Click here to switch to the map view.

The map label for this gene is namA [H]

Identifier: 146284546

GI number: 146284546

Start: 30258

End: 31352

Strand: Direct

Name: namA [H]

Synonym: Ent638_4220

Alternate gene names: 146284546

Gene position: 30258-31352 (Clockwise)

Preceding gene: 146284544

Following gene: 146284547

Centisome position: 19.18

GC content: 53.33

Gene sequence:

>1095_bases
ATGACAGGTTTATTTTCTTCTTTTTCGCTGAAAGATATTACGCTACGTAATCGGATCGCAGTTTCTCCCATGTGTCAGTA
CCAGGCTGTCGATGGCTTTATCAATGACTGGCACAGTGCCCATTATTCCATGCTCGCACGTGGAGGTGCTGGCCTCGTTG
TCGTTGAAGCCACTGCCGTAGCACCTGAGGGCCGAATTACGCCAGGTGATGTCGGATTATGGAGTGATGAACACACCGCA
GGGTTGTCGTCCATTGCCGCAGCAATAAAGACAGCCGGGGCTGTCGCAGGGATTCAGCTTGCTCATGCGGGCCGTAAAGC
CGGCTGTACGCCACCATGGCAGGGTGGCGCACCTCTGGATCGAGATGATGCACTGGCGTGGGAGCCTGTCGGGCCTTCCG
CCGTCCCCTTCGTACCCGGAAATGACTATATTCCCCGTGAAATGACCAAAGATAATATCCGACAAACGCAGCAGGACTTT
GCCCGTGCGGCAGAGCGTGCCTGTCAGGCGGGTTTCCAGTGGCTGGAACTGCATTTTGCCCATGGTTTCCTGGCACAAAG
TTTTCTTTCCCCACAGTCAAATACCCGTTCGGATGAATATGGTGGTTCTCTTGAAGGGCGTGCCCGCTTCTTACTGGAGA
CAGTGGCTGAAGTCCGCAAGTTCTGGCCTGATAATTTCCCCTTAACGGTACGCCTCGGCGTGGTGGAATTTGATGACTGT
CCTGAACATTCTTTCAGCGAATCACTCAAGGTAATCGGCTGGCTGAAGGATGCCGGTGTTGATTTTGTTGATGTGGGTCT
TTCTCTGGCAACGCCAGGCGAGAACATCCCGTGGGCGGCAAACTTTATGGTTCCATGGGCCGCACGTGTTCGCCGGGAGA
AAAACATTCCTGTCGGGACAAGCTGGATGATTACTCAGGCTAAAGAAGCGAATGAATTCATACAGGACGGTAAAGTTGAC
GTGATCTTTTTCGCCCGTACATTGCTGGCTAATCCGCACTGGCCATATCGCGCGGCGCGGGAGCTTGAAATCACCGACCC
GCACGCTGTATTACCCACACCCTATGCATACTGGTTACAAAACTGGTCCGAATGA

Upstream 100 bases:

>100_bases
ATAAATCATTTCAGGCAATGATTGTGGTGAAGTGAGCAAGCCATCTTCATGCTTTGTGGTCAATAATACTTCTATCATGT
TTCTGCTTATGGAGTGCCTT

Downstream 100 bases:

>100_bases
CCATAACAGGTTGCGTCGTCCCGGCCACGTAACCGGCCCTCACCAGGGGTACCCGTCCTGATAGTAAAACCTTTATTAAG
CGGAGAACGATATGAGTCAG

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MTGLFSSFSLKDITLRNRIAVSPMCQYQAVDGFINDWHSAHYSMLARGGAGLVVVEATAVAPEGRITPGDVGLWSDEHTA
GLSSIAAAIKTAGAVAGIQLAHAGRKAGCTPPWQGGAPLDRDDALAWEPVGPSAVPFVPGNDYIPREMTKDNIRQTQQDF
ARAAERACQAGFQWLELHFAHGFLAQSFLSPQSNTRSDEYGGSLEGRARFLLETVAEVRKFWPDNFPLTVRLGVVEFDDC
PEHSFSESLKVIGWLKDAGVDFVDVGLSLATPGENIPWAANFMVPWAARVRREKNIPVGTSWMITQAKEANEFIQDGKVD
VIFFARTLLANPHWPYRAARELEITDPHAVLPTPYAYWLQNWSE

Sequences:

>Translated_364_residues
MTGLFSSFSLKDITLRNRIAVSPMCQYQAVDGFINDWHSAHYSMLARGGAGLVVVEATAVAPEGRITPGDVGLWSDEHTA
GLSSIAAAIKTAGAVAGIQLAHAGRKAGCTPPWQGGAPLDRDDALAWEPVGPSAVPFVPGNDYIPREMTKDNIRQTQQDF
ARAAERACQAGFQWLELHFAHGFLAQSFLSPQSNTRSDEYGGSLEGRARFLLETVAEVRKFWPDNFPLTVRLGVVEFDDC
PEHSFSESLKVIGWLKDAGVDFVDVGLSLATPGENIPWAANFMVPWAARVRREKNIPVGTSWMITQAKEANEFIQDGKVD
VIFFARTLLANPHWPYRAARELEITDPHAVLPTPYAYWLQNWSE
>Mature_363_residues
TGLFSSFSLKDITLRNRIAVSPMCQYQAVDGFINDWHSAHYSMLARGGAGLVVVEATAVAPEGRITPGDVGLWSDEHTAG
LSSIAAAIKTAGAVAGIQLAHAGRKAGCTPPWQGGAPLDRDDALAWEPVGPSAVPFVPGNDYIPREMTKDNIRQTQQDFA
RAAERACQAGFQWLELHFAHGFLAQSFLSPQSNTRSDEYGGSLEGRARFLLETVAEVRKFWPDNFPLTVRLGVVEFDDCP
EHSFSESLKVIGWLKDAGVDFVDVGLSLATPGENIPWAANFMVPWAARVRREKNIPVGTSWMITQAKEANEFIQDGKVDV
IFFARTLLANPHWPYRAARELEITDPHAVLPTPYAYWLQNWSE

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=362, Percent_Identity=29.0055248618785, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1789463, Length=348, Percent_Identity=25.2873563218391, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17566914, Length=264, Percent_Identity=31.0606060606061, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17540738, Length=270, Percent_Identity=28.8888888888889, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17565138, Length=315, Percent_Identity=25.7142857142857, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17559802, Length=315, Percent_Identity=26.984126984127, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17559804, Length=233, Percent_Identity=30.0429184549356, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI72001454, Length=265, Percent_Identity=28.6792452830189, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17564188, Length=232, Percent_Identity=28.8793103448276, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325086, Length=223, Percent_Identity=29.1479820627803, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321973, Length=226, Percent_Identity=29.2035398230088, Blast_Score=93, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40053; Mature: 39922

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLFSSFSLKDITLRNRIAVSPMCQYQAVDGFINDWHSAHYSMLARGGAGLVVVEATAV
CCCCCCCCCCEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEE
APEGRITPGDVGLWSDEHTAGLSSIAAAIKTAGAVAGIQLAHAGRKAGCTPPWQGGAPLD
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
RDDALAWEPVGPSAVPFVPGNDYIPREMTKDNIRQTQQDFARAAERACQAGFQWLELHFA
CCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
HGFLAQSFLSPQSNTRSDEYGGSLEGRARFLLETVAEVRKFWPDNFPLTVRLGVVEFDDC
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
PEHSFSESLKVIGWLKDAGVDFVDVGLSLATPGENIPWAANFMVPWAARVRREKNIPVGT
CCHHHHHHHHHHEEHHHCCCCEEECCEEEECCCCCCCEEECCCCHHHHHHHHCCCCCCCC
SWMITQAKEANEFIQDGKVDVIFFARTLLANPHWPYRAARELEITDPHAVLPTPYAYWLQ
CEEEECHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHH
NWSE
CCCC
>Mature Secondary Structure 
TGLFSSFSLKDITLRNRIAVSPMCQYQAVDGFINDWHSAHYSMLARGGAGLVVVEATAV
CCCCCCCCCEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEE
APEGRITPGDVGLWSDEHTAGLSSIAAAIKTAGAVAGIQLAHAGRKAGCTPPWQGGAPLD
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
RDDALAWEPVGPSAVPFVPGNDYIPREMTKDNIRQTQQDFARAAERACQAGFQWLELHFA
CCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
HGFLAQSFLSPQSNTRSDEYGGSLEGRARFLLETVAEVRKFWPDNFPLTVRLGVVEFDDC
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
PEHSFSESLKVIGWLKDAGVDFVDVGLSLATPGENIPWAANFMVPWAARVRREKNIPVGT
CCHHHHHHHHHHEEHHHCCCCEEECCEEEECCCCCCCEEECCCCHHHHHHHHCCCCCCCC
SWMITQAKEANEFIQDGKVDVIFFARTLLANPHWPYRAARELEITDPHAVLPTPYAYWLQ
CEEEECHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHH
NWSE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA