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The map label for this gene is yfmC [H]

Identifier: 145294814

GI number: 145294814

Start: 840484

End: 841482

Strand: Direct

Name: yfmC [H]

Synonym: cgR_0761

Alternate gene names: 145294814

Gene position: 840484-841482 (Clockwise)

Preceding gene: 145294813

Following gene: 145294816

Centisome position: 25.36

GC content: 50.55

Gene sequence:

>999_bases
GTGCAATCCCGCCTGTCCAAAATCCTGCGCAGTAGCGTCGTAGGCGTTGCAGTCCTAGCCCTGTTAGCTGGGTGTTCTAG
CAATGCAGATGACACCGACGCTGATTCAACATCCACGGGAAACTCCGCTTTTCCTGTTTCGATTGAACACGAGTTCGGAA
CCACCACAATCGATGATGTACCCGAAAGAATTGTCACCCTTGGCGTTACCGACGCCGATATTGTCCTCGCATTGGGGACC
GTCCCAGTAGGCAACACCGGATACAAATTCTTCGAAAACGGATTGGGACCGTGGACTGATGAGTTAGTGGAAGGCAAAGA
ATTAACACTGCTTGACTCTGATTCCACACCAGATCTTGAACAAGTAGCAGTCCTGGAGCCAGACCTAATTATTGGAGTCT
CTGCGGGGTTTGACGACGTTGTATACGAGCAACTATCTGATATCGCACCGGTGGTCGCCCGTCCAGCGGGAACAGCTGCA
TACGCAGTAGCTCGCGAGGAAGCTACCAGCCTTGTTGCCCGTGCGATGGGGCAATCAGAAAAAGGACAAGAGCTCAATGA
GGAAACGGATGCTCTGATCCAAGCTGCGCGTGATGAAAATCCTTCTTTTGACGGTAAAACAGGAACCGTCATCTTGCCAT
ACCAGGGTAAATACGGTGCCTACCTGCCAGGCGATACACGGGGACAATTCCTCGATTCACTTGGCATTTCGCTGCCGGAA
GCAGTTCTTTCGCGAGACACCGGCGACAGCTTCTTCGTTGATGTTCCCGCTGAAAGCGTCAAAGACGTTGACGGTGATGT
TCTACTTGTGCTTTCTAACGATGAAAATCTGGATATCACAGCAGAGAATCCACTGTTTGAAACACTCAACGTTGTGCAAA
ATGATGCAGTAATTGTGGCAACAACCGAAGAACGCGGGGCGATTACCTACAACTCAGTGCTGTCTGTTCCTTTTGCGTTG
GAACATCTCGCACCACGTATTGCTGAGGCTTTGAAGTAA

Upstream 100 bases:

>100_bases
TTTAAAAGCGCACTAAGAGCTCGTCAATTCTTTAAAACAAGCTGAGAATGTGAATAATAGGATAGGTTAACCTGATTCGA
TTAGAAAACGGAGATTTGTC

Downstream 100 bases:

>100_bases
AACTCAACTACTCGAGCACAATCAAATGAAACCACCCCGGAGATGAACTGCCCCGGGGTGTTTTTCTAATAAGGCACATG
CCTGATCCAGAAGCCCGGTG

Product: hypothetical protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric-citrate-binding protein [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MQSRLSKILRSSVVGVAVLALLAGCSSNADDTDADSTSTGNSAFPVSIEHEFGTTTIDDVPERIVTLGVTDADIVLALGT
VPVGNTGYKFFENGLGPWTDELVEGKELTLLDSDSTPDLEQVAVLEPDLIIGVSAGFDDVVYEQLSDIAPVVARPAGTAA
YAVAREEATSLVARAMGQSEKGQELNEETDALIQAARDENPSFDGKTGTVILPYQGKYGAYLPGDTRGQFLDSLGISLPE
AVLSRDTGDSFFVDVPAESVKDVDGDVLLVLSNDENLDITAENPLFETLNVVQNDAVIVATTEERGAITYNSVLSVPFAL
EHLAPRIAEALK

Sequences:

>Translated_332_residues
MQSRLSKILRSSVVGVAVLALLAGCSSNADDTDADSTSTGNSAFPVSIEHEFGTTTIDDVPERIVTLGVTDADIVLALGT
VPVGNTGYKFFENGLGPWTDELVEGKELTLLDSDSTPDLEQVAVLEPDLIIGVSAGFDDVVYEQLSDIAPVVARPAGTAA
YAVAREEATSLVARAMGQSEKGQELNEETDALIQAARDENPSFDGKTGTVILPYQGKYGAYLPGDTRGQFLDSLGISLPE
AVLSRDTGDSFFVDVPAESVKDVDGDVLLVLSNDENLDITAENPLFETLNVVQNDAVIVATTEERGAITYNSVLSVPFAL
EHLAPRIAEALK
>Mature_332_residues
MQSRLSKILRSSVVGVAVLALLAGCSSNADDTDADSTSTGNSAFPVSIEHEFGTTTIDDVPERIVTLGVTDADIVLALGT
VPVGNTGYKFFENGLGPWTDELVEGKELTLLDSDSTPDLEQVAVLEPDLIIGVSAGFDDVVYEQLSDIAPVVARPAGTAA
YAVAREEATSLVARAMGQSEKGQELNEETDALIQAARDENPSFDGKTGTVILPYQGKYGAYLPGDTRGQFLDSLGISLPE
AVLSRDTGDSFFVDVPAESVKDVDGDVLLVLSNDENLDITAENPLFETLNVVQNDAVIVATTEERGAITYNSVLSVPFAL
EHLAPRIAEALK

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Binds citrate-dependent Fe(3+) and delivers it to the surface of yfmDE (Probable) [H]

COG id: COG0614

COG function: function code P; ABC-type Fe3+-hydroxamate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082411, Length=267, Percent_Identity=25.4681647940075, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 35080; Mature: 35080

Theoretical pI: Translated: 3.78; Mature: 3.78

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSRLSKILRSSVVGVAVLALLAGCSSNADDTDADSTSTGNSAFPVSIEHEFGTTTIDDV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHH
PERIVTLGVTDADIVLALGTVPVGNTGYKFFENGLGPWTDELVEGKELTLLDSDSTPDLE
HHHHEEECCCCCCEEEEEECCCCCCCCHHHHHCCCCCCHHHHHCCCEEEEEECCCCCCHH
QVAVLEPDLIIGVSAGFDDVVYEQLSDIAPVVARPAGTAAYAVAREEATSLVARAMGQSE
HEEEECCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
KGQELNEETDALIQAARDENPSFDGKTGTVILPYQGKYGAYLPGDTRGQFLDSLGISLPE
CCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCHH
AVLSRDTGDSFFVDVPAESVKDVDGDVLLVLSNDENLDITAENPLFETLNVVQNDAVIVA
HHHCCCCCCEEEEECCHHHHCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHCCCEEEEE
TTEERGAITYNSVLSVPFALEHLAPRIAEALK
ECCCCCCEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQSRLSKILRSSVVGVAVLALLAGCSSNADDTDADSTSTGNSAFPVSIEHEFGTTTIDDV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHH
PERIVTLGVTDADIVLALGTVPVGNTGYKFFENGLGPWTDELVEGKELTLLDSDSTPDLE
HHHHEEECCCCCCEEEEEECCCCCCCCHHHHHCCCCCCHHHHHCCCEEEEEECCCCCCHH
QVAVLEPDLIIGVSAGFDDVVYEQLSDIAPVVARPAGTAAYAVAREEATSLVARAMGQSE
HEEEECCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
KGQELNEETDALIQAARDENPSFDGKTGTVILPYQGKYGAYLPGDTRGQFLDSLGISLPE
CCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCHH
AVLSRDTGDSFFVDVPAESVKDVDGDVLLVLSNDENLDITAENPLFETLNVVQNDAVIVA
HHHCCCCCCEEEEECCHHHHCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHCCCEEEEE
TTEERGAITYNSVLSVPFALEHLAPRIAEALK
ECCCCCCEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]