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The map label for this gene is traD [H]

Identifier: 146284634

GI number: 146284634

Start: 132674

End: 135196

Strand: Direct

Name: traD [H]

Synonym: Ent638_4308

Alternate gene names: 146284634

Gene position: 132674-135196 (Clockwise)

Preceding gene: 146284633

Following gene: 146284635

Centisome position: 84.1

GC content: 57.91

Gene sequence:

>2523_bases
ATGACCGCCTACCGCTGGCGCATGTTCCTTCAGGTGAATAACTGGATTGGTTTCTGGATTTTCATTTTGTTCGCCGTGCT
GGCGTCCGCCATTTTCTTCTGGCGCATTCCCCAGGAAACCCTCGATAACGGCTCCCTGTGGTGGTTCGCGTGGATGAACA
GCAGTTTTATCGATCTGATGCCAGCCAGCGCCCCGAAACTCTACGACATTCACTACTGGTACGCGCCGACGCAGACGCCG
ATGGTGCTGAAAATGACCCTCGCGCAAATCTTTACCGACCCCTACATGACGGCAATGGGCGATCAGGTGCTCAGTGAGCT
GCAGTGGGCTGGCCTGGCAAGCGGCGTGTTCAGTATGGCGGTTTTTCTGGCCGTCACCTGGTACATCGTGGGGATAGGGC
GTCGTGAGAGCGAGGATGAATATCTCTCAGGTATGACGCTGACCGACAAAGCCGCCGACGTTAACCAGCTGCTGCGCCGG
AACGGGGAGTTGTCTGACCTGCGCGTGGGTGACCTGCACATGGTCAGAATGGCGGAGGTCATGAACTTCCTGATGCACGG
GACCATCGGGGTGGGTAAGTCGACCCTCATCCGCTGGCTGCTGGATTACATCCGTAAACGCGGTGACCGGGCCATTATTT
ACGACTCCGGCTGTACCTTCACCGAAACCCACTACAACCCCGATACCGACTTCATTCTTAACGCGCACGACGATCGCTGC
GCGAACTGGCAGCTGTGGGGCGAGTGCGTCGATGCCGTTGATTACGACAATATGGCGTCGAGCCTGATCCCCGTGGAAGG
TGAATCGGACCCGTTCTGGGTCTCCAGCTCGCGCACCATCTTTGCGGACCTGGCGATTCGGATGTCGGTTGACCCGGACC
GCAGTATTGAGAAATTCCTCAAAACCCTGCTGTCACTCAGCATGAAAAGCCTGCGTGAGTATCTGGCTAACACGCCGTCG
GCCAACCTGGTTGAGGAGAAAATCGAAAAGACCGCCATCTCCATCCGTTCTGTCGTCACCAACTATGCGAAGTCGCTGCG
CTACCTGCAGGGGCTGGATGATGGCGTCAAACCACCGTTCACCATCCGCGAATGGATGACAAAAGAGGAGCATGACAGCA
GCTGGCTGTTTATCTCCACTCAGGCCCGGCACCGTAAAAGCGTGCGACCGCTCATTTCCCTGTGGGTGTCACTGGCCACC
ATGATGCTGCAGAGCATGGGGGAGAACAGCGATCGTCGCGTCTGGTTCATCTACGATGAAATCCCGAGCCTGCAGCGTAT
TCCTGAGCTGGCAGAAACTCTCGCGGAAGCCCGTAAGTTTGGCGGGTGCTTTGTACTGGGCATGCAGAACATGGCGCAGC
TGGTCCACGTCTACGGCCGGGAACTGGCCAAAAGTATTTTCGACCTGATGAACACCCGTATGTACGGTCGCTCCCCGAGC
GCCGAGATGGCCAAAGTGGTGGAGGAGGAGCTGGGTAACCAGCGTAAACGCAAAATCCGGGAGCAGAACAGCTACGGTCT
GGACCAGGTGCGTGACGGTGTGTCGCTCGGCAAGGATGAGGTCAATAACCCGATAGTGGATTACGAGCAGGTGATGCGCC
TGCCCAACCTGAATTTTTACGTGCGCCTGCCGGGTGAGTATCCGGTAGTGCGCCTGAAGCTGAAATACCGTGAGCAGAAG
AAGCACCACCCTGGCCTGATAGAGCGCAATATCCACGACGCCCTGAGTCCGGAGCTGGAAAAGGTGATTCAGGCCAATGA
ACGGGCGGCCTCCGTCGCGGGCCTTGCCTTCCCGACCGGTGATGAGGTGCTGGAGAAAGGCAGTAACAGTGAAACCGCCA
CCACGATAAACACGCCGGCAACGGTCCGGCAAACGCCTGTGGTGGCAAAACCCGTGACTGCCTCGGCGATATCGCAGAAA
CCTGCGCCGGCCGTGACCGCCGTGAATAAGCCCGATGAGCCGGTTTTACCGGTTAAACACAGTCCGGTGACACCCCCTGC
CACTGAACCTGAAAAAAACAACCTGGTATCGCTTCACAGTATCCGTCAGACCGCGCCTTCCCCGGACAGTGGTCTTCCTG
TCGCAGAAACACCTTCTGAGCACGCTGTGTCTTCTGCACCCTCTGAAGCGGCAGCCTCAGTTGTCCCTTCGGTTGCATTA
CCTGCAGCCCTGCAAAGTCTGCGTAACCGCCCCGTTTCGCCTGAGCCAGCGCCGACGTCCGCCCTTGGCATGCTGCAAAA
AGCCCGTCAGCGCCCGGTCAACACGGAAAGCGATCAGCAGGGTGAGGATAATGCCGGCGGGGAATCCATGAATCTCGAGA
TGCATGTCTCTGAACGGGCAGACGGTGGCCTGAGCATCACGACGGCAGGTCACCCTCCCGAGCCTGAACACGCGGCTGAA
ACCCATCGTGTCAGCCGGCAACTGGCCCAGGAAGAAGAGAACATTTTACGTCACCGTGAGCCGGACGATCCGGGTTACAG
CGATTACGACCAACACTACGATGACAGAGAGCCAGACCTATGA

