Click here to switch to the map view.

The map label for this gene is pgsA2 [H]

Identifier: 145295869

GI number: 145295869

Start: 1989592

End: 1990197

Strand: Reverse

Name: pgsA2 [H]

Synonym: cgR_1794

Alternate gene names: 145295869

Gene position: 1990197-1989592 (Counterclockwise)

Preceding gene: 145295871

Following gene: 145295868

Centisome position: 60.05

GC content: 51.49

Gene sequence:

>606_bases
GTGAGTGATGTATCAGCAGGCGTAAATGGCGCACAAGATCCAAGCAATCAAGCGGTCAAGCCTTCCAACTGGAACCTTCC
GAACTTCTTGACCAGCTTGCGCATCATTGTCATCCCTTTGTTTGCGTGGCTTACGCTTAAAGGCGAGACGGAAAACAATG
CTTTTGCCTGGTGGGCGTTGATTGTTTTCATTTTGCTCATGATCACCGACAAGCTTGACGGCGATATTGCGCGAGCACGT
GGCCTGGTCACTGACTTTGGCAAGATCGCGGATCCGATTGCCGATAAGGCGTTGATGACCACAGCATTTGTCTGTTTCAA
CATCATCGGCATTTTGCCCTGGTGGGTCACTGCGTTGATTGTGCTTCGAGAGTTCGGCATTACCATCTGGCGTTTCTTCC
AACTGCGCGCTGGAAATGTTGTGCCTGCATCAAAGGGAGGCAAGCTCAAGACTGCTCTGCAGACTGTTGCCGTTGCTCTG
TATCTGTGCCCTTTCCCAAGTTGGATGGATATTCCAAGCCAGATCGTCATGTATGCAGCGCTGATCGTCACCGTGGTCAC
GGGTCTGCAGTACCTGTGGGATTCACGAAAGTCCGCAGAAAGCTAG

Upstream 100 bases:

>100_bases
TTTTTAGGAATAGAGTGGGCTCAAGCTTTGAGGCAAGTTTTTTTGGAGAAATCATTACTAGTCGTAGTCTTCAATTTGGG
TGCAGGTAGGGTGGAACACC

Downstream 100 bases:

>100_bases
ACCATGGCGGAGAATCTGGCGGGGCGAGTGGTGGAGCTGTTGAAATCGCGCGGTGAAACGCTGGGCGTTTTGTGAATCCC
TCACCGCCGGCCTCGCCAGT

Product: hypothetical protein

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MSDVSAGVNGAQDPSNQAVKPSNWNLPNFLTSLRIIVIPLFAWLTLKGETENNAFAWWALIVFILLMITDKLDGDIARAR
GLVTDFGKIADPIADKALMTTAFVCFNIIGILPWWVTALIVLREFGITIWRFFQLRAGNVVPASKGGKLKTALQTVAVAL
YLCPFPSWMDIPSQIVMYAALIVTVVTGLQYLWDSRKSAES

Sequences:

>Translated_201_residues
MSDVSAGVNGAQDPSNQAVKPSNWNLPNFLTSLRIIVIPLFAWLTLKGETENNAFAWWALIVFILLMITDKLDGDIARAR
GLVTDFGKIADPIADKALMTTAFVCFNIIGILPWWVTALIVLREFGITIWRFFQLRAGNVVPASKGGKLKTALQTVAVAL
YLCPFPSWMDIPSQIVMYAALIVTVVTGLQYLWDSRKSAES
>Mature_200_residues
SDVSAGVNGAQDPSNQAVKPSNWNLPNFLTSLRIIVIPLFAWLTLKGETENNAFAWWALIVFILLMITDKLDGDIARARG
LVTDFGKIADPIADKALMTTAFVCFNIIGILPWWVTALIVLREFGITIWRFFQLRAGNVVPASKGGKLKTALQTVAVALY
LCPFPSWMDIPSQIVMYAALIVTVVTGLQYLWDSRKSAES

Specific function: This Protein Catalyzes The Committed Step To The Synthesis Of The Acidic Phospholipids. [C]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=177, Percent_Identity=33.8983050847458, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71984838, Length=209, Percent_Identity=27.2727272727273, Blast_Score=63, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71984834, Length=209, Percent_Identity=27.2727272727273, Blast_Score=63, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22191; Mature: 22060

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVSAGVNGAQDPSNQAVKPSNWNLPNFLTSLRIIVIPLFAWLTLKGETENNAFAWWAL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
IVFILLMITDKLDGDIARARGLVTDFGKIADPIADKALMTTAFVCFNIIGILPWWVTALI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLREFGITIWRFFQLRAGNVVPASKGGKLKTALQTVAVALYLCPFPSWMDIPSQIVMYAA
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHH
LIVTVVTGLQYLWDSRKSAES
HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SDVSAGVNGAQDPSNQAVKPSNWNLPNFLTSLRIIVIPLFAWLTLKGETENNAFAWWAL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
IVFILLMITDKLDGDIARARGLVTDFGKIADPIADKALMTTAFVCFNIIGILPWWVTALI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLREFGITIWRFFQLRAGNVVPASKGGKLKTALQTVAVALYLCPFPSWMDIPSQIVMYAA
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHH
LIVTVVTGLQYLWDSRKSAES
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036; 10889206 [H]