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The map label for this gene is yisS [H]

Identifier: 145296072

GI number: 145296072

Start: 2192451

End: 2193464

Strand: Reverse

Name: yisS [H]

Synonym: cgR_1994

Alternate gene names: 145296072

Gene position: 2193464-2192451 (Counterclockwise)

Preceding gene: 145296074

Following gene: 145296071

Centisome position: 66.18

GC content: 57.59

Gene sequence:

>1014_bases
ATGTCAGTCAAACTTGCCCTCATCGGTGCTGGACGCATCGGATCAAATCACGCACGCCTGATCACAAACCACGTGATCGG
TTCTGAACTGGTCGCCGTAGTTGACCCAACTCCCAACGCAGAAACCCTCGCTGATGAATTGGGCGCCGTTGCGTTCTCTA
ACCCAGATGATGTACTGACCCGCGATGACATTGACGCGGTTTTGATTGCTACACCAGCACGAACCCACGCGGATCTCGTG
GTCAAAGCAGCGGCAGCGGGCAAGCACGTGTTTGTGGAAAAGCCCATGGCCGTCACCCTCGAGGACGCAGATCGTGCCAT
CAACGCAGCAAGCGAAGCAAACACTGTCCTGCAGGTGGGCTTCAATCGTCGTTTCGCGGCAGGTTTCGCTGCAGCACGCG
CACGCATTGACGCAGGCGATATCGGCACCCCACAGCTGCTTCGTTCCGTGACCCGCGATCCAGGCCCATTCACCGCTGAC
CCCAACAAGATCCCTCAGTGGACCATCTTCCTGGAAACCCTCATCCACGATTTCGATGCGCTGTGCTACCTCAACCCAGG
CGCAACCCCAGTGGAAGTAACCGCTCACGCTGATTGCCTCGTCGTTCCAGAAGCTGCTGGCACTGGCTTCCTCGACACCG
CAGTGGTGACTGTCCGTTTTGATAACGGAGCAATTGGTACTGCAGAAGCAAGCTTCAGCGCAGCCTATGGTTATGACGTT
CGCGGTGAAGTCTTCGGATCCAAGGGCATGATGACCGCAGGCGACGCGCGCGCAACTAACATGACTTTCTACGGCGCTGA
GGGCATCGCGGCTGCCACCTCACCTGCGGATACCGATCTGCTCTCCGATGCTTACCGAGCTGAATTCCAAGCTTTCGTCG
ACTCCATCCGCACCAACACCCCTTCCAAGGTTCCAGGCGAAGCTGCACGCACCGCACTACTCATCGCACTCGGCGCCATC
CGAAGCGTAGAAACCGGCGCAACCATCAACCTTGCTGAAAGCATCGAGGTTTAA

Upstream 100 bases:

>100_bases
CATCTTTACAGGAAACCCCTTGACGGCATCAATGGGTGGTATCTAGTATCGACTAGAACGTTATAGTAGAACGTTCTAGT
AAAACTTGGAAGGATGAAAA

Downstream 100 bases:

>100_bases
CCATGACTTTTAAACTCGCAGCATGCGCAGAGATGATCTACCAGGACCTACCTTTTGAGGAGAGGGTCAAGACGATCTCT
GATCAGGGATTCCTCGTGGA

Product: hypothetical protein

Products: 2,4,6/3,5-pentahydroxycyclohexanone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSVKLALIGAGRIGSNHARLITNHVIGSELVAVVDPTPNAETLADELGAVAFSNPDDVLTRDDIDAVLIATPARTHADLV
VKAAAAGKHVFVEKPMAVTLEDADRAINAASEANTVLQVGFNRRFAAGFAAARARIDAGDIGTPQLLRSVTRDPGPFTAD
PNKIPQWTIFLETLIHDFDALCYLNPGATPVEVTAHADCLVVPEAAGTGFLDTAVVTVRFDNGAIGTAEASFSAAYGYDV
RGEVFGSKGMMTAGDARATNMTFYGAEGIAAATSPADTDLLSDAYRAEFQAFVDSIRTNTPSKVPGEAARTALLIALGAI
RSVETGATINLAESIEV

Sequences:

>Translated_337_residues
MSVKLALIGAGRIGSNHARLITNHVIGSELVAVVDPTPNAETLADELGAVAFSNPDDVLTRDDIDAVLIATPARTHADLV
VKAAAAGKHVFVEKPMAVTLEDADRAINAASEANTVLQVGFNRRFAAGFAAARARIDAGDIGTPQLLRSVTRDPGPFTAD
PNKIPQWTIFLETLIHDFDALCYLNPGATPVEVTAHADCLVVPEAAGTGFLDTAVVTVRFDNGAIGTAEASFSAAYGYDV
RGEVFGSKGMMTAGDARATNMTFYGAEGIAAATSPADTDLLSDAYRAEFQAFVDSIRTNTPSKVPGEAARTALLIALGAI
RSVETGATINLAESIEV
>Mature_336_residues
SVKLALIGAGRIGSNHARLITNHVIGSELVAVVDPTPNAETLADELGAVAFSNPDDVLTRDDIDAVLIATPARTHADLVV
KAAAAGKHVFVEKPMAVTLEDADRAINAASEANTVLQVGFNRRFAAGFAAARARIDAGDIGTPQLLRSVTRDPGPFTADP
NKIPQWTIFLETLIHDFDALCYLNPGATPVEVTAHADCLVVPEAAGTGFLDTAVVTVRFDNGAIGTAEASFSAAYGYDVR
GEVFGSKGMMTAGDARATNMTFYGAEGIAAATSPADTDLLSDAYRAEFQAFVDSIRTNTPSKVPGEAARTALLIALGAIR
SVETGATINLAESIEV

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=278, Percent_Identity=29.136690647482, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787574, Length=260, Percent_Identity=27.3076923076923, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081947, Length=142, Percent_Identity=33.8028169014084, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.1.1.18

Molecular weight: Translated: 35084; Mature: 34953

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKLALIGAGRIGSNHARLITNHVIGSELVAVVDPTPNAETLADELGAVAFSNPDDVLT
CCEEEEEEECCCCCCCCCEEHHHHHCCCCEEEEECCCCCHHHHHHHHCCEEECCCCCCCC
RDDIDAVLIATPARTHADLVVKAAAAGKHVFVEKPMAVTLEDADRAINAASEANTVLQVG
CCCCCEEEEECCCCCCCCEEEEECCCCCEEEEECCCEEEECCHHHHHHHHHHCCEEEEEC
FNRRFAAGFAAARARIDAGDIGTPQLLRSVTRDPGPFTADPNKIPQWTIFLETLIHDFDA
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCE
LCYLNPGATPVEVTAHADCLVVPEAAGTGFLDTAVVTVRFDNGAIGTAEASFSAAYGYDV
EEEECCCCCEEEEEECCCEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCEECCCCC
RGEVFGSKGMMTAGDARATNMTFYGAEGIAAATSPADTDLLSDAYRAEFQAFVDSIRTNT
CCEEECCCCCEECCCCCCCEEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PSKVPGEAARTALLIALGAIRSVETGATINLAESIEV
CCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
>Mature Secondary Structure 
SVKLALIGAGRIGSNHARLITNHVIGSELVAVVDPTPNAETLADELGAVAFSNPDDVLT
CEEEEEEECCCCCCCCCEEHHHHHCCCCEEEEECCCCCHHHHHHHHCCEEECCCCCCCC
RDDIDAVLIATPARTHADLVVKAAAAGKHVFVEKPMAVTLEDADRAINAASEANTVLQVG
CCCCCEEEEECCCCCCCCEEEEECCCCCEEEEECCCEEEECCHHHHHHHHHHCCEEEEEC
FNRRFAAGFAAARARIDAGDIGTPQLLRSVTRDPGPFTADPNKIPQWTIFLETLIHDFDA
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCE
LCYLNPGATPVEVTAHADCLVVPEAAGTGFLDTAVVTVRFDNGAIGTAEASFSAAYGYDV
EEEECCCCCEEEEEECCCEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCEECCCCC
RGEVFGSKGMMTAGDARATNMTFYGAEGIAAATSPADTDLLSDAYRAEFQAFVDSIRTNT
CCEEECCCCCEECCCCCCCEEEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PSKVPGEAARTALLIALGAIRSVETGATINLAESIEV
CCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: myo-inositol; NAD+

Specific reaction: myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377; 8407808 [H]