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The map label for this gene is nrnA [H]

Identifier: 146300125

GI number: 146300125

Start: 2840076

End: 2841080

Strand: Reverse

Name: nrnA [H]

Synonym: Fjoh_2370

Alternate gene names: 146300125

Gene position: 2841080-2840076 (Counterclockwise)

Preceding gene: 146300126

Following gene: 146300124

Centisome position: 46.6

GC content: 35.02

Gene sequence:

>1005_bases
ATGAAAATACAAGATATTCAGGCAATTCAATTATTGCTTGCTGCTCCAAAGAAAATTGTAATAATTCCGCACAGAGGCCC
AGACGGCGACGCTATGGGTTCTACTCTTGCATTATACCATTTTTTATTAAAAAACAATCATCAGGCAACAGTAATTGCTC
CTAATGATTTTCCTGATTTTCTGGCTTGGCTTCCAGGTTCTGAAACGGTAAAAATATTTGAAAAAGACACTGAAAACTGC
ATCAAAATATTAGAAGAAGCCGAATTAATTTTTACGCTTGATTTTAATGCTTTTCACCGAACAGGCGAAATGGAACATAC
GTTAGCCAGATTAACGGCTCCGTATATCATGATCGATCATCATGAAAAACCGCATGATTATGCCCTTTACACATATTCTG
ACCCAACATACGGATCGACTTGTGAAATGGTTTACAACTTTATTACTTTCCTGAACAAAAAGGAAGATATTGATAAAAAT
ATTGCAACCTGCATATATACTGGAATTTTAACTGATTCCGGCTCTTTTCGCTTTCCGGGAACTACAGGAAACACACACCG
AATTATTGCTGAACTAATTGACTTAGGAGTTGAGAATACTCAAATTCCGGTTTTGTTATACGATAACAGCTCATTCAGCC
GTTTGCAGTTATTAGGCCGTGCTTTACAAAACATGAAAATTTTTGAAGAGCATAAAACGTCTTACATGACTTTGACTCAG
GAAGAGTTAGATTCTTTTAATTATGTAAAAGGCGATACCGAAGGAATTGTTAATTATGGTTTAAGCATACGCGGAATTGT
TTTTACAGCTATCTTTATCGAAAATAGAGACGAAAAAATAATTAAAATTTCTTTCCGTTCTCAAGGAGGATTTGATGTTA
ACCAATTTGCAAGAGACCATTTTAATGGAGGCGGACACATAAATGCAGCTGGCGGAAGATCTGAAGTTTCAATGGAAGAA
ACAGTTAAAAAATTCGAAGATTTAGTAACTAAACTAAAATTATAA

Upstream 100 bases:

>100_bases
TTTGAATTTTAAATTCAAAAACTGAACTGATTACTGCGACTGTGACTGAAAACTAAAATTATTTTCAGCATTACATTAAA
AAAATGTAAATTCGCACACT

Downstream 100 bases:

>100_bases
AACCAATATGAACTACTTAAAAATCAGCATTTATTCACTGCTTTTTGCAGTTTTATTGGCGGGCTGTAAGCATCATGAAG
AAGCGCGCAGGCCAATTTCC

Product: phosphoesterase domain-containing protein

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKIQDIQAIQLLLAAPKKIVIIPHRGPDGDAMGSTLALYHFLLKNNHQATVIAPNDFPDFLAWLPGSETVKIFEKDTENC
IKILEEAELIFTLDFNAFHRTGEMEHTLARLTAPYIMIDHHEKPHDYALYTYSDPTYGSTCEMVYNFITFLNKKEDIDKN
IATCIYTGILTDSGSFRFPGTTGNTHRIIAELIDLGVENTQIPVLLYDNSSFSRLQLLGRALQNMKIFEEHKTSYMTLTQ
EELDSFNYVKGDTEGIVNYGLSIRGIVFTAIFIENRDEKIIKISFRSQGGFDVNQFARDHFNGGGHINAAGGRSEVSMEE
TVKKFEDLVTKLKL

