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The map label for this gene is desR [H]

Identifier: 146284530

GI number: 146284530

Start: 8519

End: 9127

Strand: Reverse

Name: desR [H]

Synonym: Ent638_4204

Alternate gene names: 146284530

Gene position: 9127-8519 (Counterclockwise)

Preceding gene: 146284535

Following gene: 146284529

Centisome position: 5.79

GC content: 44.99

Gene sequence:

>609_bases
ATGACAATCATTATCGCAGATGACCATCCATTGTTCAGAGATGCGATGGCGAAAAAACTCGCACAACAGAATGATCCCGA
TATCATAGAAGCAGGTAGTTTTTCTGAGCTGGAGTCGGTTCTCGAAACCTTCCCGGCTCCTGACATTTTAATTCTTGATC
TGCAATTTCCTGGGCTGGATTCACTTTCAAAACTGGTCACACTGAAAAACAAACTCAAAAGAACCGCGTTGATTATTGTT
TCAATGAATACGGATGCCGCCCTTGTTCAGGCAGTCATGGCCACCGGGGTTGACGGATACATCAGCAAAAATGTTCCTCC
TGAACAACTACTGAGCGATATTGCTGACATTCAGAACGGAAACATTGTGGTTAATTATATACCGGGGACCCTTCCCAACC
TGCGGGTGACGCCAGCAGAACTGGACTTGTTGACAGAACGGCAGAGAGAGGTTCTACAGTTACTGGTGCAAGGAAAATCG
AATAAACAAATTGCGCAATCGCTCAACATATCACCGTTTACAGTACGCATCCATGTTTCGCAGGTTCTTCATGTACTAGG
TGTGCCAACTCGAACAGTCGCAATTGCGCAATATTCACATCTTATCTGA

Upstream 100 bases:

>100_bases
TCGATTTAACCCATTAGATCTATAGGGGTTTCAACAGGTGACTGGTTAAGTTTAAAGTCATCAGCCATACTTAAACGATA
GAATTTTTGAGGTTGACTTT

Downstream 100 bases:

>100_bases
ATTGACCTGATAGATCGGCTCCCGCTCGGGAATCACCGTAAACTCCATCCTCACTGGTGAAGGCAATGCCATTTAGAGAA
TATGAAATTCAAAGCCAGCA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MTIIIADDHPLFRDAMAKKLAQQNDPDIIEAGSFSELESVLETFPAPDILILDLQFPGLDSLSKLVTLKNKLKRTALIIV
SMNTDAALVQAVMATGVDGYISKNVPPEQLLSDIADIQNGNIVVNYIPGTLPNLRVTPAELDLLTERQREVLQLLVQGKS
NKQIAQSLNISPFTVRIHVSQVLHVLGVPTRTVAIAQYSHLI

Sequences:

>Translated_202_residues
MTIIIADDHPLFRDAMAKKLAQQNDPDIIEAGSFSELESVLETFPAPDILILDLQFPGLDSLSKLVTLKNKLKRTALIIV
SMNTDAALVQAVMATGVDGYISKNVPPEQLLSDIADIQNGNIVVNYIPGTLPNLRVTPAELDLLTERQREVLQLLVQGKS
NKQIAQSLNISPFTVRIHVSQVLHVLGVPTRTVAIAQYSHLI
>Mature_201_residues
TIIIADDHPLFRDAMAKKLAQQNDPDIIEAGSFSELESVLETFPAPDILILDLQFPGLDSLSKLVTLKNKLKRTALIIVS
MNTDAALVQAVMATGVDGYISKNVPPEQLLSDIADIQNGNIVVNYIPGTLPNLRVTPAELDLLTERQREVLQLLVQGKSN
KQIAQSLNISPFTVRIHVSQVLHVLGVPTRTVAIAQYSHLI

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=200, Percent_Identity=34, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790102, Length=192, Percent_Identity=28.125, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1787473, Length=186, Percent_Identity=32.258064516129, Blast_Score=78, Evalue=3e-16,
Organism=Escherichia coli, GI1788712, Length=198, Percent_Identity=29.2929292929293, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1788546, Length=208, Percent_Identity=27.8846153846154, Blast_Score=67, Evalue=6e-13,
Organism=Escherichia coli, GI1788222, Length=180, Percent_Identity=22.7777777777778, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1786747, Length=206, Percent_Identity=24.7572815533981, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22107; Mature: 21976

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIIIADDHPLFRDAMAKKLAQQNDPDIIEAGSFSELESVLETFPAPDILILDLQFPGLD
CEEEEECCCCHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHCCCCCEEEEEECCCCHH
SLSKLVTLKNKLKRTALIIVSMNTDAALVQAVMATGVDGYISKNVPPEQLLSDIADIQNG
HHHHHHHHHHHHCEEEEEEEEECCCHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHCCCC
NIVVNYIPGTLPNLRVTPAELDLLTERQREVLQLLVQGKSNKQIAQSLNISPFTVRIHVS
CEEEEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEEHH
QVLHVLGVPTRTVAIAQYSHLI
HHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TIIIADDHPLFRDAMAKKLAQQNDPDIIEAGSFSELESVLETFPAPDILILDLQFPGLD
EEEEECCCCHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHCCCCCEEEEEECCCCHH
SLSKLVTLKNKLKRTALIIVSMNTDAALVQAVMATGVDGYISKNVPPEQLLSDIADIQNG
HHHHHHHHHHHHCEEEEEEEEECCCHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHCCCC
NIVVNYIPGTLPNLRVTPAELDLLTERQREVLQLLVQGKSNKQIAQSLNISPFTVRIHVS
CEEEEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEEHH
QVLHVLGVPTRTVAIAQYSHLI
HHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]