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The map label for this gene is rbsR [H]

Identifier: 145296008

GI number: 145296008

Start: 2120675

End: 2121652

Strand: Reverse

Name: rbsR [H]

Synonym: cgR_1932

Alternate gene names: 145296008

Gene position: 2121652-2120675 (Counterclockwise)

Preceding gene: 145296009

Following gene: 145296007

Centisome position: 64.02

GC content: 54.29

Gene sequence:

>978_bases
ATGTCAGCAAAATCGAGCCTCAAGGAAGTGGCTGAGTTAGCTGGCGTCGGTTACGCCACAGCCTCGAGGGCGTTATCCGG
CAAGGGGTATGTGTCCTCGCAAACGCGGGAGAAAGTTCAGGCGGTGGCTAAAGAGCTGAACTATGTACCAAATCAGCTGG
CCAAGGCGTTGCGGGAACATCGCAGTGCCTTGGTGGGGGTCATTGTTCCGGATTTGTCCAATGAGTATTATTCGGAATCG
CTGCAGACTATTCAGCAGGATCTGAAAGCTGCTGGCTATCAAATGCTGGTTGCGGAGGCCAACAGTGTGCAGGCGCAGGA
CGTGGTGATGGAATCGTTGATTTCGATTCAAGCTGCAGGAATTATCCACGTTCCAGTGGTCGGCTCAATTGCTCCTGAAG
GAATCCCCATGGTGCAGTTGACTCGTGGTGAATTGGGTCCTGGTTTCCCTCGGGTGTCGTGTGATGATGAGGCTGGGTTT
TTCCAGCTGACCGAGTCGGTGCTGGGCGGCAGCGGAATGAACATTGCTGCTTTGGTTGGTGAAGAATCACTTTCCACCAC
GCAGGAACGAATGCGCGGTATTAGTCATGCGGCGTCGATATATGGGGCTGAGGTGACGTTCCATTTTGGCCACTATTCTG
TCGAATCTGGCGAAGAGATGGCTCAGGTGGTGTTTAACAACGGCCTTCCCGATGCATTGATTGTGGCGTCTCCTCGGCTG
ATGGCTGGGGTGATGCGTGCTTTTACTCGCCTGAATGTCCGCGTTCCCCACGATGTGGTGATTGGTGGTTATGACGATCT
TGAGTGGTACAGCTTTGTCGGCGCGGGGATCACCACGTTTGTTCCACCGCATGAGGAGATGGGGAAAGAGGCCGTGCGCT
TGTTGGTAGATCTGATTGAAAATCCTGAACTTCCCACCGGCGATGTGGTTTTGCAGGGGCAGGTGATCCTTCGGGGGTCG
AGCACACATTCCGGGTAG

Upstream 100 bases:

>100_bases
CGTATCGATCACAATCTGGTTGGTTATCGGTGGTTTGTGGATGAATGTCATCGGACTCTGGTAATCGAAGTCAAAGGCAA
AAAGGTAAGGGTGTGTGAAG

Downstream 100 bases:

>100_bases
AATTGCCCAAATGTCATCAATTTCTCGAACGATTGCTCTCGAACTCGGCGTCAAAGATGAACAAGTCGAGGCCGCCATCA
AGCTCTTGGATGAAGGAAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSAKSSLKEVAELAGVGYATASRALSGKGYVSSQTREKVQAVAKELNYVPNQLAKALREHRSALVGVIVPDLSNEYYSES
LQTIQQDLKAAGYQMLVAEANSVQAQDVVMESLISIQAAGIIHVPVVGSIAPEGIPMVQLTRGELGPGFPRVSCDDEAGF
FQLTESVLGGSGMNIAALVGEESLSTTQERMRGISHAASIYGAEVTFHFGHYSVESGEEMAQVVFNNGLPDALIVASPRL
MAGVMRAFTRLNVRVPHDVVIGGYDDLEWYSFVGAGITTFVPPHEEMGKEAVRLLVDLIENPELPTGDVVLQGQVILRGS
STHSG

Sequences:

>Translated_325_residues
MSAKSSLKEVAELAGVGYATASRALSGKGYVSSQTREKVQAVAKELNYVPNQLAKALREHRSALVGVIVPDLSNEYYSES
LQTIQQDLKAAGYQMLVAEANSVQAQDVVMESLISIQAAGIIHVPVVGSIAPEGIPMVQLTRGELGPGFPRVSCDDEAGF
FQLTESVLGGSGMNIAALVGEESLSTTQERMRGISHAASIYGAEVTFHFGHYSVESGEEMAQVVFNNGLPDALIVASPRL
MAGVMRAFTRLNVRVPHDVVIGGYDDLEWYSFVGAGITTFVPPHEEMGKEAVRLLVDLIENPELPTGDVVLQGQVILRGS
STHSG
>Mature_324_residues
SAKSSLKEVAELAGVGYATASRALSGKGYVSSQTREKVQAVAKELNYVPNQLAKALREHRSALVGVIVPDLSNEYYSESL
QTIQQDLKAAGYQMLVAEANSVQAQDVVMESLISIQAAGIIHVPVVGSIAPEGIPMVQLTRGELGPGFPRVSCDDEAGFF
QLTESVLGGSGMNIAALVGEESLSTTQERMRGISHAASIYGAEVTFHFGHYSVESGEEMAQVVFNNGLPDALIVASPRLM
AGVMRAFTRLNVRVPHDVVIGGYDDLEWYSFVGAGITTFVPPHEEMGKEAVRLLVDLIENPELPTGDVVLQGQVILRGSS
THSG

Specific function: Transcriptional repressor for the ribose rbsDACBK operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=330, Percent_Identity=26.6666666666667, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1790194, Length=343, Percent_Identity=26.2390670553936, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786268, Length=313, Percent_Identity=27.1565495207668, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789068, Length=330, Percent_Identity=26.969696969697, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786540, Length=304, Percent_Identity=29.6052631578947, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1787948, Length=332, Percent_Identity=24.0963855421687, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789202, Length=329, Percent_Identity=24.9240121580547, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790715, Length=333, Percent_Identity=21.9219219219219, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI48994940, Length=293, Percent_Identity=25.938566552901, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787580, Length=327, Percent_Identity=25.3822629969419, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788474, Length=304, Percent_Identity=27.9605263157895, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787906, Length=213, Percent_Identity=31.4553990610329, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790689, Length=311, Percent_Identity=25.7234726688103, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 34645; Mature: 34514

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2 ; PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKSSLKEVAELAGVGYATASRALSGKGYVSSQTREKVQAVAKELNYVPNQLAKALREH
CCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RSALVGVIVPDLSNEYYSESLQTIQQDLKAAGYQMLVAEANSVQAQDVVMESLISIQAAG
HHHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
IIHVPVVGSIAPEGIPMVQLTRGELGPGFPRVSCDDEAGFFQLTESVLGGSGMNIAALVG
EEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEC
EESLSTTQERMRGISHAASIYGAEVTFHFGHYSVESGEEMAQVVFNNGLPDALIVASPRL
CHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEECCCHHHHHHHHHCCCCCCCEEECCCHH
MAGVMRAFTRLNVRVPHDVVIGGYDDLEWYSFVGAGITTFVPPHEEMGKEAVRLLVDLIE
HHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHH
NPELPTGDVVLQGQVILRGSSTHSG
CCCCCCCCEEEECEEEEECCCCCCC
>Mature Secondary Structure 
SAKSSLKEVAELAGVGYATASRALSGKGYVSSQTREKVQAVAKELNYVPNQLAKALREH
CCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RSALVGVIVPDLSNEYYSESLQTIQQDLKAAGYQMLVAEANSVQAQDVVMESLISIQAAG
HHHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
IIHVPVVGSIAPEGIPMVQLTRGELGPGFPRVSCDDEAGFFQLTESVLGGSGMNIAALVG
EEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEC
EESLSTTQERMRGISHAASIYGAEVTFHFGHYSVESGEEMAQVVFNNGLPDALIVASPRL
CHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEECCCHHHHHHHHHCCCCCCCEEECCCHH
MAGVMRAFTRLNVRVPHDVVIGGYDDLEWYSFVGAGITTFVPPHEEMGKEAVRLLVDLIE
HHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHH
NPELPTGDVVLQGQVILRGSSTHSG
CCCCCCCCEEEECEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]