Definition Aeromonas salmonicida subsp. salmonicida A449, complete genome.
Accession NC_009348
Length 4,702,402

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The map label for this gene is yciK [H]

Identifier: 145300015

GI number: 145300015

Start: 3363595

End: 3364350

Strand: Direct

Name: yciK [H]

Synonym: ASA_3114

Alternate gene names: 145300015

Gene position: 3363595-3364350 (Clockwise)

Preceding gene: 145300013

Following gene: 145300016

Centisome position: 71.53

GC content: 60.98

Gene sequence:

>756_bases
ATGCTCGATTATCAGGCACCCCGGGATCTGCTCAAGGACAAGGTCATTCTGGTCACAGGTGCCGGTGACGGCATAGGCCG
CGAAGCGGCGATCACCTATGCAGCCCACGGCGCGACCGTGATCCTGCTCGGCCGCACCAGTGCCAAACTCGAGGCTGTTT
ATGACCAGATTGAGGCCGCCGGTTATCCACTTCCCGCCATAGTTCCGGTGGACCTGAAAGGAGCAACCGCCGCTCACTAT
CGCGGCATGGCCGAGACCTTCGCCCAGCAGTTTGGTCGCCTCGACGGCGTGCTGTTCAACGCGGGCCTGCTCGGCACCCT
TTCTCCCTTCGAACATATTCAGGAGAAAGAGTGGGACGAGGTGATGCAGGTCAACGTGAAATCTGAATTCCTGCTGACCC
AGGCGCTGCTGCCGCTGATCCGCCAGACAGCCAAGGAGCATGGTGATGCCTCCATTGTCTACACCTCCTCCAGCGTGGGG
CGCAAAGGCCGCGCCTACTGGGGCACCTACGCTATCTCCAAGTTCGCCATCGAAGGCATGATGGAAGTGCTGGCCGACGA
ACTGGAAAACACGGCTGTGCGAGTCAACACCCTCAACCCGGGCGGTACCCGCACCAAGATGCGCGCCAGCGCCTTCCCGG
CGGAAGATCCCCAGCAGCTAAAGACGCCGGCCGACCTGATGCCGCTCTATCTCTACCTGATGGGACAGGACAGCCGTGGC
AAAACCGGTCAGACCTTTGTGGCCCAGCCCAAATAA

Upstream 100 bases:

>100_bases
ATTTTTGCCGTCTCATACTGGTCAAATGCCGTGCGGGATCAGTACACTTGCCCCTCTATTGCCGCGCGCATCTGCCACGA
ATTTGTTAACAGGAGTTGTC

Downstream 100 bases:

>100_bases
ATCAACAAAATAACCGGAACCCTGCACCGCATGGGGTTAAATTCAATAGGGTGTCGTCGGCACCCTGTCGAAGGCCTTTA
TCAGATCCGATCCCTTATCA

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLDYQAPRDLLKDKVILVTGAGDGIGREAAITYAAHGATVILLGRTSAKLEAVYDQIEAAGYPLPAIVPVDLKGATAAHY
RGMAETFAQQFGRLDGVLFNAGLLGTLSPFEHIQEKEWDEVMQVNVKSEFLLTQALLPLIRQTAKEHGDASIVYTSSSVG
RKGRAYWGTYAISKFAIEGMMEVLADELENTAVRVNTLNPGGTRTKMRASAFPAEDPQQLKTPADLMPLYLYLMGQDSRG
KTGQTFVAQPK

Sequences:

>Translated_251_residues
MLDYQAPRDLLKDKVILVTGAGDGIGREAAITYAAHGATVILLGRTSAKLEAVYDQIEAAGYPLPAIVPVDLKGATAAHY
RGMAETFAQQFGRLDGVLFNAGLLGTLSPFEHIQEKEWDEVMQVNVKSEFLLTQALLPLIRQTAKEHGDASIVYTSSSVG
RKGRAYWGTYAISKFAIEGMMEVLADELENTAVRVNTLNPGGTRTKMRASAFPAEDPQQLKTPADLMPLYLYLMGQDSRG
KTGQTFVAQPK
>Mature_251_residues
MLDYQAPRDLLKDKVILVTGAGDGIGREAAITYAAHGATVILLGRTSAKLEAVYDQIEAAGYPLPAIVPVDLKGATAAHY
RGMAETFAQQFGRLDGVLFNAGLLGTLSPFEHIQEKEWDEVMQVNVKSEFLLTQALLPLIRQTAKEHGDASIVYTSSSVG
RKGRAYWGTYAISKFAIEGMMEVLADELENTAVRVNTLNPGGTRTKMRASAFPAEDPQQLKTPADLMPLYLYLMGQDSRG
KTGQTFVAQPK