Upstream 100 bases:

>100_bases
TCCCCACTTTCTGATAACCCACATCACCTGCCGGTGATGCGATAACTGCCGGACATTTTCTATGAGCTTTGCAGGAAAAA
ATCTTACCCAGGGCGGGCAG

Downstream 100 bases:

>100_bases
TGTCAGTCGCCCCCGTAGCCTCAGCCGGCGGAGCCGCCGGCTACTACAGCAATGCCGATAACTACTATTTCCTCGGGAAT
CTCCAGAGCCTGTGGCTGGG

Product: Type IV secretory pathway VirD4 components-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 840; Mature: 839

Protein sequence:

>840_residues
MTAYRWRMFLQVNNWIGFWIFILFAVLASAIFFWRIPQETLDNGSLWWFAWMNSSFIDLMPASAPKLYDIHYWYAPTQTP
MVLKMTLAQIFTDPYMTAMGDQVLSELQWAGLASGVFSMAVFLAVTWYIVGIGRRESEDEYLSGMTLTDKAADVNQLLRR
NGELSDLRVGDLHMVRMAEVMNFLMHGTIGVGKSTLIRWLLDYIRKRGDRAIIYDSGCTFTETHYNPDTDFILNAHDDRC
ANWQLWGECVDAVDYDNMASSLIPVEGESDPFWVSSSRTIFADLAIRMSVDPDRSIEKFLKTLLSLSMKSLREYLANTPS
ANLVEEKIEKTAISIRSVVTNYAKSLRYLQGLDDGVKPPFTIREWMTKEEHDSSWLFISTQARHRKSVRPLISLWVSLAT
MMLQSMGENSDRRVWFIYDEIPSLQRIPELAETLAEARKFGGCFVLGMQNMAQLVHVYGRELAKSIFDLMNTRMYGRSPS
AEMAKVVEEELGNQRKRKIREQNSYGLDQVRDGVSLGKDEVNNPIVDYEQVMRLPNLNFYVRLPGEYPVVRLKLKYREQK
KHHPGLIERNIHDALSPELEKVIQANERAASVAGLAFPTGDEVLEKGSNSETATTINTPATVRQTPVVAKPVTASAISQK
PAPAVTAVNKPDEPVLPVKHSPVTPPATEPEKNNLVSLHSIRQTAPSPDSGLPVAETPSEHAVSSAPSEAAASVVPSVAL
PAALQSLRNRPVSPEPAPTSALGMLQKARQRPVNTESDQQGEDNAGGESMNLEMHVSERADGGLSITTAGHPPEPEHAAE
THRVSRQLAQEEENILRHREPDDPGYSDYDQHYDDREPDL

Sequences:

