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The map label for this gene is ftsK [H]

Identifier: 145295872

GI number: 145295872

Start: 1992317

End: 1995091

Strand: Reverse

Name: ftsK [H]

Synonym: cgR_1797

Alternate gene names: 145295872

Gene position: 1995091-1992317 (Counterclockwise)

Preceding gene: 145295873

Following gene: 145295871

Centisome position: 60.2

GC content: 56.61

Gene sequence:

>2775_bases
TTGGGTAAGATGACCCGTTCCATTGGTGAACTTGGTCGTCGTCGAAACGAAGATGTACTCGACGATTTTGATGATTTCGA
GGAGGAGATCGCAACGAAACCCGCCGCACGAAAATCGCGGAGCAAGGCTGTTGAACCTGAGCCGGAATTCGATGAGGATT
TTGATGAGCAATCAGGAAACCGCACTTCTGCCTACGTGGAAGAGCACGCAGACGGCATTGCATTAAGCCTGGTTGGAATT
GCAATTGTCTTGGGCGCTGCGGTGTGGCTGGGCATTGGTGGACCGATTGGCACGTTCATCGCCGATATCGTTCACCTCGC
TATTGGCGCTGGTGCTTGGATCTTGCCGGTCGGCCTCATGGGGTGGGCTGTCGCGCTCATGCTTCGTTACACTCCAGAGC
GTCAAGCTCAGGGCAGGGTGATGTTGGGCATCGGTGTGATCATCGTGTGCATGCTGGCCTTGATTCACCTCTTTGCTGGT
AACCCAGCTGAGTGGGAGGGCCGAAAGACTGCTGGCGGTGCCATCGGTGCGTGGATTGGAACCCCGTTGGAACTGGGATT
CTCCGTGTTCTTGGCGGTGCCGATCCTGCTTCTGCTGCTGTTCTGGGGAGCGTTGAAAACCACAGGAATTTCGATTCGTG
AGTTCATCGAATTTGCGGGTGGCTTCTTTGGCTTCGCAGGATTTAACCGCGATGAAGATGAATTCGACGAGGAAGACGAT
GATCTCTATGGACACGTGGAACGCGAGTTGGAATCCCGCGCGAGCGGTCGTGCACCGAGTAGAACCCCTAGCCGAGCGCT
GCCTAAGGCTGCGCCACGTCGCACCCCACCTCTGACTCCGCCACCGGCACCAGTTCCTGCGCCAGCCCCAACACCTGCGC
GCCGCCCAGCGGCGTCGCTGGATAAGTATCCCGTGGATGACGCGAAGGCCGAGGCCCCCGCGGAACCGCAGGTGAAGCAG
AGGGAGGCGTCGACAAGCATCTTGAAGAAGCCCAGCGTCACCGAAACTGATGAGTTCCCAGCGGTGACCGAGGAAGATCT
GGCGCCGGCGCCGGCGTCGGATGCGGTGGCAGCGTCGAGGGAAAGCATGCGTCAGGCGATTATTGCGCGATCGGGCAAGG
ATCCCGTCGTGGAGAAGAAGCCTGCGGCACCTGCTCCTGTAGCGCCGACCCCTGCCGACATTGTCAGCGATGGCGACAGC
ACTTATGTGTTGCCGAGTGCCGATCTGCTGATTCCAGGCGAGCCAGCGAAGCTTCACTCAGAGACCAACGATCGCATGAT
CGAGGCCATTACTGACGTGTTCAGTGAGTTCAATGTTGATGCGACCGTGACTGGTTTCTCCCGTGGCCCGACAGTCACGC
GCTATGAAATTGAGCTGGGACCTGGTGTGAAGGTTTCTAAAATCACCAACCTGCAATCCAATATTGCCTACGCTGTGGCG
ACTGAGAATGTTCGTCTGCTGACCCCAATTCCAGGTAAATCAGCAGTCGGTATTGAGGTGCCAAACTCTGACCGTGAGAT
GGTTCGTCTGGGTGATGTGCTCAATGCGCGTGCCACCGTGGAAAACAAAGACTCCATGCTCATTGGTTTGGGTAAGGATA
TTGAAGGCGACTTCGTGTCCTACTCCGTGCAGAAAATGCCTCACCTTCTTGTGGCTGGTTCCACCGGTTCTGGTAAGTCG
GCGTTCGTGAACTCGCTGCTGGTGTCACTACTCACGCGTGCAAGGCCAGAAGAAGTTCGTCTGATTCTGGTGGACCCAAA
GATGGTGGAACTCACACCATACGAGGGCATTCCACACCTGATTACGCCGATCATTACCCAACCAAAGAAGGCCGCGGCAG
CACTGCAGTGGCTGGTTGAGGAAATGGAACAGCGCTACATGGACATGAAACAAACCCGTGTGCGCCACATCAAGGACTTC
AACCGCAAGATTAAATCTGGCGAAATTGAGACCCCTCCAGGATCCAAGCGCGAATACCGTGCGTACCCATACATCGTGTG
TGTGGTCGACGAGCTCGCTGACCTGATGATGACCGCACCGAAGGAAATCGAAGAGTCTATCGTGCGCATCACCCAGAAGG
CACGTGCCGCCGGTATCCACCTCGTGCTGGCAACGCAGCGCCCATCCGTGGACGTTGTGACCGGTCTGATCAAGACCAAC
GTTCCTTCACGTTTGGCTTTCGCAACCTCATCGCTAACTGACTCCCGCGTTATTTTGGACCAGGGTGGCGCTGAAAAGCT
GATCGGCATGGGCGACGCGCTGTTCATCCCACAGGGTGCCGGCAAGCCACAACGTATCCAGGGTGCCTTTGTCACCGATG
AAGAAATCCAAGCGGTCGTGGACATGGCCAAGGCTCAGCGCCAGCCTGAATACACCGACGGTGTCACCGAAGATAAGGCT
TCCGAAGCAAAGAAGATCGATGCCGATATCGGAAACGATCTGGAAGATCTCCTCGAAGCAGTCGAACTCGTGGTGACCTC
ACAAATGGGATCCACCTCCATGCTGCAGCGCAAACTGCGCATCGGTTTTGCCAAGGCCGGACGCCTCATGGACCTCATGG
AAACCCGCGGTGTGGTGGGCCCATCCGAAGGCTCTAAGGCTCGTGAAGTTTTGGTCAAGCCAGAAGAGCTGGAAACCATT
TTGTGGATGCTTAAAGGTGCAGACCCCGCCGACGCACCGAAGGAAGAGACCTGGGATGACGAGGTGGCAGCGGAAGCTGA
AGAAGCAGCCAACACCACGGTCGTGCAGGCTGATCCTTCCAAGGGAGTGTTTTAA

Upstream 100 bases:

>100_bases
CGCTCGACGCGCTGCTGATACTTCCGAAGAACGGACCGGCAGCGCATTTCGCGCTGTGGGATCCGGTATCGGAACGCTAT
TTGGTGCCACCGCGAGTGGC

Downstream 100 bases:

>100_bases
GGCGCTAATGGCGGCTTGAGGCTCTCTGTCCTTAGGACCGATGGGTCGGGCATGTTGTCGCAGTTTCAGGTACTGGACTG
TGAGAATGTGCCCGTTTCTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 924; Mature: 923

Protein sequence:

>924_residues
MGKMTRSIGELGRRRNEDVLDDFDDFEEEIATKPAARKSRSKAVEPEPEFDEDFDEQSGNRTSAYVEEHADGIALSLVGI
AIVLGAAVWLGIGGPIGTFIADIVHLAIGAGAWILPVGLMGWAVALMLRYTPERQAQGRVMLGIGVIIVCMLALIHLFAG
NPAEWEGRKTAGGAIGAWIGTPLELGFSVFLAVPILLLLLFWGALKTTGISIREFIEFAGGFFGFAGFNRDEDEFDEEDD
DLYGHVERELESRASGRAPSRTPSRALPKAAPRRTPPLTPPPAPVPAPAPTPARRPAASLDKYPVDDAKAEAPAEPQVKQ
REASTSILKKPSVTETDEFPAVTEEDLAPAPASDAVAASRESMRQAIIARSGKDPVVEKKPAAPAPVAPTPADIVSDGDS
TYVLPSADLLIPGEPAKLHSETNDRMIEAITDVFSEFNVDATVTGFSRGPTVTRYEIELGPGVKVSKITNLQSNIAYAVA
TENVRLLTPIPGKSAVGIEVPNSDREMVRLGDVLNARATVENKDSMLIGLGKDIEGDFVSYSVQKMPHLLVAGSTGSGKS
AFVNSLLVSLLTRARPEEVRLILVDPKMVELTPYEGIPHLITPIITQPKKAAAALQWLVEEMEQRYMDMKQTRVRHIKDF
NRKIKSGEIETPPGSKREYRAYPYIVCVVDELADLMMTAPKEIEESIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTN
VPSRLAFATSSLTDSRVILDQGGAEKLIGMGDALFIPQGAGKPQRIQGAFVTDEEIQAVVDMAKAQRQPEYTDGVTEDKA
SEAKKIDADIGNDLEDLLEAVELVVTSQMGSTSMLQRKLRIGFAKAGRLMDLMETRGVVGPSEGSKAREVLVKPEELETI
LWMLKGADPADAPKEETWDDEVAAEAEEAANTTVVQADPSKGVF

Sequences:

>Translated_924_residues
MGKMTRSIGELGRRRNEDVLDDFDDFEEEIATKPAARKSRSKAVEPEPEFDEDFDEQSGNRTSAYVEEHADGIALSLVGI
AIVLGAAVWLGIGGPIGTFIADIVHLAIGAGAWILPVGLMGWAVALMLRYTPERQAQGRVMLGIGVIIVCMLALIHLFAG
NPAEWEGRKTAGGAIGAWIGTPLELGFSVFLAVPILLLLLFWGALKTTGISIREFIEFAGGFFGFAGFNRDEDEFDEEDD
DLYGHVERELESRASGRAPSRTPSRALPKAAPRRTPPLTPPPAPVPAPAPTPARRPAASLDKYPVDDAKAEAPAEPQVKQ
REASTSILKKPSVTETDEFPAVTEEDLAPAPASDAVAASRESMRQAIIARSGKDPVVEKKPAAPAPVAPTPADIVSDGDS
TYVLPSADLLIPGEPAKLHSETNDRMIEAITDVFSEFNVDATVTGFSRGPTVTRYEIELGPGVKVSKITNLQSNIAYAVA
TENVRLLTPIPGKSAVGIEVPNSDREMVRLGDVLNARATVENKDSMLIGLGKDIEGDFVSYSVQKMPHLLVAGSTGSGKS
AFVNSLLVSLLTRARPEEVRLILVDPKMVELTPYEGIPHLITPIITQPKKAAAALQWLVEEMEQRYMDMKQTRVRHIKDF
NRKIKSGEIETPPGSKREYRAYPYIVCVVDELADLMMTAPKEIEESIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTN
VPSRLAFATSSLTDSRVILDQGGAEKLIGMGDALFIPQGAGKPQRIQGAFVTDEEIQAVVDMAKAQRQPEYTDGVTEDKA
SEAKKIDADIGNDLEDLLEAVELVVTSQMGSTSMLQRKLRIGFAKAGRLMDLMETRGVVGPSEGSKAREVLVKPEELETI
LWMLKGADPADAPKEETWDDEVAAEAEEAANTTVVQADPSKGVF
>Mature_923_residues
GKMTRSIGELGRRRNEDVLDDFDDFEEEIATKPAARKSRSKAVEPEPEFDEDFDEQSGNRTSAYVEEHADGIALSLVGIA
IVLGAAVWLGIGGPIGTFIADIVHLAIGAGAWILPVGLMGWAVALMLRYTPERQAQGRVMLGIGVIIVCMLALIHLFAGN
PAEWEGRKTAGGAIGAWIGTPLELGFSVFLAVPILLLLLFWGALKTTGISIREFIEFAGGFFGFAGFNRDEDEFDEEDDD
LYGHVERELESRASGRAPSRTPSRALPKAAPRRTPPLTPPPAPVPAPAPTPARRPAASLDKYPVDDAKAEAPAEPQVKQR
EASTSILKKPSVTETDEFPAVTEEDLAPAPASDAVAASRESMRQAIIARSGKDPVVEKKPAAPAPVAPTPADIVSDGDST
YVLPSADLLIPGEPAKLHSETNDRMIEAITDVFSEFNVDATVTGFSRGPTVTRYEIELGPGVKVSKITNLQSNIAYAVAT
ENVRLLTPIPGKSAVGIEVPNSDREMVRLGDVLNARATVENKDSMLIGLGKDIEGDFVSYSVQKMPHLLVAGSTGSGKSA
FVNSLLVSLLTRARPEEVRLILVDPKMVELTPYEGIPHLITPIITQPKKAAAALQWLVEEMEQRYMDMKQTRVRHIKDFN
RKIKSGEIETPPGSKREYRAYPYIVCVVDELADLMMTAPKEIEESIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNV
PSRLAFATSSLTDSRVILDQGGAEKLIGMGDALFIPQGAGKPQRIQGAFVTDEEIQAVVDMAKAQRQPEYTDGVTEDKAS
EAKKIDADIGNDLEDLLEAVELVVTSQMGSTSMLQRKLRIGFAKAGRLMDLMETRGVVGPSEGSKAREVLVKPEELETIL
WMLKGADPADAPKEETWDDEVAAEAEEAANTTVVQADPSKGVF

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=506, Percent_Identity=46.2450592885375, Blast_Score=421, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 99748; Mature: 99617