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=245, Percent_Identity=28.1632653061224, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=27.2, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI15277342, Length=261, Percent_Identity=28.735632183908, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI20149619, Length=225, Percent_Identity=29.3333333333333, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI32455239, Length=216, Percent_Identity=31.4814814814815, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5031765, Length=216, Percent_Identity=31.4814814814815, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=27.2, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI157739938, Length=204, Percent_Identity=27.4509803921569, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5031737, Length=198, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI10190704, Length=193, Percent_Identity=25.9067357512953, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI126723191, Length=192, Percent_Identity=28.125, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI19923817, Length=207, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787526, Length=250, Percent_Identity=59.2, Blast_Score=275, Evalue=3e-75,
Organism=Escherichia coli, GI1789378, Length=240, Percent_Identity=30.8333333333333, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI87082100, Length=217, Percent_Identity=33.1797235023041, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787335, Length=197, Percent_Identity=30.4568527918782, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786701, Length=210, Percent_Identity=27.6190476190476, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789208, Length=194, Percent_Identity=28.3505154639175, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786812, Length=208, Percent_Identity=26.4423076923077, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790717, Length=198, Percent_Identity=28.2828282828283, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=25, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=207, Percent_Identity=33.8164251207729, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17568967, Length=251, Percent_Identity=31.4741035856574, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=249, Percent_Identity=30.5220883534137, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=193, Percent_Identity=33.160621761658, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=28.4552845528455, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=203, Percent_Identity=29.064039408867, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=201, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=210, Percent_Identity=31.9047619047619, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=227, Percent_Identity=27.7533039647577, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=227, Percent_Identity=32.5991189427313, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=208, Percent_Identity=31.25, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=25.9109311740891, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=215, Percent_Identity=27.4418604651163, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=198, Percent_Identity=30.8080808080808, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=199, Percent_Identity=31.6582914572864, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=190, Percent_Identity=31.5789473684211, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=201, Percent_Identity=32.3383084577114, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71997402, Length=196, Percent_Identity=29.0816326530612, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115534660, Length=241, Percent_Identity=27.8008298755187, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=221, Percent_Identity=27.1493212669683, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=198, Percent_Identity=29.2929292929293, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=231, Percent_Identity=28.1385281385281, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=220, Percent_Identity=26.8181818181818, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=245, Percent_Identity=29.3877551020408, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319635, Length=216, Percent_Identity=28.7037037037037, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=222, Percent_Identity=30.1801801801802, Blast_Score=79, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6322227, Length=222, Percent_Identity=28.3783783783784, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=28.8537549407115, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28571526, Length=194, Percent_Identity=37.6288659793814, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI23397609, Length=198, Percent_Identity=33.8383838383838, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644339, Length=198, Percent_Identity=34.8484848484849, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24643142, Length=235, Percent_Identity=33.1914893617021, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21357041, Length=200, Percent_Identity=33.5, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24639444, Length=200, Percent_Identity=31, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI18859837, Length=230, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281364892, Length=221, Percent_Identity=28.9592760180996, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640492, Length=198, Percent_Identity=29.7979797979798, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21358495, Length=215, Percent_Identity=28.3720930232558, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21357673, Length=252, Percent_Identity=24.2063492063492, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27266; Mature: 27266

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MLDYQAPRDLLKDKVILVTGAGDGIGREAAITYAAHGATVILLGRTSAKLEAVYDQIEAA
CCCCCCCHHHHCCCEEEEEECCCCCCCHHEEEEEECCEEEEEEECCCHHHHHHHHHHHHC
GYPLPAIVPVDLKGATAAHYRGMAETFAQQFGRLDGVLFNAGLLGTLSPFEHIQEKEWDE
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHCCHHH
VMQVNVKSEFLLTQALLPLIRQTAKEHGDASIVYTSSSVGRKGRAYWGTYAISKFAIEGM
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHHH
MEVLADELENTAVRVNTLNPGGTRTKMRASAFPAEDPQQLKTPADLMPLYLYLMGQDSRG
HHHHHHHHCCCEEEEEECCCCCCCCEEECCCCCCCCHHHHCCCHHHHHHHHHEECCCCCC
KTGQTFVAQPK
CCCCEEEECCC
>Mature Secondary Structure
MLDYQAPRDLLKDKVILVTGAGDGIGREAAITYAAHGATVILLGRTSAKLEAVYDQIEAA
CCCCCCCHHHHCCCEEEEEECCCCCCCHHEEEEEECCEEEEEEECCCHHHHHHHHHHHHC
GYPLPAIVPVDLKGATAAHYRGMAETFAQQFGRLDGVLFNAGLLGTLSPFEHIQEKEWDE
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHCCHHH
VMQVNVKSEFLLTQALLPLIRQTAKEHGDASIVYTSSSVGRKGRAYWGTYAISKFAIEGM
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHHH
MEVLADELENTAVRVNTLNPGGTRTKMRASAFPAEDPQQLKTPADLMPLYLYLMGQDSRG
HHHHHHHHCCCEEEEEECCCCCCCCEEECCCCCCCCHHHHCCCHHHHHHHHHEECCCCCC
KTGQTFVAQPK
CCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]