>Translated_840_residues
MTAYRWRMFLQVNNWIGFWIFILFAVLASAIFFWRIPQETLDNGSLWWFAWMNSSFIDLMPASAPKLYDIHYWYAPTQTP
MVLKMTLAQIFTDPYMTAMGDQVLSELQWAGLASGVFSMAVFLAVTWYIVGIGRRESEDEYLSGMTLTDKAADVNQLLRR
NGELSDLRVGDLHMVRMAEVMNFLMHGTIGVGKSTLIRWLLDYIRKRGDRAIIYDSGCTFTETHYNPDTDFILNAHDDRC
ANWQLWGECVDAVDYDNMASSLIPVEGESDPFWVSSSRTIFADLAIRMSVDPDRSIEKFLKTLLSLSMKSLREYLANTPS
ANLVEEKIEKTAISIRSVVTNYAKSLRYLQGLDDGVKPPFTIREWMTKEEHDSSWLFISTQARHRKSVRPLISLWVSLAT
MMLQSMGENSDRRVWFIYDEIPSLQRIPELAETLAEARKFGGCFVLGMQNMAQLVHVYGRELAKSIFDLMNTRMYGRSPS
AEMAKVVEEELGNQRKRKIREQNSYGLDQVRDGVSLGKDEVNNPIVDYEQVMRLPNLNFYVRLPGEYPVVRLKLKYREQK
KHHPGLIERNIHDALSPELEKVIQANERAASVAGLAFPTGDEVLEKGSNSETATTINTPATVRQTPVVAKPVTASAISQK
PAPAVTAVNKPDEPVLPVKHSPVTPPATEPEKNNLVSLHSIRQTAPSPDSGLPVAETPSEHAVSSAPSEAAASVVPSVAL
PAALQSLRNRPVSPEPAPTSALGMLQKARQRPVNTESDQQGEDNAGGESMNLEMHVSERADGGLSITTAGHPPEPEHAAE
THRVSRQLAQEEENILRHREPDDPGYSDYDQHYDDREPDL
>Mature_839_residues
TAYRWRMFLQVNNWIGFWIFILFAVLASAIFFWRIPQETLDNGSLWWFAWMNSSFIDLMPASAPKLYDIHYWYAPTQTPM
VLKMTLAQIFTDPYMTAMGDQVLSELQWAGLASGVFSMAVFLAVTWYIVGIGRRESEDEYLSGMTLTDKAADVNQLLRRN
GELSDLRVGDLHMVRMAEVMNFLMHGTIGVGKSTLIRWLLDYIRKRGDRAIIYDSGCTFTETHYNPDTDFILNAHDDRCA
NWQLWGECVDAVDYDNMASSLIPVEGESDPFWVSSSRTIFADLAIRMSVDPDRSIEKFLKTLLSLSMKSLREYLANTPSA
NLVEEKIEKTAISIRSVVTNYAKSLRYLQGLDDGVKPPFTIREWMTKEEHDSSWLFISTQARHRKSVRPLISLWVSLATM
MLQSMGENSDRRVWFIYDEIPSLQRIPELAETLAEARKFGGCFVLGMQNMAQLVHVYGRELAKSIFDLMNTRMYGRSPSA
EMAKVVEEELGNQRKRKIREQNSYGLDQVRDGVSLGKDEVNNPIVDYEQVMRLPNLNFYVRLPGEYPVVRLKLKYREQKK
HHPGLIERNIHDALSPELEKVIQANERAASVAGLAFPTGDEVLEKGSNSETATTINTPATVRQTPVVAKPVTASAISQKP
APAVTAVNKPDEPVLPVKHSPVTPPATEPEKNNLVSLHSIRQTAPSPDSGLPVAETPSEHAVSSAPSEAAASVVPSVALP
AALQSLRNRPVSPEPAPTSALGMLQKARQRPVNTESDQQGEDNAGGESMNLEMHVSERADGGLSITTAGHPPEPEHAAET
HRVSRQLAQEEENILRHREPDDPGYSDYDQHYDDREPDL

Specific function: TraD is a cell envelope protein. The function of traD is unknown but it is essential for DNA transfer. It may form or may be part of a non-specific pore for DNA export, or it may directly energize DNA transport [H]

COG id: COG3505

COG function: function code U; Type IV secretory pathway, VirD4 components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To traD of plasmid IncFII R100 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014128
- InterPro:   IPR019476
- InterPro:   IPR022585 [H]

Pfam domain/function: PF12615 TraD_N; PF10412 TrwB_AAD_bind [H]

