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The map label for this gene is dsdA

Identifier: 145299851

GI number: 145299851

Start: 3160332

End: 3161663

Strand: Direct

Name: dsdA

Synonym: ASA_2940

Alternate gene names: 145299851

Gene position: 3160332-3161663 (Clockwise)

Preceding gene: 145299850

Following gene: 145299852

Centisome position: 67.21

GC content: 63.36

Gene sequence:

>1332_bases
ATGAAAAACATCGACGTACAACAGCTCACCAACCAATTCCCGCTGGTACAATCCCTGATCGCGCTCGAGCCCGTGACCTG
GTTCAACCCCAAGGCCAGCACGCTGGCGGTTGGCCTGCCCTATGTGGGACTGGATGGCAGCGATGTGGCGGATGCCTCCG
CCCGGCTTGCCCGCTTCGCCCCCTACATGTGCGAAGCCTTCCCCGAGACCCGCGCCAGCAAGGGCATTCTGGAGTCCGAG
ATCGTCGCCATCCCGGCGATGCAGGCAACGCTCAATACGCGTTACGGTGTCGAGGTCACCGGCAAACTGCTGCTGAAAAA
AGACAGTCACCTGCCCATCTCCGGCTCCATCAAGGCACGCGGCGGCATCTACGAGGTGCTGACCCACGCCGAACAGCTGG
CGATCAAGGCCGGGTTGCTCTGCGAAGAGGACGACTATCGCAAGCTTTTCAGCGAGGAGTTTCGCCAGTTCTTCGGCCAG
TACAGCATTGCCGTGGGATCGACCGGCAACCTCGGCATGTCCATCGGCATCATGAGCGCCAAGCTCGGCTTCACCGTCAC
CGTCCACATGTCTGCCGATGCGCGGGAGTGGAAGAAGCGCAAGCTGCGCGAACACGGCGTCATAGTGGTGGAGTATGCCG
AGGATTACGGGGTGGCGGTGGAGCAGGGCCGCAAGGAGGCCGAACGCGACCCCAACTGCTTCTTTATCGACGACGAGAAC
TCCCGCACCCTGTTCCTCGGCTACTCGGTAGCCGGTGAGCGGGTGAAAACACAGTTCGACCAGATGGGCATCAAGGTGGA
TGCCGAGCATCCGCTGTTCGTCTATCTGCCTTGCGGCGTCGGCGGTGGCCCGGGCGGCGTGGCCTTTGGCCTGAAACTCG
CGTTCGGGGATAACGTCCACTGCCTGTTTGCCGAGCCGACCCACTCCCCCTGCATGCTGCTGGGGGTCCACACCGGCCTG
CACGATCAGATTTCGGTGCAGGATCTGGGGATAGACAACCTCACCGCCGCCGACGGTCTGGCGGTGGGGCGTGCATCCGG
CTTCGTCGGCCGCGCCATGGAGCGGCTGCTTGATGGTTTCTATACCCTGAGCGATCAGGAGATGTATGACCTGCTGGGGC
TGCTGGCGCGGGATGAGCAGATCAAACTCGAACCCTCAGCCTTGGCCGGCATGCCGGGCCCGTGGCGCATCGCGGCCGAT
CGCGAGTGGCAGACGGAACGCGGCTTCGATGCCGCTACCCTGGCCCGGGCCACCCATCTGGTATGGGCCACCGGCGGCGG
CATGGTGCCCGCCGAGGAGATGGAAAAATACCTGGCCACCGCCGAAATTTGA

Upstream 100 bases:

>100_bases
ACGCTCAAGTACTACACTACCGCCACCTTTGTCGCCTCCCTGATGGCGCTGGCCGGTACTTTCCTGCTCTCCTATATCGT
GTAACAAGACCGAGAACCCT

Downstream 100 bases:

>100_bases
TCTTTTTTCACCCGAAAAACCCGCCACCCTGGCGGGTTTTTCTCTTCATGGATCAGCAAGATGGCACATCCTTTGCCCTG
AACATGAGCACATCACGTCT

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MKNIDVQQLTNQFPLVQSLIALEPVTWFNPKASTLAVGLPYVGLDGSDVADASARLARFAPYMCEAFPETRASKGILESE
IVAIPAMQATLNTRYGVEVTGKLLLKKDSHLPISGSIKARGGIYEVLTHAEQLAIKAGLLCEEDDYRKLFSEEFRQFFGQ
YSIAVGSTGNLGMSIGIMSAKLGFTVTVHMSADAREWKKRKLREHGVIVVEYAEDYGVAVEQGRKEAERDPNCFFIDDEN
SRTLFLGYSVAGERVKTQFDQMGIKVDAEHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCLFAEPTHSPCMLLGVHTGL
HDQISVQDLGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLSDQEMYDLLGLLARDEQIKLEPSALAGMPGPWRIAAD
REWQTERGFDAATLARATHLVWATGGGMVPAEEMEKYLATAEI

Sequences:

