAAGTTACGCCGCCATTAAGAACTGAGGTTGACAGACAGGCTTTACTAAACGGAA
TCGCCGATGGAACTATTGACATGATTACTTCTGACCACAACCCAATTGATATTGAATTCAAAAAAATGGAATTTGATACG
GCCAAAAACGGAACAATTGGCTTAGAAAGTGCTTTTGGAGCATTATTAACCGTTTTACCAGTTGAAACTATAGTTGCAAA
ACTAACTGCAGCAAGAACGGTTTTTGGTCTTGAAAATCATACTATTCAGGAAGGAGCAAAAGCAAATATCACTTTATTTA
CAACCGAAGGTAAGTCAACTTTTACGAAAGAAAACATTCTTTCAAAATCTAAAAATTCTGCTTTTTTAGGAACTGAACTT
AAAGGTTCTGTGTACGGAATTTTAAATCAAAATCAACTTGTTACAAAATAA

Upstream 100 bases:

>100_bases
TTAACTTAATTCTTCATGGTTCAAAAAAATTAAGCACTAATGTTTTAAAAATAATTTTACTTTTTACAGAAATCATTTTA
CGACAAAAAAATATCTACAT

Downstream 100 bases:

>100_bases
TACAATGAACAATACAATCGAAGAGGGAAAATCAATCGCAATTACCAGTTATATTTTAATTATTGGTGTTTTGATTGCAA
TGTCTATGAATTCTGAAAAT

Product: amidohydrolase

Products: NA

Alternate protein names: DHOase [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MKIIIKSAKIIDSKSPFHNQTVDLLIADGLIEKIGVSLPDDGAEIVRFDDLYVSQGWFDSSVSLGEPGYEDRETIANGLN
VAAKSGFTAIGLQPNSLPVIDNQSQVSFVKNKANGFATEIFPIGALTKASEGKDMAELFDMKNAGAIAFGDYNKSIDNAN
ILKIALQYVQDFDGLVIAYSQDPNIKGNGVANEGIVSTRLGLKGIPNLAEELQISRNLFLLEYTGGKLHIPTISTAKSVE
LIREAKAKGLNVTASASVHHLVLTDEKLDGFDTRFKVTPPLRTEVDRQALLNGIADGTIDMITSDHNPIDIEFKKMEFDT
AKNGTIGLESAFGALLTVLPVETIVAKLTAARTVFGLENHTIQEGAKANITLFTTEGKSTFTKENILSKSKNSAFLGTEL
KGSVYGILNQNQLVTK

Sequences:

>Translated_416_residues
MKIIIKSAKIIDSKSPFHNQTVDLLIADGLIEKIGVSLPDDGAEIVRFDDLYVSQGWFDSSVSLGEPGYEDRETIANGLN
VAAKSGFTAIGLQPNSLPVIDNQSQVSFVKNKANGFATEIFPIGALTKASEGKDMAELFDMKNAGAIAFGDYNKSIDNAN
ILKIALQYVQDFDGLVIAYSQDPNIKGNGVANEGIVSTRLGLKGIPNLAEELQISRNLFLLEYTGGKLHIPTISTAKSVE
LIREAKAKGLNVTASASVHHLVLTDEKLDGFDTRFKVTPPLRTEVDRQALLNGIADGTIDMITSDHNPIDIEFKKMEFDT
AKNGTIGLESAFGALLTVLPVETIVAKLTAARTVFGLENHTIQEGAKANITLFTTEGKSTFTKENILSKSKNSAFLGTEL
KGSVYGILNQNQLVTK
>Mature_416_residues
MKIIIKSAKIIDSKSPFHNQTVDLLIADGLIEKIGVSLPDDGAEIVRFDDLYVSQGWFDSSVSLGEPGYEDRETIANGLN
VAAKSGFTAIGLQPNSLPVIDNQSQVSFVKNKANGFATEIFPIGALTKASEGKDMAELFDMKNAGAIAFGDYNKSIDNAN
ILKIALQYVQDFDGLVIAYSQDPNIKGNGVANEGIVSTRLGLKGIPNLAEELQISRNLFLLEYTGGKLHIPTISTAKSVE
LIREAKAKGLNVTASASVHHLVLTDEKLDGFDTRFKVTPPLRTEVDRQALLNGIADGTIDMITSDHNPIDIEFKKMEFDT
AKNGTIGLESAFGALLTVLPVETIVAKLTAARTVFGLENHTIQEGAKANITLFTTEGKSTFTKENILSKSKNSAFLGTEL
KGSVYGILNQNQLVTK