Sequences:

>Translated_334_residues
MKIQDIQAIQLLLAAPKKIVIIPHRGPDGDAMGSTLALYHFLLKNNHQATVIAPNDFPDFLAWLPGSETVKIFEKDTENC
IKILEEAELIFTLDFNAFHRTGEMEHTLARLTAPYIMIDHHEKPHDYALYTYSDPTYGSTCEMVYNFITFLNKKEDIDKN
IATCIYTGILTDSGSFRFPGTTGNTHRIIAELIDLGVENTQIPVLLYDNSSFSRLQLLGRALQNMKIFEEHKTSYMTLTQ
EELDSFNYVKGDTEGIVNYGLSIRGIVFTAIFIENRDEKIIKISFRSQGGFDVNQFARDHFNGGGHINAAGGRSEVSMEE
TVKKFEDLVTKLKL
>Mature_334_residues
MKIQDIQAIQLLLAAPKKIVIIPHRGPDGDAMGSTLALYHFLLKNNHQATVIAPNDFPDFLAWLPGSETVKIFEKDTENC
IKILEEAELIFTLDFNAFHRTGEMEHTLARLTAPYIMIDHHEKPHDYALYTYSDPTYGSTCEMVYNFITFLNKKEDIDKN
IATCIYTGILTDSGSFRFPGTTGNTHRIIAELIDLGVENTQIPVLLYDNSSFSRLQLLGRALQNMKIFEEHKTSYMTLTQ
EELDSFNYVKGDTEGIVNYGLSIRGIVFTAIFIENRDEKIIKISFRSQGGFDVNQFARDHFNGGGHINAAGGRSEVSMEE
TVKKFEDLVTKLKL

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 37789; Mature: 37789

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIQDIQAIQLLLAAPKKIVIIPHRGPDGDAMGSTLALYHFLLKNNHQATVIAPNDFPDF
CCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHH
LAWLPGSETVKIFEKDTENCIKILEEAELIFTLDFNAFHRTGEMEHTLARLTAPYIMIDH
HHHCCCCCEEEEEECCHHHHHHHHHCCEEEEEEECHHHHCCCCHHHHHHHHCCCEEEEEC
HEKPHDYALYTYSDPTYGSTCEMVYNFITFLNKKEDIDKNIATCIYTGILTDSGSFRFPG
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEECCCCEECCC
TTGNTHRIIAELIDLGVENTQIPVLLYDNSSFSRLQLLGRALQNMKIFEEHKTSYMTLTQ
CCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCHHHHHHCCCEEEEEH
EELDSFNYVKGDTEGIVNYGLSIRGIVFTAIFIENRDEKIIKISFRSQGGFDVNQFARDH
HHHCCCCCCCCCCCHHHHCCCEEHEEEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHH
FNGGGHINAAGGRSEVSMEETVKKFEDLVTKLKL
CCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIQDIQAIQLLLAAPKKIVIIPHRGPDGDAMGSTLALYHFLLKNNHQATVIAPNDFPDF
CCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHH
LAWLPGSETVKIFEKDTENCIKILEEAELIFTLDFNAFHRTGEMEHTLARLTAPYIMIDH
HHHCCCCCEEEEEECCHHHHHHHHHCCEEEEEEECHHHHCCCCHHHHHHHHCCCEEEEEC
HEKPHDYALYTYSDPTYGSTCEMVYNFITFLNKKEDIDKNIATCIYTGILTDSGSFRFPG
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEECCCCEECCC
TTGNTHRIIAELIDLGVENTQIPVLLYDNSSFSRLQLLGRALQNMKIFEEHKTSYMTLTQ
CCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCHHHHHHCCCEEEEEH
EELDSFNYVKGDTEGIVNYGLSIRGIVFTAIFIENRDEKIIKISFRSQGGFDVNQFARDH
HHHCCCCCCCCCCCHHHHCCCEEHEEEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHH
FNGGGHINAAGGRSEVSMEETVKKFEDLVTKLKL
CCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]