>Translated_443_residues
MKNIDVQQLTNQFPLVQSLIALEPVTWFNPKASTLAVGLPYVGLDGSDVADASARLARFAPYMCEAFPETRASKGILESE
IVAIPAMQATLNTRYGVEVTGKLLLKKDSHLPISGSIKARGGIYEVLTHAEQLAIKAGLLCEEDDYRKLFSEEFRQFFGQ
YSIAVGSTGNLGMSIGIMSAKLGFTVTVHMSADAREWKKRKLREHGVIVVEYAEDYGVAVEQGRKEAERDPNCFFIDDEN
SRTLFLGYSVAGERVKTQFDQMGIKVDAEHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCLFAEPTHSPCMLLGVHTGL
HDQISVQDLGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLSDQEMYDLLGLLARDEQIKLEPSALAGMPGPWRIAAD
REWQTERGFDAATLARATHLVWATGGGMVPAEEMEKYLATAEI
>Mature_443_residues
MKNIDVQQLTNQFPLVQSLIALEPVTWFNPKASTLAVGLPYVGLDGSDVADASARLARFAPYMCEAFPETRASKGILESE
IVAIPAMQATLNTRYGVEVTGKLLLKKDSHLPISGSIKARGGIYEVLTHAEQLAIKAGLLCEEDDYRKLFSEEFRQFFGQ
YSIAVGSTGNLGMSIGIMSAKLGFTVTVHMSADAREWKKRKLREHGVIVVEYAEDYGVAVEQGRKEAERDPNCFFIDDEN
SRTLFLGYSVAGERVKTQFDQMGIKVDAEHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCLFAEPTHSPCMLLGVHTGL
HDQISVQDLGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLSDQEMYDLLGLLARDEQIKLEPSALAGMPGPWRIAAD
REWQTERGFDAATLARATHLVWATGGGMVPAEEMEKYLATAEI

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily

Homologues:

Organism=Escherichia coli, GI1788708, Length=439, Percent_Identity=74.9430523917995, Blast_Score=664, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHD_AERS4 (A4SPX2)

Other databases:

- EMBL:   CP000644
- RefSeq:   YP_001142692.1
- ProteinModelPortal:   A4SPX2
- STRING:   A4SPX2
- GeneID:   4994610
- GenomeReviews:   CP000644_GR
- KEGG:   asa:ASA_2940
- eggNOG:   COG3048
- HOGENOM:   HBG288722
- OMA:   WKKDLLR
- PhylomeDB:   A4SPX2
- ProtClustDB:   PRK02991
- BioCyc:   ASAL382245:ASA_2940-MONOMER
- HAMAP:   MF_01030
- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634
- PANTHER:   PTHR10314:SF9
- TIGRFAMs:   TIGR02035

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.3.1.18

Molecular weight: Translated: 48248; Mature: 48248

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIDVQQLTNQFPLVQSLIALEPVTWFNPKASTLAVGLPYVGLDGSDVADASARLARFA
CCCCCHHHHHHCCHHHHHHHHHCCCEECCCCCCEEEEECCEECCCCCCCCHHHHHHHHHH
PYMCEAFPETRASKGILESEIVAIPAMQATLNTRYGVEVTGKLLLKKDSHLPISGSIKAR
HHHHHHCCHHHHHCCCHHHHEEEECCHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCC
GGIYEVLTHAEQLAIKAGLLCEEDDYRKLFSEEFRQFFGQYSIAVGSTGNLGMSIGIMSA
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEE
KLGFTVTVHMSADAREWKKRKLREHGVIVVEYAEDYGVAVEQGRKEAERDPNCFFIDDEN
ECCEEEEEEECCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHCCHHHCCCCCEEEEECCC
SRTLFLGYSVAGERVKTQFDQMGIKVDAEHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVH
CEEEEEEECCCCHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCEEEEEEEEECCCEE
CLFAEPTHSPCMLLGVHTGLHDQISVQDLGIDNLTAADGLAVGRASGFVGRAMERLLDGF
EEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCEECCCCCHHHHHHHHHHHHH
YTLSDQEMYDLLGLLARDEQIKLEPSALAGMPGPWRIAADREWQTERGFDAATLARATHL
CCCCCHHHHHHHHHHHCCCCEEECHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHEEE
VWATGGGMVPAEEMEKYLATAEI
EEECCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKNIDVQQLTNQFPLVQSLIALEPVTWFNPKASTLAVGLPYVGLDGSDVADASARLARFA
CCCCCHHHHHHCCHHHHHHHHHCCCEECCCCCCEEEEECCEECCCCCCCCHHHHHHHHHH
PYMCEAFPETRASKGILESEIVAIPAMQATLNTRYGVEVTGKLLLKKDSHLPISGSIKAR
HHHHHHCCHHHHHCCCHHHHEEEECCHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCC
GGIYEVLTHAEQLAIKAGLLCEEDDYRKLFSEEFRQFFGQYSIAVGSTGNLGMSIGIMSA
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEE
KLGFTVTVHMSADAREWKKRKLREHGVIVVEYAEDYGVAVEQGRKEAERDPNCFFIDDEN
ECCEEEEEEECCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHCCHHHCCCCCEEEEECCC
SRTLFLGYSVAGERVKTQFDQMGIKVDAEHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVH
CEEEEEEECCCCHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCEEEEEEEEECCCEE
CLFAEPTHSPCMLLGVHTGLHDQISVQDLGIDNLTAADGLAVGRASGFVGRAMERLLDGF
EEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCEECCCCCHHHHHHHHHHHHH
YTLSDQEMYDLLGLLARDEQIKLEPSALAGMPGPWRIAADREWQTERGFDAATLARATHL
CCCCCHHHHHHHHHHHCCCCEEECHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHEEE
VWATGGGMVPAEEMEKYLATAEI
EEECCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA