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The map label for this gene is ccdA [H]

Identifier: 145294559

GI number: 145294559

Start: 570395

End: 571201

Strand: Direct

Name: ccdA [H]

Synonym: cgR_0510

Alternate gene names: 145294559

Gene position: 570395-571201 (Clockwise)

Preceding gene: 145294558

Following gene: 145294560

Centisome position: 17.21

GC content: 58.86

Gene sequence:

>807_bases
ATGTCTGAGATTGTGGTAGCCCAAAGCATCGGCCAGCAGTTTGCTGACGTCGCAGCTTCCGGGCCACTGTTCCTTGGCAT
CCTTGCCGCAGCGCTCGCAGGTCTGGTGTCTTTTGCCAGCCCTTGTGTGGTGCCGTTGGTGCCCGGATATATTTCCTACC
TCGCCGGCGTGGTCGGTGGGGAAGTGGAATACAGCGCGCAGGGCACCAAGGTGAAAACCAAGCGTTTCGCCGTGGGTGGC
GCAGCCATGCTGTTCATCCTGGGATTCACCGTGGTGTTCGTGCTGGCTACGGTCAGTGTGTTTGGTGCCATCAGCGTGCT
CACCCTAAACGCCGACACCCTCATGCGTATCGGCGGCGTGGTGACCATCATCATGGGCATCGTATTCATGGGCTTCATTC
CAGGCCTGCAGCGCGATACCCGCATGGCACCAAAGCGTTGGACCACCTGGTTGGGTGCGCCCCTTCTTGGCGGAGTGTTC
GCTCTCGGTTGGACCCCTTGTTTGGGCCCCACCCTGGCTGCGATCATCTCCATTTCTGCAGGTACTGAAGGTATGACCGC
TGCGCGTGGCGTGATCTTAATTGTGGGTTACTGCCTCGGACTGGGGCTGCCGTTCCTGCTGATCGCGTTGGGCTCCAGCA
AGGCACTCACCGGAGTCGAGTGGTTGCGCAAGCATTCCCGCACCCTGCAAATTATCGGCGGTGTGCTTTTGATCTTGGTC
GGAGTAGCGTTGCTCTCTGGCTCATGGGCAATTTTTATCAACTGGGTCCGTCAGTGGACCGTTGAATACGGCGCAACACT
GCTCTAG

Upstream 100 bases:

>100_bases
CGTGCTGGATAAACAGCACCGCCCCGCAGCAGTGTTCTTGCGCGAAGTCACCTCCAAAGATGTGTTGGATGTTGCGTTGC
CATTGGTAGATGAGGCCTAA

Downstream 100 bases:

>100_bases
AAAAAGACTTTTAGTAGGAAGAGAATCGGCACGACAATGCTCAAAACAGTCAAGCTGTATGCACGGAAAGCGTGGAACTG
GCTCACCAGCATGCGCACAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSEIVVAQSIGQQFADVAASGPLFLGILAAALAGLVSFASPCVVPLVPGYISYLAGVVGGEVEYSAQGTKVKTKRFAVGG
AAMLFILGFTVVFVLATVSVFGAISVLTLNADTLMRIGGVVTIIMGIVFMGFIPGLQRDTRMAPKRWTTWLGAPLLGGVF
ALGWTPCLGPTLAAIISISAGTEGMTAARGVILIVGYCLGLGLPFLLIALGSSKALTGVEWLRKHSRTLQIIGGVLLILV
GVALLSGSWAIFINWVRQWTVEYGATLL

Sequences:

>Translated_268_residues
MSEIVVAQSIGQQFADVAASGPLFLGILAAALAGLVSFASPCVVPLVPGYISYLAGVVGGEVEYSAQGTKVKTKRFAVGG
AAMLFILGFTVVFVLATVSVFGAISVLTLNADTLMRIGGVVTIIMGIVFMGFIPGLQRDTRMAPKRWTTWLGAPLLGGVF
ALGWTPCLGPTLAAIISISAGTEGMTAARGVILIVGYCLGLGLPFLLIALGSSKALTGVEWLRKHSRTLQIIGGVLLILV
GVALLSGSWAIFINWVRQWTVEYGATLL
>Mature_267_residues
SEIVVAQSIGQQFADVAASGPLFLGILAAALAGLVSFASPCVVPLVPGYISYLAGVVGGEVEYSAQGTKVKTKRFAVGGA
AMLFILGFTVVFVLATVSVFGAISVLTLNADTLMRIGGVVTIIMGIVFMGFIPGLQRDTRMAPKRWTTWLGAPLLGGVFA
LGWTPCLGPTLAAIISISAGTEGMTAARGVILIVGYCLGLGLPFLLIALGSSKALTGVEWLRKHSRTLQIIGGVLLILVG
VALLSGSWAIFINWVRQWTVEYGATLL

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 27857; Mature: 27726

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SEIVVAQSIGQQFADVAASGPLFLGILAAALAGLVSFASPCVVPLVPGYISYLAGVVGG
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
EVEYSAQGTKVKTKRFAVGGAAMLFILGFTVVFVLATVSVFGAISVLTLNADTLMRIGGV
CEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHH
VTIIMGIVFMGFIPGLQRDTRMAPKRWTTWLGAPLLGGVFALGWTPCLGPTLAAIISISA
HHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHCC
GTEGMTAARGVILIVGYCLGLGLPFLLIALGSSKALTGVEWLRKHSRTLQIIGGVLLILV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GVALLSGSWAIFINWVRQWTVEYGATLL
HHHHHCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]