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKMTRSIGELGRRRNEDVLDDFDDFEEEIATKPAARKSRSKAVEPEPEFDEDFDEQSGN
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCHHHCCCC
RTSAYVEEHADGIALSLVGIAIVLGAAVWLGIGGPIGTFIADIVHLAIGAGAWILPVGLM
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
GWAVALMLRYTPERQAQGRVMLGIGVIIVCMLALIHLFAGNPAEWEGRKTAGGAIGAWIG
HHHHHHHHHCCCCHHHCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHC
TPLELGFSVFLAVPILLLLLFWGALKTTGISIREFIEFAGGFFGFAGFNRDEDEFDEEDD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHCCCCCCCCHHHCCCCCC
DLYGHVERELESRASGRAPSRTPSRALPKAAPRRTPPLTPPPAPVPAPAPTPARRPAASL
HHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHC
DKYPVDDAKAEAPAEPQVKQREASTSILKKPSVTETDEFPAVTEEDLAPAPASDAVAASR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHH
ESMRQAIIARSGKDPVVEKKPAAPAPVAPTPADIVSDGDSTYVLPSADLLIPGEPAKLHS
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEECCCCEEECCCCHHHCC
ETNDRMIEAITDVFSEFNVDATVTGFSRGPTVTRYEIELGPGVKVSKITNLQSNIAYAVA
CHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHCEEEEEE
TENVRLLTPIPGKSAVGIEVPNSDREMVRLGDVLNARATVENKDSMLIGLGKDIEGDFVS
ECCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCEECCCCCEEEEECCCCCCHHHH
YSVQKMPHLLVAGSTGSGKSAFVNSLLVSLLTRARPEEVRLILVDPKMVELTPYEGIPHL
HHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCCHHH
ITPIITQPKKAAAALQWLVEEMEQRYMDMKQTRVRHIKDFNRKIKSGEIETPPGSKREYR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
AYPYIVCVVDELADLMMTAPKEIEESIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTN
CCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCC
VPSRLAFATSSLTDSRVILDQGGAEKLIGMGDALFIPQGAGKPQRIQGAFVTDEEIQAVV
CCHHHHHHHHCCCCCEEEECCCCHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHH
DMAKAQRQPEYTDGVTEDKASEAKKIDADIGNDLEDLLEAVELVVTSQMGSTSMLQRKLR
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
IGFAKAGRLMDLMETRGVVGPSEGSKAREVLVKPEELETILWMLKGADPADAPKEETWDD
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCH
EVAAEAEEAANTTVVQADPSKGVF
HHHHHHHHHCCCEEEEECCCCCCC
>Mature Secondary Structure 
GKMTRSIGELGRRRNEDVLDDFDDFEEEIATKPAARKSRSKAVEPEPEFDEDFDEQSGN
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCHHHCCCC
RTSAYVEEHADGIALSLVGIAIVLGAAVWLGIGGPIGTFIADIVHLAIGAGAWILPVGLM
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
GWAVALMLRYTPERQAQGRVMLGIGVIIVCMLALIHLFAGNPAEWEGRKTAGGAIGAWIG
HHHHHHHHHCCCCHHHCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHC
TPLELGFSVFLAVPILLLLLFWGALKTTGISIREFIEFAGGFFGFAGFNRDEDEFDEEDD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHCCCCCCCCHHHCCCCCC
DLYGHVERELESRASGRAPSRTPSRALPKAAPRRTPPLTPPPAPVPAPAPTPARRPAASL
HHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHC
DKYPVDDAKAEAPAEPQVKQREASTSILKKPSVTETDEFPAVTEEDLAPAPASDAVAASR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHH
ESMRQAIIARSGKDPVVEKKPAAPAPVAPTPADIVSDGDSTYVLPSADLLIPGEPAKLHS
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEECCCCEEECCCCHHHCC
ETNDRMIEAITDVFSEFNVDATVTGFSRGPTVTRYEIELGPGVKVSKITNLQSNIAYAVA
CHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHCEEEEEE
TENVRLLTPIPGKSAVGIEVPNSDREMVRLGDVLNARATVENKDSMLIGLGKDIEGDFVS
ECCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCEECCCCCEEEEECCCCCCHHHH
YSVQKMPHLLVAGSTGSGKSAFVNSLLVSLLTRARPEEVRLILVDPKMVELTPYEGIPHL
HHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCCHHH
ITPIITQPKKAAAALQWLVEEMEQRYMDMKQTRVRHIKDFNRKIKSGEIETPPGSKREYR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
AYPYIVCVVDELADLMMTAPKEIEESIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTN
CCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCC
VPSRLAFATSSLTDSRVILDQGGAEKLIGMGDALFIPQGAGKPQRIQGAFVTDEEIQAVV
CCHHHHHHHHCCCCCEEEECCCCHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHH
DMAKAQRQPEYTDGVTEDKASEAKKIDADIGNDLEDLLEAVELVVTSQMGSTSMLQRKLR
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
IGFAKAGRLMDLMETRGVVGPSEGSKAREVLVKPEELETILWMLKGADPADAPKEETWDD
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCH
EVAAEAEEAANTTVVQADPSKGVF
HHHHHHHHHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]