EC number: NA

Molecular weight: Translated: 94369; Mature: 94238

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAYRWRMFLQVNNWIGFWIFILFAVLASAIFFWRIPQETLDNGSLWWFAWMNSSFIDLM
CCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEEECCCCHHHHC
PASAPKLYDIHYWYAPTQTPMVLKMTLAQIFTDPYMTAMGDQVLSELQWAGLASGVFSMA
CCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFLAVTWYIVGIGRRESEDEYLSGMTLTDKAADVNQLLRRNGELSDLRVGDLHMVRMAEV
HHHHHHHHHHCCCCCCCCHHHHCCCEECCHHHHHHHHHHCCCCCCCEEECHHHHHHHHHH
MNFLMHGTIGVGKSTLIRWLLDYIRKRGDRAIIYDSGCTFTETHYNPDTDFILNAHDDRC
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCCCCCCEEEECCCCCC
ANWQLWGECVDAVDYDNMASSLIPVEGESDPFWVSSSRTIFADLAIRMSVDPDRSIEKFL
CCHHHHHHHHHHHCHHHHHHCEECCCCCCCCEEECCCCEEEEEEEEEEECCCCHHHHHHH
KTLLSLSMKSLREYLANTPSANLVEEKIEKTAISIRSVVTNYAKSLRYLQGLDDGVKPPF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
TIREWMTKEEHDSSWLFISTQARHRKSVRPLISLWVSLATMMLQSMGENSDRRVWFIYDE
HHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
IPSLQRIPELAETLAEARKFGGCFVLGMQNMAQLVHVYGRELAKSIFDLMNTRMYGRSPS
CCCHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AEMAKVVEEELGNQRKRKIREQNSYGLDQVRDGVSLGKDEVNNPIVDYEQVMRLPNLNFY
HHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCHHHCCCCCCCHHHHHHCCCCCEE
VRLPGEYPVVRLKLKYREQKKHHPGLIERNIHDALSPELEKVIQANERAASVAGLAFPTG
EECCCCCCEEEEEEEHHHHHCCCCCCHHCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
DEVLEKGSNSETATTINTPATVRQTPVVAKPVTASAISQKPAPAVTAVNKPDEPVLPVKH
HHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCEEECCCCCCCCCCCCC
SPVTPPATEPEKNNLVSLHSIRQTAPSPDSGLPVAETPSEHAVSSAPSEAAASVVPSVAL
CCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHH
PAALQSLRNRPVSPEPAPTSALGMLQKARQRPVNTESDQQGEDNAGGESMNLEMHVSERA
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
DGGLSITTAGHPPEPEHAAETHRVSRQLAQEEENILRHREPDDPGYSDYDQHYDDREPDL
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCC
>Mature Secondary Structure 
TAYRWRMFLQVNNWIGFWIFILFAVLASAIFFWRIPQETLDNGSLWWFAWMNSSFIDLM
CCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEEECCCCHHHHC
PASAPKLYDIHYWYAPTQTPMVLKMTLAQIFTDPYMTAMGDQVLSELQWAGLASGVFSMA
CCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFLAVTWYIVGIGRRESEDEYLSGMTLTDKAADVNQLLRRNGELSDLRVGDLHMVRMAEV
HHHHHHHHHHCCCCCCCCHHHHCCCEECCHHHHHHHHHHCCCCCCCEEECHHHHHHHHHH
MNFLMHGTIGVGKSTLIRWLLDYIRKRGDRAIIYDSGCTFTETHYNPDTDFILNAHDDRC
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCCCCCCEEEECCCCCC
ANWQLWGECVDAVDYDNMASSLIPVEGESDPFWVSSSRTIFADLAIRMSVDPDRSIEKFL
CCHHHHHHHHHHHCHHHHHHCEECCCCCCCCEEECCCCEEEEEEEEEEECCCCHHHHHHH
KTLLSLSMKSLREYLANTPSANLVEEKIEKTAISIRSVVTNYAKSLRYLQGLDDGVKPPF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
TIREWMTKEEHDSSWLFISTQARHRKSVRPLISLWVSLATMMLQSMGENSDRRVWFIYDE
HHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
IPSLQRIPELAETLAEARKFGGCFVLGMQNMAQLVHVYGRELAKSIFDLMNTRMYGRSPS
CCCHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AEMAKVVEEELGNQRKRKIREQNSYGLDQVRDGVSLGKDEVNNPIVDYEQVMRLPNLNFY
HHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCHHHCCCCCCCHHHHHHCCCCCEE
VRLPGEYPVVRLKLKYREQKKHHPGLIERNIHDALSPELEKVIQANERAASVAGLAFPTG
EECCCCCCEEEEEEEHHHHHCCCCCCHHCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
DEVLEKGSNSETATTINTPATVRQTPVVAKPVTASAISQKPAPAVTAVNKPDEPVLPVKH
HHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCEEECCCCCCCCCCCCC
SPVTPPATEPEKNNLVSLHSIRQTAPSPDSGLPVAETPSEHAVSSAPSEAAASVVPSVAL
CCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHH
PAALQSLRNRPVSPEPAPTSALGMLQKARQRPVNTESDQQGEDNAGGESMNLEMHVSERA
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
DGGLSITTAGHPPEPEHAAETHRVSRQLAQEEENILRHREPDDPGYSDYDQHYDDREPDL
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2680768; 7915817; 10464182; 3323526; 2164585; 2163400; 1618779; 10498725 [H]