Specific function: Involved In The Anaerobic Utilization Of Allantoin. [C]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786722, Length=423, Percent_Identity=25.0591016548463, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6322218, Length=382, Percent_Identity=24.6073298429319, Blast_Score=106, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR004722
- InterPro:   IPR002195
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.3 [H]

Molecular weight: Translated: 44837; Mature: 44837

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIIKSAKIIDSKSPFHNQTVDLLIADGLIEKIGVSLPDDGAEIVRFDDLYVSQGWFDS
CEEEEECEEEECCCCCCCCCEEEEEEECCHHHHHCCCCCCCCCEEEEEEEEEEECCCCCC
SVSLGEPGYEDRETIANGLNVAAKSGFTAIGLQPNSLPVIDNQSQVSFVKNKANGFATEI
CCCCCCCCCCHHHHHHHCCCCHHCCCCEEEECCCCCCCEECCCCHHHHHHHCCCCCEEEE
FPIGALTKASEGKDMAELFDMKNAGAIAFGDYNKSIDNANILKIALQYVQDFDGLVIAYS
EECCCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEC
QDPNIKGNGVANEGIVSTRLGLKGIPNLAEELQISRNLFLLEYTGGKLHIPTISTAKSVE
CCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHH
LIREAKAKGLNVTASASVHHLVLTDEKLDGFDTRFKVTPPLRTEVDRQALLNGIADGTID
HHHHHHHCCCEEEECCCEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEE
MITSDHNPIDIEFKKMEFDTAKNGTIGLESAFGALLTVLPVETIVAKLTAARTVFGLENH
EEECCCCCEEEEEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
TIQEGAKANITLFTTEGKSTFTKENILSKSKNSAFLGTELKGSVYGILNQNQLVTK
CCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCEECCC
>Mature Secondary Structure
MKIIIKSAKIIDSKSPFHNQTVDLLIADGLIEKIGVSLPDDGAEIVRFDDLYVSQGWFDS
CEEEEECEEEECCCCCCCCCEEEEEEECCHHHHHCCCCCCCCCEEEEEEEEEEECCCCCC
SVSLGEPGYEDRETIANGLNVAAKSGFTAIGLQPNSLPVIDNQSQVSFVKNKANGFATEI
CCCCCCCCCCHHHHHHHCCCCHHCCCCEEEECCCCCCCEECCCCHHHHHHHCCCCCEEEE
FPIGALTKASEGKDMAELFDMKNAGAIAFGDYNKSIDNANILKIALQYVQDFDGLVIAYS
EECCCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEC
QDPNIKGNGVANEGIVSTRLGLKGIPNLAEELQISRNLFLLEYTGGKLHIPTISTAKSVE
CCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHH
LIREAKAKGLNVTASASVHHLVLTDEKLDGFDTRFKVTPPLRTEVDRQALLNGIADGTID
HHHHHHHCCCEEEECCCEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEE
MITSDHNPIDIEFKKMEFDTAKNGTIGLESAFGALLTVLPVETIVAKLTAARTVFGLENH
EEECCCCCEEEEEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
TIQEGAKANITLFTTEGKSTFTKENILSKSKNSAFLGTELKGSVYGILNQNQLVTK
CCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA