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The map label for this gene is ycaN [C]

Identifier: 145300039

GI number: 145300039

Start: 3394078

End: 3394986

Strand: Direct

Name: ycaN [C]

Synonym: ASA_3138

Alternate gene names: 145300039

Gene position: 3394078-3394986 (Clockwise)

Preceding gene: 145300036

Following gene: 145300040

Centisome position: 72.18

GC content: 60.18

Gene sequence:

>909_bases
ATGGTCATCACCCGTACCGATCTCGCCGAACTGGCGGTTTTTGCCGCCGTGGCCCGCCATCAGAGTTTCAGCAAGGCCGC
TCTCGAACTCGGCGTCTCGGCCTCCGCCCTGAGCCACAGCCTGAAAGGGCTGGAGACCCGGCTCGGTGTCAGACTGCTCA
ATCGCAGCACACGCGCCGTGGTGCCGACCGATGTGGGTCAACGTCTGCTCGAGCAGTTGCTGCCGACCCTAAATACCCTG
GAAGAGGCCCTCGACGAGCTGGCCCATCACAGCAATGAGCCTGTCGGGCGACTGAAAATAAGCGCACCAAGGGAGGCCAT
CAACGACTTGCTGGCCCCTGTGCTTATCGATTACATGGTGCGCTACCCGCGCATGCAGGTAGAGGTGGTGGAGCAGGAGC
TGATGCCACGGCTTATCGAGGATGGCTATGACGCCGCCATCTTCTACGGTGATCTGCTGCCCAAGGAGATGATCGGTGTG
CCACTGGGACCACACCAGCGTTATCTGGTAGTGGGCTCACCGGCCTATCTGAGCAAACACGGCACACCGCAACATCCCCG
CGAGCTGTCGCGTCACGCCTGCATAGGTTATCGGTTGACACCTTCCCACCATTATCGCTGGGCGTTTACCGAGGGAAAGG
GGAGCATGCTGGAAATCGAGGTGACTGGGCCGCTCACCACCAGCACGCCAGCCCTCTATCTTGGCGCTGCCGAGGCAGGG
CTGGGATTGGCTTACTGTCCGGAAGAGGAGGTCAGCAAGCAGCTGGCAGAAGGGAAACTGTTGCGAGTGCTGGAGCCCTG
GTGCCCAACCTTCGTGGGATTTTCACTCTTTTATCCAAGCCGTCATCAACTGGGTAAAGGTCTGCGCGCCCTGATCGACA
TGCTCAAGGCGCACTACCAAATCCGGTGA

Upstream 100 bases:

>100_bases
GGTATAACAAACCGCTTACAGTTGGTCATTTATTGGCCAGGTTGTGCCTCGCCTTGCCCTGACGTACCCTGTTGTTCACC
CTTTTTTTCCCTGAGTTGTC

Downstream 100 bases:

>100_bases
TTACTGAATTTTACTCATCAATTCATCAATCTTAAGGCGGATTATCAACAAAAATGTATTAATTTAGACTGTCGGCTCGA
TAATCGAACTCCCCAAGAGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MVITRTDLAELAVFAAVARHQSFSKAALELGVSASALSHSLKGLETRLGVRLLNRSTRAVVPTDVGQRLLEQLLPTLNTL
EEALDELAHHSNEPVGRLKISAPREAINDLLAPVLIDYMVRYPRMQVEVVEQELMPRLIEDGYDAAIFYGDLLPKEMIGV
PLGPHQRYLVVGSPAYLSKHGTPQHPRELSRHACIGYRLTPSHHYRWAFTEGKGSMLEIEVTGPLTTSTPALYLGAAEAG
LGLAYCPEEEVSKQLAEGKLLRVLEPWCPTFVGFSLFYPSRHQLGKGLRALIDMLKAHYQIR

Sequences:

>Translated_302_residues
MVITRTDLAELAVFAAVARHQSFSKAALELGVSASALSHSLKGLETRLGVRLLNRSTRAVVPTDVGQRLLEQLLPTLNTL
EEALDELAHHSNEPVGRLKISAPREAINDLLAPVLIDYMVRYPRMQVEVVEQELMPRLIEDGYDAAIFYGDLLPKEMIGV
PLGPHQRYLVVGSPAYLSKHGTPQHPRELSRHACIGYRLTPSHHYRWAFTEGKGSMLEIEVTGPLTTSTPALYLGAAEAG
LGLAYCPEEEVSKQLAEGKLLRVLEPWCPTFVGFSLFYPSRHQLGKGLRALIDMLKAHYQIR
>Mature_302_residues
MVITRTDLAELAVFAAVARHQSFSKAALELGVSASALSHSLKGLETRLGVRLLNRSTRAVVPTDVGQRLLEQLLPTLNTL
EEALDELAHHSNEPVGRLKISAPREAINDLLAPVLIDYMVRYPRMQVEVVEQELMPRLIEDGYDAAIFYGDLLPKEMIGV
PLGPHQRYLVVGSPAYLSKHGTPQHPRELSRHACIGYRLTPSHHYRWAFTEGKGSMLEIEVTGPLTTSTPALYLGAAEAG
LGLAYCPEEEVSKQLAEGKLLRVLEPWCPTFVGFSLFYPSRHQLGKGLRALIDMLKAHYQIR

Specific function: May have a role in the regulation of oprD expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=36.3013698630137, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1787589, Length=295, Percent_Identity=33.5593220338983, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=30.8219178082192, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1789639, Length=253, Percent_Identity=30.0395256916996, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789440, Length=296, Percent_Identity=29.3918918918919, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=28.956228956229, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=29.6928327645051, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1788706, Length=264, Percent_Identity=27.6515151515151, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789173, Length=289, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788748, Length=119, Percent_Identity=38.655462184874, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786448, Length=299, Percent_Identity=26.4214046822742, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790011, Length=308, Percent_Identity=23.3766233766234, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI157672245, Length=173, Percent_Identity=30.0578034682081, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33490; Mature: 33490

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVITRTDLAELAVFAAVARHQSFSKAALELGVSASALSHSLKGLETRLGVRLLNRSTRAV
CEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
VPTDVGQRLLEQLLPTLNTLEEALDELAHHSNEPVGRLKISAPREAINDLLAPVLIDYMV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
RYPRMQVEVVEQELMPRLIEDGYDAAIFYGDLLPKEMIGVPLGPHQRYLVVGSPAYLSKH
HCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCHHHHCCCCCCCCCEEEEECCHHHHCC
GTPQHPRELSRHACIGYRLTPSHHYRWAFTEGKGSMLEIEVTGPLTTSTPALYLGAAEAG
CCCCCHHHHHHHHHCCEEECCCCCEEEEEECCCCCEEEEEECCCCCCCCCEEEEECHHHC
LGLAYCPEEEVSKQLAEGKLLRVLEPWCPTFVGFSLFYPSRHQLGKGLRALIDMLKAHYQ
CCEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
IR
CC
>Mature Secondary Structure
MVITRTDLAELAVFAAVARHQSFSKAALELGVSASALSHSLKGLETRLGVRLLNRSTRAV
CEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
VPTDVGQRLLEQLLPTLNTLEEALDELAHHSNEPVGRLKISAPREAINDLLAPVLIDYMV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
RYPRMQVEVVEQELMPRLIEDGYDAAIFYGDLLPKEMIGVPLGPHQRYLVVGSPAYLSKH
HCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCHHHHCCCCCCCCCEEEEECCHHHHCC
GTPQHPRELSRHACIGYRLTPSHHYRWAFTEGKGSMLEIEVTGPLTTSTPALYLGAAEAG
CCCCCHHHHHHHHHCCEEECCCCCEEEEEECCCCCEEEEEECCCCCCCCCEEEEECHHHC
LGLAYCPEEEVSKQLAEGKLLRVLEPWCPTFVGFSLFYPSRHQLGKGLRALIDMLKAHYQ
CCEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
IR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 1427017 [H]