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The map label for this gene is appC [H]

Identifier: 145300003

GI number: 145300003

Start: 3347594

End: 3348502

Strand: Direct

Name: appC [H]

Synonym: ASA_3102

Alternate gene names: 145300003

Gene position: 3347594-3348502 (Clockwise)

Preceding gene: 145300002

Following gene: 145300004

Centisome position: 71.19

GC content: 63.04

Gene sequence:

>909_bases
ATGCGTATGCCGACTATTTTGAAAATCCTGCTGGGCAACAAGAAAGCCGCCTTCGGCCTCTTCATCGTGGTCAGCTTCGT
GCTGATGGCACTGTTCGCCCCCCTGCTGGCCAGCAACGAACCGACCAAGCGAGTCTCCCGTCCGCACCAGCCCCCCAGCG
CCGAGTACGTGATGGGCACCACCCGCATGGGCCACGACATCTGGTCCCAATTTGCCAACGGCGCCCGCATCTCCCTGATG
GTAGGCTTCGGGGCCGGCATACTGGTGTGCGCCCTCGCCATCACCATCGGCATCACCGCCGGCTACTTTGGCGGCGTGAT
CGACGAGTGCCTCACCTTCCTGATGAACGTGGTGCTGGTGATCCCCAACCTCCCCCTGCTACTGGTGCTCGCAAGCTTTA
TCGGGGAGGCGTCACCGACGGTGATTGCGCTCATCATAGGCTTTACCTCCTGGGCCTATGGCGCGCGCGTCATCCGGGCC
CAGACCCTGGCGCTGCGCGAGAAAGAGTTCGTCATCGCCGCCGAGGTGCTGGGGGAGCCGGCCTGGCGCATCATTCTGGT
GGAGATACTGCCGAACCTCATCTCCATCATAGGGGTGAGCTTCATCGGCTCCATCATCTACGCCATCGTCACCGAGGCGA
CCCTGGAGTTCCTGGGGCTTGGCGATCCGACCGTGGTCAGCTGGGGCATCATGCTCTACAACGCCCAGACCTCCAGCGCC
ATCCTGGTGGGTGCCTGGTGGGAGATCCTGGCCCCCTGCTTCGCCATCGCCACCCTGGGCGCAGGTCTGGCCCTGCTCAA
CTTCGCCATCGACGAGATAGCCAACCCTCAGCTGCGATCCCATAAAGGGCTCAACCGCTGGAAAAAACTCGCCGCGCCCG
TCGCAGCACCACAGGAGAGGACAGCATGA

Upstream 100 bases:

>100_bases
CAGCTGCTCATCATGACCATCACCATGCTCAGCTTCAACTTCCTGGCCGACGTGCTCTACGTCTTCCTGGATCCCCGTCT
GCGTACAGGAGGCAAATAAG

Downstream 100 bases:

>100_bases
AGACCCCACCCCTGCTGTCGGTACGCAACCTCTGCGTCGACTACATCACCGAGAGCGGCGACGTGCGCGCCGTCAACTCG
GTCAGCTTTGACATAGCCCC

Product: ABC-type oligopeptide transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MRMPTILKILLGNKKAAFGLFIVVSFVLMALFAPLLASNEPTKRVSRPHQPPSAEYVMGTTRMGHDIWSQFANGARISLM
VGFGAGILVCALAITIGITAGYFGGVIDECLTFLMNVVLVIPNLPLLLVLASFIGEASPTVIALIIGFTSWAYGARVIRA
QTLALREKEFVIAAEVLGEPAWRIILVEILPNLISIIGVSFIGSIIYAIVTEATLEFLGLGDPTVVSWGIMLYNAQTSSA
ILVGAWWEILAPCFAIATLGAGLALLNFAIDEIANPQLRSHKGLNRWKKLAAPVAAPQERTA

Sequences:

>Translated_302_residues
MRMPTILKILLGNKKAAFGLFIVVSFVLMALFAPLLASNEPTKRVSRPHQPPSAEYVMGTTRMGHDIWSQFANGARISLM
VGFGAGILVCALAITIGITAGYFGGVIDECLTFLMNVVLVIPNLPLLLVLASFIGEASPTVIALIIGFTSWAYGARVIRA
QTLALREKEFVIAAEVLGEPAWRIILVEILPNLISIIGVSFIGSIIYAIVTEATLEFLGLGDPTVVSWGIMLYNAQTSSA
ILVGAWWEILAPCFAIATLGAGLALLNFAIDEIANPQLRSHKGLNRWKKLAAPVAAPQERTA
>Mature_302_residues
MRMPTILKILLGNKKAAFGLFIVVSFVLMALFAPLLASNEPTKRVSRPHQPPSAEYVMGTTRMGHDIWSQFANGARISLM
VGFGAGILVCALAITIGITAGYFGGVIDECLTFLMNVVLVIPNLPLLLVLASFIGEASPTVIALIIGFTSWAYGARVIRA
QTLALREKEFVIAAEVLGEPAWRIILVEILPNLISIIGVSFIGSIIYAIVTEATLEFLGLGDPTVVSWGIMLYNAQTSSA
ILVGAWWEILAPCFAIATLGAGLALLNFAIDEIANPQLRSHKGLNRWKKLAAPVAAPQERTA

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=263, Percent_Identity=30.7984790874525, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787054, Length=222, Percent_Identity=30.1801801801802, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787498, Length=256, Percent_Identity=30.078125, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789964, Length=276, Percent_Identity=29.7101449275362, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789889, Length=187, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788505, Length=189, Percent_Identity=29.1005291005291, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32384; Mature: 32384

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMPTILKILLGNKKAAFGLFIVVSFVLMALFAPLLASNEPTKRVSRPHQPPSAEYVMGT
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCEEECC
TRMGHDIWSQFANGARISLMVGFGAGILVCALAITIGITAGYFGGVIDECLTFLMNVVLV
HHCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPNLPLLLVLASFIGEASPTVIALIIGFTSWAYGARVIRAQTLALREKEFVIAAEVLGEP
HCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AWRIILVEILPNLISIIGVSFIGSIIYAIVTEATLEFLGLGDPTVVSWGIMLYNAQTSSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEEEECCCCCE
ILVGAWWEILAPCFAIATLGAGLALLNFAIDEIANPQLRSHKGLNRWKKLAAPVAAPQER
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHCCCCCCCCC
TA
CC
>Mature Secondary Structure
MRMPTILKILLGNKKAAFGLFIVVSFVLMALFAPLLASNEPTKRVSRPHQPPSAEYVMGT
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCEEECC
TRMGHDIWSQFANGARISLMVGFGAGILVCALAITIGITAGYFGGVIDECLTFLMNVVLV
HHCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPNLPLLLVLASFIGEASPTVIALIIGFTSWAYGARVIRAQTLALREKEFVIAAEVLGEP
HCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AWRIILVEILPNLISIIGVSFIGSIIYAIVTEATLEFLGLGDPTVVSWGIMLYNAQTSSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEEEECCCCCE
ILVGAWWEILAPCFAIATLGAGLALLNFAIDEIANPQLRSHKGLNRWKKLAAPVAAPQER
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHCCCCCCCCC
TA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]