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The map label for this gene is rutG [H]

Identifier: 145295844

GI number: 145295844

Start: 1966388

End: 1967677

Strand: Reverse

Name: rutG [H]

Synonym: cgR_1769

Alternate gene names: 145295844

Gene position: 1967677-1966388 (Counterclockwise)

Preceding gene: 145295845

Following gene: 145295843

Centisome position: 59.37

GC content: 56.59

Gene sequence:

>1290_bases
GTGCTCGTGACTTCAACATGGGGATGGACCGTCCACGGAGACGGCAAAAAGATCGAACCCGGCGCAGTTGTCGCTCCTAA
AGAGCGCCTGAGCTGGGGGCGCACAATTGGAATCGGTATGCAGCACGTGATCGCCATGTTCGGCGCCACGCTCCTGGTTC
CCACACTCACCGGATTTCCGGTCAACACCACACTTTTATTCTCTGGTCTGGGAACAATCCTGTTCCTGTTGATCACCAGA
AACCGACTACCCTCGTACCTGGGTAGTTCTTTTGCTTTCATTGCACCTTTAACCGCAACCCAAGTCCATGGCATTGGCGT
GCAGATCGGTGGCATTCTTGTCGCAGGTCTCGTGCTCGTCGCCATTGGATTTGTGGTGAAAGCAGCGGGCAAACGCGTTA
TTGATGCTGTCATGCCACCCGCTGTCACCGGTGCGATCGTGGCACTCATCGGCCTGAACCTGGCACCAACCGCGGCAGGA
AACTTCTCCAGCCAACCACTGGTTGCCACGGTGACCCTCTTTGCCATTTTGATCGCTACCGTTGCAGGCCGCGGAATGAT
TGCTCGCCTGGGCATTTTGATCGGTGTGGTGATCGGCTGGGTTTTCGCAGCTATCACCGGCAACCTCTCAGAAGGCGCAG
CAGACACCATCCGTGAAGCAGCATGGTTCGGACTGCCACAGTTCCACAAGCCGGAATTCCAGCTTTCTGCCATTTTGGTG
ACACTGCCAGTCATCATCGTGCTCATCGCTGAAAACGTCGGCCACGTCAAAGCCGTTTCAGAGATGACAGGGGAGGACCT
CGATGACCTCGCTGGCGACGCACTTATCGCAGACGGATTCGGCACCACCCTCGCAGGTGCCTTCGGTGGATCCGGCACCA
CCACCTACGCAGAAAACATCGGCGTCATGGCGGCCACCCGCGTATATTCCACCGCTGCGTACTGGGTTGCCGCGTGCACC
GCCATCGCCCTGGCCTTCATCCCCAAATTCGGTGCGCTGATCTTCACCATCCCCGCCGGCGTGCTGGGTGGGGCATGTTT
GGTTCTTTACGGCCTAATCGGTATGCTCGGCATTCGTATCTGGCAAGACAACAAGGTCAACTTCAACAATCCAGTGAATC
TGACCATGGCTGCCGTTGCTTTGGTTGCAGGCATTGGTAACCTCACCCTCACCGTTTTCGGAGTCACTCTCGAAGGCATC
GCATGGGGCTCTGTAGGCATCATTGTGCTGTACCCAATCATGAAGCGCCTGTACCTTTCCATTGGGGAAGGCAAGAACGC
AAAGTTCTAG

Upstream 100 bases:

>100_bases
ATCCCCACCCAATTGGCCCAAGAGCTGCAGAGTTACGTTGTAGAACCCACCTCTACCTAACTGTCGATTTCCCAAGAGCC
CCCTTGGGAGTCGATAATTA

Downstream 100 bases:

>100_bases
TACGCTGCTAAAGTATGCAGCTTGGCCCGCACGGTTTCCGCGTGCGGGACGTGTTCATTTCTGTATAGGAAAACTACCTT
GATCGTTGATACCCAGTTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MLVTSTWGWTVHGDGKKIEPGAVVAPKERLSWGRTIGIGMQHVIAMFGATLLVPTLTGFPVNTTLLFSGLGTILFLLITR
NRLPSYLGSSFAFIAPLTATQVHGIGVQIGGILVAGLVLVAIGFVVKAAGKRVIDAVMPPAVTGAIVALIGLNLAPTAAG
NFSSQPLVATVTLFAILIATVAGRGMIARLGILIGVVIGWVFAAITGNLSEGAADTIREAAWFGLPQFHKPEFQLSAILV
TLPVIIVLIAENVGHVKAVSEMTGEDLDDLAGDALIADGFGTTLAGAFGGSGTTTYAENIGVMAATRVYSTAAYWVAACT
AIALAFIPKFGALIFTIPAGVLGGACLVLYGLIGMLGIRIWQDNKVNFNNPVNLTMAAVALVAGIGNLTLTVFGVTLEGI
AWGSVGIIVLYPIMKRLYLSIGEGKNAKF

Sequences:

>Translated_429_residues
MLVTSTWGWTVHGDGKKIEPGAVVAPKERLSWGRTIGIGMQHVIAMFGATLLVPTLTGFPVNTTLLFSGLGTILFLLITR
NRLPSYLGSSFAFIAPLTATQVHGIGVQIGGILVAGLVLVAIGFVVKAAGKRVIDAVMPPAVTGAIVALIGLNLAPTAAG
NFSSQPLVATVTLFAILIATVAGRGMIARLGILIGVVIGWVFAAITGNLSEGAADTIREAAWFGLPQFHKPEFQLSAILV
TLPVIIVLIAENVGHVKAVSEMTGEDLDDLAGDALIADGFGTTLAGAFGGSGTTTYAENIGVMAATRVYSTAAYWVAACT
AIALAFIPKFGALIFTIPAGVLGGACLVLYGLIGMLGIRIWQDNKVNFNNPVNLTMAAVALVAGIGNLTLTVFGVTLEGI
AWGSVGIIVLYPIMKRLYLSIGEGKNAKF
>Mature_429_residues
MLVTSTWGWTVHGDGKKIEPGAVVAPKERLSWGRTIGIGMQHVIAMFGATLLVPTLTGFPVNTTLLFSGLGTILFLLITR
NRLPSYLGSSFAFIAPLTATQVHGIGVQIGGILVAGLVLVAIGFVVKAAGKRVIDAVMPPAVTGAIVALIGLNLAPTAAG
NFSSQPLVATVTLFAILIATVAGRGMIARLGILIGVVIGWVFAAITGNLSEGAADTIREAAWFGLPQFHKPEFQLSAILV
TLPVIIVLIAENVGHVKAVSEMTGEDLDDLAGDALIADGFGTTLAGAFGGSGTTTYAENIGVMAATRVYSTAAYWVAACT
AIALAFIPKFGALIFTIPAGVLGGACLVLYGLIGMLGIRIWQDNKVNFNNPVNLTMAAVALVAGIGNLTLTVFGVTLEGI
AWGSVGIIVLYPIMKRLYLSIGEGKNAKF

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081818, Length=408, Percent_Identity=47.7941176470588, Blast_Score=333, Evalue=2e-92,
Organism=Escherichia coli, GI1788843, Length=397, Percent_Identity=40.3022670025189, Blast_Score=254, Evalue=8e-69,
Organism=Escherichia coli, GI87082181, Length=394, Percent_Identity=28.9340101522843, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1790087, Length=385, Percent_Identity=25.7142857142857, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082178, Length=239, Percent_Identity=26.7782426778243, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17558856, Length=170, Percent_Identity=32.9411764705882, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356175, Length=423, Percent_Identity=25.2955082742317, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 44326; Mature: 44326

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVTSTWGWTVHGDGKKIEPGAVVAPKERLSWGRTIGIGMQHVIAMFGATLLVPTLTGFP
CEEEECCCEEEECCCCEECCCCEECCHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCC
VNTTLLFSGLGTILFLLITRNRLPSYLGSSFAFIAPLTATQVHGIGVQIGGILVAGLVLV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHCCCCCCHHHHHHHHHHHHH
AIGFVVKAAGKRVIDAVMPPAVTGAIVALIGLNLAPTAAGNFSSQPLVATVTLFAILIAT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VAGRGMIARLGILIGVVIGWVFAAITGNLSEGAADTIREAAWFGLPQFHKPEFQLSAILV
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TLPVIIVLIAENVGHVKAVSEMTGEDLDDLAGDALIADGFGTTLAGAFGGSGTTTYAENI
HHHHHHHHHHCCCCHHHHHHHHCCCCHHHHCCCEEEECCCCHHHHHCCCCCCCCHHHHCC
GVMAATRVYSTAAYWVAACTAIALAFIPKFGALIFTIPAGVLGGACLVLYGLIGMLGIRI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
WQDNKVNFNNPVNLTMAAVALVAGIGNLTLTVFGVTLEGIAWGSVGIIVLYPIMKRLYLS
EECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCEEECCHHHHHHHHHHHHHHHH
IGEGKNAKF
CCCCCCCCC
>Mature Secondary Structure
MLVTSTWGWTVHGDGKKIEPGAVVAPKERLSWGRTIGIGMQHVIAMFGATLLVPTLTGFP
CEEEECCCEEEECCCCEECCCCEECCHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCC
VNTTLLFSGLGTILFLLITRNRLPSYLGSSFAFIAPLTATQVHGIGVQIGGILVAGLVLV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHCCCCCCHHHHHHHHHHHHH
AIGFVVKAAGKRVIDAVMPPAVTGAIVALIGLNLAPTAAGNFSSQPLVATVTLFAILIAT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VAGRGMIARLGILIGVVIGWVFAAITGNLSEGAADTIREAAWFGLPQFHKPEFQLSAILV
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TLPVIIVLIAENVGHVKAVSEMTGEDLDDLAGDALIADGFGTTLAGAFGGSGTTTYAENI
HHHHHHHHHHCCCCHHHHHHHHCCCCHHHHCCCEEEECCCCHHHHHCCCCCCCCHHHHCC
GVMAATRVYSTAAYWVAACTAIALAFIPKFGALIFTIPAGVLGGACLVLYGLIGMLGIRI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
WQDNKVNFNNPVNLTMAAVALVAGIGNLTLTVFGVTLEGIAWGSVGIIVLYPIMKRLYLS
EECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCEEECCHHHHHHHHHHHHHHHH
IGEGKNAKF
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]