| Definition | Corynebacterium glutamicum R chromosome, complete genome. |
|---|---|
| Accession | NC_009342 |
| Length | 3,314,179 |
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The map label for this gene is echA8 [H]
Identifier: 145294706
GI number: 145294706
Start: 711655
End: 712404
Strand: Direct
Name: echA8 [H]
Synonym: cgR_0654
Alternate gene names: 145294706
Gene position: 711655-712404 (Clockwise)
Preceding gene: 145294705
Following gene: 145294707
Centisome position: 21.47
GC content: 51.47
Gene sequence:
>750_bases ATGAGCTTTGATTTTGATGCTTTGACCATCACGGAATCTGACGACCTTTTGATCATCGAGCTTTCTCGGCCAGAGGTCCG TAACGCCATTGACCAAACCATGGTCAATGAGCTTCATGAGGTCTGTGCCTACCTGGAGGAAAATCCTAAGACTGCGATCA TCATTGGATCGGATGGCATTTTTGCCTCTGGTGCAGATATCGGTCAGTTGCGTGAGCGTCGACGTGAAGATGCACTTCGG GGAATTAACAATTCCATTTTCCACCGCATTGCGCAGCTTCCGATGCCGGTGATCGCGGCTGTTGACGGATTCGCTCTGGG TGGAGGACTGGAACTTGCGTTGGCTGCTGATTTCCGGGTGGCTACGCAGAACGCAAAGTTTGGTCAGCCAGAAGCAAGCC TGGGAATCATGGCTGCAGCTGGTGGAACCTGGCGTTTGAAGGCAGCAGTGGGAGAGCCTTTGGCTAAGGATATTTTGTTG GCTGGCCGCATTATTGATGGTGAAGAAGCGAAGACCTACCAGTTGGTTTCCAATCTTGCCCCAGCTGAAGACCTGCTTGA TGAGGCTAAGAAACTAGCGCAGCGCATTGGAAAGCTTGATCCTTTGGCGGTGCGAATTACAAAATCTGTCATGGCGTTGC CGGAGTCCGCGCACCCGCAGGCAGATAATTTGGCGCAGGCGATTCTCTTTGAATCTGAAGCGAAGTTTGATCGCATGCAA GCATTTCTCGACCGCAAGAAGAGCAAGTAA
Upstream 100 bases:
>100_bases TAACCGCCTGGAAAAAGAAGGCGGATCCAAGGGCATTGCCACCATGTGTATCGGAGTCGGTCAGGGCTCCGCGATCGCTA TCGAAAGGGTGTAGTTAATC
Downstream 100 bases:
>100_bases AAAGAACAGGTAAGGAACTTAAAATATGTCTAGTGAAATCACAGTGCCAAACAAAGTTGGTGTGCTCGGTGGCGGTCGCA TGGGTGGAGGCATTGCGCAC
Product: hypothetical protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 249; Mature: 248
Protein sequence:
>249_residues MSFDFDALTITESDDLLIIELSRPEVRNAIDQTMVNELHEVCAYLEENPKTAIIIGSDGIFASGADIGQLRERRREDALR GINNSIFHRIAQLPMPVIAAVDGFALGGGLELALAADFRVATQNAKFGQPEASLGIMAAAGGTWRLKAAVGEPLAKDILL AGRIIDGEEAKTYQLVSNLAPAEDLLDEAKKLAQRIGKLDPLAVRITKSVMALPESAHPQADNLAQAILFESEAKFDRMQ AFLDRKKSK
Sequences:
>Translated_249_residues MSFDFDALTITESDDLLIIELSRPEVRNAIDQTMVNELHEVCAYLEENPKTAIIIGSDGIFASGADIGQLRERRREDALR GINNSIFHRIAQLPMPVIAAVDGFALGGGLELALAADFRVATQNAKFGQPEASLGIMAAAGGTWRLKAAVGEPLAKDILL AGRIIDGEEAKTYQLVSNLAPAEDLLDEAKKLAQRIGKLDPLAVRITKSVMALPESAHPQADNLAQAILFESEAKFDRMQ AFLDRKKSK >Mature_248_residues SFDFDALTITESDDLLIIELSRPEVRNAIDQTMVNELHEVCAYLEENPKTAIIIGSDGIFASGADIGQLRERRREDALRG INNSIFHRIAQLPMPVIAAVDGFALGGGLELALAADFRVATQNAKFGQPEASLGIMAAAGGTWRLKAAVGEPLAKDILLA GRIIDGEEAKTYQLVSNLAPAEDLLDEAKKLAQRIGKLDPLAVRITKSVMALPESAHPQADNLAQAILFESEAKFDRMQA FLDRKKSK
Specific function: Could possibly oxidize fatty acids using specific components [H]
COG id: COG1024
COG function: function code I; Enoyl-CoA hydratase/carnithine racemase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=243, Percent_Identity=34.5679012345679, Blast_Score=141, Evalue=5e-34, Organism=Homo sapiens, GI68989263, Length=208, Percent_Identity=34.1346153846154, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI20127408, Length=174, Percent_Identity=32.7586206896552, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI4502327, Length=209, Percent_Identity=36.3636363636364, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI31542718, Length=251, Percent_Identity=27.8884462151394, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI70995211, Length=238, Percent_Identity=30.2521008403361, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI37594469, Length=246, Percent_Identity=26.0162601626016, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI37594471, Length=246, Percent_Identity=26.0162601626016, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI213417737, Length=210, Percent_Identity=29.0476190476191, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI157694516, Length=210, Percent_Identity=29.0476190476191, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI260274832, Length=263, Percent_Identity=24.3346007604563, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI45643119, Length=263, Percent_Identity=24.3346007604563, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI260275230, Length=263, Percent_Identity=24.3346007604563, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI261878539, Length=113, Percent_Identity=37.1681415929204, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1787659, Length=248, Percent_Identity=34.6774193548387, Blast_Score=136, Evalue=1e-33, Organism=Escherichia coli, GI221142681, Length=209, Percent_Identity=36.8421052631579, Blast_Score=114, Evalue=4e-27, Organism=Escherichia coli, GI1790281, Length=209, Percent_Identity=33.0143540669856, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1788682, Length=232, Percent_Identity=31.0344827586207, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI1788597, Length=206, Percent_Identity=28.6407766990291, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI87082183, Length=261, Percent_Identity=22.6053639846743, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787660, Length=193, Percent_Identity=29.0155440414508, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17554946, Length=246, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=2e-31, Organism=Caenorhabditis elegans, GI17540714, Length=208, Percent_Identity=35.5769230769231, Blast_Score=129, Evalue=2e-30, Organism=Caenorhabditis elegans, GI25145438, Length=243, Percent_Identity=34.5679012345679, Blast_Score=128, Evalue=2e-30, Organism=Caenorhabditis elegans, GI17560910, Length=186, Percent_Identity=30.1075268817204, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17534483, Length=231, Percent_Identity=29.004329004329, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17536985, Length=226, Percent_Identity=27.4336283185841, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17549921, Length=208, Percent_Identity=24.5192307692308, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17558304, Length=179, Percent_Identity=28.4916201117318, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI25144276, Length=146, Percent_Identity=30.1369863013699, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17508951, Length=146, Percent_Identity=30.1369863013699, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17508953, Length=146, Percent_Identity=30.1369863013699, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17540306, Length=191, Percent_Identity=29.8429319371728, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17535521, Length=219, Percent_Identity=23.7442922374429, Blast_Score=64, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6320241, Length=210, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=2e-14, Organism=Drosophila melanogaster, GI20129971, Length=229, Percent_Identity=34.9344978165939, Blast_Score=131, Evalue=4e-31, Organism=Drosophila melanogaster, GI24653477, Length=229, Percent_Identity=34.9344978165939, Blast_Score=131, Evalue=4e-31, Organism=Drosophila melanogaster, GI24653139, Length=200, Percent_Identity=37, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI19920382, Length=223, Percent_Identity=32.7354260089686, Blast_Score=92, Evalue=2e-19, Organism=Drosophila melanogaster, GI21357171, Length=196, Percent_Identity=30.6122448979592, Blast_Score=91, Evalue=8e-19, Organism=Drosophila melanogaster, GI24650670, Length=199, Percent_Identity=31.1557788944724, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI19921000, Length=172, Percent_Identity=34.8837209302326, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI24583077, Length=172, Percent_Identity=34.8837209302326, Blast_Score=83, Evalue=1e-16, Organism=Drosophila melanogaster, GI24583079, Length=172, Percent_Identity=34.8837209302326, Blast_Score=83, Evalue=1e-16, Organism=Drosophila melanogaster, GI19922422, Length=200, Percent_Identity=24, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI28571730, Length=148, Percent_Identity=30.4054054054054, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI28571729, Length=148, Percent_Identity=30.4054054054054, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24654903, Length=187, Percent_Identity=24.0641711229947, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: =4.2.1.17 [H]
Molecular weight: Translated: 26993; Mature: 26862
Theoretical pI: Translated: 4.73; Mature: 4.73
Prosite motif: PS00166 ENOYL_COA_HYDRATASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSFDFDALTITESDDLLIIELSRPEVRNAIDQTMVNELHEVCAYLEENPKTAIIIGSDGI CCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC FASGADIGQLRERRREDALRGINNSIFHRIAQLPMPVIAAVDGFALGGGLELALAADFRV EECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHCCEEECCCEEEEEEECEEE ATQNAKFGQPEASLGIMAAAGGTWRLKAAVGEPLAKDILLAGRIIDGEEAKTYQLVSNLA EECCCCCCCCCCCCEEEEECCCCEEEEHHHCCHHHHHHHHHCEEECCCCHHHHHHHHHCC PAEDLLDEAKKLAQRIGKLDPLAVRITKSVMALPESAHPQADNLAQAILFESEAKFDRMQ CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHH AFLDRKKSK HHHHHHCCC >Mature Secondary Structure SFDFDALTITESDDLLIIELSRPEVRNAIDQTMVNELHEVCAYLEENPKTAIIIGSDGI CCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC FASGADIGQLRERRREDALRGINNSIFHRIAQLPMPVIAAVDGFALGGGLELALAADFRV EECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHCCEEECCCEEEEEEECEEE ATQNAKFGQPEASLGIMAAAGGTWRLKAAVGEPLAKDILLAGRIIDGEEAKTYQLVSNLA EECCCCCCCCCCCCEEEEECCCCEEEEHHHCCHHHHHHHHHCEEECCCCHHHHHHHHHCC PAEDLLDEAKKLAQRIGKLDPLAVRITKSVMALPESAHPQADNLAQAILFESEAKFDRMQ CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHH AFLDRKKSK HHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 12788972 [H]